Patents by Inventor Jens Fischer

Jens Fischer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190382489
    Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.
    Type: Application
    Filed: December 18, 2018
    Publication date: December 19, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: JOERG BENZ, LAURA CODARRI DEAK, STEFAN DENGL, SEBASTIAN FENN, JENS FISCHER, GUY GEORGES, CHRISTIAN KLEIN, VIKTOR LEVITSKI, VALERIA LIFKE, OLIVER PLOETTNER, STEFAN SEEBER, BARBARA WEISER, ILDIKO WUENSCHE, ADRIAN ZWICK
  • Publication number: 20190366941
    Abstract: The invention relates to a motor vehicle (1) having a device (2) for airborne sound acoustic sensing of the surroundings of the motor vehicle (1), wherein the device (2) comprises at least one microphone (3), which is integrated in a body part (4) or in an attachment part (5) of the motor vehicle (1). According to the invention, at least one opening (6) is formed in the body component (4) or in the attachment part (5) for the entry of sound waves and at least one film (7) or membrane is arranged in the region of the opening (6).
    Type: Application
    Filed: November 13, 2017
    Publication date: December 5, 2019
    Inventors: Michael Fischer, Stephan Berneke, Jens Koenig, Manuel Stoll, Udo Hermann
  • Publication number: 20190322748
    Abstract: The invention relates to bispecific antibodies comprising a first antigen-binding site that specifically binds to PD1 and a second antigen-binding site that specifically binds to TIM3, in particular to bispecific antibodies, wherein the bispecific antibody binds to 5 TIM3 with a lower binding affinity when compared to the binding to PD1. The invention further relates to methods of producing these molecules and to methods of using the same.
    Type: Application
    Filed: March 27, 2019
    Publication date: October 24, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: LAURA CODARRI-DEAK, GEORG FERTIG, JENS FISCHER, CHRISTIAN KLEIN, VIKTOR LEVITSKI, VALERIA LIFKE, MARIO PERRO, JOERG THOMAS REGULA, TILMAN SCHLOTHAUER, STEFAN SEEBER, PABLO UMANA, ILDIKO WUENSCHE, ADRIAN ZWICK
  • Patent number: 10434184
    Abstract: The invention provides anti-TPBG antibodies and methods of using the same.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: October 8, 2019
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Stefan Dengl, Sebastian Fenn, Jens Fischer, Thomas Friess, Sabine Imhof-Jung, Ben-Fillippo Krippendorff, Christian Schantz, Tilman Schlothauer, Claudio Sustmann, Barbara Weiser, Adrian Zwick
  • Patent number: 10364928
    Abstract: A resonator (1) has at least first and second annular chambers (2, 3, 17) arranged between inlet and outlet pieces (22, 21). An inner pipe (4) extends between the inlet piece (22) and the outlet piece (21) and has wall holes (23) that connect to the annular chambers (2, 3, 17). The first annular chamber (2) has a U-shaped circumferential wall (6) coaxial to the resonator longitudinal axis (5) and transitions at both ends to engage the inner pipe (4). The second annular chamber (3) has an L-shaped circumferential wall (12) coaxial to the resonator longitudinal axis (5). An end of the L-shaped circumferential wall remote from the first annular chamber (2) transitions into a cylindrical end piece (13), and an opposite end of the L-shaped circumferential wall lies on part of the outer wall (9) of the first annular chamber (2) extending parallel to the resonator longitudinal axis (5).
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: July 30, 2019
    Assignees: UMFOTEC GMBH
    Inventors: Andre Grieswald, Jens Fischer
  • Patent number: 10329346
    Abstract: Bispecific tetravalent antibodies against IL-17 and TNFa, useful in therapy, e.g. the treatment of rheumatoid arthritis and other autoimmune diseases and/or to reduce pathological inflammatory conditions.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: June 25, 2019
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Johannes Auer, Martin Bader, Jens Fischer, Stefan Lorenz, Joerg Moelleken, Stefan Seeber
  • Publication number: 20190153091
    Abstract: Herein is reported a co-cultivation system for co-cultivating a pool of rabbit B-cells or single deposited rabbit B-cells wherein cells CD40L expressing CHO cells are used as feeder in the presence of IL-2 and IL-21.
    Type: Application
    Filed: October 3, 2018
    Publication date: May 23, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Josef Endl, Jens Fischer, Peter Kern, Sonja Offner, Josef Platzer, Stefan Seeber
  • Patent number: 10287352
    Abstract: The invention relates to bispecific antibodies comprising a first antigen-binding site that specifically binds to PD1 and a second antigen-binding site that specifically binds to TIM3, in particular to bispecific antibodies, wherein the bispecific antibody binds to TIM3 with a lower binding affinity when compared to the binding to PD1. The invention further relates to methods of producing these molecules and to methods of using the same.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: May 14, 2019
    Assignee: HOFFMAN-LA ROCHE INC.
    Inventors: Laura Codarri-Deak, Georg Fertig, Jens Fischer, Christian Klein, Viktor Levitski, Valeria Lifke, Mario Perro, Joerg Thomas Regula, Tilman Schlothauer, Stefan Seeber, Pablo Umana, Ildiko Wuensche, Adrian Zwick
  • Publication number: 20180344869
    Abstract: The present invention relates to anti-brain target agents and therapeutic uses thereof.
    Type: Application
    Filed: May 16, 2018
    Publication date: December 6, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jens Fischer, Per-Ola Freskgard, Antonio Iglesias, Jens Niewoehner, Felix Weber
  • Publication number: 20180328920
    Abstract: Herein is reported a method for the determination of the simultaneous binding of a bispecific antibody to a first and a second antigen comprising the steps of a) incubating a cell expressing cell-membrane bound FRET-donor-tagged first antigen and FRET-acceptor-tagged second antigen with the bispecific antibody, and b) determining the simultaneous binding of the bispecific antibody by determining the energy transfer from the FRET-donor to the FRET-acceptor.
    Type: Application
    Filed: March 30, 2018
    Publication date: November 15, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Stefan SEEBER, Jens FISCHER, Georg FERTIG
  • Publication number: 20180326054
    Abstract: The invention relates to bispecific antibodies comprising a first antigen binding domain that specifically binds to PD1 and a second antigen binding domain that specifically binds to LAG3. The invention further relates to methods of producing these molecules and to methods of using the same.
    Type: Application
    Filed: April 3, 2018
    Publication date: November 15, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Laura Codarri Deak, Jens Fischer, Sabine Imhof-Jung, Christian Klein, Stefan Seeber, Patrick Alexander Aaron Weber
  • Publication number: 20180311371
    Abstract: The invention provides anti-TPBG antibodies and methods of using the same.
    Type: Application
    Filed: April 27, 2018
    Publication date: November 1, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Stefan DENGL, Sebastian FENN, Jens FISCHER, Thomas FRIESS, Sabine IMHOF-JUNG, Ben-Fillippo KRIPPENDORFF, Christian SCHANTZ, Tilman SCHLOTHAUER, Claudio SUSTMANN, Barbara WEISER, Adrian ZWICK
  • Publication number: 20180290913
    Abstract: The present invention relates to a process for producing a workpiece made of glass ceramics, and to the workpiece obtainable by the process according to the invention. Further, the invention relates to the use of the workpiece obtained as a dental restoration, and to a process allowing the translucency of a workpiece to be controlled.
    Type: Application
    Filed: October 18, 2016
    Publication date: October 11, 2018
    Inventors: Michael GÖDIKER, Berit MÜLLER, Jens FISCHER, Wolfgang RAUH
  • Patent number: 10040843
    Abstract: The present invention generally relates to fusion proteins of antibodies and interleukin-10 (IL-10). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: August 7, 2018
    Assignee: ROCHE GLYCART AG
    Inventors: Lydia Jasmin Duerner, Thomas Emrich, Jens Fischer, Ralf Hosse, Ekkehard Moessner, Pablo Umana, Daigen Xu
  • Patent number: 10018323
    Abstract: The invention relates to a vehicle headlight having at least one light source arrangement comprising a laser, and having a headlight lens comprising a body composed of a transparent material, wherein the body comprises at least one light tunnel and a light-conducting part having at least one optically active light exit surface, wherein the light tunnel comprises at least one, more particularly optically active, light entrance surface and undergoes transition with a bend into the light-conducting part for the purpose of imaging the bend as a bright-dark boundary by means of light coupled or radiated from the light source arrangement into the light entrance surface.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: July 10, 2018
    Assignee: Docter Optics SE
    Inventors: Dmitry Fedosik, Wolfram Wintzer, Jens Fischer
  • Patent number: 9924240
    Abstract: A method for animating a map resource is provided, the method includes receiving a plurality of Uniform Resource Locators (URLs) from a third party website, the plurality of URLs comprising one or more attributes; receiving a user selection to create an animation sequence of one or more of the attributes; querying a current value of the one or more attributes from an external resource and returning the queried value; receiving, from the user, a first keyframe and a second keyframe for the animation sequence; interpolating one or more additional keyframes with assigned values; and creating the animation sequence based on the first keyframe, the second keyframe, and the one or more additional keyframes.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: March 20, 2018
    Assignee: Google LLC
    Inventors: Patrick Ted Gert Blohmé, Christopher Michael Roush, Karl Henrik Olav Porseland, Michael William Tavendale, Mathias Paumgarten, Eric Henry Margusity, Wes Falik, Jens Fischer, Simon Frederick Cave, Israel Pastrana Vicente, Cornelis Antonius Plattel, Jonathan Patrick Brennan
  • Publication number: 20170247454
    Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.
    Type: Application
    Filed: September 29, 2016
    Publication date: August 31, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Joerg Benz, Laura Codarri Deak, Stefan Dengl, Sebastian Fenn, Jens Fischer, Guy Georges, Christian Klein, Viktor Levitski, Valeria Lifke, Oliver Ploettner, Stefan Seeber, Barbara Weiser, Ildiko Wuensche, Adrian Zwick
  • Patent number: 9714292
    Abstract: The present invention relates to Bispecific antibodies against human TWEAK and human IL17 (bispecific TWEAK-IL17 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: July 25, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Johannes Auer, Martin Bader, Jens Fischer, Hubert Kettenberger, Maximiliane Koenig, Stefan Lorenz, Joerg Moelleken
  • Publication number: 20170114135
    Abstract: The invention relates to bispecific antibodies comprising a first antigen-binding site that specifically binds to PD1 and a second antigen-binding site that specifically binds to TIM3, in particular to bispecific antibodies, wherein the bispecific antibody binds to TIM3 with a lower binding affinity when compared to the binding to PD1. The invention further relates to methods of producing these molecules and to methods of using the same.
    Type: Application
    Filed: September 29, 2016
    Publication date: April 27, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: LAURA CODARRI-DEAK, GEORG FERTIG, JENS FISCHER, CHRISTIAN KLEIN, VIKTOR LEVITSKI, VALERIA LIFKE, MARIO PERRO, JOERG THOMAS REGULA, TILMAN SCHLOTHAUER, STEFAN SEEBER, PABLO UMANA, ILDIKO WUENSCHE, ADRIAN ZWICK
  • Patent number: 9540084
    Abstract: A submarine is designed for combating oil when submerged. The submarine includes a snout (14, 36) which is conduit-connected to a conduit leading into the submarine. The snout (14, 36) is part of an oil suction device and/or part of a device for bringing out an oil decomposition substance. The snout (14) may be designed in a rigid manner and be pivotable from a position between a pressure hull (6) of the submarine and an outer hull (10) forming an upper deck (12) of the submarine, into a position outside the outer hull (10). The snout (36) may also be designed in a flexible manner, wherein the snout (36) is fastened in a section adjacent to a free end, on an ROV (40).
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: January 10, 2017
    Assignee: ThyssenKrupp Marine Systems GmbH
    Inventors: Hendrik Brandt, Jens Fischer