Patents by Inventor Jeffrey Daniel Hillman

Jeffrey Daniel Hillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DENTAL DEVICE FOR TOOTH WHITENING
    Publication number: 20230225844
    Abstract: Dental devices are described that include isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains and genetically engineered LDH-deficient bacterial strains, which can be used to whiten teeth and treat periodontal disease.
    Type: Application
    Filed: January 16, 2023
    Publication date: July 20, 2023
    Inventor: Jeffrey Daniel Hillman
  • Hydrogen peroxide-producing bacterial composition
    Patent number: 11564785
    Abstract: The invention provides compositions that include isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains and genetically engineered LDH-deficient bacterial strains, which can be used to whiten teeth and treat periodontal disease.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: January 31, 2023
    Assignee: ProBiora Health, LLC
    Inventor: Jeffrey Daniel Hillman
  • Use of hydrogen peroxide-producing bacteria for tooth whitening
    Patent number: 11096770
    Abstract: The invention provides compositions and methods for whitening teeth of a subject comprising administering one or more isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains to an oral cavity of a subject.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: August 24, 2021
    Assignee: ProBiora Health, LLC
    Inventor: Jeffrey Daniel Hillman
  • Methods for regulating weight and size of animals
    Patent number: 10729157
    Abstract: The invention provides methods and compositions for regulating weight and size in animals.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: August 4, 2020
    Assignee: Oragenics, Inc.
    Inventors: Jeffrey Daniel Hillman, Eric W. T. Chojnicki, Ravi Shankar Orugunty
  • HYDROGEN PEROXIDE-PRODUCING BACTERIAL COMPOSITION
    Publication number: 20170319315
    Abstract: The invention provides compositions that include isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains and genetically engineered LDH-deficient bacterial strains, which can be used to whiten teeth and treat periodontal disease.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 9, 2017
    Inventor: JEFFREY DANIEL HILLMAN
  • USE OF HYDROGEN PEROXIDE-PRODUCING BACTERIA FOR TOOTH WHITENING
    Publication number: 20170245973
    Abstract: The invention provides compositions and methods for whitening teeth of a subject comprising administering one or more isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains to an oral cavity of a subject.
    Type: Application
    Filed: April 28, 2017
    Publication date: August 31, 2017
    Inventor: JEFFREY DANIEL HILLMAN
  • Use of hydrogen peroxide-producing bacteria for tooth whitening
    Patent number: 9636196
    Abstract: The invention provides compositions and methods for whitening teeth of a subject comprising administering one or more isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains to an oral cavity of a subject.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: May 2, 2017
    Assignee: ProBiora Health, LLC
    Inventor: Jeffrey Daniel Hillman
  • Identification of virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases
    Patent number: 8703436
    Abstract: The invention provides compositions and methods for the detection of Porphyromonas gingivalis and for the treatment and prevention of diseases and infections caused by P. gingivalis.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: April 22, 2014
    Assignee: University of Florida Research Foundation
    Inventors: Ann Progulske-Fox, Jeffrey Daniel Hillman, Martin Handfield
  • Identification of antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
    Patent number: 8420340
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: April 16, 2013
    Assignee: University of Florida Research Foundation
    Inventors: Martin Handfield, Jeffrey Daniel Hillman, Ann Progulske-Fox
  • Methods of Treating Lipomas and Liposarcomas
    Publication number: 20120122984
    Abstract: The invention provides methods and compositions for treating lipomas and liposarcomas. The invention also provides methods for reducing white adipose tissue and weight in animals.
    Type: Application
    Filed: August 18, 2011
    Publication date: May 17, 2012
    Inventors: Jeffrey Daniel Hillman, Eric W.T. Chojnicki, Ravi Shankar Orugunty
  • Identification of Actinobacillus actinomycetemcomitans Antigens for Use in the Diagnosis, Treatment, and Monitoring of Periodontal Diseases
    Publication number: 20110294146
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans.
    Type: Application
    Filed: May 20, 2011
    Publication date: December 1, 2011
    Inventors: Martin Handfield, Jeffrey Daniel Hillman, Ann Progulske-Fox
  • Identification of antigens for use in the diagnosis, treatment and monitoring of periodontal diseases
    Patent number: 7981631
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: July 19, 2011
    Assignee: University of Florida Research Foundation
    Inventors: Martin Handfield, Jeffrey Daniel Hillman, Ann Progulske-Fox
  • Identification of Actinobacillus actinomycetemcomitans Antigens for use in the Diagnosis, Treatment and Monitoring of Periodontal Diseases
    Publication number: 20110065132
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans.
    Type: Application
    Filed: November 22, 2010
    Publication date: March 17, 2011
    Inventors: MARTIN HANDFIELD, JEFFREY DANIEL HILLMAN, ANN PROGULSKE-FOX
  • Identification of antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
    Patent number: 7851171
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetecomitans.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: December 14, 2010
    Assignee: University of Florida Research Foundation
    Inventors: Martin Handfield, Jeffrey Daniel Hillman, Ann Progulske-Fox
  • Use of Hydrogen Peroxide-Producing Bacteria for Tooth Whitening
    Publication number: 20090311199
    Abstract: The invention provides compositions and methods for whitening teeth of a subject comprising administering one or more isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains to an oral cavity of a subject.
    Type: Application
    Filed: June 11, 2009
    Publication date: December 17, 2009
    Inventor: Jeffrey Daniel Hillman
  • In SITU Induced Antigen Technology (ISIAT) for Identification of Polynucleotides Expressed during Infection or Colonization
    Publication number: 20090247422
    Abstract: The invention provides compositions and methods for identifying polynucleotides and polypeptides expressed by a microbe during infection or colonization. The invention also provides compositions and methods for identifying polynucleotides and polypeptides expressed by a host organism in response to a disease state. The invention also provides methods and compositions for the diagnosis, treatment, prevention, and amelioration of diseases and infections caused by microbes.
    Type: Application
    Filed: December 3, 2008
    Publication date: October 1, 2009
    Inventor: Jeffrey Daniel Hillman
  • DIFFERENTIALLY PROTECTED ORTHOGONAL LANTHIONINE TECHNOLOGY
    Publication number: 20090215985
    Abstract: The present invention provides a method of synthesizing an intramolecularly bridged polypeptide comprising at least one intramolecular bridge. The present invention further provides a method of synthesizing an intramolecularly bridged polypeptide comprising two intramolecular bridges, wherein the two intramolecular bridges form two overlapping ring, two rings in series, or two embedded rings. The present invention also provides methods for synthesizing lantibiotics, including Nisin A. Additionally, the invention provides intramolecularly bridged polypeptides synthesized by the methods disclosed herein and differentially protected orthogonal lanthionines.
    Type: Application
    Filed: March 28, 2009
    Publication date: August 27, 2009
    Inventors: Kostyantyn Kirichenko, Anatoliy Vakulenko, Jeffrey Daniel Hillman
  • Identification of Actinobacillus actinomycetemcomitans Antigens for Use in the Diagnosis, Treatment, and Monitoring of Periodontal Diseases
    Publication number: 20090142782
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetecomitans.
    Type: Application
    Filed: January 9, 2009
    Publication date: June 4, 2009
    Inventors: Martin Handfield, Jeffrey Daniel Hillman, Ann Progulske-Fox
  • Identification of antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
    Patent number: 7498143
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: March 3, 2009
    Assignee: University of Florida Research Foundation
    Inventors: Martin Handfield, Jeffrey Daniel Hillman, Ann Progulske-Fox
  • Identification of Porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases
    Publication number: 20080299591
    Abstract: The invention provides compositions and methods for the detection of Porphyromonas gingivalis and for the treatment and prevention of diseases and infections caused by P. gingivalis.
    Type: Application
    Filed: July 18, 2008
    Publication date: December 4, 2008
    Inventors: Ann Progulske-Fox, Jeffrey Daniel Hillman, Martin Handfield