Abstract: A flow control valve includes a valve body having a first section and a second section attached to the first section. A flow control member is positioned within the valve body and a shaft extends through the valve body and is connected to the flow control member to move the flow control member between an open position and a closed position. A sealing gasket is positioned within the valve body and engages the valve body to prevent the flow of fluid between the first section and the second section. The sealing gasket has an annular metallic body having an inner surface and an opposing outer surface, the outer surface defining a primary sealing surface, a groove formed in the outer surface, and an insert positioned within the groove, the insert defining a secondary sealing surface.

Abstract: A dispensing fitment assembly includes a fitment assembly and a dispensing probe. The fitment assembly includes a fitment housing and a plug. The fitment housing is configured to operatively couple to a container opening of a fluid container. The plug is positioned within an interior portion of the fitment housing. The plug is slidingly movable between an open and closed position. Engagement between the dispensing probe and the interior surface of the plug is configured to move the plug from the closed position to the open position. Disengagement between the dispensing probe and the interior surface of the plug is configured to move the plug from the open to closed position.

Abstract: Novel tetrahydroisoquinoline derivative compounds are disclosed herein that may be used as an active ingredient for a pharmaceutical composition, and in particular, for a pharmaceutical composition useful for preventing or treating a disease or condition responsive to modulation of the contractility of the skeletal sarcomere. This may be accomplished, for example, by modulation of the troponin complex of the fast skeletal muscle sarcomere through one or more of fast skeletal myosin, actin, tropomyosin, troponin C, troponin I, and troponin T, and fragments and isoforms thereof. The tetrahydroisoquinoline derivative compounds can thus be used as an agent for preventing or treating 1) neuromuscular disorders, 2) disorders of voluntary muscle, 3) CNS disorders in which muscle weakness, atrophy, and fatigue are prominent symptoms, 4) muscle symptoms stemming from systemic disorders, and 5) dysfunctions of pelvic floor and urethral/anal sphincter muscle.

Abstract: Playback devices can support playing back audio content of audio-visual content received from a media service, while corresponding video content is synchronously played back on a video display device. In some examples, the device can cause the video display device to display a graphical user interface that includes a plurality of media services associated with a user account, receive a user selection for media playback of audio-visual content from one of the media services, transmit a request for the user-selected audio-visual content to the selected media service, and receive audio and video content of the audio-visual content.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra1, Ra2, Ra4, Ra5, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: A controller for a fuel cell based power generator includes a memory and a processor configured to execute executable instructions stored in the memory to receive a pressure in an anode loop of the fuel cell based power generator, wherein the anode loop includes a hydrogen generator and an anode loop blower, and control the anode loop blower such that the hydrogen generator provides hydrogen to an anode of a fuel cell via the blower and the anode loop at a controlled pressure. In further embodiments, the temperatures of the fuel cell and hydrogen generator are independently controlled.

Abstract: Apparatus and methods for limiting trailing edge deflection in aircraft folding wing tips are disclosed herein. An example aircraft wing disclosed herein includes a fixed wing portion. The fixed wing portion includes an outboard rib. The aircraft wing also includes a wing tip moveably coupled to the fixed wing portion. The wing tip is moveable between an extended position and a folded position. The wing tip includes an inboard rib that is disposed in a trailing edge section of the wing tip. The wing tip includes a stop plate coupled to the inboard rib. The stop plate extends inboard from the inboard rib such that when the wing tip is in the extended position, the stop plate is disposed below a portion of the outboard rib of the fixed wing portion to limit upward deflection of the trailing edge section of the wing tip relative to the fixed wing portion.

Abstract: A fan carrier system, including a fan carrier, including: a fan apparatus having i) a first end positioned opposite to a second end, and ii) a first side positioned opposite to a second side, the first and the second side extending between the first end and the second end; a first piston coupled to the fan apparatus, the first piston positioned along the first side, the first piston translatable between the first end and the second end; a connection assembly coupled to a first end of the first piston, the connection assembly including a first connector; a handle assembly, including: a first arm coupled to the first piston via a first handle pin, the first arm further including a first carrier pin; a handle coupled to the first arm; a chassis, including: a first wall and a second wall each including a respective slot.

Abstract: An acoustic attenuation structure for a gas turbine engine includes a periodic structure having a first unit cell, the first unit cell having a first central body and a first axial tube disposed on the first central body and a second axial tube disposed on the first central body, opposite the first axial tube, each of the first axial tube and the second axial tube being in fluid communication with one another through the first central body.

Abstract: An insertable catheter device includes a shaft including a proximal end and a distal end, an expandable balloon, and an actuator configured to expand and retract the expandable balloon. The actuator includes a fluid conduit that extends through the shaft and is coupled with the expandable balloon to enable inflation and retraction of the expandable balloon via injection or withdrawal of a fluid to or from the expandable balloon via the fluid conduit. The expandable balloon is displaceably retractable into the shaft and extendable from the shaft. A fluid pump is coupled with the fluid conduit to pump the fluid through the fluid conduit. A patch is positioned to be displaced by the expandable balloon when the expandable balloon is inflated, and the expandable balloon is displaceably retractable into the shaft and displaceably extendable from the shaft.

Abstract: Aspects of the subject disclosure may include, a system configured for generating a signal, and inducing, by a coupler, an electromagnetic wave that propagates along a physical transmission medium. The coupler can be configured to convert the signal into a plurality of wave modes that combine to form the electromagnetic wave having an electromagnetic field configuration that reduces leakage of the electromagnetic wave as the electromagnetic wave propagates along the physical transmission medium. Other embodiments are disclosed.

Abstract: An inner mandrel for forming a variable taper component includes a plurality of interlocking pieces and a brace. Each interlocking piece defines opposed tapered edge faces, a first surface, and a tapered second surface opposite the first surface. One of the edge faces defines a locking feature and another of the edge faces defines a receiving feature engaging the locking feature of an adjacent interlocking piece. The first surface defines a variable taper and a plurality of recesses. The brace secures the plurality of interlocking pieces to each other in a concentric arrangement about a central axis. A maximum width of each of the interlocking pieces is smaller than a minimum width of an end portion of the variable taper component. A central portion of the variable taper component is wider than the end portions.

Abstract: A gap verification tool is usable with a leveling unit where the leveling unit includes multiple offset rollers that flatten a material, such as a previously coiled steel sheet, as it passes through the leveling unit. The gap verification tool includes a sensing assembly that has blades that rotate about a pivot point of the tool. An encoder of the tool measures the rotation of the blades and determines a gap between the offset rollers. A calibration stand is also usable with the tool to calibrate the tool. The calibration stand includes offset rollers setup with a known gap.

Abstract: An insight engine that takes into account a wide variety of information from a wide variety of sources for predicting a sales insight is generated. The insight engine is generated using machine learning. Historical customer-specific information, product-specific information, and environmental information are aggregated, based on customer, product, and/or time period, into historical customer profiles. The historical customer profiles are labeled with historical sales insights to form a training set. A machine learning algorithm is applied to the training set to generate an insight engine. The insight engine is applied to a target customer profile to determine a predicted sales insight for a target entity.

Abstract: Systems and methods for localization of a subject vehicle may include: a plurality of sensors to gather data regarding features in an environment of the subject vehicle; a feature map module to generate a feature map using data gathered from one or more of the plurality of sensors; a feature raster module to generate a feature raster image from the feature map; a score computation module to register a plurality of transformations of the feature raster image with a map feature raster image, to generate a cost function for the registrations of the plurality of transformations, and to determine the transformation with the lowest cost function; and the score computation module using the transformation with the lowest cost function to determine localization of the subject vehicle.

Abstract: A receiver or transmitter designed for a broad range of frequencies requires a pre-select filter for incoming signals or a post-select filter for outgoing signals to minimize spurious signal responses. In conventional receivers, several discrete RF filters are used and a switched filter bank is created utilizing a large amount of space. A filter bank comprising a plurality of stacked shielded filters would enable different filter technologies and topologies to be used together, as other passive and active circuits may be combined into the one surface mountable component in order to save on PCB space.

Abstract: A method for configuring a digital light projector (DLP) of an augmented reality (AR) display device is described. A light source component of the DLP projector is configured to generate a single red-green-blue color sequence repetition per image frame. The AR display device identifies a color sequence of the light source component of the DLP projector and tracks a motion of the AR display device. The AR display device adjusts an operation of the DLP projector based on the single red-green-blue color sequence repetition, the color sequence of the light source component of the DLP projector, and the motion of the AR display device.

Abstract: A method, computer readable medium, and processor are described herein for inline data inspection by using a decoder to decode a load instruction, including a signal to cause a circuit in a processor to indicate whether data loaded by a load instruction exceeds a threshold value. Moreover, an indication of whether data loaded by a load instruction exceeds a threshold value may be stored.

Abstract: A circuit interrupter movable among ON, OFF, and TRIP positions includes a housing, a latch situated on the housing, a number of mechanisms situated on the housing, each mechanism of the number of mechanisms including a contact arm that is movable with respect to the housing, a set of separable contacts including a stationary contact and further including a movable contact situated on the contact arm, a handle, a pin, a first spring that extends between the contact arm and the handle in at least one of the OFF position and the ON position, a second spring that extends between the handle and the pin, and the pin being movable among a position engaged with the latch in at least one of the ON position and the OFF position and another position engaged with the handle in the TRIP position.