Patents by Inventor Jason P. Schrum

Jason P. Schrum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS
    Publication number: 20130259923
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: March 9, 2013
    Publication date: October 3, 2013
    Applicant: MODERNA THERAPEUTICS
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Sayda M. Elbashir, Matthias John, Atanu Roy, Susan Whoriskey, Kristy M. Wood, Paul Hatala, Jason P. Schrum, Kenechi Ejebe, Jeff Lynn Ellsworth, Justin Guild
  • MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE
    Publication number: 20130259924
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: March 9, 2013
    Publication date: October 3, 2013
    Applicant: MODERNA THERAPEUTICS
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Sayda M. Elbashir, Matthias John, Atanu Roy, Susan Whoriskey, Kristy M. Wood, Paul Hatala, Jason P. Schrum, Kenechi Ejebe, Jeff Lynn Ellsworth, Justin Guild
  • MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF G-CSF
    Publication number: 20130253043
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Application
    Filed: May 18, 2013
    Publication date: September 26, 2013
    Applicant: Moderna Therapeutics
    Inventors: Antonin de Fougerolles, Kristy M. Wood, Sayda M. Elbashir, Jason P. Schrum
  • METHOD FOR PRODUCING A PROTEIN OF INTEREST IN A PRIMATE
    Publication number: 20130245104
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Application
    Filed: May 21, 2013
    Publication date: September 19, 2013
    Applicant: Moderna Therapeutics
    Inventors: Antonin de Fougerolles, Kristy M. Wood, Sayda M. Elbashir, Jason P. Schrum
  • METHOD OF PRODUCING ANTIBODIES
    Publication number: 20130244282
    Abstract: Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful for production of proteins.
    Type: Application
    Filed: May 18, 2013
    Publication date: September 19, 2013
    Applicant: Moderna Therapeutics
    Inventors: Jason P. Schrum, Kenechi Ejebe, Sayda M. Elbashir
  • DLIN-KC2-DMA LIPID NANOPARTICLE DELIVERY OF MODIFIED POLYNUCLEOTIDES
    Publication number: 20130245105
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Application
    Filed: May 21, 2013
    Publication date: September 19, 2013
    Applicant: Moderna Therapeutics
    Inventors: Antonin de Fougerolles, Kristy M. Wood, Sayda M. Elbashir, Jason P. Schrum
  • MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF FACTOR IX
    Publication number: 20130245103
    Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
    Type: Application
    Filed: May 18, 2013
    Publication date: September 19, 2013
    Applicant: Moderna Therapeutics
    Inventors: Antonin de Fougerolles, Sayda M. Elbashir, Jason P. Schrum
  • MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF
    Publication number: 20130102034
    Abstract: The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using thereof.
    Type: Application
    Filed: May 25, 2012
    Publication date: April 25, 2013
    Inventor: Jason P. Schrum
  • DELIVERY AND FORMULATION OF ENGINEERED NUCLEIC ACIDS
    Publication number: 20120251618
    Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
    Type: Application
    Filed: April 2, 2012
    Publication date: October 4, 2012
    Applicant: modeRNA Therapeutics
    Inventors: Jason P. Schrum, Noubar B. Afeyan, Gregory J. Sieczkiewicz, Stephane Bancel, Antonin de Fougerolles, Sayda M. Elbashir