Abstract: A secondary battery comprising a positive electrode current collector, a first positive electrode mixture layer disposed on the positive electrode current collector and including a first positive electrode active material and a binder, and a second positive electrode mixture layer disposed on the first positive electrode mixture layer and including a second positive electrode active material and a binder. A nickel content of the second positive electrode active material is 80% by weight or less of a nickel content of the first positive electrode active material. By providing a secondary battery including a positive electrode of a multi-layer structure that includes positive electrode active materials having different contents of nickel, a secondary battery capable of improving high-temperature characteristics while maintaining energy density may be provided.

Abstract: An anode active material composition for a lithium secondary battery includes a carbon-based anode active material and a silicon-based anode active material, wherein the carbon-based anode active material has an orientation (I004/I110, here, I004 is a peak intensity of the (004) plane when measuring X-ray diffraction (XRD) of the carbon-based anode active material, and I110 is a peak intensity of the (110) plane when measuring XRD of the carbon-based anode active material) of 2.85 or less measured by XRD.

Abstract: An anode for a lithium secondary battery includes an anode current collector, a second anode active material layer disposed on the anode current collector and including a second anode active material that includes a graphite-based active material and composite particles, and a first anode active material layer disposed between the anode current collector and the second anode active material layer and including a first anode active material that includes a graphite-based active material and does not include the composite particles. Each of the composite particles includes a carbon-based particle including pores, a silicon-containing coating layer disposed on an inside of the pores of the carbon-based particle or on a surface of the carbon-based particle, and a surface oxide layer disposed on the silicon-containing coating layer and including a silicon oxide.

Abstract: An anode for a lithium secondary battery includes a anode current collector, a first anode mixture layer disposed on at least one surface of the anode current collector and including a first carbon-based active material and a silicon-based active material including a porous structure, and a second anode mixture layer disposed on the first anode mixture layer and including a second carbon-based active material and a silicon-based active material doped with magnesium.

Abstract: In a floating gate semiconductor nanostructure biosensor and a method for manufacturing the biosensor, the nanostructure biosensor includes a substrate, an insulating layer, a nanostructure, a source electrode and a drain electrode, a floating gate and a biological sensing material. The insulating layer is formed on the substrate. The nanostructure is protruded from the insulating layer. The source electrode and the drain electrode are formed on the insulating layer and dispose the nanostructure therebetween. The floating gate has a metal pattern or a polysilicon pattern, and extends with contacting the nanostructure. The biological sensing material has a first end combined with an immobile molecule on the floating gate, and a second end combined with a bio molecule.

Abstract: An anode for a lithium secondary battery includes an anode current collector, and an anode active material layer formed on at least one surface of the anode current collector. The anode active material layer includes an anode active material and an anode binder. The anode active material includes a plurality of composite particles, each of the composite particles include a silicon-based active material particle, and a solid electrolyte interphase (SEI) layer formed on at least a portion of a surface of the silicon-based active material particle. A relative standard deviation of thickness values of the SEI layer of the composite particles, which are measured by an X-ray photoelectron spectroscopy (XPS) from 9 different composite particles among the plurality of composite particles after repeating 100 cycles of charging and discharging is 20% or less.

Abstract: An anode for a lithium secondary battery includes a anode current collector, a first anode mixture layer disposed on at least one surface of the anode current collector and including a first carbon-based active material and a silicon-based active material including a porous structure, and a second anode mixture layer disposed on the first anode mixture layer and including a second carbon-based active material and a silicon-based active material doped with magnesium.

Abstract: Provided is a novel bacterial strain Bacteroides vulgatus MGM001 (Bacteroides vulgatus MGM001) and its use. The LPS from the strain of the subject matter has cytotoxicity weaker than the conventional ones and shows synergistic effect on the inhibition of biofilm formation when used in combination with LTA.

Abstract: A secondary battery comprising a positive electrode current collector, a first positive electrode mixture layer disposed on the positive electrode current collector and including a first positive electrode active material and a binder, and a second positive electrode mixture layer disposed on the first positive electrode mixture layer and including a second positive electrode active material and a binder. A nickel content of the second positive electrode active material is 80% by weight or less of a nickel content of the first positive electrode active material. By providing a secondary battery including a positive electrode of a multi-layer structure that includes positive electrode active materials having different contents of nickel, a secondary battery capable of improving high-temperature characteristics while maintaining energy density may be provided.

Abstract: The present disclosure provides an anode for a secondary battery, the anode including: an anode current collector; a first anode mixture layer provided on at least one surface of the anode current collector; a second anode mixture layer provided on the first anode mixture layer; and a third anode mixture layer provided on the second anode mixture layer, wherein each of the anode mixture layers includes a Si-containing anode active material and carbon nanotubes, and the number of walls of each of first carbon nanotubes included in the first anode mixture layer, second carbon nanotubes included in the second anode mixture layer, and third carbon nanotubes included in the third anode mixture layer satisfies a relation of [first carbon nanotubes<second carbon nanotubes<third carbon nanotubes].

Abstract: The present invention relates to use of a fusion protein of a therapeutic enzyme and an immunoglobulin Fc region in the prevention or improvement of renal diseases caused by or accompanied by Fabry disease.

Abstract: The present disclosure relates to a multilayer electrode for a secondary battery. The multilayer electrode for a secondary battery includes: an electrode current collector; a first mixture layer including an active material, a binder, and a single-walled carbon nanotube, the first mixture layer being formed on at least one surface of the electrode current collector; and a second mixture layer including an active material, a binder, and a multi-walled carbon nanotube, the second mixture layer being formed on the first mixture layer. According to the present disclosure, by improving the uniformity of the distribution of the conductive material in the electrode mixture layer, it is possible to prevent the resistance from increasing, and as a result, it is possible to improve the output characteristics of the secondary battery.

Abstract: Provided is use of a trigonal agonist having activities to all of glucagon, GLP-1, and GIP receptors, and/or a conjugate thereof in the prevention or treatment of sequelae following respiratory infectious diseases.

Abstract: Provided is a pharmaceutical composition for preventing or treating lupus-associated disease, including a glucagon/GLP-1/GIP triple agonist, a pharmaceutically acceptable salt thereof, a solvate thereof, or a long-acting conjugate thereof.

Abstract: Provided is a pharmaceutical composition for preventing or treating lupus-associated disease, including a GIP derivative, a pharmaceutically acceptable salt or solvate thereof, or a long-acting conjugate thereof.

Abstract: New therapeutic uses of a triple agonist and/or a long-acting conjugate thereof are disclosed. The triple agonist and/or a long-acting conjugate thereof acts on all of glucagon, GLP-1 and GIP receptors, and is useful in treating multiple sclerosis. Thus, patients' options can be broadened by expanding the category of drugs applicable to multiple sclerosis and patients' convenience can be increased by significantly increasing blood half-life.

Abstract: New therapeutic uses of a triple agonist and/or a long-acting conjugate thereof are disclosed. The triple agonist and/or a long-acting conjugate thereof acts on all of glucagon receptor, glucagon-like peptide-1 (GLP-1) receptor, and glucose-dependent insulinotropic polypeptide (GIP) receptor, and is useful in treating neurodegenerative diseases. Thus, patients’ options can be broadened by expanding the category of drugs applicable to applicable to neurodegenerative diseases, and can increase convenience for patients by significantly increasing blood half-life.

Abstract: A cathode for a lithium secondary battery based on the disclosed technology includes: a cathode current collector; and a cathode active material layer including a first cathode active material layer and a second cathode active material layer sequentially laminated on the cathode current collector, wherein the first cathode active material layer and the second cathode active material layer include first cathode active material particles and second cathode active material particles having different particle structures from each other in crystallography or morphology, and a mixing weight ratio of the second cathode active material particles to the first cathode active material particles in the first cathode active material layer may be different from a mixing weight ratio of the second cathode active material particles to the first cathode active material particles in the second cathode active material layers.

Abstract: According to an exemplary embodiment, there is provided a secondary battery in which a value of K1 represented by the following Expression (1) is 130 to 270: (200*AR+CR+20*CIR)*(1+CA)/CP??(1) in Expression (1), AR is a bulk resistance (?·cm) of the anode, CR is a bulk resistance (?·cm) of the cathode, CIR is an interfacial resistance (?·cm2) between the cathode active material layer and the cathode current collector, CP is 1?D/4.7, D is a pressed density (g/cc) of the cathode, and CA is an adhesive force (N/18 mm) between the cathode active material layer and the cathode current collector.

Abstract: A bulk acoustic resonator package includes a substrate, a cap, and first and second bulk acoustic resonators each including a first electrode, a piezoelectric layer, and a second electrode stacked in a direction in which the substrate and the cap face each other, and disposed between the substrate and the cap, wherein the first and second bulk acoustic resonators form a bandwidth based on first and second resonant frequencies different from each other and first and second antiresonant frequencies different from each other, a difference between the first and second resonant frequencies exceeds 200 MHz, the first bulk acoustic resonator is disposed closer to the substrate than to the cap, and the second bulk acoustic resonator is disposed closer to the cap than to the substrate.