Abstract: In an embodiment, a medicament delivery system is provided. The medicament delivery system includes a container for storing a medicament prior to use, the container having a first end and a second end, an injection member in fluid communication with the container, an actuation mechanism associated with the container and configured to deliver the medicament from the container through the injection member when the actuation mechanism is activated. The medicament delivery system further includes at least one detection element associated with the system, wherein in a first mode of operation of the system, medicament is delivered through the injection member and in a second mode of operation of the system, medicament is not delivered through the injection member, and the mode of operation is dependent on an output from the at least one detection element.

Abstract: In one non-limiting embodiment, there is provided a collateral device for use with one or more medicament devices including a collateral device housing and an opening extending there between, the opening configured to receive an adapter, at least a first sensor associated with the collateral device housing for detecting receipt of the portion of one or more medicament devices into the opening, and detecting actuation of an actuation mechanism of the medicament device; and an adapter receivable within the opening, the adapter comprising a receptacle for receiving and guiding a portion of a medicament device to a target surface.

Abstract: In an embodiment, an injection simulation device is provided including a housing defining a channel, the housing comprising a proximal end and a distal end, a plunger comprising a plunger rod body having a proximal end and a distal end and a stopper disposed at the distal end of the plunger rod, the plunger movable proximally and distally within the channel; and a friction feature associated with the housing, the friction feature for interfacing with the plunger rod, wherein the plunger moves in a distal direction relative to the housing to simulate medicament delivery and in a proximal direction to reset the injection simulation device, wherein the friction feature optionally causes differential resistance on the plunger rod, when the plunger rod moves in either the distal or proximal direction.

Abstract: Methods and systems for performing robotically-assisted surgery in conjunction with intra-operative imaging. A method includes moving a robotic arm with respect to a patient and an imaging device to move an end effector of the robotic arm to a pre-determined position and orientation with respect to the patient based on imaging data of the patient obtained by the imaging device. The robotic arm maintains the end effector in the pre-determined position and orientation with respect to the patient and does not collide with the imaging device or with the patient when the imaging device moves with respect to the patient.

Abstract: Methods and systems for performing robotically-assisted surgery in conjunction with intra-operative imaging. A method includes moving a robotic arm with respect to a patient and an imaging device to move an end effector of the robotic arm to a pre-determined position and orientation with respect to the patient based on imaging data of the patient obtained by the imaging device. The robotic arm maintains the end effector in the pre-determined position and orientation with respect to the patient and does not collide with the imaging device or with the patient when the imaging device moves with respect to the patient.

Abstract: Disclosed is a system for providing personalized self-medication, onboarding, training and improving medication adherence. The system includes a patient computer system comprising at least one processor and at least one memory component: a display, an optional input device, and an optional pointing device, a server connected to the patient computer system by a network link, the server comprising at least one processor and at least one computer readable medium wherein at least one computer readable medium comprises instructions that when executed by at least one processor, cause at least one processor to perform acts comprising: (i) responsive to patient input data, producing a patient personalized assessment; (ii) formulating a customized intervention for the patient based on the patient input data and/or personalized assessment; and (iii) presenting the patient personalized assessment and/or customized intervention on the display.

Abstract: In one non-limiting embodiment, there is provided a collateral device for use with one or more medicament devices including a collateral device housing and an opening extending there between, the opening configured to receive an adapter, at least a first sensor associated with the collateral device housing for detecting receipt of the portion of one or more medicament devices into the opening, and detecting actuation of an actuation mechanism of the medicament device; and an adapter receivable within the opening, the adapter comprising a receptacle for receiving and guiding a portion of a medicament device to a target surface.

Abstract: In one embodiment, a resettable respiratory inhaler training device is provided herein. The resettable respiratory inhaler training device includes a device housing having an unlocked position and a locked position, the housing comprising a chamber; a cartridge for placement into the chamber, the cartridge comprising a body for insertion into the chamber and a base, said cartridge including a status indicator window to indicate a new or used cartridge, an aperture in the base and a shutter to selectively open or close the aperture; and a reset cap comprising a protrusion for interfacing with the aperture during reset of the device; wherein operation of the device changes the status indicator window from used to new to reset the cartridge for a subsequent use.

Abstract: In an embodiment, an injection simulation device is provided. The injection simulation device may include a housing defining an opening, the housing having a proximal end and a distal end, a plunger movable relative to the housing, the plunger comprising a first interfacing portion, and distal movement of the plunger initiates an injection simulation, a rotatable component comprising a proximal end and a distal end, and an aperture extending between the proximal and distal ends of the rotatable component for receiving a portion of the plunger, rotatable component comprising a second interfacing portion for interfacing with the first interfacing portion to rotate the rotatable component when the plunger is moved toward the proximal or distal end of the housing.

Abstract: A container for delivering a medicament to a target location includes a housing having a proximal end and a distal end, the housing including a cap locking tab at the distal end, and a vial containing the medicament. The container includes a plunger slidable within the vial from a proximal end to a distal end of the vial to dispel the medicament, an injection member associated with the distal end of the vial, such that the medicament dispelled from the vial passes through the injection member to the target location, and a slidable interaction member associated with the distal end of the vial configured to slide with the vial. An interaction between the slidable interaction member and the cap locking tab causes the cap locking tab to bias outward, and placement of a safety cap on the container after use locks the safety cap onto the container via an interaction with the cap locking tab. The container may further include a resistance feature to control movement of a plunger rod relative to the vial.

Abstract: In embodiments herein, a resettable auto injection training device is provided, wherein actuation of the device requires both safety shield actuation and actuation member actuation. The training device includes audible feedback signaling actuation and completion of injection simulation. The training device audible feedback may be provided by movement of mechanical components relative to one another in embodiments herein. Further embodiments include safety features provided by compression of the safety shield post training to lock a plunger and injection simulation device within the training device until reset.

Abstract: Methods and systems for performing robotically-assisted surgery in conjunction with intra-operative imaging. A method includes moving a robotic arm with respect to a patient and an imaging device to move an end effector of the robotic arm to a pre-determined position and orientation with respect to the patient based on imaging data of the patient obtained by the imaging device. The robotic arm maintains the end effector in the pre-determined position and orientation with respect to the patient and does not collide with the imaging device or with the patient when the imaging device moves with respect to the patient.

Abstract: Methods and systems for performing robotically-assisted surgery in conjunction with intra-operative imaging. A method includes moving a robotic arm with respect to a patient and an imaging device to move an end effector of the robotic arm to a pre-determined position and orientation with respect to the patient based on imaging data of the patient obtained by the imaging device. The robotic arm maintains the end effector in the pre-determined position and orientation with respect to the patient and does not collide with the imaging device or with the patient when the imaging device moves with respect to the patient.

Abstract: In one non-limiting embodiment, there is provided a collateral device for use with one or more medicament devices including a collateral device housing and an opening extending there between, the opening configured to receive an adapter, at least a first sensor associated with the collateral device housing for detecting receipt of the portion of one or more medicament devices into the opening, and detecting actuation of an actuation mechanism of the medicament device; and an adapter receivable within the opening, the adapter comprising a receptacle for receiving and guiding a portion of a medicament device to a target surface.

Abstract: Methods and systems for performing robot-assisted surgery, including methods for defining a boundary surface for a robotic surgery system, methods for operating a robotic arm in an image-guided surgery system, methods and systems for providing haptic feedback to a user during robot-assisted surgery, and a robotic arm for use in robot-assisted surgery.

Abstract: In an embodiment, an injection simulation device is provided including a housing defining a channel, the housing comprising a proximal end and a distal end, a plunger comprising a plunger rod body having a proximal end and a distal end and a stopper disposed at the distal end of the plunger rod, the plunger movable proximally and distally within the channel; and a friction feature associated with the housing, the friction feature for interfacing with the plunger rod, wherein the plunger moves in a distal direction relative to the housing to simulate medicament delivery and in a proximal direction to reset the injection simulation device, wherein the friction feature optionally causes differential resistance on the plunger rod, when the plunger rod moves in either the distal or proximal direction.

Abstract: Methods and systems for performing robot-assisted surgery, including methods for defining a boundary surface for a robotic surgery system, methods for operating a robotic arm in an image-guided surgery system, methods and systems for providing haptic feedback to a user during robot-assisted surgery, and a robotic arm for use in robot-assisted surgery.

Abstract: In an embodiment provided herein, an injection simulation device including a housing having a proximal end and a distal end is provided. The injection simulation device embodiment comprises a plunger having a proximal end, a distal end and being slidable relative to the housing, and a retractable injection simulation member at the distal end of the housing, at least one biasing member associated with the retractable injection simulation member and associated with the plunger, wherein a first force on a distal end of the injection simulation member causes movement of the injection simulation member from an extended position to a retracted position, to compress the first biasing member, and simulate the tactility of an injection to a user; and wherein a second force on the proximal end of the plunger asserts a third force on the first biasing member to facilitate resetting the injection simulation member to the extended position.

Abstract: An injection training device for association with a skin of a user and simulating an injection event is provided herein. In a non-limiting embodiment, the injection training device comprises a housing having an opening for receiving a container, the housing comprising at least one sensor for detecting a condition of use of the device, wherein the housing is configured to be positioned at the skin of a user during an injection event.

Abstract: Disclosed herein is a system, apparatus and method directed to patient temperature control. The system can include a control module configured to provide fluid that is heated or cooled, a heating and cooling system configured to couple with the control module and receive the fluid, and a temperature sensor coupled to the control module, the temperature sensor configured to measure a body temperature of a patient and provide signals to the control module that indicate the body temperature. The system can include a neurostimulation device coupled to the control module to provide neurostimulation to the patient. The control module can include logic, stored on non-transitory, computer-readable medium that, when executed by one or more processors, causes performance of operations including generation and transmission of first instructions to the neurostimulation device causing initiation of a first neurostimulation procedure.