Abstract: Described, in certain inventive embodiments, are unique devices and methods for introducing implants into soft tissue of a patient. One of these devices includes a tissue-penetrating member that is configured to pass in its entirety through a volume of patient tissue. The tissue-penetrating member has a leading end and a trailing end, and provides a receiving space for receipt of an implant body portion for carrying the implant body portion into the volume of patient tissue. The device also includes an implant that has an implant body portion removably received in the receiving space of the tissue-penetrating member. The implant body portion is configured for deployment from the receiving space in the volume of patient tissue so as to remain deployed there along a passageway traversed by the tissue-penetrating member.

Abstract: A dielectric material is disclosed comprising a plurality of substantially longitudinally oriented wires which are coupled together, wherein each of the wires includes a conductive core comprising a first material and one or more insulating shell layers comprising a compositionally different second material disposed about the core. In one embodiment, a dielectric layer is disclosed comprising a substrate comprising an insulating material having a plurality of nanoscale pores defined therein having a pore diameter less than about 100 nm, and a conductive material disposed within the nanoscale pores.

Abstract: A dielectric material is disclosed comprising a plurality of substantially longitudinally oriented wires which are coupled together, wherein each of the wires includes a conductive core comprising a first material and one or more insulating shell layers comprising a compositionally different second material disposed about the core. In one embodiment, a dielectric layer is disclosed comprising a substrate comprising an insulating material having a plurality of nanoscale pores defined therein having a pore diameter less than about 100 nm, and a conductive material disposed within the nanoscale pores.

Abstract: Among other things, one or more techniques and/or systems are disclosed for rendering query results. After a user submits a query, a plurality of query results may be received, comprising at least a first query result and a second query result. The first query result can be rendered in a first collapsed view, which may be smaller and may comprise less information than a full view of the first query result. Upon receiving a first indication of scrolling, hinting that the user may wish to view more results, the first query result can be rendered in a first expanded view, which may comprise a full view of the first query result. Further, upon receiving the first indication of scrolling, the second query result can be rendered in a second collapsed view. Rendering query results as provided herein allows a (limited) viewable area to be used in an efficient manner.

Abstract: A lacrimal insert such as a punctal plug may incorporate a balloon or other similar structure to facilitate anchoring of the punctal plug within the lacrimal canaliculus. The balloon may be inflated once it is positioned and deflated if removal is required or desired. The balloon may be affixed to an external portion of the punctal plug or incorporated into a chamber within the punctal plug.

Abstract: A system for use in presenting media content includes a media server configured to provide media content and a media client configured to obtain the media content from the media server and to present the media content on a device. The media client is configured to generate a first code and to transmit information to the media server. The information identifies the media client and the information indicates that the media client is available for pairing. The media server is configured to reply to the information with a second code that corresponds to the first code in order to enable pairing between the media server and the media client.

Abstract: Personal restraint systems for use in recreational utility vehicles (RUVs) are disclosed herein. A personal restraint system configured in accordance with one embodiment of the disclosure includes a web configured to extend around an occupant and a locking retractor having a motorized spool. A control module is electrically coupled to the locking retractor and the motorized spool is operably coupled to the web. A sensor is electrically coupled to the control module and is configured to detect dynamic characteristics of the RUV. In one embodiment, the sensor detects acceleration events that indicate a level of ride quality and the locking retractor adjusts the tension in the web based on the level of ride quality.

Abstract: In one embodiment, hybrid body armor includes a ballistic fabric and a plurality of small ballistic plates arranged in a tightly packed array over the ballistic fabric.

Abstract: A system for use in presenting media content includes a media server configured to provide media content and a media client configured to obtain the media content from the media server and to present the media content on a device. The media client is configured to generate a first code and to transmit information to the media server. The information identifies the media client and the information indicates that the media client is available for pairing. The media server is configured to reply to the information with a second code that corresponds to the first code in order to enable pairing between the media server and the media client.

Abstract: The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.

Abstract: Disclosed are lacrimal inserts and their method of use for delivery of of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye and is configured to release medication via a designated port, valve, or orifice in the insert housing and inhibits diffusion of medication via the housing itself The core may include retention features to ensure that it remains securely located within the lacrimal insert over its usable life.

Abstract: Bonnet apparatus to provide live-loading to a seal are described herein. An example bonnet assembly includes a housing having a recessed opening to define a shoulder and a sealing disc disposed within the recessed opening. A biasing element is disposed in the recessed opening between a flange of the sealing disc and the shoulder of the housing to provide a load to a seal to be disposed between the housing and the fluid device. The biasing element biases the sealing disc away from the housing and the biasing element enables the sealing disc to move within the recessed opening relative to the housing when the bonnet assembly is coupled to the fluid device.

Abstract: A method of treating a human subject with cancer is disclosed. A pharmaceutical composition is administered to the subject, the pharmaceutical composition comprising human leukocytes and a replication-competent oncolytic virus in suspension in a physiologically acceptable solution. Alternatively the pharmaceutical composition comprises human leukocytes or platelets infected with an oncolytic virus.

Abstract: Graded artificial dielectrics using nanostructures, such as nanowires, are disclosed. The graded artificial dielectric includes a material (typically a dielectric) with a plurality of nanostructures, such as nanowires, embedded within the dielectric material. One or more characteristics of the nanostructures are spatially varied from a first region within the dielectric to a second region within the dielectric to produce permittivity of the graded artificial dielectric that is spatially varied. The characteristics that can be varied include, but are not limited to, nanostructure density, nanostructure length, nanostructure aspect ratio, nanostructure oxide ratio, and nanostructure alignment. Methods of producing graded artificial dielectrics are also provided. A wide range of electronic devices such as antennas can use graded artificial dielectrics with nanostructures to improve performance.

Abstract: The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.

Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.

Abstract: Graded artificial dielectrics using nanostructures, such as nanowires, are disclosed. The graded artificial dielectric includes a material (typically a dielectric) with a plurality of nanostructures, such as nanowires, embedded within the dielectric material. One or more characteristics of the nanostructures are spatially varied from a first region within the dielectric to a second region within the dielectric to produce permittivity of the graded artificial dielectric that is spatially varied. The characteristics that can be varied include, but are not limited to, nanostructure density, nanostructure length, nanostructure aspect ratio, nanostructure oxide ratio, and nanostructure alignment. Methods of producing graded artificial dielectrics are also provided. A wide range of electronic devices such as antennas can use graded artificial dielectrics with nanostructures to improve performance.

Abstract: A mass and heat exchanger includes at least one first substrate with a surface for supporting a continuous flow of a liquid thereon that either absorbs, desorbs, evaporates or condenses one or more gaseous species from or to a surrounding gas; and at least one second substrate operatively associated with the first substrate. The second substrate includes a surface for supporting the continuous flow of the liquid thereon and is adapted to carry a heat exchange fluid therethrough, wherein heat transfer occurs between the liquid and the heat exchange fluid.