Abstract: Disclosed is a disposable patient interface for an intraductal fluid aspiration system. The interface has a flexible tubular distal member for contacting the patient, and a rigid proximal member forming a vacuum chamber therein. The rigid member has a vacuum aperture for communication with a source of vacuum. The flexible member preferably has a low modulus of elasticity and a high tear strength, such that it can be stretched to fit over a rigid support without rupture.

Abstract: A sender driven certificate enrollment system and methods of its use are provided, in which a sender controls the generation of a digital certificate that is used to encrypt and send a document to a recipient in a secure manner. The sender compares previously stored recipient information to gathered information from the recipient. If the information matches, the sender transfers key generation software to the recipient, which produces the digital certificate, comprising a public and private key pair. The sender can then use the public key to encrypt and send the document to the recipient, wherein the recipient can use the matching private key to decrypt the document.

Abstract: A method and apparatus is provided for effecting secure document delivery in any of various document formats. A document is encrypted with the public key of a server associated with the recipient of the document, instead of with the public key of the intended recipient. The receiving server is located within a firewall. The encrypted document is forwarded to the server within the firewall. The server decrypts the document using its corresponding private key, converts the document to a now data representation, and then either forwards the document to the recipient inside the firewall, or re-encrypts the document with the public key of an intended recipient outside of the firewall or with the public key of another server that is associated with the intended recipient of the document.

Abstract: A document delivery architecture dynamically generates a private Uniform Resource Locator (URL) to distribute information. Each private URL (“PURL”) uniquely identifies an intended recipient of a document, the document or set of documents to be delivered, and (optionally) other parameters specific to the delivery process. The intended recipient of a document uses the PURL to retrieve the document. The server, upon retrieval of the document, customizes the behavior of the retrieval based upon attributes included in the PURL, as well as log information associated with the retrieval in a data base. This architecture and usage of PURLs enables secure document delivery and tracking of document receipt.

Abstract: A medical device for fragmenting objects and aspirating remaining debris enables a physician or other medical personnel quickly and easily remove objects, such as kidney stones, from a patient. The medical device can include a dual-lumen elongated member and a handle coupled to the elongated member. A first one of the lumens provides a suction passageway, and a second one of the lumens receives a laser fiber for delivering laser energy to an object, such as a kidney stone, within the patient. The handle can include a positioning mechanism to enable the physician by manual manipulation to move and hold in place the laser fiber longitudinally within the second lumen.

Abstract: A safety-sheathed blood sampling needle for use with a standard vacutainer. The needle is housed in a protective hollow body and held in place with a non-tensioned elastic band. The needle may be extended outside the cover for use without removing the cover assembly from the needle, and may be locked into the use position with one hand. Moving the needle into the use position tensions the elastic band. After the sample is taken, the needle is unlocked and retracted back into the cover by the elastic band. Upon such retraction, the element used to extend the needle is either concealed or disconnected to prevent accidental reuse of the needle.

Abstract: Disclosed is a disposable patient interface for an intraductal fluid aspiration system. The interface has a flexible tubular distal member for contacting the patient, and a proximal support portion forming a vacuum chamber therein. The support portion has a vacuum aperture for communication with a source of vacuum, and a retention structure for releasably mounting within a hand piece of an intraductal fluid aspiration system. The flexible member preferably has a low modulus of elasticity and a high tear strength, such that it can be stretched to fit over a rigid support without rupture.

Abstract: A document delivery architecture dynamically generates a private Uniform Resource Locator (URL) to distribute information. Each private URL (“PURL”) uniquely identifies an intended recipient of a document, the document or set of documents to be delivered, and (optionally) other parameters specific to the delivery process. The intended recipient of a document uses the PURL to retrieve the document. The server, upon retrieval of the document, customizes the behavior of the retrieval based upon attributes included in the PURL, as well as log information associated with the retrieval in a data base. This architecture and usage of PURLs enables secure document delivery and tracking of document receipt.

Abstract: A method is disclosed for noninvasively obtaining intraductal fluid. The method includes the use of an intraductal fluid sampling device to contact the patient, provide compression, and deliver heat thereto according to predetermined cycle characteristics. The cycle characteristics, such as compression cycle times and compression rates, may be varied and controlled by a control circuit.

Abstract: A medical device for fragmenting objects and aspirating remaining debris enables a physician or other medical personnel quickly and easily remove objects, such as kidney stones, from a patient. The medical device can include a dual-lumen elongated member and a handle coupled to the elongated member. A first one of the lumens provides a suction passageway, and a second one of the lumens receives a laser fiber for delivering laser energy to an object, such as a kidney stone, within the patient. The handle can include a positioning mechanism to enable the physician by manual manipulation to move and hold in place the laser fiber longitudinally within the second lumen.

Abstract: A method and apparatus is provided for effecting secure document delivery in any of various document formats. A document is encrypted with the public key of a server associated with the recipient of the document, instead of with the public key of the intended recipient. The receiving server is located within a firewall. The encrypted document is forwarded to the server within the firewall. The server decrypts the document using its corresponding private key, converts the document to a now data representation, and then either forwards the document to the recipient inside the firewall, or re-encrypts the document with the public key of an intended recipient outside of the firewall or with the public key of another server that is associated with the intended recipient of the document.

Abstract: A method and system sends documents from a desktop computer inside an intranet through a series of firewalls and/or proxy servers to a server residing on the Internet. A computer in an intranet system protected by a firewall or proxy server uses a software application to access the Internet. The software also encodes binary data to be sent as text. This binary data may be subdivided into smaller text packets. The text packets are sent, using HTTP, to a server outside the firewall, which has been configured to accept such text packets. The server converts the text packets back to the original binary data representation. The binary data, once resident on the internet server, can then be forwarded directly to other internet servers, internet desktop computers, printers, or fax machines.

Abstract: Disclosed is a disposable closed fluid loop for providing heat and compression to an intraductal fluid aspiration device. A plurality of bladders are configured to receive a pressurized inflation fluid, and to inflate in response thereto. The fluid is further configured to flow adjacent a heat exchanger, thereby receiving thermal energy, which it imparts to the bladders through conduction. Accordingly, the disclosed fluid loop provides heated inflation media to inflate a plurality of bladders to provide heat and compression to an intraductal fluid aspiration patient.

Abstract: Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and/or one or more breast disease markers. In addition to the diagnostic applications of the disclosed method and apparatus, a therapeutic application is also contemplated wherein intraductal fluids are noninvasively aspirated using compression, heating and suction cycles to remove toxic buildups within the fluid.

Abstract: Disclosed is a disposable patient interface for an intraductal fluid aspiration system. The interface has a flexible tubular distal member for contacting the patient, and a rigid proximal member forming a vacuum chamber therein. The rigid member has a vacuum aperture for communication with a source of vacuum. The flexible member preferably has a low modulus of elasticity and a high tear strength, such that it can be stretched to fit over a rigid support without rupture.

Abstract: Disclosed is an apparatus for noninvasive intraductal fluid aspiration. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The device is configured to provide a compression force, deliver heat, and apply a vacuum pressure to encourage the aspiration of patient fluid. The device includes an adjustable support and a movable wall for applying compression. Withdrawn fluid may be used either for diagnostic or therapeutic purposes.

Abstract: An electronic document delivery system and methods of its use are provided. A document preferably in a portable format is forwarded to a remote server (e.g. using HTTP to “push” the document to the server). The server sends a generic notification of the document to an intended recipient and the recipient can download the document from the server using local protocols. In preferred embodiments, the invention is used for the controlled delivery of portable documents from a sender to a large number of recipients. Using a network of servers that route the documents and notifications in a store and forward manner while providing routing and accounting information back to the sender.

Abstract: An e-mail firewall applies policies to e-mail messages transmitted between a first site and a plurality of second sites. The e-mail firewall includes a plurality of mail transfer relay modules for transferring e-mail messages between the first site and one of the second sites. Policy managers are used to enforce and administer selectable policies. The policies are used to determine security procedures for the transmission and reception of e-mail messages. The e-mail firewall employs signature verification processes to verify signatures in received encrypted e-mail messages. The e-mail firewall is further adapted to employ external servers for verifying signatures. External servers are also used to retrieve data that is employed to encrypt and decrypt e-mail messages received and transmitted by the e-mail firewall, respectively.

Abstract: A medical device for fragmenting objects and aspirating remaining debris enables a physician or other medical personnel quickly and easily remove objects, such as kidney stones, from a patient. The medical device can include a dual-lumen elongated member and a handle coupled to the elongated member. A first one of the lumens provides a suction passageway, and a second one of the lumens receives a laser fiber for delivering laser energy to an object, such as a kidney stone, within the patient. The handle can include a positioning mechanism to enable the physician by manual manipulation to move and hold in place the laser fiber longitudinally within the second lumen.

Abstract: A method and apparatus is provided for effecting secure document delivery in any of various document formats. A document is encrypted with the public key of a server associated with the recipient of the document, instead of with the public key of the intended recipient. The receiving server is located within a firewall. The encrypted document is forwarded to the server within the firewall. The server decrypts the document using its corresponding private key, converts the document to a now data representation, and then either forwards the document to the recipient inside the firewall, or re-encrypts the document with the public key of an intended recipient outside of the firewall or with the public key of another server that is associated with the intended recipient of the document.