Patents by Inventor Jennifer L. Hillman

Jennifer L. Hillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel ATPase inhibitor
    Publication number: 20020098561
    Abstract: The invention provides a novel human ATPase inhibitor protein (HATPI) and polynucleotides which identify and encode HATPI. The invention also provides genetically engineered expression vectors and host cells containing the nucleic acid sequences encoding HATPI. The invention also provides pharmaceutical compositions containing HATPI or antagonists to HATPI, and in the use of these compositions for the treatment of diseases associated with the expression of HATPI. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HATPI for the treatment of diseases associated with the expression of HATPI. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding HATPI or anti-HATPI antibodies which specifically bind to HATPI.
    Type: Application
    Filed: October 9, 2001
    Publication date: July 25, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventor: Jennifer L. Hillman
  • Human citrate synthase homolog
    Publication number: 20020099195
    Abstract: The invention provides a human citrate synthase homolog (HUCS) and polynucleotides which identify and encode HUCS. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HUCS.
    Type: Application
    Filed: November 27, 2001
    Publication date: July 25, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Purvi Shah
  • Growth-associated protease inhibitor heavy chain precursor
    Publication number: 20020099178
    Abstract: The invention provides a human growth-associated protease inhibitor heavy chain precursor (GAPIP) and polynucleotides which identify and encode GAPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GAPIP.
    Type: Application
    Filed: April 5, 2001
    Publication date: July 25, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler, Chandra Patterson
  • Proteins associated with cell proliferation
    Publication number: 20020098569
    Abstract: The invention provides three human proteins associated with cell proliferation, referred to collectively as “APOP” and individually as “APOP-1”, “APOP-2”, and “APOP-3”, and polynucleotides which identify and encode APOP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of APOP.
    Type: Application
    Filed: June 28, 2001
    Publication date: July 25, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Preeti Lal, Purvi Shah, Neil C. Corley
  • Rab proteins
    Publication number: 20020090712
    Abstract: The present invention provides three Rab proteins (designated individually as HRABS-1, HRABS-2, and HRABS-3, and collectively as HRABS) and polynucleotides which identify and encode HRABS. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HRABS and a method for producing HRABS. The invention also provides for use of HRABS and agonists, antibodies, or antagonists specifically binding HRABS, in the prevention and treatment of diseases associated with expression of HRABS. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HRABS for the treatment of diseases associated with the expression of HRABS. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HRABS.
    Type: Application
    Filed: November 19, 2001
    Publication date: July 11, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli, Olga Bandman
  • Human tumor suppressor polypeptides
    Publication number: 20020091249
    Abstract: The present invention provides a human tumor suppressor (TUPRO-2) and polynucleotides which identify and encode TUPRO-2. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for treating diseases associated with expression of TUPRO-2.
    Type: Application
    Filed: October 3, 2001
    Publication date: July 11, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah
  • Human signal peptide-containing proteins
    Publication number: 20020091244
    Abstract: The invention provides a human signal peptide-containing proteins, the polynucleotides which encode them and methods for their use. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists.
    Type: Application
    Filed: March 5, 2001
    Publication date: July 11, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Susan K. Sather, Purvi Shah
  • Human ubiquitin-conjugating enzyme homologs
    Publication number: 20020086406
    Abstract: The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of UCEH.
    Type: Application
    Filed: August 14, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Mariah Baughn, Yalda Azimzai
  • Mitochondrial adenylate kinase
    Publication number: 20020086393
    Abstract: The present invention provides a human mitochondrial adenylate kinase (HMAK) and polynucleotides which encode HMAK. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HMAK.
    Type: Application
    Filed: December 4, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah
  • Ubiquitin-like conjugating protein
    Publication number: 20020086408
    Abstract: The invention provides a human ubiquitin-like conjugating protein (UBCLE) and polynucleotides which identify and encode UBCLE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of UBCLE.
    Type: Application
    Filed: December 7, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Neil C. Corley
  • Human apoptosis-related calcium-binding protein
    Publication number: 20020086830
    Abstract: The present invention provides a human apoptosis-related calcium-binding protein (HARC) and polynucleotides which identify and encode HARC. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HARC and a method for producing HARC. The invention also provides for agonists, antibodies, or antagonists specifically binding HARC, and their use, in the prevention and treatment of diseases associated with expression of HARC. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HARC for the treatment of diseases associated with the expression of HARC. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HARC.
    Type: Application
    Filed: October 1, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Human protease molecules
    Publication number: 20020086334
    Abstract: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
    Type: Application
    Filed: September 26, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Y. Tom Tang, Purvi Shah
  • Delta 1-pyrroline-5-carboxylate reductase homolog
    Publication number: 20020081691
    Abstract: The invention provides a human delta 1-pyrroline-5-carboxylate reductase homolog (P5CRH) and polynucleotides which identify and encode P5CRH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of P5CRH.
    Type: Application
    Filed: July 24, 2001
    Publication date: June 27, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Mariah R. Baughn
  • Human lysophospholipase
    Publication number: 20020081699
    Abstract: The present invention provides a human lysophospholipase (NHLP) and polynucleotides which identify and encode NHLP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing NHLP and for treating or preventing disorders associated with expression of NHLP.
    Type: Application
    Filed: November 19, 2001
    Publication date: June 27, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Lynn E. Murry
  • Human reticulocalbin isoforms
    Publication number: 20020081604
    Abstract: The invention provides two human reticulocalbin isoforms designated individually as RCN &ggr; and RCN &dgr; and collectively as RCN, and polynucleotides which identify and encode RCN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of RCN.
    Type: Application
    Filed: May 1, 2001
    Publication date: June 27, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Purvi Shah
  • Protein kinase homologs
    Publication number: 20020081290
    Abstract: The invention provides human protein kinase homologs (PKH) and polynucleotides which identify and encode PKH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PKH.
    Type: Application
    Filed: May 30, 2001
    Publication date: June 27, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone, Yalda Azimzai, Dyung Aina M. Lu
  • Novel human DBI/ACBP-like protein
    Publication number: 20020068825
    Abstract: The present invention provides polynucleotides which identify and encode a novel human Diazepam binding inhibitor/acyl-CoA binding protein (DBI/ACBP)-like protein (DBIH). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding DBIH. The invention also provides for the use of substantially purified DBIH for drug delivery as well as for the production of recombinant proteins for the treatment of diseases associated with the expression of DBIH. Additionally, the invention provides for the use of antisense molecules to DBIH in the treatment of diseases associated with the expression of DBIH. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotides which hybridize with naturally occurring sequences encoding DBIH and antibodies which specifically bind to the protein.
    Type: Application
    Filed: May 14, 2001
    Publication date: June 6, 2002
    Applicant: Incyte Pharmaceuticals, Inc
    Inventors: Janice Au-Young, Jennifer L. Hillman, Surya K. Goli
  • Human kallikrein
    Publication number: 20020068341
    Abstract: The present invention provides a human tumor suppressor (HKALL) and polynucleotides which identify and encode HKALL. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for treating diseases associated with expression of HKALL.
    Type: Application
    Filed: January 16, 2001
    Publication date: June 6, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal
  • Subunits of NADH dehydrogenase
    Patent number: 6399345
    Abstract: The present invention provides four NADH dehydrogenase subunits (designated individually as NDS-1, NDS-2, NDS-3, and NDS-4 and collectively as NDS) and polynucleotides which identify and encode NDS. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NDS and a method for producing NDS. The invention also provides for use of NDS and agonists, antibodies, or antagonists specifically binding NDS, in the prevention and treatment of diseases associated with expression of NDS. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NDS for the treatment of diseases associated with the expression of NDS. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NDS.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: June 4, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Surya K. Goli, Jennifer L. Hillman
  • Database for storage and analysis of full-length sequences
    Publication number: 20020064792
    Abstract: The present invention is a computerized storage and retrieval system for genetic information and related annotated information. The data of the system is stored in a relational database which interfaces with public databases to allow analysis both within the database of the invention and between information within that database and external public databases. The sequence data is edited before entry into the system, and is stored in a curated, functional clustering organization. The information associated with the data is stored in an expression database that is linked to the storage of the sequence data.
    Type: Application
    Filed: September 19, 2001
    Publication date: May 30, 2002
    Inventors: Stephen E. Lincoln, Tod M. Klingler, Janice Au-Young, Y. Tom Tang, Richard D. Goold, Ingrid E. Akerblom, Jeffrey J. Seilhamer, Phillip R. Hawkins, Lynn E. Murry, Angelo M. Delegeane, Wendy B. Levine, Jennifer L. Hillman, Surya K. Goli, Christina M. Altus, Olga Bandman, Samuel T. LaBrie, Purvi Shah