Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.

Abstract: An embodiment of the present invention is a technique to process an input/output (I/O) transaction. An emulated device driver in a guest partition interacts with a virtual machine (VM) manager in processing an input/output (I/O) transaction on behalf of an application via an operating system (OS). The I/O transaction is between the application and a device. A device emulator in a service partition communicatively coupled to the emulated device driver interacts with the VM manager in processing the I/O transaction on behalf of a device specific driver via the OS. The device specific driver interfaces to the device.

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.

Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.

Abstract: A method for preventing loopback of data packets sent between entities residing on a single host. In one embodiment, an auxiliary address shared among entities residing on the host indicates that a data packet is to be routed to an entity residing on the host. In another embodiment, a source address and a target address in a data packet header are switched while being routed to a target entity residing on the host.

Abstract: Methods, apparatuses, articles, and systems for receiving a request for an allocation of one or more ephemeral ports from a pool of ephemeral ports associated with a physical device, for a virtual machine of the physical device, are described herein. In various embodiments, an ephemeral port manager of the physical device is adapted to allocate up to the one or more ephemeral ports requested from the pool of ephemeral ports, if up to the one or more ephemeral ports are available for allocation from the pool of ephemeral ports. In some embodiments, the ephemeral port manager is further adapted to mark the allocated one or more ephemeral ports as unavailable to meet an ephemeral port allocation request of another virtual machine of the physical device.

Abstract: A system for prescribing a customized medical procedure that is to be performed on an individual patient.

Abstract: A method for preventing loopback of data packets sent between entities residing on a single host. In one embodiment, an auxiliary address shared among entities residing on the host indicates that a data packet is to be routed to an entity residing on the host. In another embodiment, a source address and a target address in a data packet header are switched while being routed to a target entity residing on the host.

Abstract: Methods, apparatuses, articles, and systems for receiving a request for an allocation of one or more ephemeral ports from a pool of ephemeral ports associated with a physical device, for a virtual machine of the physical device, are described herein. In various embodiments, an ephemeral port manager of the physical device is adapted to allocate up to the one or more ephemeral ports requested from the pool of ephemeral ports, if up to the one or more ephemeral ports are available for allocation from the pool of ephemeral ports. In some embodiments, the ephemeral port manager is further adapted to mark the allocated one or more ephemeral ports as unavailable to meet an ephemeral port allocation request of another virtual machine of the physical device.

Abstract: An embodiment of the present invention is a technique to process an input/output (I/O) transaction. An emulated device driver in a guest partition interacts with a virtual machine (VM) manager in processing an input/output (I/O) transaction on behalf of an application via an operating system (OS). The I/O transaction is between the application and a device. A device emulator in a service partition communicatively coupled to the emulated device driver interacts with the VM manager in processing the I/O transaction on behalf of a device specific driver via the OS. The device specific driver interfaces to the device.

Abstract: A method of cooling a locomotive engine wherein the temperature of the coolant flowing into the engine is controlled in response to the temperature of the lube oil flowing out of the engine so that the difference between these two temperatures is limited to a predetermined value in order to limit the differential expansion between parts within the engine. The predetermined value may be a function of the lube oil temperature, and it may have an absolute maximum value. In the event that the temperature difference exceeds a predetermined value, the power output of the engine may be reduced as a function of the length of time that the temperature difference limit has been exceeded. The rate of change in coolant temperature may be limited during periods of decreasing lube oil temperature in order to limit the duty cycle demand on coolant system components.