Abstract: An antimicrobial composition comprising: (1) povidone iodine (PVP-I) in a concentration of 5 to 10% w/w of the composition; and (2) carboxymethylcellulose (CMC) in a concentration of 0.1 to 5 % w/w of the composition.

Abstract: An antiseptic composition for penetrating and treating the dermis and/or pilosebaceous follicle of a mammal, said antiseptic composing comprising: (a) a sebostatic agent for reducing sebum production to prevent clogging of skin pores; (b) a barrier-forming emollient for forming a protective barrier film to aid said dermis in maintaining moisture and to shield said dermis from the environment; and (c) an antiseptic agent.

Abstract: A surgical instrument wrap having at least one or a plurality of fibrous layers that cooperate with at least one agent or dye layer that is generally not visible until the at least one or plurality of fibrous layers is damaged or disrupted. The at least one diffusible agent or dye layer diffuses or wicks into the disrupted or damaged area. A fluorescent dye, a reactive dye, a conjugant dye or an absorption wavelength of approximately 200-400 nanometers in one embodiment and an emission wavelength in the visible spectrum so that when the surgical wrap is damage or disrupted and then exposed to, for example, a fluorescent or ultraviolet light source, the agent or dye fluoresces to provide an indication to the user that damage to the wrap has occurred. The user can presume that the items or instruments in the surgical tray may be contaminated.

Abstract: A method of using a Defined Swab for genetic identification of microbes, said method comprising contacting said swab with a target to absorb a sample of said target; extracting said sample from said swab; and microbiologically testing said sample to identify said microbe.

Abstract: The present disclosure relates to compositions, methods and test devices for determining the presence of active leukocyte cells, for example, by using novel LE and/or HNE substrates in an electrochemical assay.

Abstract: This invention relates to the detection and quantification of D-dimer levels in a sample derived from a patient having or suspected of having periprosthetic joint infection (PJI) and subsequent diagnosis of PJI.

Abstract: The present disclosure relates to compositions, methods and test devices for determining the presence of active leukocyte cells, for example, by using novel LE and/or HNE substrates in an electrochemical assay.

Abstract: The present disclosure relates to compositions, methods and test devices for determining the presence of active leukocyte cells, for example, by using novel LE and/or HNE substrates in an electrochemical assay.

Abstract: A knee joint implant is capable of resolving issues of conventional cementless or uncemented implants. The knee joint implant improves fixing force of the implant in a vertical direction and provides improved initial fixation for the implant.

Abstract: This invention relates to methods for administering an effective amount of a dietary or nutritional supplement composition that effectively changes the levels of biomarkers in the synovium of a joint and resulting in decreased pain and ultimately better outcomes for subjects. The formulation comprises an effective amount of the following: Boswellia; Vitamin C; Ginger; Turmeric; Vitamin D3; and Rutin. In a preferred embodiment of the composition of the invention, the composition is substantially free of omega-3 fatty acids.

Abstract: A ready-to-use, gamma-ray sterilized, surgical antiseptic composition comprising an initial non-toxic concentration of povidone-iodine above a minimum effective concentration of available iodine, iodide in sufficient quantity to provide donor iodine upon gamma irradiation to stabilize said povidone-iodine and maintain said minimum effective concentration of available iodine, and a buffered saline solution.

Abstract: Disclosed is a resection guide, a trial knee joint implant, and a surgical instrument for knee arthroplasty. The resection guide, the trial knee joint implant, and the surgical instrument enable implantation of an implant that provides improved vertical fixing force and initial fixing force as compared with an existing cementless or uncemented implant.

Abstract: An implant for an artificial hip joint and, more specifically, a dual mobility acetabular cup assembly for an artificial hip joint is configured to have improved locking mechanism between a liner and a shell and improved resistance to micromotion and to guide the liner into the shell with proper orientation by providing stable liner-shell fastening structure to the acetabular cup assembly.

Abstract: This invention relates to the detection and quantification of D-dimer levels in a sample derived from a patient having or suspected of having periprosthetic joint infection (PJI) and subsequent diagnosis of PJI.

Abstract: A set of surgical instruments for an artificial hip joint implant and, more specifically, a set of improved surgical instruments, can be used in direct anterior approach hip replacement surgery and are capable of minimizing damage, such as muscle damage, which may arise during surgery, by resolving problems that existing surgical instruments possess.

Abstract: This invention relates to methods for administering an effective amount of a dietary or nutritional supplement composition that effectively changes the levels of biomarkers in the synovium of a joint and resulting in decreased pain and ultimately better outcomes for subjects. The formulation comprises an effective amount of the following: Boswellia; Vitamin C; Ginger; Turmeric; Vitamin D3; and Rutin. In a preferred embodiment of the composition of the invention, the composition is substantially free of omega-3 fatty acids.

Abstract: The present disclosure relates to compositions, methods and test devices for determining the presence of active leukocyte cells, for example, by using novel LE and/or FINE substrates in an electrochemical assay.

Abstract: A functionalized tissue having covalently bound antibiotics and methods for producing the functionalized tissue having bound antibiotics comprising; providing a tissue having a sufficient number of primary amine groups on the tissue; coupling and deprotecting one or more F-moc AEEA linkers using HATU chemistry to the primary amine groups; and coupling an antibiotic to said AEEA linkers using HATU chemistry.

Abstract: Disclosed is a resection guide, a trial knee joint implant, and a surgical instrument for knee arthroplasty. The resection guide, the trial knee joint implant, and the surgical instrument enable implantation of an implant that provides improved vertical fixing force and initial fixing force as compared with an existing cementless or uncemented implant.