Abstract: A method, system and computer program product for index maintenance in a computer system comprising a plurality of nodes, a database, and an index to the database. In one embodiment, the method comprises, for a defined period of time, building a snapshot of selected change requests received by the nodes to change the database. After this defined period of time, a selection is made, based on specified criteria, whether to rebuild a new index to the database, or to add entries to a current index. When the selection is to rebuild a new index, the new index is rebuilt based on data in the database and in the change requests in the snapshot. When the selection is to add entries to a current index, entries are added to the current index based on data in the database and in the change requests in the snapshot.

Abstract: The present invention is directed to compounds related to precolibactin pharmaceutical compositions based upon these compounds and methods of synthesis which are employed to provide intermediates and final compounds, which are principally alkylating agents and anticancer compounds. The chemical synthetic approach disclosed facilitates the synthesis of numerous precolibactin analogs which can be used in the treatment of cancer.

Abstract: Provided herein are systems, methods and computer readable media for programmatically generating and/or revising promotion offers for a merchant based on one or more merchant self-service indicators. In providing such functionality, the system can be configured to, for example, facilitate registration and verification of merchant identities, determine promotion content and parameters based on merchant self-service indicators, and monitor and analyze promotion offers for merchants with similar merchant self-service indicators. The system may determine the relative successfulness of a promotion offer for a merchant and/or category of merchant. In some embodiments, the system may be further configured to revise the promotion offer programmatically and/or upon receiving the merchant's approval of the programmatically generated proposed edits to the promotion offer.

Abstract: Systems and related methods providing for online ordering of menu items from a merchant are discussed herein. Circuitry may be configured to generate an online menu based on menu information stored in a menu database. The menu information may be also configured to facilitate point-of-sale functionality at the merchant, such as by a point-of-sale device. The online menu may be provided to a consumer device. An online order may be received from the consumer device. The circuitry may be configured to process the online order, such as by facilitating a reservation, order preparation, and payment.

Abstract: A method, system and computer program product for index maintenance in a computer system comprising a plurality of nodes, a database, and an index to the database. In one embodiment, the method comprises, for a defined period of time, building a snapshot of selected change requests received by the nodes to change the database. After this defined period of time, a selection is made, based on specified criteria, whether to rebuild a new index to the database, or to add entries to a current index. When the selection is to rebuild a new index, the new index is rebuilt based on data in the database and in the change requests in the snapshot. When the selection is to add entries to a current index, entries are added to the current index based on data in the database and in the change requests in the snapshot.

Abstract: A meeting summarization method, system, and computer program product, include recording meeting audio of a meeting, capturing notes including a time stamp from each of a plurality of users associated with the meeting, synchronizing the recorded meeting audio of the meeting and each of the notes of each of the plurality of users based on a correlation between the time stamp, and analyzing the synchronized meeting audio and notes to determine highlights of the meeting based on a co-occurrence of notes between the plurality of users.

Abstract: A meeting summarization method, system, and computer program product, include capturing notes of a user including a time stamp from the user associated with a meeting, synchronizing an agenda of the meeting and the notes of the user based on a correlation between a time stamp of a topic on the agenda and a time stamp of the notes of the user, and analyzing the synchronized topic and the notes to determine highlights of the meeting based on a co-occurrence of the time stamp of the notes of the user and the time stamp of the topic on the agenda.

Abstract: A method, system and computer program product for index maintenance in a computer system comprising a plurality of nodes, a database, and an index to the database. In one embodiment, the method comprises, for a defined period of time, building a snapshot of selected change requests received by the nodes to change the database. After this defined period of time, a selection is made, based on specified criteria, whether to rebuild a new index to the database, or to add entries to a current index. When the selection is to rebuild a new index, the new index is rebuilt based on data in the database and in the change requests in the snapshot. When the selection is to add entries to a current index, entries are added to the current index based on data in the database and in the change requests in the snapshot.

Abstract: Provided herein are systems, methods and computer readable media for programmatically generating and/or revising promotion offers for a merchant based on one or more merchant self-service indicators. In providing such functionality, the system can be configured to, for example, facilitate registration and verification of merchant identities, determine promotion content and parameters based on merchant self-service indicators, and monitor and analyze promotion offers for merchants with similar merchant self-service indicators. The system may determine the relative successfulness of a promotion offer for a merchant and/or category of merchant. In some embodiments, the system may be further configured to revise the promotion offer programmatically and/or upon receiving the merchant's approval of the programmatically generated proposed edits to the promotion offer.

Abstract: A meeting summarization method, system, and computer program product, include recording meeting audio of a meeting, capturing notes including a time stamp from each of a plurality of users associated with the meeting, synchronizing the recorded meeting audio of the meeting and each of the notes of each of the plurality of users based on a correlation between the time stamp, and analyzing the synchronized meeting audio and notes to determine highlights of the meeting based on a co-occurrence of notes between the plurality of users.

Abstract: A meeting summarization method, system, and computer program product, include recording meeting audio of a meeting, capturing notes including a time stamp from each of a plurality of users associated with the meeting, synchronizing the recorded meeting audio of the meeting and each of the notes of each of the plurality of users based on a correlation between the time stamp, and analyzing the synchronized meeting audio and notes to determine highlights of the meeting based on a co-occurrence of notes between the plurality of users.

Abstract: A method, system and computer program product for index maintenance in a computer system comprising a plurality of nodes, a database, and an index to the database. In one embodiment, the method comprises, for a defined period of time, building a snapshot of selected change requests received by the nodes to change the database. After this defined period of time, a selection is made, based on specified criteria, whether to rebuild a new index to the database, or to add entries to a current index. When the selection is to rebuild a new index, the new index is rebuilt based on data in the database and in the change requests in the snapshot. When the selection is to add entries to a current index, entries are added to the current index based on data in the database and in the change requests in the snapshot.

Abstract: The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HW).

Abstract: A fiber optic connector panel fits within a telecommunications fiber optic distribution cabinet and terminates and protects outside plant cables. A support panel is pivotally mounted into a telecommunications fiber optic distribution cabinet. A first cylindrically configured cable storage member is supported by the support panel and configured to store any slack fiber optic pigtails. A second cable storage member is supported by the support panel and configured to store any slack outside plant cable and jumpers. A fiber optic connector is supported by the support panel and configured to connect fiber optic pigtails and fiber optic jumpers. A splice storage member is supported by the support panel and configured to store fiber optic cable splices of the fiber optic pigtails and outside plant cable and jumpers of the fiber optic pigtails and outside plant cable and jumpers.

Abstract: Compounds which modulate chemokine receptor activities are disclosed. These compounds are preferably tertiary amines comprising tetrahydroquinoline and benzimidazole.

Abstract: Heterocyclic compounds that bind chemokine receptors and inhibit the binding of their natural ligands are disclosed. The invention compounds are protective against infection by HIV and exert effects characteristic of antagonists to the CXCR4 receptor.

Abstract: Heterocyclic compounds that bind chemokine receptors and inhibit the binding of their natural ligands are disclosed. The invention compounds are protective against infection by HIV and exert effects characteristic of antagonists to the CXCR4 receptor.

Abstract: Methods for preparing 2,6-diaryl piperidine derivatives are described. More particularly, 2,6-diaryl piperidines having formula 1-4 are prepared by cyclocondensation of an aryl or heteroaryl aldehyde with 1,3-acetonedicarboxylic acid.

Abstract: Tertiary amine compounds that bind chemokine receptors such as CXCR4 and CCR5 are disclosed.

Abstract: Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.