Patents by Inventor Jennifer L. Hillman

Jennifer L. Hillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human apoptosis regulator
    Patent number: 6307021
    Abstract: The present invention provides a human apoptosis regulator protein (APRG) and polynucleotides which identify and encode APRG. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding APRG and a method for producing APRG. The invention also provides for agonists, antibodies, or antagonists specifically binding APRG, and their use, in the prevention and treatment of diseases associated with expression of APRG. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding APRG for the treatment of diseases associated with the expression of APRG. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding APRG.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: October 23, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Surya K. Goli, Jennifer L. Hillman
  • Database for storage and analysis of full-length sequences
    Patent number: 6303297
    Abstract: The present invention is a computerized storage and retrieval system for genetic information and related annotated information. The data of the system is stored in a relational database which interfaces with public databases to allow analysis both within the database of the invention and between information within that database and external public databases. The sequence data is edited before entry into the system, and is stored in a curated, functional clustering organization. The information associated with the data is stored in an expression database that is linked to the storage of the sequence data.
    Type: Grant
    Filed: November 13, 1997
    Date of Patent: October 16, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Steve E. Lincoln, Tod M. Klingler, Janice Au-Young, Y. Tom Tang, Richard D. Goold, Ingrid E. Akerblom, Jeffrey J. Seilhamer, Phillip R. Hawkins, Lynn E. Murry, Angelo M. Delegeane, Wendy B. Levine, Jennifer L. Hillman, Surya K. Goli, Christina M. Altus, Olga Bandman, Samuel T. LaBrie, Purvi Shah
  • Rab proteins
    Patent number: 6300472
    Abstract: The invention provides three human Rab proteins (RABP) and polynucleotides which identify and encode RABP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of RABP.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: October 9, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Purvi Shah
  • Human membrane-spanning proteins
    Publication number: 20010025098
    Abstract: The invention provides a human membrane spanning proteins (MSPs) and polynucleotides which identify and encode MSPs. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of MSPs.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 27, 2001
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Olga Bandman, Preeti Lal, Jennifer L. Hillman, Henry Yue, Neil C. Corley, Karl J. Guegler, Matthew R. Kaser, Mariah R. Baughn, Purvi Shah
  • Human peroxisomal thioesterase
    Publication number: 20010024786
    Abstract: The invention provides a human peroxisomal thioesterase (PxTE) and polynucleotides which identify and encode PxTE. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PxTE.
    Type: Application
    Filed: January 18, 2001
    Publication date: September 27, 2001
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Neil C. Corley
  • Phospholipid transfer protein
    Patent number: 6287786
    Abstract: The invention provides a mammalian nucleic acid molecule and fragments thereof. It also provides for the use of the nucleic acid molecule for the characterization, diagnosis, or treatment of conditions, diseases and disorders associated with gene expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecule.
    Type: Grant
    Filed: July 31, 2000
    Date of Patent: September 11, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Matthew R. Kaser, Jennifer L. Hillman, Mariah R. Baughn
  • Human LEA-motif developmental protein
    Patent number: 6281190
    Abstract: The present invention provides a human LEA motif protein (HuLEAP) and polynucleotides which identify and encode HuLEAP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HuLEAP and a method for producing HuLEAP. The invention also provides for agonists, antibodies, or antagonists specifically binding HuLEAP, and their use, in the prevention and treatment of diseases associated with expression of HuLEAP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HuLEAP for the treatment of diseases associated with the expression of HuLEAP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HuLEAP.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: August 28, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Microtubule-associated protein
    Patent number: 6280733
    Abstract: The present invention provides a human microtubule-associated protein (hLC3) and the polynucleotides which identify and encode hLC3. The invention also provides genetically engineered expression vectors, host cells, and a method for producing hLC3. The invention also provides hLC3 as well as agonists, antibodies, and antagonists of hLC3, and the use thereof for the prevention and treatment of diseases associated with the expression of hLC3. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding hLC3 for the treatment of diseases associated with the expression of hLC3. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding hLC3.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: August 28, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Proteins associated with apoptosis
    Patent number: 6281334
    Abstract: The invention provides three human proteins associated with cell proliferation, referred to collectively as “APOP” and individually as “APOP-1”, “APOP-2”, and “APOP-3”, and polynucleotides which identify and encode APOP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of APOP.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: August 28, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Pretti Lal, Purvi Shah, Neil C. Corley
  • Phosphatidylinositol 4,5-bisphosphate 5-phosphatase
    Patent number: 6277373
    Abstract: The invention provides a human phosphatidylinositol 4,5-bisphosphate 5-phosphatase (PBPP) and polynucleotides which identify and encode PBPP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PBPP.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: August 21, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Purvi Shah
  • Nucleic acids encoding human ubiquitin-conjugating enzyme homologs
    Patent number: 6277568
    Abstract: The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists.
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: August 21, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Mariah Baughn, Yalda Azimzai
  • Human phosphodiesterase regulatory subunit
    Patent number: 6277377
    Abstract: The invention provides a new human phosphodiesterase regulatory subunit (HPRS) and polynucleotides which encode HPRS. The invention also provides expression vectors, host cells, agonists, the complement of the polynucleotide sequence and antibodies. The invention also provides methods for treating disorders associated with expression of HPRS.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: August 21, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Purvi Shah
  • Human NADH dehydrogenase subunits
    Patent number: 6277572
    Abstract: The present invention provides a human NADH-D protein subunit (NDS) and polynucleotides which encode NDS. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of NDS.
    Type: Grant
    Filed: December 9, 1998
    Date of Patent: August 21, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Preeti Lal
  • Calcium-binding protein
    Publication number: 20010012831
    Abstract: The present invention provides a human calcium-binding protein (HCBP) and polynucleotides which identify and encode HCBP. The invention also provides expression vectors and host cells, agonists, antibodies, and antagonists. In addition, the invention provides methods for producing HCBP and for treating or preventing disorders associated with the expression of HCBP.
    Type: Application
    Filed: January 23, 2001
    Publication date: August 9, 2001
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • NOVEL HUMAN PYROPHOSPHATASE
    Publication number: 20010010911
    Abstract: The present invention provides a human pyrophosphatase (HPYP) and polynucleotides which identify and encode HPYP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPYP and a method for producing HPYP. The invention also provides for use of HPYP and agonists, antibodies, or antagonists specifically binding HPYP, in the prevention and treatment of cancer and inflammatory diseases. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPYP for the treatment of diseases associated with the expression of HPYP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPYP.
    Type: Application
    Filed: October 8, 1999
    Publication date: August 2, 2001
    Inventors: PHILLIP R. HAWKINS, JENNIFER L. HILLMAN
  • Extracellular adhesive proteins
    Publication number: 20010010913
    Abstract: The invention provides human extracellular adhesive proteins (EXADH) and polynucleotides which identify and encode EXADH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of EXADH.
    Type: Application
    Filed: December 22, 2000
    Publication date: August 2, 2001
    Applicant: Incyte Pharmaceuticals, Inc
    Inventors: Jennifer L. Hillman, Henry Yue, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Delta 1-pyrroline-5-carboxylate reductase homolog
    Patent number: 6268192
    Abstract: The invention provides a human delta 1-pyrroline-5-carboxylate reductase homolog (P5CRH) and polynucleotides which identify and encode P5CRH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of P5CRH.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: July 31, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Mariah R. Baughn
  • Insulin receptor tyrosine kinase substrate
    Patent number: 6265550
    Abstract: The invention provides a human insulin receptor tyrosine kinase substrate (IRS-p53h) and polynucleotides which identify and encode IRS-p53h. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of IRS-p53h.
    Type: Grant
    Filed: March 15, 1999
    Date of Patent: July 24, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Purvi Shah
  • Protein kinase homologs
    Patent number: 6264947
    Abstract: The invention provides human protein kinase homologs (PKH) and polynucleotides which identify and encode PKH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PKH.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: July 24, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone, Yalda Azimzai, Dyung Aina M. Lu
  • Glutathione s-transferase
    Patent number: 6248325
    Abstract: The present invention provides a human glutathione s-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HGST and a method for producing HGST. The invention also provides for agonists, antibodies, or antagonists specifically binding HGST, and their use, in the prevention and treatment of cancer and other diseases associated with the expression of HGST. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HGST for the treatment of cancer and other diseases associated with the expression of HGST. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HGST.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: June 19, 2001
    Assignee: Incyte Genomics
    Inventors: Surya K. Goli, Jennifer L. Hillman