Patents by Inventor Jeffrey L. Goldberg

Jeffrey L. Goldberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10478332
    Abstract: In certain aspects, the present invention is directed to a device selected from (a) an operating microscope with an attached or attachable magnet and (b) a magnet that is configured for attachment to an operating microscope. In either case, the magnet is configured to allow a patient's tissue to be viewed through the operating microscope while at the same time permitting the creation of a magnetic field of sufficient magnitude and direction to move a magnetic therapeutic and/or diagnostic agent lying within the tissue to a preferred location in the tissue.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: November 19, 2019
    Assignee: EMMETROPE OPHTHALMICS LLC.
    Inventors: Jeffrey L. Goldberg, Roger A. Goldberg
  • Publication number: 20190307605
    Abstract: In certain aspects, the invention is directed to magnetic eye shields that comprise a magnet. When worn by a patient, the magnetic eye shields are configured to generate an intraocular magnetic field of sufficient magnitude and direction to move a magnetic therapeutic and/or diagnostic agent positioned inside the eye to target tissue within the eye. Other aspects of the invention pertain to kits which comprise such magnetic eye shields as well as one or more additional components, for example, one or more containers of a magnetic diagnostic and/or or therapeutic agent. Further aspects of the invention pertain to methods of treatment, which comprise intraocularly introducing a magnetic therapeutic and/or diagnostic agent into an eye of a patient and fitting a magnetic eye shield to the head of the patient, wherein the magnetic therapeutic and/or diagnostic agent may be introduced to the patient before or after fitting the magnetic eye shield to the head of the patient.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 10, 2019
    Inventors: Jeffrey L. Goldberg, Roger A. Goldberg, Noelia J. Kunzevitzky, Dillon Joseph Rak
  • Patent number: 10406242
    Abstract: Normal or genetically modified cell(s) having magnetic nanoparticle(s) bound (affixed) to their surfaces and methods of delivery to target tissues, e.g. for treatment of disease and/or injury.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: September 10, 2019
    Assignee: Emmetrope, Inc.
    Inventors: Jeffrey L. Goldberg, Alan Halpern
  • Publication number: 20190210223
    Abstract: A system for analyzing geometric properties for an object includes designing the object in a first computer process and producing information relating to the geometric properties of the object, and receiving the information in a second computer processor which identifies a first portion of the geometric property information as masked or private and second portion identified as public or shared, analysis is performed by the second processor on the public/shared portion of the geometric property information. An output based on the analysis may be provided to an industrial system performing processes on the object. A binary privacy label may be assigned to each triangle in a set of triangles representing the surfaces of the object in a 3D object mesh. The privacy label denotes an associated triangle as being private or shared. The system may be used to produce a set of planned grasps for a robotic gripper.
    Type: Application
    Filed: August 16, 2017
    Publication date: July 11, 2019
    Inventors: Kenneth Yigael Goldberg, Ramu Chandra, Florian Till Pokorny, Jeffrey Brian Mahler, Juan L. Aparicio Ojea
  • Patent number: 10327945
    Abstract: In certain aspects, the invention is directed to magnetic eye shields that comprise a magnet. When worn by a patient, the magnetic eye shields are configured to generate an intraocular magnetic field of sufficient magnitude and direction to move a magnetic therapeutic and/or diagnostic agent positioned inside the eye to target tissue within the eye. Other aspects of the invention pertain to kits which comprise such magnetic eye shields as well as one or more additional components, for example, one or more containers of a magnetic diagnostic and/or or therapeutic agent. Further aspects of the invention pertain to methods of treatment, which comprise intraocularly introducing a magnetic therapeutic and/or diagnostic agent into an eye of a patient and fitting a magnetic eye shield to the head of the patient, wherein the magnetic therapeutic and/or diagnostic agent may be introduced to the patient before or after fitting the magnetic eye shield to the head of the patient.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: June 25, 2019
    Assignee: Emmetrope, Inc.
    Inventors: Jeffrey L. Goldberg, Roger A. Goldberg, Noelia J. Kunzevitzky, Dillon Joseph Rak
  • Patent number: 10070953
    Abstract: A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releasably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: September 11, 2018
    Assignee: ENDOSHIELD, LLC
    Inventors: Jeffrey L. Goldberg, Jean-Marie Parel, Francisco Fantes
  • Publication number: 20180154021
    Abstract: Normal or genetically modified cell(s) having magnetic nanoparticle(s) bound (affixed) to their surfaces and methods of delivery to target tissues, e.g. for treatment of disease and/or injury.
    Type: Application
    Filed: December 4, 2017
    Publication date: June 7, 2018
    Inventors: Jeffrey L. Goldberg, Alan Halpern
  • Publication number: 20180021404
    Abstract: Provided are methods and compositions for treating an ocular disease associated with increased intraocular pressure using a therapeutically effective amount of receptor associated protein (RAP), a derivative of RAP, a variant of RAP, or a fragment of RAP. Also provided are methods and compositions for reducing intraocular pressure.
    Type: Application
    Filed: February 19, 2016
    Publication date: January 25, 2018
    Inventors: Jeffrey L. Goldberg, Travis L. Stiles
  • Publication number: 20170367814
    Abstract: A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releaseably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region.
    Type: Application
    Filed: August 10, 2017
    Publication date: December 28, 2017
    Inventors: Jeffrey L. Goldberg, Jean-Marie Parel, Francisco Fantes
  • Patent number: 9833517
    Abstract: Normal or genetically modified cell(s) having magnetic nanoparticle(s) bound (affixed) to their surfaces and methods of delivery to target tissues, e.g. For treatment of disease and/or injury.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: December 5, 2017
    Assignee: EMMETROPE, INC.
    Inventors: Jeffrey L. Goldberg, Alan Halpern
  • Patent number: 9757226
    Abstract: A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releaseably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: September 12, 2017
    Assignee: ENDOSHIELD, LLC
    Inventors: Jeffrey L. Goldberg, Jean-Marie Parel, Francisco Fantes
  • Publication number: 20160184086
    Abstract: A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releaseably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region.
    Type: Application
    Filed: March 7, 2016
    Publication date: June 30, 2016
    Inventors: Jeffrey L. Goldberg, Jean-Marie Parel, Francisco Fantes
  • Publication number: 20160102290
    Abstract: The present invention provides methods for the identification, isolation and/or enrichment of human corneal endothelial cells (HCECs). In some embodiments, the method comprises a positive selection process in which a cell population containing human corneal cells is contacted with a positive affinity reagent that selectively binds to HCECs relative to cells other than HCECs (e.g., corneal keratocytes, etc.) in the population and/or a negative selection process in which a cell population containing HCECs is contacted with a negative affinity reagent that selectively binds to cells other than HCECs in the population relative to HCECs. The present invention also provides reagents and kits for the identification, isolation and/or enrichment of HCECs as well as compositions that are enriched in HCECs.
    Type: Application
    Filed: May 2, 2014
    Publication date: April 14, 2016
    Inventors: Jeffrey L. Goldberg, Noelia J. Zevitzky
  • Patent number: 9308083
    Abstract: A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releaseably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region and having a biasing configuration structured to be disposed in contacting relation with the iris and/or iridocorneal angle in biasing relation of the central region against the posterior cornea.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: April 12, 2016
    Assignee: Endoshield, LLC
    Inventors: Jeffrey L. Goldberg, Jean-Marie Parel, Francisco Fantes
  • Publication number: 20160089452
    Abstract: Normal or genetically modified cell(s) having magnetic nanoparticle(s) bound (affixed) to their surfaces and methods of delivery to target tissues, e.g. For treatment of disease and/or injury.
    Type: Application
    Filed: July 13, 2015
    Publication date: March 31, 2016
    Applicant: EMMETROPE, INC.
    Inventors: Jeffrey L. GOLDBERG, Alan Halpern
  • Publication number: 20160022485
    Abstract: In certain aspects, the present invention is directed to a device selected from (a) an operating microscope with an attached or attachable magnet and (b) a magnet that is configured for attachment to an operating microscope. In either case, the magnet is configured to allow a patient's tissue to be viewed through the operating microscope while at the same time permitting the creation of a magnetic field of sufficient magnitude and direction to move a magnetic therapeutic and/or diagnostic agent lying within the tissue to a preferred location in the tissue.
    Type: Application
    Filed: February 6, 2014
    Publication date: January 28, 2016
    Applicant: EMMETROPE OPHTHALMICS LLC
    Inventors: Jeffrey L. GOLDBERG, Roger A. GOLDBERG
  • Publication number: 20150305929
    Abstract: In certain aspects, the invention is directed to magnetic contact lenses that comprise one or more magnets. When worn by a patient, the magnetic contact lenses are configured to generate an intraocular magnetic field of sufficient magnitude and direction to move a magnetic therapeutic and/or diagnostic agent positioned inside the eye to target tissue within the eye. Other aspects of the invention pertain to kits which comprise such magnetic contact lenses as well as one or more additional components, for example, one or more containers of a magnetic diagnostic and/or or therapeutic agent. Further aspects of the invention pertain to methods of treatment, which comprise intraocularly introducing a magnetic therapeutic and/or diagnostic agent into an eye of a patient and fitting a magnetic contact lens to the head of the patient, wherein the magnetic therapeutic and/or diagnostic agent may be introduced to the patient before or after fitting the magnetic contact lens to the head of the patient.
    Type: Application
    Filed: November 5, 2013
    Publication date: October 29, 2015
    Applicant: EMMETROPE OPHTHALMICS LLC
    Inventors: Jeffrey L. Goldberg, Roger A. Goldberg, Noelia J. Kunzevitzky, Stavros Nickolas Moysidis
  • Publication number: 20150238357
    Abstract: In certain aspects, the invention is directed to magnetic eye shields that comprise a magnet. When worn by a patient, the magnetic eye shields are configured to generate an intraocular magnetic field of sufficient magnitude and direction to move a magnetic therapeutic and/or diagnostic agent positioned inside the eye to target tissue within the eye. Other aspects of the invention pertain to kits which comprise such magnetic eye shields as well as one or more additional components, for example, one or more containers of a magnetic diagnostic and/or or therapeutic agent. Further aspects of the invention pertain to methods of treatment, which comprise intraocularly introducing a magnetic therapeutic and/or diagnostic agent into an eye of a patient and fitting a magnetic eye shield to the head of the patient, wherein the magnetic therapeutic and/or diagnostic agent may be introduced to the patient before or after fitting the magnetic eye shield to the head of the patient.
    Type: Application
    Filed: May 7, 2015
    Publication date: August 27, 2015
    Applicant: EMMETROPE OPHTHALMICS LLC
    Inventors: Jeffrey L. Goldberg, Roger A. Goldberg, Noelia J. Kunzevitzky
  • Patent number: 9078932
    Abstract: Normal or genetically modified cell(s) having magnetic nanoparticle(s) bound (affixed) to their surfaces and methods of delivery to target tissues, e.g. for treatment of disease and or injury.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: July 14, 2015
    Assignee: EMMETROPE, INC.
    Inventors: Jeffrey L. Goldberg, Alan Halpern
  • Publication number: 20150005876
    Abstract: A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releaseably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region and having a biasing configuration structured to be disposed in contacting relation with the iris and/or iridocorneal angle in biasing relation of the central region against the posterior cornea.
    Type: Application
    Filed: October 16, 2012
    Publication date: January 1, 2015
    Inventors: Jeffrey L. Goldberg, Jean-Marie Parel, Francisco Fantes