Patents by Inventor Jens Fischer

Jens Fischer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12275063
    Abstract: The disclosure provides for cleaning three-dimensional (3D) components printed in a powder bed from adhering powder particles. The 3D-printed components are cleaned with a negative pressure-induced volumetric flow. The 3D-printed components are first removed from the powder bed after their manufacture, then positioned on a feed device and moved together with the feed device into a pressure-tight sealable chamber. In the interior of the chamber negative pressure is subsequently built up and a fluid volumetric flow is applied to the 3D-printed component to be cleaned which results in the powder particles being detached from the 3D-printed component. The powder particles are removed from the sealed chamber in a pressure tight manner via at least one channel conduit which is subjected to negative pressure and are fed to a separation device. The chamber is subsequently released of pressure and then opened for removal of the cleaned 3D-printed component.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: April 15, 2025
    Assignee: ACTECH GmbH
    Inventors: Jens Fischer, Norbert Demarczyk, Hana Kästner Maxová
  • Patent number: 12258371
    Abstract: The invention relates autonomous VH domains (aVH) with cysteines in positions 52a and 71 or in positions 33 and 52 in order to stabilize the autonomous VH domains. Said cysteines are capable of forming a disulfide bond and/or form a disulfide bond under suitable conditions. The invention further relates to aVH libraries.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: March 25, 2025
    Assignee: Hoffman-La Roche Inc.
    Inventors: Laura Deak Codarri, Stefan Dengl, Jens Fischer, Thomas Hofer, Laurent Lariviere, Ekkehard Moessner, Stefan Seeber, Pablo Umana, Anne-Claire Zagdoun
  • Publication number: 20250060105
    Abstract: A combustor includes a wall that defines a combustor interior to receive a fluid. The combustor also includes a slot that extends through the wall. The combustor also includes a resonator coupled to the wall. The resonator includes a resonator box defining a resonator interior between the wall and the resonator box, and a resonator segment disposed within the resonator box. The resonator segment includes a resonator neck having a resonator inlet and resonator outlet, the resonator inlet positioned within the resonator interior, the resonator outlet in flow communication with the combustor interior through the slot. The resonator neck defines a nonlinear flow path between the resonator inlet and the resonator outlet.
    Type: Application
    Filed: August 9, 2024
    Publication date: February 20, 2025
    Inventors: Rajesh Rajaram, Sebastian Hermeth, Ayan Nath, Sebastian Pfadler, Peter Kaufmann, Jens Kleinfeld, Jens Fischer, Saurav Kumar Agarwal
  • Publication number: 20250051456
    Abstract: The present invention relates to anti-HLA-G antibodies and methods of using the same.
    Type: Application
    Filed: October 31, 2024
    Publication date: February 13, 2025
    Inventors: Stefan DENGL, Sebastian FENN, Jens FISCHER, Andreas HINZ, Claudia KIRSTENPFAD, Stefan KLOSTERMANN, Joerg MOELLEKEN, Georg TIEFENTHALER, Sabine HOVES, Alexander BUJOTZEK, Meher MAJETY
  • Publication number: 20250051455
    Abstract: The present invention relates to multispecific antibodies that bind to HLA-G ant to a T cell activating antigen, their preparation, formulations and methods of using the same.
    Type: Application
    Filed: July 15, 2024
    Publication date: February 13, 2025
    Inventors: Stefan DENGL, Sabastian FENN, Jens FISCHER, Claudia KIRSTENPFAD, Stefan KLOSTERMANN, Joerg MOELLEKEN, Georg TIEFENTHALER, Alexander BUJOTZEK, Meher MAJETY, Silke KIRCHNER
  • Patent number: 12157770
    Abstract: The present invention relates to anti-HLA-G antibodies and methods of using the same.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: December 3, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Stefan Dengl, Sebastian Fenn, Jens Fischer, Andreas Hinz, Claudia Kirstenpfad, Stefan Klostermann, Joerg Moelleken, Georg Tiefenthaler, Sabine Hoves, Alexander Bujotzek, Meher Majety
  • Publication number: 20240360208
    Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
    Type: Application
    Filed: December 8, 2023
    Publication date: October 31, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Guy GEORGES, Jens FISCHER, Lukasz KACPRZYK, Valeria RUNZA, Jasmin SYDOW-ANDERSEN, Cristina BERTINETTI-LAPATKI, Michael GERTZ, Shu FENG, Siok Wan GAN, Wei Shiong Adrian HO, Runyi Adeline LAM
  • Patent number: 12103967
    Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
    Type: Grant
    Filed: November 14, 2023
    Date of Patent: October 1, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jens Fischer, Guy Georges, Anton Jochner, Gregor Jordan, Hubert Kettenberger, Joerg Moelleken, Tilman Schlothauer, Georg Tiefenthaler, Valeria Runza, Meher Majety, Martin Schaefer, Maria Viert, Shu Feng, Wei Shiong Adrian Ho, Siok Wan Gan, Runyi Adeline Lam, Michael Gertz
  • Patent number: 12085252
    Abstract: The disclosure relates, inter alia, to a vehicle headlight (10), for example for a motor vehicle (1), wherein the vehicle headlight (10) comprises an illumination matrix (534) with a plurality of independently controllable illumination pixels for generating a (for example time-variant) illumination pattern, wherein the vehicle headlight (10) comprises an objective for imaging the illumination pattern, and wherein the objective comprises at least one objective lens.
    Type: Grant
    Filed: June 29, 2023
    Date of Patent: September 10, 2024
    Assignee: DOCTER OPTICS SE
    Inventors: Markus Winkler, Jens Fischer, Hagen Schweitzer
  • Publication number: 20240294642
    Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.
    Type: Application
    Filed: September 13, 2023
    Publication date: September 5, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Joerg BENZ, Laura CODARRI DEAK, Stefan DENGL, Sebastian FENN, Jens FISCHER, Guy GEORGES, Christian KLEIN, Viktor LEVITSKI, Valeria LIFKE, Oliver PLOETTNER, Stefan SEEBER, Barbara WEISER, Ildiko WUENSCHE, Adrian ZWICK
  • Patent number: 11981737
    Abstract: The present invention relates to anti-HLA-G antibodies and methods of using the same.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: May 14, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jens Fischer, Meher Majety, Stefan Dengl, Georg Tiefenthaler, Stefan Klostermann, Claudia Kirstenpfad, Esther Koenigsberger, Francesca Ros
  • Publication number: 20240117029
    Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
    Type: Application
    Filed: November 14, 2023
    Publication date: April 11, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jens FISCHER, Guy GEORGES, Anton JOCHNER, Gregor JORDAN, Hubert KETTENBERGER, Joerg MOELLEKEN, Tilman SCHLOTHAUER, Georg TIEFENTHALER, Valeria RUNZA, Meher MAJETY, Martin SCHAEFER, Maria VIERT, Shu FENG, Wei Shiong Adrian HO, Siok Wan GAN, Runyi Adeline LAM, Michael GERTZ
  • Publication number: 20240083993
    Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
    Type: Application
    Filed: June 15, 2023
    Publication date: March 14, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jens FISCHER, Guy GEORGES, Anton JOCHNER, Gregor JORDAN, Hubert KETTENBERGER, Joerg MOELLEKEN, Tilman SCHLOTHAUER, Georg TIEFENTHALER, Valeria RUNZA, Meher MAJETY, Martin SCHAEFER, Maria VIERT, Shu FENG, Wei Shiong Adrian HO, Siok Wan GAN, Runyi Adeline LAM, Michael GERTZ
  • Publication number: 20240011616
    Abstract: The disclosure relates, inter alia, to a vehicle headlight (10), for example for a motor vehicle (1), wherein the vehicle headlight (10) comprises an illumination matrix (534) with a plurality of independently controllable illumination pixels for generating a (for example time-variant) illumination pattern, wherein the vehicle headlight (10) comprises an objective for imaging the illumination pattern, and wherein the objective comprises at least one objective lens.
    Type: Application
    Filed: June 29, 2023
    Publication date: January 11, 2024
    Applicant: Docter Optics SE
    Inventors: Markus WINKLER, Jens FISCHER, Hagen SCHWEITZER
  • Publication number: 20240002506
    Abstract: The present invention relates to anti-LAG3 antibodies, to methods of producing these molecules and methods of using the same.
    Type: Application
    Filed: June 20, 2023
    Publication date: January 4, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Laura CODARRI DEAK, Stefan C. DENGL, Jens FISCHER, Christian KLEIN, Stefan SEEBER, Patrick Alexander Aaron WEBER, Adrian ZWICK
  • Publication number: 20230399396
    Abstract: Herein is reported a co-cultivation system for co-cultivating a pool of rabbit B-cells or single deposited rabbit B-cells wherein cells CD40L expressing CHO cells are used as feeder in the presence of TL-2 and TL-21.
    Type: Application
    Filed: August 11, 2022
    Publication date: December 14, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Josef Endl, Jens Fischer, Peter Kern, Sonja Offner, Josef Platzer, Stefan Seeber
  • Publication number: 20230340081
    Abstract: The invention provides anti-S-HBs antibodies and methods of using the same.
    Type: Application
    Filed: June 8, 2021
    Publication date: October 26, 2023
    Inventors: Maryline BOURGINE, Maxime BERETTA, Hugo MOUQUET, Verena HEHLE, Stanislas POL, Hélène STRICK-MARCHAND, Malika AIT-GOUGHOULTE, Nadège PELLETIER, Jens FISCHER, Guy GEORGES, Tilman SCHLOTHAUER, Erwin VAN PUIJENBROEK, Wouter DRIESSEN
  • Patent number: 11739142
    Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: August 29, 2023
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jens Fischer, Guy Georges, Anton Jochner, Gregor Jordan, Hubert Kettenberger, Joerg Moelleken, Tilman Schlothauer, Georg Tiefenthaler, Valeria Runza, Meher Majety, Martin Schaefer, Maria Viert, Shu Feng, Wei Shiong Adrian Ho, Siok Wan Gan, Runyi Adeline Lam, Michael Gertz
  • Publication number: 20230183349
    Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.
    Type: Application
    Filed: March 3, 2023
    Publication date: June 15, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Joerg BENZ, Laura CODARRI DEAK, Stefan DENGL, Sebastian FENN, Jens FISCHER, Guy GEORGES, Christian KLEIN, Viktor LEVITSKI, Valeria LIFKE, Oliver PLOETTNER, Stefan SEEBER, Barbara WEISER, Ildiko WUENSCHE, Adrian ZWICK
  • Publication number: 20230135966
    Abstract: The disclosure provides for cleaning three-dimensional (3D) components printed in a powder bed from adhering powder particles. The 3D-printed components are cleaned with a negative pressure-induced volumetric flow. The 3D-printed components are first removed from the powder bed after their manufacture, then positioned on a feed device and moved together with the feed device into a pressure-tight sealable chamber. In the interior of the chamber negative pressure is subsequently built up and a fluid volumetric flow is applied to the 3D-printed component to be cleaned which results in the powder particles being detached from the 3D-printed component. The powder particles are removed from the sealed chamber in a pressure tight manner via at least one channel conduit which is subjected to negative pressure and are fed to a separation device. The chamber is subsequently released of pressure and then opened for removal of the cleaned 3D-printed component.
    Type: Application
    Filed: March 23, 2021
    Publication date: May 4, 2023
    Inventors: Jens FISCHER, Norbert DEMARCZYK, Hana KÄSTNER MAXOVÁ