Patents by Inventor Jean-Luc Specklin

Jean-Luc Specklin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190315731
    Abstract: The invention relates to antibacterial compounds of formula I wherein the group M and R1 are as defined in the claims, and salts thereof.
    Type: Application
    Filed: May 16, 2017
    Publication date: October 17, 2019
    Inventors: Stefan DIETHELM, Azely MIRRE, Philippe PANCHAUD, Christine SCHMITT, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
  • Patent number: 10441576
    Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below and either R1 represents H and R2 represents a cleavable group as defined in the claims or R2 represents H and R1 represents a cleavable group as defined in the claims; and salts thereof.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: October 15, 2019
    Assignee: IDORSIA PHARMACEUTICALS LTD.
    Inventors: Stefan Diethelm, Philippe Panchaud, Georg Rueedi, Jean-Luc Specklin, Jean-Philippe Surivet
  • Patent number: 10314823
    Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below wherein R1, MA, MB and MC are as defined in the specification; and to salts thereof.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: June 11, 2019
    Assignee: IDORSIA PHARMACEUTICALS LTD
    Inventors: Anne-Catherine Blumstein, Gaelle Mathieu, Loïc Jacob, Florence Masse, Azely Mirre, Philippe Panchaud, Christine Schmitt, Jean-Luc Specklin, Jean-Philippe Surivet
  • Patent number: 10106544
    Abstract: The invention relates to antibacterial compounds of formula I wherein R1 is one of the groups represented below wherein A is a bond, CH?CH or C?C; U is N or CH; V is N or CH; W represents N or CH; and R1A, R2A, R3A, R1B and R1C are as defined in the claims; and salts thereof.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: October 23, 2018
    Assignee: IDORSIA PHARMACEUTICALS LTD
    Inventors: Gaelle Chapoux, Jean-Christophe Gauvin, Azely Mirre, Philippe Panchaud, Christine Schmitt, Jean-Luc Specklin, Jean-Philippe Surivet
  • Patent number: 10087171
    Abstract: The present invention relates to crystalline forms of cadazolid.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: October 2, 2018
    Inventors: Christian Hubschwerlen, Philippe Panchaud, Timo Rager, Jean-Luc Specklin
  • Publication number: 20180250273
    Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below wherein R1, MA, MB and MC are as defined in the specification; and to salts thereof.
    Type: Application
    Filed: September 2, 2016
    Publication date: September 6, 2018
    Applicant: IDORSIA PHARMACEUTICALS LTD.
    Inventors: Anne-Catherine BLUMSTEIN, Gaelle MATHIEU, Loïc JACOB, Florence MASSE, Azely MIRRE, Philippe PANCHAUD, Christine SCHMITT, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
  • Publication number: 20180235938
    Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below and either R1 represents H and R2 represents a cleavable group as defined in the claims or R2 represents H and R1 represents a cleavable group as defined in the claims; and salts thereof.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 23, 2018
    Inventors: Stefan DIETHELM, Philippe PANCHAUD, Georg RUEEDI, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
  • Publication number: 20180179196
    Abstract: The present invention relates to crystalline forms of cadazolid.
    Type: Application
    Filed: December 18, 2017
    Publication date: June 28, 2018
    Inventors: Christian HUBSCHWERLEN, Philippe PANCHAUD, Timo RAGER, Jean-Luc SPECKLIN
  • Publication number: 20170355687
    Abstract: The invention relates to antibacterial compounds formula I wherein R1 is the group M, whereby M is one of the groups MA and MB represented below wherein A is a bond or C?C; R1A is H or halogen; R2A is H or halogen; R3A is H, alkoxy, hydroxyalkoxy, hydroxyalkyl, dihydroxyalkyl, 2-hydroxyacetamido, substituted cycloprop-1-yl or substituted oxetan-3-yl; and R1B is hydroxyalkyl, dihydroxyalkyl, aminoalkyl, dialkylaminoalkyl, substituted cycloprop-1-yl, substituted cyclobutan-1-yl, substituted oxetan-3-yl, 3-hydroxythietan-3-yl, substituted azetidin-3-yl, trans-(cis-3,4-dihydroxy)-cyclopent-1-yl, 3-hydroxymethylbicyclo[1,1,1]pentan-1-yl, 4-hydroxytetrahydro-2H-pyran-4-yl, (3R,6S)-3-aminotetrahydro-2H-pyran-6-yl, piperidin-4-yl or 1-(2-hydroxyacetyppiperidin-4-yl; and salts thereof.
    Type: Application
    Filed: November 18, 2015
    Publication date: December 14, 2017
    Inventors: Gaelle CHAPOUX, Azely MIRRE, Christine SCHMITT, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
  • Publication number: 20170107223
    Abstract: The invention relates to antibacterial compounds of formula I wherein R1 is one of the groups represented below wherein A is a bond, CH?CH or C?C; U is N or CH; V is N or CH; W represents N or CH; and R1A, R2A, R3A, R1B and R1C are as defined in the claims; and salts thereof.
    Type: Application
    Filed: March 3, 2015
    Publication date: April 20, 2017
    Inventors: Gaelle CHAPOUX, Jean-Christophe GAUVIN, Azely MIRRE, Philippe PANCHAUD, Christine SCHMITT, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
  • Patent number: 9624206
    Abstract: The invention relates to antibacterial compounds of formula I wherein X is N or CH; R1 is H or halogen; R2 is alkynyloxy or the group M; R3 is H or halogen; M is one of the groups MA and MB represented below wherein A is a bond, CH2CH2, CH?CH or C?C; R1A is H or halogen; R2A is H, alkoxy or halogen; R3A is H, alkoxy, hydroxyalkoxy, alkoxyalkoxy, thioalkoxy, trifluoromethoxy, amino, hydroxyalkyl, 2-hydroxyacetamido, 1-aminocyclopropyl, 1-hydroxymethyl-cycloprop-1-yl, 1-((phosphonooxy)methyl)cyclopropyl, 1-(((dimethylglycyl)oxy)methyl)cyclopropyl, trans-2-hydroxymethyl-cycloprop-1-yl, 1,2-dihydroxyethyl, 3-hydroxyoxetan-3-yl, 3-(hydroxyalkyl)oxetan-3-yl, 3-aminooxetan-3-yl, 3-hydroxythietan-3-yl, morpholin-4-ylalkoxy, morpholin-4-yl-alkyl, oxazol-2-yl or [1,2,3]triazol-2-yl; and R1B is hydroxyalkyl, dihydroxyalkyl, aminoalkyl, 1-hydroxymethyl-cycloprop-1-yl, 1-aminomethyl-cycloprop-1-yl, trans-2-hydroxymethyl-cycloprop-1-yl, 3-hydroxyoxetan-3-yl, 3-hydroxythietan-3-yl, 1-(2-hydroxyacetyl)azetidin-3-yl,
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: April 18, 2017
    Assignee: ACTELION PHARMACEUTICALS LTD
    Inventors: Gaelle Chapoux, Jean-Christophe Gauvin, Christian Hubschwerlen, Azely Mirre, Etienne Ochala, Jean-Luc Specklin, Jean-Philippe Surivet
  • Publication number: 20170029411
    Abstract: The invention relates to antibacterial compounds of formula I wherein X is N or CH; R1 is H or halogen; R2 is alkynyloxy or the group M; R3 is H or halogen; M is one of the groups MA and MB represented below wherein A is a bond, CH2CH2, CH?CH or C?C; R1A is H or halogen; R2A is H, alkoxy or halogen; R3A is H, alkoxy, hydroxyalkoxy, alkoxyalkoxy, thioalkoxy, trifluoromethoxy, amino, hydroxyalkyl, 2-hydroxyacetamido, 1-aminocyclopropyl, 1-hydroxymethyl-cycloprop-1-yl, 1-((phosphonooxy)methyl)cyclopropyl, 1-(((dimethylglycyl)oxy)methyl)cyclopropyl, trans-2-hydroxymethyl-cycloprop-1-yl, 1,2-dihydroxyethyl, 3-hydroxyoxetan-3-yl, 3-(hydroxyalkyl)oxetan-3-yl, 3-aminooxetan-3-yl, 3-hydroxythietan-3-yl, morpholin-4-ylalkoxy, morpholin-4-yl-alkyl, oxazol-2-yl or [1,2,3]triazol-2-yl; and R1B is hydroxyalkyl, dihydroxyalkyl, aminoalkyl, 1-hydroxymethyl-cycloprop-1-yl, 1-aminomethyl-cycloprop-1-yl, trans-2-hydroxymethyl-cycloprop-1-yl, 3-hydroxyoxetan-3-yl, 3-hydroxythietan-3-yl, 1-(2-hydroxyacetyl)azetidin-3-yl,
    Type: Application
    Filed: December 18, 2014
    Publication date: February 2, 2017
    Applicant: ACTELION PHARMACEUTICALS LTD
    Inventors: Gaelle CHAPOUX, Jean-Christophe GAUVIN, Christian HUBSCHWERLEN, Azely MIRRE, Etienne OCHALA, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
  • Publication number: 20150336992
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Application
    Filed: August 3, 2015
    Publication date: November 26, 2015
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Müller, Michael W. Cappi
  • Patent number: 9133213
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: September 15, 2015
    Assignee: Morphochem Aktiengesellschaft Für Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Müller, Michael W. Cappi
  • Publication number: 20130296275
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Application
    Filed: July 2, 2013
    Publication date: November 7, 2013
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Müller, Michael W. Cappi
  • Patent number: 8513231
    Abstract: The present invention relates to the use of compounds, in which the pharmacophores of quinolone and oxazolidinone are chemically linked together through a linker that is stable under physiological conditions, for the treatment of anthrax and other infections.
    Type: Grant
    Filed: August 28, 2012
    Date of Patent: August 20, 2013
    Assignee: Morphochem Aktiengesellschaft fü Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Hans Locher, Christine Schmitt
  • Patent number: 8501774
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: August 6, 2013
    Assignee: Morphochem Aktiengesellschaft für Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Muller, Michael W. Cappi
  • Publication number: 20120322766
    Abstract: The present invention relates to the use of compounds, in which the pharmacophores of quinolone and oxazolidinone are chemically linked together through a linker that is stable under physiological conditions, for the treatment of anthrax and other infections.
    Type: Application
    Filed: August 28, 2012
    Publication date: December 20, 2012
    Applicant: Morphochem Aktiengesellschaft fuer Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Hans Locher, Christine Schmitt
  • Patent number: 8329908
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: December 11, 2012
    Assignee: Morphochem Aktiengesellschaft fur Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin
  • Patent number: 8268812
    Abstract: The present invention relates to the use of compounds, in which the pharmacophores of quinolone and oxazolidinone are chemically linked together through a linker that is stable under physiological conditions, for the treatment of anthrax and other infections.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: September 18, 2012
    Assignee: Morphochem Aktiengesellschaft fül Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Hans Locher, Christine Schmitt