Patents by Inventor Jennifer Chew

Jennifer Chew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEOTIDE SEQUENCE GENERATION BY BARCODE BEAD-COLOCALIZATION IN PARTITIONS
    Publication number: 20230012786
    Abstract: Comparison of common sequencing reads from sequencing based on partition-based barcoding can be used to improve sequencing results. Increased loading of barcodes per partition can also improve sequencing results.
    Type: Application
    Filed: September 14, 2022
    Publication date: January 19, 2023
    Inventors: Ronald LEBOFSKY, Andrew KOHLWAY, Jennifer CHEW, Zachary BURKETT, Man CHENG
  • MULTIPLEX CAPTURE OF GENE AND PROTEIN EXPRESSION FROM A BIOLOGICAL SAMPLE
    Publication number: 20220389504
    Abstract: Provided herein are methods, compositions, and kits for preparing biological samples for multiplex spatial gene expression and proteomic analysis, such as determining a location of a nucleic acid analyte and a protein analyte in a biological sample.
    Type: Application
    Filed: July 18, 2022
    Publication date: December 8, 2022
    Inventors: Jennifer Chew, Joseph Francis Shuga, Patrick Roelli, Denise Cheung, Alexander Hermes, Yifeng Yin, Naishitha Anaparthy, Ryo Hatori, Marlon Stoeckius, Rapolas Spalinskas, Anna-Maria Katsori, Cedric Uytingco, Mesruh Turkekul, David Sukovich, Christina Galonska, Aleksandra Jurek, Octavian Marian Bloju
  • METHODS FOR DETERMINING A LOCATION OF A TARGET NUCLEIC ACID IN A BIOLOGICAL SAMPLE
    Publication number: 20220348992
    Abstract: The present disclosure relates to determining the location of analytes in fixed biological samples.
    Type: Application
    Filed: July 6, 2022
    Publication date: November 3, 2022
    Inventors: Marlon Stoeckius, James Michael Chell, Cedric Uytingco, Jennifer Chew, Felice Alessio Bava
  • Nucleotide sequence generation by barcode bead-colocalization in partitions
    Patent number: 11479816
    Abstract: Comparison of common sequencing reads from sequencing based on partition-based barcoding can be used to improve sequencing results. Increased loading of barcodes per partition can also improve sequencing results.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: October 25, 2022
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Ronald Lebofsky, Andrew Kohlway, Jennifer Chew, Zachary Burkett, Man Cheng
  • SPATIALLY-TAGGED ANALYTE CAPTURE AGENTS FOR ANALYTE MULTIPLEXING
    Publication number: 20220326251
    Abstract: Provided herein are methods for preparing biological samples for spatial proteomic analysis, methods of determining a location of a protein analyte in a biological sample, and methods of determining a location of a protein analyte and a nucleic acid analyte in a biological sample.
    Type: Application
    Filed: May 6, 2022
    Publication date: October 13, 2022
    Inventors: Cedric Uytingco, James Michael Chell, Marlon Stoeckius, Albert Kim, Dulce Ovando Morales, Andrej Hartnett, Yifeng Yin, Jennifer Chew
  • METHOD FOR RESETTING AN ARRAY
    Publication number: 20220098661
    Abstract: Provided herein are methods for resetting an array to which a biological sample has been applied that include treating the array with a set of biological sample removal conditions.
    Type: Application
    Filed: December 10, 2021
    Publication date: March 31, 2022
    Inventors: Jennifer Chew, Zachary Bent, Alvaro J. Gonzalez Lozano
  • METHODS FOR DETERMINING A LOCATION OF A BIOLOGICAL ANALYTE IN A BIOLOGICAL SAMPLE
    Publication number: 20220049293
    Abstract: Provided herein are methods of determining a location of a biological analyte in a biological sample.
    Type: Application
    Filed: December 6, 2019
    Publication date: February 17, 2022
    Applicant: 10x Genomics, Inc.
    Inventors: Lucas Frenz, Eswar Prasad Ramachandran Iyer, Tarjei Sigurd Mikkelsen, Preyas Shah, Katherine Pfeiffer, Yifeng Yin, Elliott Meer, Jessica Michele Terry, Yi Luo, Shalini Gohil, Joshua Delaney, Adam Lowe, Linda Kvastad, Eva Gracia Villacampa, Ludvig Larsson, Joakim Lundeberg, Zachary Bent, Meghan L. F. Frey, Jennifer Chew
  • IMAGING SYSTEM HARDWARE
    Publication number: 20220049294
    Abstract: A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.
    Type: Application
    Filed: December 6, 2019
    Publication date: February 17, 2022
    Applicant: 10x Genomics, Inc.
    Inventors: Cedric Uytingco, Zachary Bent, Eswar Prasad Ramachandran Iyer, Fernandino Valdecanas, Meghan L. F. Frey, Steven William Short, Yifeng Yin, Augusto Manuel Tentori, Rajiv Bharadwaj, David Maurice Cox, Jennifer Chew, Joakim Lundeberg, Felice Alessio Bava, Linda Kvastad, Andrew D. Price
  • Methods for Generating Spatially Barcoded Arrays
    Publication number: 20210324457
    Abstract: This disclosure relates to methods for generating spatially barcoded arrays using concentration gradients.
    Type: Application
    Filed: August 27, 2019
    Publication date: October 21, 2021
    Inventors: Eswar Prasad Ramachandran Iyer, Michael Schnall-Levin, Augusto Manuel Tentori, Tarjei Sigurd Mikkelsen, Benjamin Hindson, Michael Ybarra Lucero, Rajiv Bharadwaj, Yifeng Yin, Zachary Bent, Jennifer Chew, Meghan L. F. Frey, Linda Kvastad, Joakim Lundeberg, Eva Gracia Villacampa
  • BIOMARKERS OF BREAST CANCER
    Publication number: 20210199660
    Abstract: Provided herein are methods of determining a location of one or more analytes of interest in a cancer sample. Also provided herein are methods of detecting expression of one or more analytes in a cancer (e.g., breast cancer) sample. Further provided are methods of diagnosing and treating breast cancer.
    Type: Application
    Filed: November 20, 2020
    Publication date: July 1, 2021
    Inventors: Stephen R. Williams, Cedric Uytingco, Zachary Bent, Jennifer Chew
  • TRANSPOSASE-BASED GENOMIC ANALYSIS
    Publication number: 20210164036
    Abstract: The methods and reagents are provided for barcoding and analysis of DNA samples using partition (e.g., droplet) technology while avoiding performing amplification in droplets.
    Type: Application
    Filed: December 29, 2020
    Publication date: June 3, 2021
    Inventors: Ronald LEBOFSKY, Jennifer CHEW
  • Transposase-based genomic analysis
    Patent number: 10907205
    Abstract: The methods and reagents are provided for barcoding and analysis of DNA samples using partition (e.g., droplet) technology while avoiding performing amplification in droplets.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: February 2, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Ronald Lebofsky, Jennifer Chew
  • NUCLEOTIDE SEQUENCE GENERATION BY BARCODE BEAD-COLOCALIZATION IN PARTITIONS
    Publication number: 20200056231
    Abstract: Comparison of common sequencing reads from sequencing based on partition-based barcoding can be used to improve sequencing results. Increased loading of barcodes per partition can also improve sequencing results.
    Type: Application
    Filed: August 20, 2019
    Publication date: February 20, 2020
    Inventors: Ronald LEBOFSKY, Andrew KOHLWAY, Jennifer CHEW, Zachary BURKETT, Man CHENG
  • METHODS AND COMPOSITIONS FOR DECONVOLUTING PARTITION BARCODES
    Publication number: 20190241944
    Abstract: Methods of assessing whether multiple differently-barcodes primers are in partitions are provided.
    Type: Application
    Filed: January 29, 2019
    Publication date: August 8, 2019
    Inventors: Sean CATER, Lucas FRENZ, Andrew KOHLWAY, Jennifer CHEW, Rob RAY, Ronald LEBOFSKY
  • TRANSPOSASE-BASED GENOMIC ANALYSIS
    Publication number: 20190127792
    Abstract: The methods and reagents are provided for barcoding and analysis of DNA samples using partition (e.g., droplet) technology while avoiding performing amplification in droplets.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 2, 2019
    Inventors: Ronald Lebofsky, Jennifer Chew