Patents by Inventor Jean-Jacques Simon

Jean-Jacques Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11529361
    Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: December 20, 2022
    Assignee: UNION therapeutics A/S
    Inventors: Morten Otto Alexander Sommer, Rasmus Vendler Toft-Kehler, Daniel Jean Jacques Simon
  • Patent number: 11331327
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: May 17, 2022
    Assignee: UNION therapeutics A/S
    Inventors: Emilie Flora Aurore Delavenne, Daniel Jean Jacques Simon, Morten Otto Alexander Sommer, Rasmus Vendler Toft-Kehler
  • Patent number: 11324761
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: May 10, 2022
    Assignee: UNION therapeutics A/S
    Inventors: Emilie Flora Aurore Delavenne, Daniel Jean Jacques Simon, Morten Otto Alexander Sommer, Rasmus Vendler Toft-Kehler
  • Patent number: 11285164
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenesGrain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: March 29, 2022
    Assignee: UNION therapeutics A/S
    Inventors: Emilie Flora Aurore Delavenne, Daniel Jean Jacques Simon, Morten Otto Alexander Sommer, Rasmus Vendler Toft-Kehler
  • Patent number: 11283304
    Abstract: A rectenna device (400) for converting incident light to electrical energy is disclosed. The rectenna device comprises a substrate (402), a first metallic layer (404) having a predefined thickness deposited on top of the substrate, a rectifying element (405) deposited on top of the first metallic layer, a second metallic layer (408) deposited on top of said rectifying element and configured to collect electromagnetic waves of the incident light and to couple it into plasmonic waves within the rectenna device, the second metallic layer comprising an array of a plurality of metallic patches (410) spaced from each other according to a predefined spacing, each metallic patch having predefined dimensions.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: March 22, 2022
    Assignees: UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE CENTRALE DE MARSEILLE, UNIVERSITE DE TOULON
    Inventors: David Duche, Ludovic Escoubas, Ujwol Palanchoke, Jean-Jacques Simon, Teodor Silvius Balaban
  • Patent number: 11277095
    Abstract: A method for producing a multicoloured optoelectronic device is provided as well as a device produced with that method. An electrically conducting substrate including a first and second portion adjacent to the first portion is obtained. Then a first photoactive material having optical properties in a first frequency range is deposited on the first portion and a second photoactive material differing from the first photoactive material having optical properties in a second frequency range is deposited on the second portion, the first photoactive material contacting the second photoactive material, forming a photoactive layer of the multicoloured optoelectronic device.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: March 15, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ D'AIX-MARSEILLE
    Inventors: Jörg Ackermann, Sadok Ben Dkhil, Olivier Margeat, David Duché, Ludovic Escoubas, Jean-Jacques Simon, Christine Videlot-Ackermann
  • Publication number: 20210308153
    Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.
    Type: Application
    Filed: November 6, 2020
    Publication date: October 7, 2021
    Inventors: Morten Otto Alexander Sommer, Ramus Vendler Toft-Kehler, Daniel Jean Jacques Simon
  • Patent number: 10857164
    Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: December 8, 2020
    Assignee: UNION therapeutics A/S
    Inventors: Morten Otto Alexander Sommer, Ramus Vendler Toft-Kehler, Daniel Jean Jacques Simon
  • Publication number: 20200358321
    Abstract: A rectenna device (400) for converting incident light to electrical energy is disclosed. The rectenna device comprises a substrate (402), a first metallic layer (404) having a predefined thickness deposited on top of the substrate, a rectifying element (405) deposited on top of the first metallic layer, a second metallic layer (408) deposited on top of said rectifying element and configured to collect electromagnetic waves of the incident light and to couple it into plasmonic waves within the rectenna device, the second metallic layer comprising an array of a plurality of metallic patches (410) spaced from each other according to a predefined spacing, each metallic patch having predefined dimensions.
    Type: Application
    Filed: November 28, 2018
    Publication date: November 12, 2020
    Inventors: David DUCHE, Ludovic ESCOUBAS, Ujwol PALANCHOKE, Jean-Jacques SIMON, Teodor Silvius BALABAN
  • Publication number: 20200306271
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Application
    Filed: June 12, 2020
    Publication date: October 1, 2020
    Inventors: Emilie Flora Aurore DELAVENNE, Daniel Jean Jacques SIMON, Morten Otto Alexander SOMMER, Rasmus Vendler TOFT-KEHLER
  • Publication number: 20200306269
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosam-ide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenesGrain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appear-ance of resistant mutants compared to commonly used topical antibiotics.
    Type: Application
    Filed: June 12, 2020
    Publication date: October 1, 2020
    Inventors: Emilie Flora Aurore DELAVENNE, Daniel Jean Jacques SIMON, Morten Otto Alexander SOMMER, Rasmus Vendler TOFT-KEHLER
  • Publication number: 20200306270
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Application
    Filed: June 12, 2020
    Publication date: October 1, 2020
    Inventors: Emilie Flora Aurore DELAVENNE, Daniel Jean Jacques SIMON, Morten Otto Alexander SOMMER, Rasmus Vendler TOFT-KEHLER
  • Patent number: 10758553
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: September 1, 2020
    Assignee: UNION therapeutics A/S
    Inventors: Emilie Flora Aurore Delavenne, Daniel Jean Jacques Simon, Morten Otto Alexander Sommer, Rasmus Vendler Toft-Kehler
  • Publication number: 20200093839
    Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.
    Type: Application
    Filed: October 1, 2019
    Publication date: March 26, 2020
    Inventors: Morten Otto Alexander Sommer, Ramus Vendler Toft-Kehler, Daniel Jean Jacques Simon
  • Publication number: 20190393836
    Abstract: A method for producing a multicoloured optoelectronic device is provided as well as a device produced with that method. An electrically conducting substrate including a first and second portion adjacent to the first portion is obtained. Then a first photoactive material having optical properties in a first frequency range is deposited on the first portion and a second photoactive material differing from the first photoactive material having optical properties in a second frequency range is deposited on the second portion, the first photoactive material contacting the second photoactive material, forming a photoactive layer of the multicoloured optoelectronic device.
    Type: Application
    Filed: February 23, 2018
    Publication date: December 26, 2019
    Inventors: Jörg ACKERMANN, Sadok BEN DKHIL, Olivier MARGEAT, David DUCHÉ, Ludovic ESCOUBAS, Jean-Jacques SIMON, Christine VIDELOT-ACKERMANN
  • Patent number: 10463680
    Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhea and C. difficile associated colitis.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: November 5, 2019
    Assignee: UNION therapeutics A/S
    Inventors: Morten Otto Alexander Sommer, Rasmus Vendler Toft-Kehler, Daniel Jean Jacques Simon
  • Publication number: 20190099433
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Application
    Filed: September 7, 2018
    Publication date: April 4, 2019
    Inventors: Emilie Flora Aurore DELAVENNE, Daniel Jean Jacques SIMON, Morten Otto Alexander SOMMER, Rasmus Vendler TOFT-KEHLER
  • Publication number: 20180207179
    Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.
    Type: Application
    Filed: May 27, 2016
    Publication date: July 26, 2018
    Applicant: ANTIBIOTX A/S
    Inventors: Morten Otto Alexander SOMMER, Rasmus Vendler TOFT-KEHLER, Daniel Jean Jacques SIMON
  • Patent number: 9949988
    Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Gram positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: April 24, 2018
    Assignee: AntibioTx A/S
    Inventors: Emilie Flora Aurore Delavenne, Daniel Jean Jacques Simon, Morten Otto Alexander Sommer, Rasmus Vendler Toft-Kehler
  • Patent number: 9948174
    Abstract: The protection device for providing protection against short-circuits upstream from an electrical power supply module having an inlet filter with at least one capacitor and an inductor and having a converter with components associated with a plurality of freewheel diodes includes at least one auxiliary winding and a dissipator element associated with the inlet filter, thereby making it possible to provide an inlet filter of small size without over dimensioning the freewheel diodes.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: April 17, 2018
    Assignee: Safran Electrical & Power
    Inventors: Jean-Jacques Simon, Nicolas Dheilly, Roland Casimir