Abstract: Disclosed is a resection guide, a trial knee joint implant, and a surgical instrument for knee arthroplasty. The resection guide, the trial knee joint implant, and the surgical instrument enable implantation of an implant that provides improved vertical fixing force and initial fixing force as compared with an existing cementless or uncemented implant.

Abstract: A set of surgical instruments for an artificial hip joint implant and, more specifically, a set of improved surgical instruments, can be used in direct anterior approach hip replacement surgery and are capable of minimizing damage, such as muscle damage, which may arise during surgery, by resolving problems that existing surgical instruments possess.

Abstract: An implant for an artificial hip joint and, more specifically, a dual mobility acetabular cup assembly for an artificial hip joint is configured to have improved locking mechanism between a liner and a shell and improved resistance to micromotion and to guide the liner into the shell with proper orientation by providing stable liner-shell fastening structure to the acetabular cup assembly.

Abstract: Methods and systems for selecting an appropriate prosthesis for a prospective implant recipient are discussed. For example, a method for selecting an appropriate prosthesis can include, accessing anatomical image data, receiving an indication of a plurality of landmark locations within the image data, constructing a femoral canal axial indication within the image data, producing a plurality of lateral anatomic structural measurements, and selecting the appropriate prosthesis to fit the prospective implant recipient. The anatomical image data can include sufficient detail to allow measurement of internal and external geometry of a proximal femur. The plurality of lateral anatomic structural measurements can include measurements along, and perpendicular to, the femoral canal axial indication that run along a femoral canal within the anatomical image data. The prosthesis can be selected based, at least in part, on the plurality of lateral anatomic structural measurements.

Abstract: A spacer comprised of individual components as joint replacement in the arthroplasty of shoulder, knee, and hip for the temporary surgical care of infections in the joint. The problems addressed by the invention are those of avoiding an adhesion of the bone to the spacer and a release of wear products, achieving that the patient does substantially not experience any mobility restriction, and keeping the wear and tear of the spacer as little as possible. These problems are solved in that at least one component of the spacer is made of a ceramic material, of a plurality of ceramic materials, or of a non-ceramic material having a ceramic coating.

Abstract: Diagnostic assays and related systems, test samples and methods are described for detection of infection following implantation of a prosthetic material or device on and/or into bones and joints. A combination of at least two biomarkers is used, one specific to the pathogenic microbe and the other specific to the destruction of peri-implant tissues. The biomarkers are detectable in the peripheral blood, urine, fluid or tissue samples drawn from a peri-implant environment. They can also be detected with a blood or urine test that is highly sensitive for detecting specific structural microbial molecules and peri-implant tissue components.

Abstract: Methods and systems for selecting an appropriate prosthesis for a prospective implant recipient are discussed. For example, a method for selecting an appropriate prosthesis can include, accessing anatomical image data, receiving an indication of a plurality of landmark locations within the image data, constructing a femoral canal axial indication within the image data, producing a plurality of lateral anatomic structural measurements, and selecting the appropriate prosthesis to fit the prospective implant recipient. The anatomical image data can include sufficient detail to allow measurement of internal and external geometry of a proximal femur. The plurality of lateral anatomic structural measurements can include measurements along, and perpendicular to, the femoral canal axial indication that run along a femoral canal within the anatomical image data. The prosthesis can be selected based, at least in part, on the plurality of lateral anatomic structural measurements.

Abstract: The present invention is directed to implants that include therapeutic molecules bonded to their surfaces. The therapeutic molecules interact with cells that are adjacent, near, or adhering to the implant. The covalently-bonded therapeutic molecules may be released from the implant surface by changes in pH or enzymes characteristic of cells adjacent to the implant. Preferably the covalently-bonded agents include an antibiotics that are released from the implant surface by bacteria and in this way ensures that the antibiotic is released at sites on the implant that would serve as centers for both bacterial colonization and biofilm formation.