Patents by Inventor Jason A. Crawford

Jason A. Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7354932
    Abstract: The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
    Type: Grant
    Filed: June 6, 2003
    Date of Patent: April 8, 2008
    Assignee: Anormed, Inc.
    Inventors: Gary Bridger, Al Kaller, Curtis Harwig, Renato Skerlj, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis Smith, Maria Rosaria Di Fluri
  • Publication number: 20080039119
    Abstract: A method and an apparatus for radiolocation using time differences of arrival. The method includes receiving transmit timestamps from a set of wireless stations of a wireless network. Each station transmits at least once. The transmit timestamp uses a local timestamping clock to indicate when a station transmitted a packet. The method further includes receiving sets of timestamped captured samples from each station that receives one of the transmitted packets. The times of arrival of each packet at each station are determined from the received sets of timestamped captured samples, and, the relative positions of the stations are determined from the determined times of arrival and the received transmit timestamps. The transmitting by the stations is in a round robin manner one station after the other, and several round robins may be used to mutually calibrate local clocks. Also an apparatus for inclusion in a station of a wireless network.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 14, 2008
    Inventors: Jason Crawford, John O'Sullivan, Brian Hart
  • Patent number: 7312234
    Abstract: Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.
    Type: Grant
    Filed: August 9, 2004
    Date of Patent: December 25, 2007
    Assignee: AnorMED
    Inventors: Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis Smith, Maria Rosaria Di Fluri
  • Publication number: 20070188376
    Abstract: A method for radar protection. The method includes recording energy events and calculating differences in recorded energy events to determine pulses. The method further includes sorting intervals between pulses into histogram bins, each bin representing a range of time intervals between two pulses, each pulse indicative of a radar frequency and limiting network traffic on a frequency based on a selected bin count.
    Type: Application
    Filed: April 19, 2007
    Publication date: August 16, 2007
    Inventors: David Theobold, Christopher Meil, Edward Wright, James Amos, Brian Hart, Jason Crawford, Philip O'Sullivan, Kevin Wong
  • Patent number: 7183273
    Abstract: Heterocyclic compounds that bind chemokine receptors and inhibit the binding of their natural ligands are disclosed. The invention compounds are protective against infection by HIV and exert effects characteristic of antagonists to the CXCR4 receptor.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: February 27, 2007
    Assignee: AnorMED, Inc.
    Inventors: Gary J. Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols
  • Publication number: 20060264434
    Abstract: This invention relates to a novel class of heterocyclic compounds that bind chemokine receptors, inhibiting the binding of their natural ligands thereby. These compounds result in protective effects against infection by HIV through binding to chemokine receptors, including CXCR4 and CCR5, thus inhibiting the subsequent binding by these chemokines.
    Type: Application
    Filed: July 27, 2006
    Publication date: November 23, 2006
    Applicant: AnorMED Inc.
    Inventors: Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor Wilson, Jason Crawford, Ernest McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols
  • Publication number: 20060252795
    Abstract: Compounds which modulate chemokine receptor activities are disclosed. These compounds are preferably tertiary amines comprising tetrahydroquinoline and benzimidazole.
    Type: Application
    Filed: July 14, 2006
    Publication date: November 9, 2006
    Inventors: Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor Wilson, Jason Crawford, Ernest McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Smith, Maria Di Fluri
  • Patent number: 7091217
    Abstract: Compounds which modulate chemokine receptor activities are disclosed. These compounds are preferably tertiary amines comprising tetrahydroquinoline and benzimidazole.
    Type: Grant
    Filed: March 11, 2004
    Date of Patent: August 15, 2006
    Assignee: AnorMED, Inc.
    Inventors: Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis Smith, Maria Rosaria Di Fluri
  • Patent number: 7084155
    Abstract: Novel compounds that are useful for targeting chemokine receptors are disclosed. These compounds are complex tertiary amines.
    Type: Grant
    Filed: June 1, 2004
    Date of Patent: August 1, 2006
    Assignee: AnorMED
    Inventors: Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis Smith, Maria Rosaria Di Fluri
  • Publication number: 20060149820
    Abstract: A method for detecting undesirable e-mails is disclosed. The method includes collecting a plurality of undesirable e-mails, arranging the plurality of undesirable e-mails into a plurality of groups and generating, for each group, at least one token, thereby producing a plurality of tokens for the plurality of undesirable e-mails. The method further includes receiving a first e-mail and generating at least one token for the first e-mail. The method further includes causing a comparison of the at least one token for the first e-mail with at least one of the plurality of tokens for the plurality of undesirable e-mails and identifying the first e-mail as an undesirable e-mail if the at least one token for the first e-mail matches any of the plurality of tokens for the plurality of undesirable e-mails.
    Type: Application
    Filed: January 4, 2005
    Publication date: July 6, 2006
    Inventors: Vadakkedathu Rajan, Mark Wegman, Richard Segal, Jason Crawford, Joel Ossher, Jeffrey Kephart
  • Publication number: 20060149821
    Abstract: A method for detecting undesirable emails is disclosed. The method combines input from two or more spam classifiers to provide improved classification effectiveness and robustness. The method's effectiveness is improved over that of any one constituent classifier in the sense that the detection rate is increased and/or the false positive rate is decreased. The method's robustness is improved in the sense that, if spammers temporarily elude any one constituent classifier, the other constituent classifiers will still be likely to catch the spam. The method includes obtaining a score from each of a plurality of constituent spam classifiers by applying them to a given input email. The method further includes obtaining a combined spam score from a combined spam classifier that takes as input the plurality of constituent spam classifier scores, the combined spam classifier being computed automatically in accordance with a specified false-positive vs. false-negative tradeoff.
    Type: Application
    Filed: January 4, 2005
    Publication date: July 6, 2006
    Inventors: Vadakkedathu Rajan, Mark Wegman, Richard Segal, Jason Crawford, Jeffrey Kephart, Shlomo Hershkop
  • Publication number: 20060128750
    Abstract: Tertiary amine compounds that bind chemokine receptors such as CXCR4 and CCR5 are disclosed.
    Type: Application
    Filed: February 2, 2006
    Publication date: June 15, 2006
    Inventors: Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor Wilson, Jason Crawford, Ernest McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Smith, Maria Di Fluri
  • Publication number: 20060100240
    Abstract: The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
    Type: Application
    Filed: December 13, 2005
    Publication date: May 11, 2006
    Inventors: Gary Bridger, Ai Kaller, Curtis Harwig, Renato Skerlj, David Bogucki, Trevor Wilson, Jason Crawford, Ernest McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Smith, Maria Di Fluri
  • Publication number: 20060070656
    Abstract: An apparatus is provided for controlling discharge of fuel vapor from an interior region in a fuel tank and preventing unsatisfactory liquid fuel levels within the interior region of the fuel tank. The apparatus includes a buoyant fill-limit valve movable to open and close a vapor outlet opening.
    Type: Application
    Filed: October 1, 2004
    Publication date: April 6, 2006
    Inventor: Jason Crawford
  • Publication number: 20060069122
    Abstract: The present invention relates to chemokine-binding heterocyclic compound salts, methods of use thereof, and methods for preparing the same.
    Type: Application
    Filed: September 26, 2005
    Publication date: March 30, 2006
    Inventors: Jason Crawford, Yongbao Zhu, Gang Chen, Ian Baird, Renato Skerlj
  • Publication number: 20050209277
    Abstract: This invention relates to a process for synthesizing heterocyclic pharmaceutical compound which binds to the CXCR4 chemokine receptor.
    Type: Application
    Filed: March 11, 2005
    Publication date: September 22, 2005
    Inventors: Jason Crawford, Gang Chen, David Gauthier, Renato Skerlj, Ian Baird, Trevor Wilson
  • Publication number: 20050195744
    Abstract: An apparatus in a node of a wireless network for setting the data rate for sending data to a remote node, and a method for setting the data rate. The method includes receiving a packet from the remote node, determining a measure of signal quality for the received packet; and selecting the data rate for communicating to the remote node according to at least the determined signal quality. The measure of signal quality is a measure of the EVM of the received packet. One implementation conforms to one or more variants of the IEEE 802.11 standard that uses OFDM packets.
    Type: Application
    Filed: April 5, 2005
    Publication date: September 8, 2005
    Inventors: Philip Ryan, Andrew Adams, Brian Hart, Jason Crawford, Andrew Myles
  • Publication number: 20050165895
    Abstract: In an electronic mail system, an apparatus and method for providing, in addition to the conventional “Inbox” directory in which all incoming e-mails are normally received, a plurality of appropriately labeled directories for containing e-mails suspected of being spam, grading the level of spaminess of the incoming e-mails and then moving or copying the incoming e-mails into one or more of the spam directories based upon the e-mails' respective levels of spaminess.
    Type: Application
    Filed: January 23, 2004
    Publication date: July 28, 2005
    Inventors: Vadakkedathu Rajan, Jason Crawford, Mark Wegman
  • Publication number: 20050154201
    Abstract: Methods for preparing 2,6-diaryl piperidine derivatives are described. More particularly, 2,6-diaryl piperidines having formula 1-4 are prepared by cyclocondensation of an aryl or heteroaryl aldehyde with 1,3-acetonedicarboxylic acid.
    Type: Application
    Filed: October 28, 2004
    Publication date: July 14, 2005
    Inventors: Gang Chen, Jason Crawford, Renato Skerlj
  • Patent number: 6864265
    Abstract: Compounds that bind to chemokine receptors such as CXCR4 and CCR5 demonstrate protective effects against infection of cells by human immunodeficiency virus are disclosed. These compounds contain a tertiary amine[[s]] linked to a core nitrogen via an aromatic or heteroaromatic moiety.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: March 8, 2005
    Assignee: AnorMED, Inc.
    Inventors: Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. Mceachern, Bern Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis, Rosaria Maria Di Fluri