Patents by Inventor Jeffrey Daniel Hillman

Jeffrey Daniel Hillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases
    Patent number: 7416852
    Abstract: The invention provides compositions and methods for the detection of Porphyromonas gingivalis and for the treatment and prevention of diseases and infections caused by P. gingivalis.
    Type: Grant
    Filed: August 10, 2004
    Date of Patent: August 26, 2008
    Assignee: University of Florida Research Foundation
    Inventors: Ann Progulske-Fox, Jeffrey Daniel Hillman, Martin Handfield
  • Antimicrobial polypeptides and methods of use
    Patent number: 7067125
    Abstract: Antimicrobial compounds and compositions and uses thereof, including the treatment and prevention of bacterial infections are described. The compounds and compositions include lantibiotic polypeptides and the nucleic acid sequences encoding the polypeptides. The compounds and compositions are useful as antimicrobials in antibiotic pharmaceutical preparation and as an antimicrobial or antiseptic dentifrice.
    Type: Grant
    Filed: September 4, 2002
    Date of Patent: June 27, 2006
    Assignee: University of Florida Research Foundation
    Inventor: Jeffrey Daniel Hillman
  • Identification of antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
    Patent number: 7052860
    Abstract: Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: May 30, 2006
    Assignee: University of Florida Research Foundation
    Inventors: Martin Handfield, Jeffrey Daniel Hillman, Ann Progulske-Fox
  • Identification of microbial polynucleotides expressed during infection of a host
    Patent number: 7033748
    Abstract: The invention provides methods useful for identifying polynucleotides expressed in vivo by a microbe during infection of a host. Antibodies against antigens that are expressed by the microbe in vivo and in vitro are adsorbed with cells or cellular extracts of the microbe that have been grown in vitro. Unadsorbed antibodies are isolated and are probed against a phage display library of the microbe's DNA or RNA. A polynucleotide of the microbe that is expressed in vivo is isolated and identified.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: April 25, 2006
    Assignee: iviGene Corporation
    Inventor: Jeffrey Daniel Hillman
  • Antimicrobial polypeptide, nucleic acid, and methods of use
    Patent number: 6964760
    Abstract: Antimicrobial compounds and compositions and uses thereof, including the treatment and prevention of bacterial infections are described. The compounds and compositions include lantibiotic polypeptides and the nucleic acid sequences encoding the polypeptides. The compounds and compositions are useful as antimicrobials in antibiotic pharmaceutical preparation and as an antimicrobial or antiseptic dentifrice.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: November 15, 2005
    Assignee: University of Florida Research Foundation
    Inventor: Jeffrey Daniel Hillman
  • Identification of microbial polynucleotides expressed during infection of a host
    Publication number: 20020197625
    Abstract: The invention provides methods useful for identifying polynucleotides expressed in vivo by a microbe during infection of a host. Antibodies against antigens that are expressed by the microbe in vivo and in vitro are adsorbed with cells or cellular extracts of the microbe that have been grown in vitro. Unadsorbed antibodies are isolated and are probed against a phage display library of the microbe's DNA or RNA. A polynucleotide of the microbe that is expressed in vivo is isolated and identified.
    Type: Application
    Filed: March 6, 2002
    Publication date: December 26, 2002
    Applicant: iviGene Corporation
    Inventor: Jeffrey Daniel Hillman
  • Antimicrobial polypeptide, nucleic acid, and methods of use
    Publication number: 20020128186
    Abstract: Antimicrobial compounds and compositions and uses thereof, including the treatment and prevention of bacterial infections are described. The compounds and compositions include lantibiotic polypeptides and the nucleic acid sequences encoding the polypeptides. The compounds and compositions are useful as antimicrobials in antibiotic pharmaceutical preparation and as an antimicrobial or antiseptic dentifrice.
    Type: Application
    Filed: October 30, 2001
    Publication date: September 12, 2002
    Inventor: Jeffrey Daniel Hillman