Abstract: Various systems, methods, and media for sourcing and recruiting candidates into an interview process are provided. Identifying information that corresponds to at least one individual is received via an interface. At least one search parameter that relates to characteristic of the individual is determined. A look-a-like profile is created using the search parameter. Data from a search area of a network is searched based on the look-a-like profile to identify at least one look-a-like candidate, with the look-a-like candidate being different than the individual and having the characteristic in common with the individual. The look-a-like profile is modified based on the first look-a-like candidate, and the data from the search area of the network is again searched based on the modified look-a-like profile to identify at least one second look-a-like candidate.

Abstract: Anti-PTK7 modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyperproliferative disorders are provided.

Abstract: Compositions comprising Achaete-scute homolog 1 (ASCL1) antibodies, and methods comprising ASCL1 antibody compositions for detecting ASCL1 expression as a diagnostic biomarker, are provided.

Abstract: Provided are novel anti-TNFSF9 antibodies and antibody drug conjugates, and methods of using such anti-TNFSF9 antibodies and antibody drug conjugates to treat cancer.

Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyperproliferative disorders are provided.

Abstract: PTK7 modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyper-proliferative disorders are provided.

Abstract: Disclosed is an applicator or handpiece configured to apply treatment energy to a segment of skin located in a tissue or skin treatment plane. The treatment energy could be RF energy, applied by a pair of bipolar RF electrodes or optical energy. The applicator includes an optical system configured to form a rectangular spot and homogenize the optical energy distribution.

Abstract: An inference task is performed using a computation device having a plurality of processing elements operable in parallel and connected via a connectivity system. Performing the task includes accepting at the device a specification of at least part of the inference task. The specification characterizes a plurality of variables and a plurality of factors, each factor being associated with a subset of the variables. Each of the processing elements is configured with data defining one or more of the plurality of factors. At each of the processing elements, computation associated with one of the factors is performed concurrently with other of the processing elements performing computation associated with different ones of the factors. Messages are exchanged via a connectivity system. The messages provide inputs and/or outputs to the processing elements for the computations associated with the factors and provide a result of performing of the at least the part of the inference task.

Abstract: In an aspect, in general, a programmable computation device performs computations of an inference task specified by a plurality of variables and a plurality of factors, each factor being associated with a subset of the variables. The device includes one or more processing elements. Each processing element includes a first storage for a definition of a factor, a second storage for data associated with the inputs and/or outputs of at least some of the computations, and one or more computation units coupled to the first storage and the second storage for performing a succession of parts of the at least some of the computations that are associated with a factor, the succession of parts defined by data in the storage for the definition of the factor.

Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyperproliferative disorders are provided.

Abstract: PTK modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyper-proliferative disorders are provided.

Abstract: A storage device includes a storage array having a group of storage elements. Each storage element can written to a discrete set of physical states. A read circuit selects one or more storage elements and generates, for each selected storage element, an analog signal representative of the physical state of the selected storage element. A signal processing circuit processes the analog signal to generate a plurality of outputs, with each output representing a degree of an association of the selected storage element with a different subset of one or more of the discrete set of physical states.

Abstract: A processor implements a network of functional nodes and communication paths between the nodes. The processor includes a plurality of circuit implementations of the functional nodes of the processor; and a plurality of signal paths implementing the communication paths linking the circuit implementations of the nodes. At least some of the signal paths are configured to pass signal values represented according to temporal patterns of signal levels on the signal paths. The processor also includes a plurality of circuit components for conversion between a signal value represented as a signal level (e.g., voltage or current level) and a signal value represented as a temporal pattern.

Abstract: An inference task is performed using a computation device having a plurality of processing elements operable in parallel and connected via a connectivity system. Performing the task includes accepting at the device a specification of at least part of the inference task. The specification characterizes a plurality of variables and a plurality of factors, each factor being associated with a subset of the variables. Each of the processing elements is configured with data defining one or more of the plurality of factors. At each of the processing elements, computation associated with one of the factors is performed concurrently with other of the processing elements performing computation associated with different ones of the factors. Messages are exchanged via a connectivity system. The messages provide inputs and/or outputs to the processing elements for the computations associated with the factors and provide a result of performing of the at least the part of the inference task.

Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyperproliferative disorders are provided.

Abstract: An approach to signal conversion adapts the signal conversion process, for example, by adapting or configuring signal conversion circuitry, according to inferred characteristics (e.g., probability distribution of value) of a signal being converted. As an example, an analog-to-digital converter (ADC) may be adapted so that its accuracy varies across the range of possible input signal values in such a way that on average the digital signal provides a higher accuracy than had the accuracy remained fixed. In another example, models (and corresponding inference circuitry) of both an input signal process and of a quantization process are used to improve signal conversion accuracy.

Abstract: A circuit includes a signal processing circuit for accepting an input and for generating a set of outputs. The input is provided in an input range that has a set of representative values, and each output represents a measure of an association of the input with one or more of the representative values. The signal processing circuit includes a group of output sections, each output section being responsive to the input of the signal processing circuit. Each output section includes one or more sigmoid generators. Each sigmoid generator is responsive to an input of the output section to generate an output that represents a sigmoid function of the input of the output section. Each output section also includes a circuitry for combining the outputs of the one or more sigmoid generators to form one of the set of outputs of the signal processing circuit. An input transformation circuit is coupled to the plurality of output sections.

Abstract: Some general aspects relate to systems and methods of analog computation using numerical representation with uncertainty. For example, a specification of a group of variables is accepted, with each variable having a set of at least N possible values. The group of variables satisfies a set of one or more constraints, and each variable is specified as a decomposition into a group of constituents, with each constituent having a set of M (e.g., M<N) possible constituent values that can be determined based on the variable values. The method also includes forming a specification for configuring a computing device that implements a network representation of the constraints based on the specification of the group of variables. The network representation includes a first set of nodes corresponding to the groups of constituents, a second set of nodes corresponding to the set of constraints, and interconnections between the first and the second sets of nodes for passing continuous-valued data.

Abstract: A storage device includes a storage array having a group of storage elements. Each storage element can written to a discrete set of physical states. A read circuit selects one or more storage elements and generates, for each selected storage element, an analog signal representative of the physical state of the selected storage element. A signal processing circuit processes the analog signal to generate a plurality of outputs, with each output representing a degree of an association of the selected storage element with a different subset of one or more of the discrete set of physical states.

Abstract: An approach to converting an analog value based on a partition of an input range produces probabilities that the input is found within each of the regions based, for example, on a noisy version of the input. In some examples, iterative and/or pipelined application of comparison circuitry is used to accumulate a set of analog representations of the output probabilities. The circuitry can be adapted or configured according to the characteristics of the degradation (e.g., according to the variance of an additive noise) and/or prior information about the distribution of the clean input (e.g., a distribution over a discrete set of exemplar values, uniformly distributed etc.).