Abstract: Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-?4?7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-?4?7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-?4?7 antibody in vivo.

Abstract: Antibody formulations are described comprising a mixture of an anti-?4?7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-?4?7 antibody in vivo.

Abstract: Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-?4?7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-?4?7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-?4?7 antibody in vivo.

Abstract: A drive module assembly includes a housing defining a housing interior for containing a lubricant. The housing interior is further defined as a first housing interior and a second housing interior. The drive module assembly also includes a first input shaft configured to receive rotational torque from a first power source, a first gear train rotatably coupled to the first input shaft, a first output shaft rotatably coupled to the first gear train, a second input shaft configured to receive rotational torque from a second power source, a second gear train disposed rotatably coupled to the second input shaft, and a second output shaft rotatably coupled to the second gear train. The first housing interior and the second housing interior are fluidly separate from one another.

Abstract: In an embodiment, a battery connector includes: power terminals configured to be coupled to a load having an input capacitance; power pins electrically coupled to the power terminals; a charge pin, the charge pin being longer than each of the power pins; and an antispark circuit electrically interposed between the charge pin and the power terminals, the antispark circuit including: a dissipation circuit configured to charge the input capacitance of the load in response to a battery being coupled to the charge pin; and a delay circuit configured to delay charging of the input capacitance of the load for a predetermined duration after the battery is coupled to the charge pin.

Abstract: A facility for constructing a display module in connection with a web page is described. The facility obtains content associated with the web page and uses the obtained content to generate a query used to select an image. The facility then generates the display module that incorporates the selected image.

Abstract: An electric submersible pump (ESP) assembly that includes an electric motor with a splined drive shaft with drive shaft teeth, an ESP mechanically coupled to the electric motor that includes a splined ESP shaft with ESP shaft teeth, and a downhole component mechanically coupled to the electric motor that includes a splined component shaft with component shaft teeth. Splined couplings each include a central axis and grooves through the coupling with groove sidewalls sized to receive the shaft teeth. The grooves are angled relative to the central axis to form a space on either side of each tooth in each groove for at least a portion of the overlapped length of the tooth within the groove. Each coupling is engageable with the teeth of two of the drive shaft, the pump shaft, or the component shaft to mechanically couple the electric motor, the ESP, and the downhole component.

Abstract: A downhole gas separator and pump assembly. The downhole gas separator and pump assembly comprises a drive shaft; a first fluid mover having an inlet and an outlet; a separation chamber located downstream of the first fluid mover and fluidically coupled to the outlet of the first fluid mover; a gas flow path and liquid flow path separator located downstream of the separation chamber, having an inlet fluidically coupled to the separation chamber, having a gas phase discharge port open to an exterior of the assembly, and having a liquid phase discharge port; and a second fluid mover mechanically coupled to the drive shaft, located downstream of the first gas flow path and liquid flow path separator, and having an inlet fluidically coupled to the fluid phase discharge port of the first gas flow path and liquid flow path separator.

Abstract: A downhole gas separator assembly. The gas separator comprises a drive shaft; a first fluid mover mechanically coupled to the drive shaft having a fluid inlet and a fluid outlet; a fluid reservoir concentrically disposed around the drive shaft and located downstream of the first fluid mover, wherein an inside surface of the fluid reservoir and an outside surface of the drive shaft define a first annulus that is fluidically coupled to the fluid outlet of the first fluid mover; a second fluid mover having a fluid inlet and a fluid outlet, wherein the second fluid mover is located downstream of the fluid reservoir, and wherein the fluid inlet of the second fluid mover is fluidically coupled to the first annulus; and a gas flow path and liquid flow path separator having a gas phase discharge port open to an exterior of the assembly and a liquid phase discharge port.

Abstract: In some embodiments, a method for controlling fluid flow through a downhole pump system in a borehole includes moving, via a downhole pump residing below a tubular in the borehole, a first fluid through the tubular, wherein the first fluid includes a compressible fluid. The method may further include increasing an intake pressure of the downhole pump while the first fluid is moving via a control valve system comprising a throttling valve.

Abstract: A downhole gas separator assembly. The gas separator comprises a drive shaft; a first fluid mover mechanically coupled to the drive shaft having a fluid inlet and a fluid outlet; a fluid reservoir concentrically disposed around the drive shaft and located downstream of the first fluid mover, wherein an inside surface of the fluid reservoir and an outside surface of the drive shaft define a first annulus that is fluidically coupled to the fluid outlet of the first fluid mover; a second fluid mover having a fluid inlet and a fluid outlet, wherein the second fluid mover is located downstream of the fluid reservoir, and wherein the fluid inlet of the second fluid mover is fluidically coupled to the first annulus; and a gas flow path and liquid flow path separator having a gas phase discharge port open to an exterior of the assembly and a liquid phase discharge port.

Abstract: In some embodiments, a method for controlling fluid flow through a downhole pump system in a borehole includes moving, via a downhole pump residing below a tubular in the borehole, a first fluid through the tubular, wherein the first fluid includes a compressible fluid. The method may further include increasing an intake pressure of the downhole pump while the first fluid is moving via a control valve system comprising a throttling valve.

Abstract: In an embodiment, a battery connector includes: power terminals configured to be coupled to a load having an input capacitance; power pins electrically coupled to the power terminals; a charge pin, the charge pin being longer than each of the power pins; and an antispark circuit electrically interposed between the charge pin and the power terminals, the antispark circuit including: a dissipation circuit configured to charge the input capacitance of the load in response to a battery being coupled to the charge pin; and a delay circuit configured to delay charging of the input capacitance of the load for a predetermined duration after the battery is coupled to the charge pin.

Abstract: A coupling includes an inner surface configured to receive a shaft of an electric submersible pump system through the inner surface. The coupling also includes an outer surface having a torsional undercut into the coupling, where the torsional undercut is configured to induce a failure of the coupling prior to a failure of the shaft.

Abstract: In an embodiment, a battery connector includes: power terminals configured to be coupled to a load having an input capacitance; power pins electrically coupled to the power terminals; a charge pin, the charge pin being longer than each of the power pins; and an antispark circuit electrically interposed between the charge pin and the power terminals, the antispark circuit including: a dissipation circuit configured to charge the input capacitance of the load in response to a battery being coupled to the charge pin; and a delay circuit configured to delay charging of the input capacitance of the load for a predetermined duration after the battery is coupled to the charge pin.

Abstract: Antibody formulations are described comprising a mixture of an anti-?4?7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-?4?7 antibody in vivo.

Abstract: Modular shelter systems are described herein. In one aspect, the modular shelter system includes an endcap positioned at a first end of the modular shelter system. The endcap includes a first support arch; and an endcap frame. The modular shelter system also includes a second support arch positioned at a second end of the modular shelter system. The modular shelter system also includes at least one section assembly disposed between the first support arch and the second support arch. The section assembly includes a plurality of purlins oriented along a longitudinal axis of the modular shelter system.

Abstract: A system can determine by which path/tunnel an Internet destination can be best reached for a user with an IP address from a static BGP range. The system looks up the destination address in an egress map. This map can either specify a tunnel that should be used for encapsulation for static BGP, or (when tunnel is not present) cause the system to send out unencapsulated traffic, in which the traffic follows normal BGP routing on a border network.

Abstract: A downhole gas separator and pump assembly. The downhole gas separator and pump assembly comprises a drive shaft; a first fluid mover having an inlet and an outlet; a separation chamber located downstream of the first fluid mover and fluidically coupled to the outlet of the first fluid mover; a gas flow path and liquid flow path separator located downstream of the separation chamber, having an inlet fluidically coupled to the separation chamber, having a gas phase discharge port open to an exterior of the assembly, and having a liquid phase discharge port; and a second fluid mover mechanically coupled to the drive shaft, located downstream of the first gas flow path and liquid flow path separator, and having an inlet fluidically coupled to the fluid phase discharge port of the first gas flow path and liquid flow path separator.

Abstract: An electric submersible pump (ESP) assembly that includes an electric motor with a splined drive shaft with drive shaft teeth, an ESP mechanically coupled to the electric motor that includes a splined ESP shaft with ESP shaft teeth, and a downhole component mechanically coupled to the electric motor that includes a splined component shaft with component shaft teeth. Splined couplings each include a central axis and grooves through the coupling with groove sidewalls sized to receive the shaft teeth. The grooves are angled relative to the central axis to form a space on either side of each tooth in each groove for at least a portion of the overlapped length of the tooth within the groove. Each coupling is engageable with the teeth of two of the drive shaft, the pump shaft, or the component shaft to mechanically couple the electric motor, the ESP, and the downhole component.