Abstract: The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays and combinatorial chemistry. The invention provides for aqueous based emulsions containing uniquely labeled cells, enzymes, nucleic acids, etc., wherein the emulsions further comprise primers, labels, probes, and other reactants. An oil based carrier-fluid envelopes the emulsion library on a microfluidic device, such that a continuous channel provides for flow of the immiscible fluids, to accomplish pooling, coalescing, mixing, sorting, detection, etc., of the emulsion library.

Abstract: The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.

Abstract: Articles, such as sanitary tissue products, comprising fibrous structures, and more particularly articles comprising fibrous structures comprising a plurality of fibrous elements wherein the articles exhibit improved consumer relevant properties, for example improved bulk and absorbent properties, compared to known articles and methods for making same are provided.

Abstract: The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.

Abstract: Articles, such as sanitary tissue products, including fibrous structures, and more particularly articles including fibrous structures having a plurality of fibrous elements wherein the article exhibits differential cellulose content throughout the thickness of the article and methods for making same are provided.

Abstract: A side structure for a vehicle includes a seat support structure arranged inside a vehicle body and coupled to a floor of the vehicle body, and a side sill arranged proximate to the floor of the vehicle body. A door is coupled to the vehicle body and includes a first end arranged proximate to the floor of the vehicle body and a second end arranged proximate to a top of the vehicle body. Moreover, the door includes a beam extending in a longitudinal direction of the door. A bracket is arranged inside the vehicle body and disposed between the seat support structure and the door in a lateral direction. The beam is configured to engage with the bracket during a deformation of the door.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for distributing machine learning workloads, e.g., computations for training a neural network or computing an inference using a neural network, across multiple hardware accelerators.

Abstract: Disclosed herein is one or more subtilisin variant useful for cleaning applications and in methods of cleaning. One embodiment is directed to one or more subtilisin variant, including one or more Bacillus sp. subtilisin polypeptide variant, and one or more cleaning composition comprising one or more such variant.

Abstract: The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.

Abstract: In one embodiment, a method includes generating a first visual representation of a location of a railroad station in relation to a railroad track, receiving a request for a first maintenance window, and determining that the first maintenance window is associated with the railroad station. The method further includes determining a first time period and generating a second visual representation of information associated with the railroad station during the first time period. The information includes an indication of a time that a train is scheduled to cross the railroad station during the time period. The information also includes an indication of a time duration for a second maintenance window that has been requested during the time period.

Abstract: In one aspect, a system for managing data processes in a network of computing resources is configured to: receive, from an instructor device, a parent request for execution of at least one parent data process executable by a plurality of computing resources at least one computing resource; generate at least one child request for execution of at least one corresponding child data process for routing to at least one corresponding destination device, each of the at least one child data process for executing at least a portion of the at least one parent data process, and each of the at least one child request including a respective destination key derived from at least one instructor key; and route each of the at least one child request to the at least one corresponding destination device. The at least one child request can be obtained by a supervisor server via the routing.

Abstract: In one embodiment, a method includes generating a first visual representation of a location of a railroad station in relation to a railroad track, receiving a request for a first maintenance window, and determining that the first maintenance window is associated with the railroad station. The method further includes determining a first time period and generating a second visual representation of information associated with the railroad station during the first time period. The information includes an indication of a time that a train is scheduled to cross the railroad station during the time period. The information also includes an indication of a time duration for a second maintenance window that has been requested during the time period.

Abstract: In one aspect, a system for managing data processes in a network of computing resources is configured to: receive, from an instructor device, a parent request for execution of at least one parent data process executable by a plurality of computing resources at least one computing resource; generate at least one child request for execution of at least one corresponding child data process for routing to at least one corresponding destination device, each of the at least one child data process for executing at least a portion of the at least one parent data process, and each of the at least one child request including a respective destination key derived from at least one instructor key; and route each of the at least one child request to the at least one corresponding destination device. The at least one child request can be obtained by a supervisor server via the routing.

Abstract: In one aspect, a system for managing data processes in a network of computing resources is configured to: receive, from an instructor device, a parent request for execution of at least one parent data process executable by a plurality of computing resources at least one computing resource; generate at least one child request for execution of at least one corresponding child data process for routing to at least one corresponding destination device, each of the at least one child data process for executing at least a portion of the at least one parent data process, and each of the at least one child request including a respective destination key derived from at least one instructor key; and route each of the at least one child request to the at least one corresponding destination device. The at least one child request can be obtained by a supervisor server via the routing.

Abstract: In one aspect, a system for managing data processes in a network of computing resources is configured to: receive, from an instructor device, a parent request for execution of at least one parent data process executable by a plurality of computing resources at least one computing resource; generate at least one child request for execution of at least one corresponding child data process for routing to at least one corresponding destination device, each of the at least one child data process for executing at least a portion of the at least one parent data process, and each of the at least one child request including a respective destination key derived from at least one instructor key; and route each of the at least one child request to the at least one corresponding destination device. The at least one child request can be obtained by a supervisor server via the routing.

Abstract: In one embodiment, a method includes generating a first visual representation of a location of a railroad station in relation to a railroad track, receiving a request for a first maintenance window, and determining that the first maintenance window is associated with the railroad station. The method further includes determining a first time period and generating a second visual representation of information associated with the railroad station during the first time period. The information includes an indication of a time that a train is scheduled to cross the railroad station during the time period. The information also includes an indication of a time duration for a second maintenance window that has been requested during the time period.

Abstract: A flame sensor apparatus includes a sensor assembly. The sensor assembly includes a photodiode for sensing characteristics of a flame. The photodiode outputs an electrical photocurrent. The sensor assembly includes an electrical assembly that is electrically remote from the sensor assembly. The sensor assembly includes an electric cable assembly extending from the sensor assembly to the electrical assembly. The electric cable assembly includes an electrical cable to electrically convey the photocurrent to the electrical assembly. At least the sensor assembly is configured and constructed to experience and continue to operate at a temperature at or greater than 200° C.

Abstract: In one aspect, a system for managing data processes in a network of computing resources is configured to: receive, from an instructor device, a parent request for execution of at least one parent data process executable by a plurality of computing resources at least one computing resource; generate at least one child request for execution of at least one corresponding child data process for routing to at least one corresponding destination device, each of the at least one child data process for executing at least a portion of the at least one parent data process, and each of the at least one child request including a respective destination key derived from at least one instructor key; and route each of the at least one child request to the at least one corresponding destination device. The at least one child request can be obtained by a supervisor server via the routing.

Abstract: In one aspect, a system for managing data processes in a network of computing resources is configured to: receive, from an instructor device, a parent request for execution of at least one parent data process executable by a plurality of computing resources at least one computing resource; generate at least one child request for execution of at least one corresponding child data process for routing to at least one corresponding destination device, each of the at least one child data process for executing at least a portion of the at least one parent data process, and each of the at least one child request including a respective destination key derived from at least one instructor key; and route each of the at least one child request to the at least one corresponding destination device. The at least one child request can be obtained by a supervisor server via the routing.

Abstract: A flame sensor apparatus includes a sensor assembly. The sensor assembly includes a photodiode for sensing characteristics of a flame. The photodiode outputs an electrical photocurrent. The sensor assembly includes an electrical assembly that is electrically remote from the sensor assembly. The sensor assembly includes an electric cable assembly extending from the sensor assembly to the electrical assembly. The electric cable assembly includes an electrical cable to electrically convey the photocurrent to the electrical assembly. At least the sensor assembly is configured and constructed to experience and continue to operate at a temperature at or greater than 200° C.