Patents by Inventor Jean-Baptiste Dumas
Jean-Baptiste Dumas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7223727Abstract: The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GSSP4 polypeptides have been identified that are believed to be beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing cholesterol levels, body mass, body fat, and for treating metabolic-related diseases and disorders. The metabolic-related diseases or disorders include, but are not limited to, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, diabetes, glucose intolerance, insulin resistance and hypertension.Type: GrantFiled: February 7, 2002Date of Patent: May 29, 2007Assignee: Serono Genetics Institute S.A.Inventors: Barbara Chicca, John Chicca, Blake Denison, Frances Yen-Potin, Bernard Bihain, Stephane Bejanin, Hiroaki Tanaka, Severin Jobert, Jean-Yves Giordano, Jean-Baptiste Dumas Milne Edwards
-
Publication number: 20070108341Abstract: The invention relates to an aircraft engine assembly (1) including an engine (6) and an engine mounting device (4), the mounting device being designed to be inserted between a wing of the aircraft and the engine, and comprising a rigid structure (8) and means of mounting the engine onto the rigid structure, the mounting means comprising a forward fastener (10) and an aft fastener (12). According to the invention, the aft fastener comprises two aft half-fasteners (12a) that will each resist at least the forces applied along a longitudinal direction (X) of the engine, and the two aft half-fasteners are arranged so that a horizontal plane (P) passing through a longitudinal axis (5) of the engine passes through each of them.Type: ApplicationFiled: June 21, 2006Publication date: May 17, 2007Applicant: Airbus FranceInventors: Lionel Diochon, Samir El Hammami, Julie Le Louvetel-Poilly, Jean-Baptiste Dumas, Nicolas Koenig
-
Publication number: 20070009941Abstract: The sequences of extended cDNAs encoding secreted proteins are disclosed. The extended cDNAs can be used to express secreted proteins or portions thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The extended cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The extended cDNAs may also be used to design expression vectors and secretion vectors.Type: ApplicationFiled: June 16, 2006Publication date: January 11, 2007Applicant: Serono Genetics Institute S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Aymeric Duclert, Lydie Bougueleret
-
Publication number: 20060286639Abstract: The sequences of cDNAs encoding secreted proteins are disclosed. The cDNAs can be used to express secreted proteins or fragments thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The cDNAs may also be used to design expression vectors and secretion vectors.Type: ApplicationFiled: June 29, 2006Publication date: December 21, 2006Applicant: SERONO GENETICS INSTITUTE S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Lydie Bougueleret, Severin Jobert, Catherine Clusel, Aymeric Duclert
-
Patent number: 7122644Abstract: The invention provides the genomic sequence of GSSP-2, GSSP-2 cDNAs and GSSP-2 polypeptides. Further the invention provides polynucleotides including biallelic markers derived from the GSSP-2 gene and from genomic regions flanking the gene. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid molecule containing sample for one or more biallelic markers of the invention. Further, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype. The invention also concerns methods and compositions for killing neoplastic cells or inhibiting neoplastic cell growth. In particular, the present invention concerns cell proliferation arresting/inhibiting and apoptosis/necrosis inducing compositions and methods for the treatment of tumors. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides.Type: GrantFiled: April 10, 2002Date of Patent: October 17, 2006Assignee: Serono Genetics Institute S.A.Inventors: Frances Yen-Potin, Blake Denison, Aymeric Duclert, Lydie Bougueleret, Catherine Clusel, Jean-Baptiste Dumas Milne Edwards, Bernard Bihain, Barbara Bour, Dana Ebbets-Reed, Luisa Salter-Cid
-
Publication number: 20060223142Abstract: The sequences of extended cDNAs encoding secreted proteins are disclosed. The extended cDNAs can be used to express secreted proteins or portions thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The extended cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The extended cDNAs may also be used to design expression vectors and secretion vectors.Type: ApplicationFiled: November 10, 2005Publication date: October 5, 2006Applicant: Serono Genetics Institute S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Aymeric Duclert, Lydie Bougueleret
-
Patent number: 7115416Abstract: The sequences of 5? ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5? ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5? ESTs. The 5? ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be obtained using the 5? ESTs. The 5? ESTs may also be used to design expression vectors and secretion vectors.Type: GrantFiled: March 3, 2004Date of Patent: October 3, 2006Assignee: Serono Genetics Institute S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Aymeric Duclert, Jean-Yves Giordano
-
Publication number: 20060189793Abstract: The invention provides the genomic sequence of GSSP-2, GSSP-2 cDNAs and GSSP-2 polypeptdes. Further the invention provides polynucleotides including biallelic markers derived from the GSSP-2 gene and from genomic regions flanking the gene. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid molecule containing sample for one or more biallelic markers of the invention. Further, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype. The invention also concerns methods and compositions for killing neoplastic cells or inhibiting neoplastic cell growth. In particular, the present invention concerns cell proliferation arresting/inhibiting and apoptosis/necrosis inducing compositions and methods for the treatment of tumors. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides.Type: ApplicationFiled: April 27, 2006Publication date: August 24, 2006Applicant: Serono Genetics Institute S.A.Inventors: Frances Yen, Blake Denison, Aymeric Duclert, Lydie Bougueleret, Catherine Clusel, Jean-Baptiste Dumas Milne-Edwards, Bernard Bihain, Barbara Bour, Dana Ebbets-Reed, Luisa Salter-Cid
-
Publication number: 20060130160Abstract: The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.Type: ApplicationFiled: August 4, 2005Publication date: June 15, 2006Applicant: Serono Genetics Institute S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Lydie Bougueleret, Severin Jobert
-
Patent number: 7060479Abstract: The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.Type: GrantFiled: June 8, 2001Date of Patent: June 13, 2006Assignee: Serono Genetics Institute, S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Lydie Bougueleret, Severin Jobert
-
Patent number: 7056680Abstract: The sequence of a cDNA encoding Claudin-50 and sequence of Claudin-50 protein are disclosed. The cDNA can be used to express the protein or portions thereof or to obtain antibodies capable of specifically binding to the secreted protein. The cDNA may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The cDNA may also be used to design expression vectors and secretion vectors.Type: GrantFiled: December 10, 2002Date of Patent: June 6, 2006Assignee: Serono Genetics Institute S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Aymeric Duclert, Lydie Bougueleret
-
Publication number: 20060053498Abstract: The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.Type: ApplicationFiled: April 18, 2001Publication date: March 9, 2006Inventors: Stephane Bejanin, Jean-Baptiste Dumas Milne Edwards, Jean-Yves Giordano, Severin Jobert, Hiroaki Tanaka
-
Publication number: 20060009633Abstract: The sequences of cDNAs encoding secreted proteins are disclosed. The cDNAs can be used to express secreted proteins or fragments thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The cDNAs may also be used to design expression vectors and secretion vectors.Type: ApplicationFiled: October 15, 2001Publication date: January 12, 2006Applicant: GENSET, S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Lydie Bougueleret, Severin Jobert, Catherine Clusel, Aymeric Duclert
-
Patent number: 6936692Abstract: The sequences of extended cDNAs encoding secreted proteins are disclosed. The extended cDNAs can be used to express secreted proteins or portions thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The extended cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The extended cDNAs may also be used to design expression vectors and secretion vectors.Type: GrantFiled: July 11, 2001Date of Patent: August 30, 2005Assignee: Genset, S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Aymeric Duclert, Lydie Bougueleret
-
Publication number: 20050106595Abstract: The sequences of 5? ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5? ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5? ESTs. The 5? ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be obtained using the 5? ESTs. The 5? ESTs may also be used to design expression vectors and secretion vectors.Type: ApplicationFiled: August 25, 2004Publication date: May 19, 2005Applicant: Genset S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Aymeric Duclert, Jean-Yves Giordano
-
Publication number: 20050106599Abstract: The sequences of extended cDNAs encoding secreted proteins are disclosed. The extended cDNAs can be used to express secreted proteins or portions thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The extended cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The extended cDNAs may also be used to design expression vectors and secretion vectors.Type: ApplicationFiled: August 30, 2004Publication date: May 19, 2005Inventors: Jean-Baptiste Dumas Edwards, Aymeric Duclert, Lydie Bougueleret
-
Publication number: 20050096458Abstract: The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.Type: ApplicationFiled: August 19, 2003Publication date: May 5, 2005Inventors: Jean-Baptiste Dumas Milne Edwards, Lydie Bougueleret, Severin Jobert
-
Publication number: 20050075285Abstract: The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GSSP4 polypeptides have been identified that are believed to be beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing cholesterol levels, body mass, body fat, and for treating metabolic-related diseases and disorders. The metabolic-related diseases or disorders envisioned to be treated by the methods of the invention include, but are not limited to: obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, diabetes, glucose intolerance, insulin resistance and hypertension.Type: ApplicationFiled: February 7, 2002Publication date: April 7, 2005Inventors: Barbara Bour, John Chicca, Blake Denison, Frances Yen-Potin, Bernard Bihain, Stephane Bejanin, Hiroaki Tanaka, Severin Jobert, Jean-Yves Giordano, Jean-Baptiste Dumas Milne Edwards
-
Publication number: 20040248780Abstract: The invention provides the genomic sequence of GSSP-2, GSSP-2 cDNAs and GSSP-2 polypeptides. Further the invention provides polynucleotides including biallelic markers derived from the GSSP-2 gene and from genomic regions flanking the gene. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid molecule containing sample for one or more biallelic markers of the invention. Further, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype. The invention also concerns methods and compositions for killing neoplastic cells or inhibiting neoplastic cell growth. In particular, the present invention concerns cell proliferation arresting/inhibiting and apoptosis/necrosis inducing compositions and methods for the treatment of tumors. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides.Type: ApplicationFiled: April 10, 2002Publication date: December 9, 2004Applicant: GENSET, S.A.Inventors: Frances Yen, Blake Denison, Aymeric Duclert, Lydie Bougueleret, Catherine Clusel, Jean-Baptiste Dumas Milne-Edwards, Bernard Bihain, Barbara Bour, Dana Ebbets-Reed, Luisa Salter-Cid
-
Patent number: 6822072Abstract: The sequences of 5′ ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5′ ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5′ ESTs. The 5′ ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be obtained using the 5′ ESTs. The 5′ ESTs may also be used to design expression vectors and secretion vectors.Type: GrantFiled: December 21, 1999Date of Patent: November 23, 2004Assignee: Genset S.A.Inventors: Jean-Baptiste Dumas Milne Edwards, Aymeric Duclert, Jean-Yves Giordano