Patents by Inventor Jens Larsen

Jens Larsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ACTIVE BALANCING VALVE FOR A REFRIGERATION AND/OR AIR-CONDITIONING APPLICATION
    Publication number: 20240142021
    Abstract: An active balancing valve for a refrigeration and/or air-conditioning application having a valve housing with an inlet orifice, an outlet orifice and a mounting portion, a main valve element with a main pressure balance orifice and a control element at least partially defining a pressure balance passage. Each element is slidable inside the valve housing and comprises a control surface for controlling a fluid flow between the inlet orifice and the outlet orifice. The control element closes the main pressure balance orifice of the main valve element in a closed state of the valve.
    Type: Application
    Filed: September 14, 2021
    Publication date: May 2, 2024
    Inventors: Sigurd LARSEN, Jens Boesen PAWLIK, Clemens FOCK
  • Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
    Patent number: 11866445
    Abstract: The present invention relates to novel substituted dihydrothienopyrimidines with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: January 9, 2024
    Assignee: UNION therapeutics A/S
    Inventor: Jens Larsen
  • SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20220362259
    Abstract: The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Application
    Filed: June 10, 2021
    Publication date: November 17, 2022
    Inventors: Xifu LIANG, Jens LARSEN, Simon Feldbaek NIELSEN, Peter ANDERSEN
  • SUBSTITUTED DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20220281889
    Abstract: The present invention relates to novel substituted dihydrothienopyrimidines with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Application
    Filed: May 16, 2022
    Publication date: September 8, 2022
    Inventor: Jens LARSEN
  • Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
    Patent number: 11365204
    Abstract: The present invention relates to novel substituted dihydrothienopyrimidines with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: June 21, 2022
    Assignee: Union therapeutics A/S
    Inventor: Jens Larsen
  • SPORTS SHOOTING TARGET AND CORRESPONDING LAUNCHING DEVICE AND APPARATUSES
    Publication number: 20220178661
    Abstract: The invention relates to a sports shooting target made of a biodegradable material, the target having a rotational axis (z) and attachment means (2, 4?, 4?, 10, 11, 15) for releasable attachment to a launching device, where the target is provided with trajectory stabilizing means that are configured to stabilize the trajectory of the target by gyro effect caused by rotation about said rotational axis (z) which stabilizing means further function as propelling means that cause forward movement of the target along its trajectory due to the rotation about said rotational axis (z), when the target is rotating, where said stabilizing means comprises a fan comprising fan blades (3?, 3?) that rotates in unison with the target, when the target rotates, such that the stabilizing means both provides said stabilizing gyro effect and forward propulsion (movement) of the target along a chosen trajectory.
    Type: Application
    Filed: April 6, 2020
    Publication date: June 9, 2022
    Inventor: Jens Larsen
  • Substituted tetrahydropyran dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
    Patent number: 11299497
    Abstract: The present invention relates to novel substituted tetrahydropyran dihydrothienopyrimidines with phosphodiesterase inhibitory activity, and to their use in therapy, and to pharmaceutical compositions comprising the compounds and to methods of treating diseases with the compounds (I).
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: April 12, 2022
    Assignee: UNION therapeutics A/S
    Inventors: Jens Larsen, Simon Feldbaek Nielsen, Peter Andersen
  • Substituted azetidine dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
    Patent number: 11292799
    Abstract: The present invention relates to novel substituted azetidine dihydrothienopyrimidines with phosphodiesterase inhibitory activity, and to their use in therapy, and to pharmaceutical compositions comprising the compounds and to methods of treating diseases with the compounds (I).
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: April 5, 2022
    Assignee: UNION THERAPEUTICS A/S
    Inventors: Mark Andrews, Daniel Rodriguez Greve, Jens Larsen
  • Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors
    Patent number: 11065257
    Abstract: The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: July 20, 2021
    Assignee: LEO Pharma A/S
    Inventors: Xifu Liang, Jens Larsen, Simon Feldbaek Nielsen, Peter Andersen
  • SUBSTITUTED AZETIDINE DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20210070769
    Abstract: The present invention relates to novel substituted azetidine dihydrothienopyrimidines with phosphodiesterase inhibitory activity, and to their use in therapy, and to pharmaceutical compositions comprising the compounds and to methods of treating diseases with the compounds (I).
    Type: Application
    Filed: December 14, 2018
    Publication date: March 11, 2021
    Inventors: Mark ANDREWS, Daniel Rodriguez GREVE, Jens LARSEN
  • Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors
    Patent number: 10906915
    Abstract: The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: February 2, 2021
    Assignee: LEO Pharma A/S
    Inventors: Xifu Liang, Jens Larsen, Simon Feldbaek Nielsen, Peter Andersen
  • SUBSTITUTED TETRAHYDROPYRAN DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20200385400
    Abstract: The present invention relates to novel substituted tetrahydropyran dihydrothienopyrimidines with phosphodiesterase inhibitory activity, and to their use in therapy, and to pharmaceutical compositions comprising the compounds and to methods of treating diseases with the compounds (I).
    Type: Application
    Filed: December 14, 2018
    Publication date: December 10, 2020
    Inventors: Jens LARSEN, Simon Feldbaek NIELSEN, Peter ANDERSEN
  • SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20200323869
    Abstract: The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Application
    Filed: December 12, 2017
    Publication date: October 15, 2020
    Applicant: LEO Pharma A/S
    Inventors: Xifu LIANG, Jens LARSEN, Simon Feldbaek NIELSEN, Peter ANDERSEN
  • Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors
    Patent number: 10793580
    Abstract: The present invention relates to novel pyrazoloazepin-8-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: October 6, 2020
    Assignee: LEO Pharma A/S
    Inventors: Xifu Liang, Jens Larsen
  • SUBSTITUTED DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20200239493
    Abstract: The present invention relates to novel substituted dihydrothienopyrimidines with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Application
    Filed: September 20, 2018
    Publication date: July 30, 2020
    Inventor: Jens LARSEN
  • Amino-imidazopyridine derivatives as Janus kinase inhibitors and pharmaceutical use thereof
    Patent number: 10703751
    Abstract: The present invention relates to a compound according to formula (I) or pharmaceutically acceptable salts, hydrates, or solvates thereof; wherein R1 is C1-alkyl, R2 is C1-alkyl, R3 is C2-alkyl, R4 is hydrogen, R5 is hydrogen. The invention relates further to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to said compounds for use in the treatment autoimmune diseases and to intermediates for the preparation of said compounds.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: July 7, 2020
    Assignee: Leo Pharma A/S
    Inventors: Jens Larsen, Mogens Larsen, Lars Kyhn Rasmussen, Andreas Ritzen, Tine Marianne Duus
  • SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20200010477
    Abstract: The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Application
    Filed: December 12, 2016
    Publication date: January 9, 2020
    Inventors: Xifu LIANG, Jens LARSEN, Simon Feldbaek NIELSEN, Peter ANDERSEN
  • NOVEL AMINO-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE INHIBITORS AND PHARMACEUTICAL USE THEREOF
    Publication number: 20190367512
    Abstract: The present invention relates to a compound according to formula (I) or pharmaceutically acceptable salts, hydrates, or solvates thereof; wherein R1 is C1-alkyl, R2 is C1-alkyl, R3 is C2-alkyl, R4 is hydrogen, R5 is hydrogen. The invention relates further to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to said compounds for use in the treatment autoimmune diseases and to intermediates for the preparation of said compounds.
    Type: Application
    Filed: January 10, 2018
    Publication date: December 5, 2019
    Inventors: Jens LARSEN, Mogens LARSEN, Lars Kyhn RASMUSSEN, Andreas RITZEN, Tine Marianne DUUS
  • SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20190330223
    Abstract: The present invention relates to novel pyrazoloazepin-8-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Application
    Filed: December 12, 2016
    Publication date: October 31, 2019
    Inventors: Xifu LIANG, Jens LARSEN
  • Method for the production of shaped articles from reaction-bonded, silicon-infiltrated silicon carbide and/or boron carbide and thus produced shaped body
    Patent number: 9695089
    Abstract: Method for producing shaped bodies from reaction-bonded, silicon-infiltrated silicon carbide and/or boron carbide, characterized in that a monolithic preliminary body is built up in layers using a formless granulation to which a physical or chemical hardening or melt process is applied, wherein the granulation has a weight fraction of at least 95% silicon carbide and/or boron carbide with an average grain size of 70 to 200 ?m, the so-created preliminary body is impregnated at least once by the introduction of a carbon black suspension or via a gas-phase separation and secondary silicon carbide is created in contact with liquid or gaseous silicon by a subsequent reaction firing that solidifies an engagement composite produced.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: July 4, 2017
    Assignee: Schunk Ingenieurkeramik GmbH
    Inventors: Arthur Lynen, Jens Larsen, Michael Clemens