Patents by Inventor Jennifer Iaci

Jennifer Iaci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of using chondroitinase ABCI mutants
    Patent number: 7722864
    Abstract: The present invention relates to protein and nucleic acid mutants of chondroitinase ABCI. Such chondroitinase ABCI mutant enzymes exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
    Type: Grant
    Filed: October 10, 2007
    Date of Patent: May 25, 2010
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Anthony O. Caggiano, Andrea Vecchione, Jennifer Iaci
  • COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS
    Publication number: 20090104176
    Abstract: One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 23, 2009
    Applicant: ACORDA THERAPEUTICS, INC.
    Inventors: Anthony O. Caggiano, Jennifer Iaci, Andrea Vecchione, Elizabeth Markensohn
  • Compositions and Methods of Using Chondroitinase ABCI Mutants
    Publication number: 20090060895
    Abstract: The present invention relates to protein and nucleic acid mutants of chondroitinase ABCI. Such chondroitinase ABCI mutant enzymes exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
    Type: Application
    Filed: October 10, 2007
    Publication date: March 5, 2009
    Inventors: Anthony O. Caggiano, Andrea Vecchione, Jennifer Iaci
  • Compositions and methods of using chondroitinase ABCI mutants
    Patent number: 7485295
    Abstract: One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
    Type: Grant
    Filed: September 26, 2006
    Date of Patent: February 3, 2009
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Anthony O. Caggiano, Jennifer Iaci, Andrea Vecchione, Elizabeth Markensohn
  • Fusion proteins for the treatment of CNS
    Publication number: 20090028829
    Abstract: This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activity of neuronal growth inhibitory molecules, as well as fusion proteins which includes a proteoglycan degrading domain and a domain capable of blocking and or over coming the activity of neuronal growth inhibitory molecules.
    Type: Application
    Filed: May 17, 2004
    Publication date: January 29, 2009
    Inventors: Elliott A. Gruskin, Anthony O. Caggiano, Gargi Roy, Jennifer Iaci, Michael P. Zimber
  • Compositions and Methods for Promoting Neuronal Outgrowth
    Publication number: 20070274979
    Abstract: Neural outgrowth in the central nervous system is achieved by administering chondroitinase AC and/or chondroitinase B to degrade chondroitin sulfate proteoglycans that inhibit or contribute to the inhibition of nervous tissue regeneration.
    Type: Application
    Filed: May 5, 2003
    Publication date: November 29, 2007
    Inventors: Elliott Gruskin, Jennifer Iaci, A.M. Vecchione, Sarah Kasperbauer, Gargi Roy
  • Compositions and methods of using chondroitinase ABCI mutants
    Publication number: 20070104703
    Abstract: One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
    Type: Application
    Filed: September 26, 2006
    Publication date: May 10, 2007
    Inventors: Anthony Caggiano, Jennifer Iaci, Andrea Vecchione, Elizabeth Markensohn