Abstract: During text-to-speech processing, a speech model creates synthesized speech that corresponds to input data. The speech model may include an encoder for encoding the input data into a context vector and a decoder for decoding the context vector into spectrogram data. The speech model may further include a voice decoder that receives vocal characteristic data representing a desired vocal characteristic of synthesized speech. The voice decoder may process the vocal characteristic data to determine configuration data, such as weights, for use by the speech decoder.

Abstract: Tempered xylitol coatings and methods for applying the same are disclosed. A gum coating device coats a gum core with a first syrup to form a first coating, wherein the first syrup comprises xylitol, a first coating impurity, and a binder. The first syrup does not include a coloring agent and the first coating impurity is selected to slow the crystallization of xylitol. The gum coating device coats an outer surface of the first coating with a second syrup to form a second coating. The second syrup comprises xylitol, a second coating impurity, a binder, and a coloring agent. The second coating impurity is selected to slow the crystallization of xylitol. The gum coating device tempers the gum core after at least a first layer of the first coating is applied and before a last layer of the second coating is applied.

Abstract: Disclosed herein are methods and processes of preparing vadadustat and pharmaceutically acceptable salts thereof, and intermediates of formula (I) and their salts useful for the synthesis of vadadustat.

Abstract: Various electric scooter docking stations are described herein. In some embodiments, the docking stations facilitate the collection, movement, and/or storage of electric scooters in a compact, elegant, and efficient configuration. For example, the docking stations can be configured to take advantage of the unique shape of a scooter, providing the storage and positioning of many scooters in a compact area. Also, the docking stations can be simple structures that facilitate the self-powered movement of electric scooters within a station.

Abstract: The present invention relates to nanoparticles for encapsulating compounds, the preparation and uses thereof, comprising a casein matrix, a basic amino acid and a metal selected from a divalent metal, a trivalent metal and combinations thereof. Said nanoparticles can encapsulate a water soluble or fat soluble biologically active compound. The invention is applicable in the food, pharmaceutical and cosmetic sectors and in the nanotechnology sector.

Abstract: A read network topology for a matrix output device with a number of outputs determined by cross-joining “m” rows and “n” columns comprises a basic filtering block replicated for all the outputs and separately assigned to each of the outputs; each filtering block contains two filtering circuits that have a common input connection to the assigned matrix output and that provide two separate symmetrical and filtered outputs; all the row outputs (i) from the same row “i” but from different columns are interconnected to an input of an amplifier linked to row “i”, and all the column outputs (j) from the same column “j” but from different rows are connected together to an input of an amplifier linked to column “j”, the complete topology appearing when “i” and “j” are expanded in the respective intervals thereof.

Abstract: The invention is relate with a pharmaceutical composition comprising peptide type APL called identified as SEQ ID No. 1, sodium acetate buffer at pH 3.9-4.7; and at least one stabilizing sugar selected from sucrose or trehalose. This pharmaceutical composition is useful for manufacture of a medicament for treating inflammatory diseases related to an increase of neutrophils or citrullination of proteins. These inflammatory diseases include rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), ankylosing spondylitis (AS), Alzheimer's disease, and hepatic and pulmonary fibrosis. The invention also discloses a method for the treatment of these diseases, through effective therapeutic administration of the pharmaceutical composition of APL-type peptide.

Abstract: Methods and systems for planning and forming incisions in a cornea, lens capsule, and/or crystalline lens nucleus are disclosed. A method includes measuring spatial dispositions, relative to a laser surgery system, of at least portions of the corneal anterior and posterior surfaces. A spatial disposition of an incision of the cornea is generated based at least in part on the measured corneal anterior and posterior spatial dispositions and at least one corneal incision parameter. A composite image is displayed that includes an image representative of the measured corneal anterior and posterior surfaces and an image representing the corneal incision.

Abstract: The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication.

Abstract: A PET imaging device for observing a brain includes a hollow three-dimensional structure with a shape capable of housing a head. The PET imaging device comprising multiple independent gamma ray detection modules that together form a structure capable of surrounding the head, said detection modules comprise continuous scintillation crystal blocks, wherein “continuous” means that the crystal blocks can be continuous in one or in two directions, each of the continuous scintillation crystal blocks has a polygonal main cross-section, and said structure is an elongated structure having a major axis in a direction corresponding to the front-nape direction and a shorter axis in a direction corresponding to a straight line joining ears on the head. The continuous scintillation crystal blocks are positioned adjacent to fit laterally in an exact manner with each other throughout their entire thickness, building a mosaic, without gaps between adjacent crystal blocks and without overlapping each other.

Abstract: The following invention discloses a method for the control of plant diseases wherein a composition comprising a compound having the structure represented by one of the formulas from I to V, is applied to the plants. It also discloses the use of said compounds, or their salts for the stimulation of the natural defense and the induction of resistance against plant diseases. Moreover, it comprises the use of said compounds of structure represented by one of the formulas from I to V for the preventive or curative treatment of said diseases. A composition for agriculture, comprising a compound having the structure represented by one of the formulas from I to V, is also part of the invention.

Abstract: A laser eye surgery system focuses light along a beam path to a focal point having a location within a lens of the eye. The refractive index of the lens is determined in response to the location. The lens comprises a surface adjacent a second material having a second refractive index. The beam path extends a distance from the surface to the focal point. The index is determined in response to the distances from the surface to the targeted focal point and from the surface to the actual focal point, which corresponds to a location of a peak intensity of an optical interference signal of the focused light within the lens. The determined refractive index is mapped to a region in the lens, and may be used to generate a gradient index profile of the lens to more accurately place laser beam pulses for incisions.

Abstract: A method for training a breast cancer screening model includes: accessing a set of thermographic images of a torso of a patient, the set of thermographic images associated with a pathology label. The method also includes, for each of the set of thermographic images: calculating an image mask defining a breast area; within the image mask, distributing a set of sampling points, the set of sampling points approximating locations of temperature sensors in a sensor mesh of a temperature sensing brassiere if the temperature sensing brassiere were worn over the torso of the patient; for each sampling point in the set of sampling points, extracting a temperature data point from the set of thermographic images to generate a temperature map; generating an input vector based on the temperature map; and inputting the input vector and the pathology label as a training example in a breast cancer screening model.

Abstract: A wound therapy system includes a dressing sealable over a wound and defining a wound space between the dressing and the wound, tubing fluidly communicable with the wound space, and a canister fluidly communicable with the tubing. The canister, the tubing, and the dressing define a sealed space that includes the wound space. The wound therapy system also includes a therapy unit coupled to the canister. The therapy unit includes a sensor configured to measure a pressure in the sealed space, a valve positioned between the sealed space and a surrounding environment and controllable between an open position and a closed position, and a control circuit. The control circuit is configured to control the valve to alternate between the open position and the closed position to allow airflow through the valve, receive measurements from the sensor, and determine a volume of the wound space based on the measurements.

Abstract: The invention relates to a PET imaging device for observing the brain, characterised by comprising a structure with a shape that is capable of accommodating a human head, having independent gamma-ray detection modules, said detection modules having continuous scintillation crystals with a polygonal main section, wherein all together the detection modules form a hollow three-dimensional structure that can surround the head, and with said three-dimensional structure being elongated and having a main axis in the direction corresponding to the forehead-nape direction and a shorter axis in the direction corresponding to the straight line joining the ears, and with the adjacent scintillation crystals fitting together laterally in a precise manner along their entire thickness, forming a mosaic-like structure, i.e. without leaving gaps and without overlapping with one another.

Abstract: Methods and systems for planning and forming incisions in a cornea, lens capsule, and/or crystalline lens nucleus are disclosed. A method includes measuring spatial dispositions, relative to a laser surgery system, of at least portions of the corneal anterior and posterior surfaces. A spatial disposition of an incision of the cornea is generated based at least in part on the measured corneal anterior and posterior spatial dispositions and at least one corneal incision parameter. A composite image is displayed that includes an image representative of the measured corneal anterior and posterior surfaces and an image representing the corneal incision.

Abstract: The present invention relates to a method for the degradation of gliadin in flour for bread making, by means of a step of mixing the flour with water, at least one step of performing enzymatic hydrolysis, at least one step of fermenting using microorganisms in controlled-pH conditions, and a step of drying to obtain a gliadin-free flour.

Abstract: A laser eye surgery system focuses light along a beam path to a focal point having a location within a lens of the eye. The refractive index of the lens is determined in response to the location. The lens comprises a surface adjacent a second material having a second refractive index. The beam path extends a distance from the surface to the focal point. The index is determined in response to the distances from the surface to the targeted focal point and from the surface to the actual focal point, which corresponds to a location of a peak intensity of an optical interference signal of the focused light within the lens. The determined refractive index is mapped to a region in the lens, and may be used to generate a gradient index profile of the lens to more accurately place laser beam pulses for incisions.

Abstract: A method of imaging an object includes obtaining an image data set from a raster scan. The image data set has a plurality of data points, each data point having an associated location and intensity; generating a reduced data set by selectively removing one or more data points from the image data set based upon an assigned probability of retaining the one or more data points in the data set, the assigned probability being a function of the intensity of a data point; generating a triangulation graph as a planar subdivision having faces that are triangles, the vertices of which are the data points and the edges of which are adjacent vertices; and segmenting the triangulated data set by finding a path with lowest cost between that vertex and every other vertex, wherein the cost is a function of the respective intensity of the vertices.

Abstract: A grease trap for separating waste from waste water that includes grey water and FOG includes a tank having a bottom and an interior volume. An inlet invert in the tank has a discharge end for discharging waste water into the tank, and an outlet invert in the tank has a drain end for removing grey water from the tank. A first baffle across the interior volume below the discharge of the inlet invert and above the drain end of the outlet invert has a hole allowing grey water to descend through the hole to a path under the first baffle to the drain end of the outlet invert. A second baffle across the interior volume above the discharge of the inlet invert has a hole allowing FOG to float through the hole in the second baffle to collect above the second baffle.