Abstract: A circular stapling device for performing anastomosis procedures includes an end effector that includes or is adapted to deliver probiotics to an anastomotic site during formation of the anastomosis.

Abstract: A steering assembly of a medical device may comprise a handle having a recess and first and second wire guides disposed within the recess. At least one of the first or second wire guides may be keyed to the recess to prevent rotation of the first or second wire guide within the recess. First and second wire segments may be configured to steer a sheath coupled to the steering assembly in first and second directions. The first wire segment may pass through a first gap between the first wire guide and the second wire guide. The second wire segment may pass through a second gap between the first wire guide and the second wire guide. Neither of the first nor the second gap may occupy any overlapping space.

Abstract: In some examples, a flat Bottom Shadow Ring (fBSR) is provided for processing a substrate in a processing chamber. An example fBSR comprises an overhang for covering an edge of the substrate in the processing chamber. The overhang includes a fiat zone that extends radially outward over the outer edge of the substrate.

Abstract: The present disclosure relates to a system in package having a chiplet with a first substrate and a first die deposed over the first substrate, a second die, a second substrate that the chiplet and the second die are deposed over, and a heatsink spreader deposed over the chiplet and the second die. Herein, the first substrate includes layered-cake shaped heatsink stanchions that are coupled to the first die, and the second substrate includes layered-cake shaped heatsink stanchions that are coupled to the chiplet and the second die. As such, heat generated by the first die can be dissipated by the heatsink stanchions within the first and second substrates, and heat generated by the second die can be dissipated by the heatsink stanchions within the second substrate. Furthermore, the heat generated by the first die and the second die can be dissipated by the heatsink spreader above them.

Abstract: A system in package (SiP) with an air cavity is disclosed. In one aspect, a technique to bond a lid over the air cavity that reduces the risk of cavity integrity failure is provided. More specifically, a metal ring is provided that conforms to or is congruent to a shape of a lower lip of the lid. A dielectric material covers the metal ring, and a low modulus epoxy is used to bind the lower lip of the lid to the dielectric material. The lid and metal ring may have comparable thermal coefficients, which, when coupled with the low modulus epoxy, reduces chance of gross failure of the cavity.

Abstract: A circular stapling device for performing anastomosis procedures includes an end effector that includes or is adapted to deliver probiotics to an anastomotic site during formation of the anastomosis.

Abstract: Aspects of the present disclosure provide methods, apparatuses, and systems for non-linear breathing entrainment. As described herein, “breathing entrainment” refers to guiding a user's breath or breathing. According to an aspect, an initial breathing period and a final breathing period are selected. Based on the initial and final breathing periods, a non-linear breath rate per minute sequence is determined. A guiding stimulus is output and aligned with the non-linear breath rate per minute sequence. The guiding stimulus is non-linearly altered with the non-linear breath rate per minute sequence to align with the final breathing period over an interval of time. The non-linear alterations of the guiding stimulus vary based on an amount of time the guiding stimulus has been output.

Abstract: This disclosure relates to verifying the trustworthiness of web applications. In one aspect, a method includes obtaining, by a browser of a client device, an electronic resource comprising code for a web application. The browser renders the electronic resource, including processing the code of the web application. The code causes the browser to initiate a request to a remote server. In response to processing the code, the request is generated and modified to include at least a portion of an integrity element for the web application. The modified request is sent to the remote server. A response to the request is received from the remote server. The response is based on the remote server verifying that the web application is trustworthy using the integrity element. Data is displayed based on the response.

Abstract: A tissue monitoring system includes a sensor, a sensor reader, and at least one computing device. The sensor is releasably coupled to a staple by a tether and is configured to measure a physiological parameter of tissue and convert the measurement into a signal. The sensor reader is configured to receive the signal from the sensor and the at least one computing device is configured to receive the signal from the sensor reader and process the signal into physiological data. The sensor is implanted in tissue by the staple.

Abstract: Electromagnetic shields for electronic devices, and particularly electromagnetic shields with bonding wires for sub-modules of electronic devices are disclosed. Electronic modules are disclosed that include multiple sub-modules arranged on a substrate with an electromagnetic shield arranged on or over the sub-modules. Bonding wires are disclosed that form one or more bonding wire walls along the substrate. The one or more bonding wire walls may be located between sub-modules of a module and about peripheral boundaries of the module. The electromagnetic shield may be electrically coupled to ground by way of the one or more bonding wire walls. Portions of the electromagnetic shield and the one or more bonding wire walls may form divider walls that are configured to reduce electromagnetic interference between the sub-modules or from external sources.

Abstract: A hair treatment kit comprises a hair treatment composition selected from the group of semi-permanent oxidative and/or direct dye hair colorant compositions, hair bleaching compositions, highlighting compositions, and combinations thereof, a reservoir for holding the temporary hair treatment composition, and an applicator fluidly connected to the reservoir for selectively applying the hair treatment composition to a targeted area of hair. Methods of applying the hair treatment composition comprise selectively engaging the applicator with a targeted area of hair, leaving the hair treatment composition in the targeted area for a time period, washing the hair treatment composition out of the targeted area, closing the reservoir to preserve remaining hair treatment composition for later use, and reapplying the hair treatment composition to the targeted area.

Abstract: A surgical stapling device includes a tool assembly having an anvil assembly having a staple forming surface, a cartridge assembly having a tissue contact surface, and extrusion resistant structure. The extrusion resistant structure is positioned on only one of the staple forming surface of the anvil assembly or the tissue contact surface of the cartridge assembly to reduce the amount of tissue extrusion that occurs when the tool assembly is moved from an open position to a clamped position.

Abstract: A system for detecting an anastomotic leak includes a sensor assembly implanted at an anastomosis site. The system also includes a reader configured to receive sensor signals from the sensor assembly and a computing device configured to communicate with the reader. The computing device may be configured to analyze the sensor signals to determine a status of the anastomosis site.

Abstract: A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.

Abstract: Electromagnetic shields for electronic devices, and particularly electromagnetic shields with bonding wires for sub-modules of electronic devices are disclosed. Electronic modules are disclosed that include multiple sub-modules arranged on a substrate with an electromagnetic shield arranged on or over the sub-modules. Bonding wires are disclosed that form one or more bonding wire walls along the substrate. The one or more bonding wire walls may be located between sub-modules of a module and about peripheral boundaries of the module. The electromagnetic shield may be electrically coupled to ground by way of the one or more bonding wire walls. Portions of the electromagnetic shield and the one or more bonding wire walls may form divider walls that are configured to reduce electromagnetic interference between the sub-modules or from external sources.

Abstract: An integrated insulator sealing and shielding assembly includes a rubber housing having a plurality of radial weathersheds and a tapered end adjacent an endmost radial weathershed. The tapered end has an outer surface with a ring extending outward from the outer surface. The ring is compressible. A metal end fitting is disposed adjacent to the endmost radial weathershed and receives the tapered end. The tapered end is received in a counterbore in the metal end fitting. The counterbore has a sealing surface so that interference of the ring with the sealing surface creates a compressive sealing force to form a seal.

Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for creating secure browser cookies.

Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.

Abstract: Disclosed herein are HTT repressors and methods and compositions for use of these HTT repressors. Disclosed herein are methods and compositions for diagnosing, preventing and/or treating Huntington's Disease. In particular, provided herein are methods and compositions for modifying (e.g., modulating expression of) an HD HTT allele so as to prevent or treat Huntington Disease, including mHTT repressors (that repress mHTT transcripts and thus also repress mHTT protein expression).