Abstract: The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In particular, the present invention relates to identification and characterization of the receptor for leptin, including a naturally occurring soluble form of the receptor that is expected to modulate leptin activity, in particular to agonize leptin activity. The invention further relates to the nucleic acids encoding the receptor, and to methods for using the receptor, e.g., to identify leptin analogs, therapeutically, such as in gene therapy or in soluble form as an agonist or antagonist of leptin activity, or diagnostically.

Abstract: The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In particular, the present invention relates to identification and characterization of the receptor for leptin, including a naturally occurring soluble form of the receptor that is expected to modulate leptin activity, in particular to agonize leptin activity. The invention further relates to the nucleic acids encoding the receptor, and to methods for using the receptor, e.g., to identify leptin analogs, therapeutically, such as in gene therapy or in soluble form as an agonist or antagonist of leptin activity, or diagnostically.

Abstract: The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In particular, the present invention relates to identification and characterization of the receptor for leptin, including a naturally occurring soluble form of the receptor that is expected to modulate leptin activity, in particular to agonize leptin activity. The invention further relates to the nucleic acids encoding the receptor, and to methods for using the receptor, e.g., to identify leptin analogs, therapeutically, such as in gene therapy or in soluble form as an agonist or antagonist of leptin activity, or diagnostically.

Abstract: A lobby or other public space design process for providing an attractive appearance complementary to a building in which the lobby is installed, by (a) Evaluating a building for determination of appropriate lobby interior design architecture and appearance, (b) Selecting a suitable design from a series of previously prepared design proposals, and (c) Selecting material for the decoration of the lobby interior for the design selected from a palette of previously prepared options for available material including selection of material type, color and design.

Abstract: An Elevator cab design process for providing an attractive appearance complementary to a building in which the elevator is installed, by a) Evaluating a building for determination of appropriate elevator cab interior design architecture and appearance' b) Selecting a suitable design from a Series of previously prepared Design proposals c) Selecting material for the declaration of the cab interior for the design selected from a palette of previously prepared options for available material including selection of material type, color and design.

Abstract: This invention relates to a cost saving way of solving a difficult problem in the structure and installation and leveling of an elevator sill. This invention provides ease of installing from the hallway without the use of a moving elevator platform. The structure consists of a sill, a cradle for the sill and a pair of end brackets for supporting the cradle. The pair of spaced L-shaped end brackets are provided for attachment to the hall floor. A vertically adjustable sill cradle is supported at its end portions by the brackets and a horizontally and vertically adjustable sill is mounted on the sill cradle. The elevator door sill cradle is adjustable vertically by means of fasteners that are moveable in vertical slots in the end brackets and is horizontally adjustable on the cradle by means of fasteners that are moveable in horizontal slots provided in the cradle.

Abstract: New elevator cab construction and reconstruction of old elevator cabs are frequently presented with the problem of increasing the interior size of the elevator cab in an elevator shaft of limited size. This invention relates to an elevator cab design providing a novel way of increasing internal cab size of a standard elevator cab while still retaining decorative design features by having removable decorative panels. The elevator cab is constructed of the normal elements, namely, a platform, a ceiling, cab shell walls, stiffeners and corner stiffener risers. The cab shell walls have a base and transom and shell panels there between designed to overlap one another so as to be readily attached by spot welding or adhesive. The stiffeners are hat-shaped elongated sections typically of stainless steel that are attached to the inside of the shell panels. The stiffeners may also be formed by hat-shaped ribs formed in the shell panels.

Abstract: An Elevator cab design process for providing an attractive appearance complementary to a building in which the elevator is installed, by

Abstract: This invention relates to a cost saving way of solving a difficult problem in the structure and installation and leveling of an elevator sill.

Abstract: The image formation system of the invention provides a compact apparatus for viewing indicia on a planar mirror-like (specular) substrate, such as a semiconductor wafer. The invention is particularly effective in viewing indicia that require either brightfield or high-angle darkfield illumination. These and other benefits of the invention are provided in part by providing selective directional focusing and defocusing of the reflected image of the illumination elements that illuminate the indicia, while providing substantial focusing of the image of the indicia at high contrast. In the case of high-angle darkfield illumination, directionally selective focusing maximizes useful darkfield area by minimizing interference between the reflected image of the illumination sources and the image of the indicia, while the contrast of the image of the indicia is maximized.