Abstract: Provided are multivalent pneumococcal conjugate compositions comprising 22-27 different pneumococcal capsular polysaccharide-protein conjugates, wherein each pneumococcal capsular polysaccharide-protein conjugate comprises a protein carrier conjugated to a capsular polysaccharide from a different serotype of Streptococcus pneumoniae, wherein the Streptococcus pneumoniae CA serotypes are selected from 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10 A, 11 A, 12F, 14, 15A, 15B, 15C, 18C, 19A, 19F, 22F, 23 A, 23B, 23F, 24F, 33F, and 35B. Also provided are methods of producing the multivalent pneumococcal conjugate compositions and methods of using the same for prophylaxis against Streptococcus pneumoniae infection or disease in a subject. Also provided are immunogenic compositions comprising at least one polysaccharide-protein conjugate wherein the polysaccharide is a capsular polysaccharide from CN Streptococcus pneumoniae serotype 15A, 15C, 23 A, 23B, 24F, and/or 35B and methods of preparing the same.

Abstract: A deposition method may include: providing a structure to be deposited that includes a silicon oxide area and a silicon nitride area having different surface characteristics from each other; and performing an atomic layer deposition (ALD) process in a reactor provided with the structure to selectively form a silicon oxide layer on the silicon oxide portion between the silicon oxide portion and the silicon nitride portion. The ALD process may include: supplying a silicon precursor into the reactor to selectively adsorb the silicon precursor to a surface of the silicon oxide portion; purging the reactor; supplying an inhibitor material into the reactor to selectively adsorb the inhibitor material to a surface of the silicon nitride portion; purging the reactor; supplying an oxygen-containing source into the reactor; and purging the reactor.

Abstract: Disclosed is the game apparatus using a train device constituted by cars of different sizes. The play ball lowered along the lane assembly may enter any one of the cars. Depending on the car into which the play ball enters, a predetermined reward may be provided to the player. The play ball entering the car deviates through the opening and rises through the elevating device. The raised play ball may be waited to descend again through the lane assembly.

Abstract: The present disclosure provides a pharmaceutical composition for preventing or treating sepsis or septic shock comprising P1P or a derivative thereof. The present composition improves the survival rate of mice with sepsis induced by LPS or CLP treatment, as well as reduces the secretion of cytokines. Further, it helps to enhance the proliferation and function of vascular endothelial cells and increases the expression of SIRT1 protein which decreases in a sepsis patient. Accordingly, it can be effectively used in the treatment of sepsis.

Abstract: The present invention provides a Streptomyces sp. SNC087 strain (KCCM12505P) that is isolated from seawater and produces staurosporine, a method for producing staurosporine using the same, a method for culturing the same, and a pure culture medium of the same.

Abstract: Provided is a switching control method for an isolated bidirectional DC-DC converter, wherein the isolated bidirectional DC-DC converter connected between a DC grid system and a battery uses multiple switching controls together depending on a voltage of the battery, thereby facilitating high efficiency control. In the isolated bidirectional DC-DC converter according to the present invention, switching of a first switching unit and a second switching unit is controlled to control the flow of power by changing the bidirectional DC-DC voltage between the DC grid system and the battery, and the first and the second switching unit are switched using PSM switching control, SPWM switching control, and DPWM switching control together depending on a voltage with which the battery is charged and load capacity, thereby enhancing efficiency of the system.

Abstract: Provided is a switching control method for an isolated bidirectional DC-DC converter, wherein the isolated bidirectional DC-DC converter connected between a DC grid system and a battery uses multiple switching controls together depending on a voltage of the battery, thereby facilitating high efficiency control. In the isolated bidirectional DC-DC converter according to the present invention, switching of a first switching unit and a second switching unit is controlled to control the flow of power by changing the bidirectional DC-DC voltage between the DC grid system and the battery, and the first and the second switching unit are switched using PSM switching control, SPWM switching control, and DPWM switching control together depending on a voltage with which the battery is charged and load capacity, thereby enhancing efficiency of the system.

Abstract: The present invention relates to a real-time monitoring system and a real-time monitoring method for agriculture and livestock farming by using an IoT sensor, which are implemented in the agriculture and livestock farming to use the IoT sensor to detect a tag attached to a moving object and a Wi-Fi signal, and to use a livestock monitoring system (LMS) to monitor access to a virtual fence and an abnormal behavior of the moving object, and includes: generating a tag/Wi-Fi signal by a tag/Wi-Fi signal generator installed on a moving object; detecting, by an IoT sensor, the tag/Wi-Fi signal generated by the tag/Wi-Fi signal generator; and receiving, by an LMS unit, the tag/Wi-Fi signal detected by the IoT sensor to monitor access to a virtual fence and an abnormal behavior of the moving object.

Abstract: A bidirectionally open sunroof structure includes rail assemblies installed at both sides of a roof panel, a front tilt lever connected to a front glass and the rail assembly and located at a front part of the front glass, a rear tilt lever connected to the front glass and the rail assembly and located at a rear part of the front glass, a front sled located on the front glass and driven by a driving motor to slidably reciprocate along the rail assemblies, and a rear sled located on a rear glass and driven by a driving motor to slidably reciprocate along the rail assemblies. The rail assembly includes a first guide rail configured to slidably move the front sled therealong, and a second guide rail located within the first guide rail and configured to slidably move the rear sled therealong.

Abstract: The present invention relates to a detoxifying composition containing a new green extract, which is a medicinal herb, as an active ingredient. Thus, toxicities in the human body can be efficiently removed without side effects by activating an enzyme necessary for detoxification.

Abstract: A bidirectionally open sunroof structure includes rail assemblies installed at both sides of a roof panel, a front tilt lever connected to a front glass and the rail assembly and located at a front part of the front glass, a rear tilt lever connected to the front glass and the rail assembly and located at a rear part of the front glass, a front sled located on the front glass and driven by a driving motor to slidably reciprocate along the rail assemblies, and a rear sled located on a rear glass and driven by a driving motor to slidably reciprocate along the rail assemblies. The rail assembly includes a first guide rail configured to slidably move the front sled therealong, and a second guide rail located within the first guide rail and configured to slidably move the rear sled therealong.

Abstract: Provided are a substrate processing apparatus and a substrate processing method using the same and, more particularly, a substrate processing apparatus capable of controlling deposition of a reactive-metal-containing precursor in an exhaust line, and a substrate processing method using the same.

Abstract: The present disclosure relates to an active sonar system including a transmitter; a transducer; and an impedance matching circuit, and a method of estimating an equivalent model parameter of a multi-mode transducer, wherein an electrical equivalent model parameter having a plurality of stages corresponding to each mode is estimated by estimating an individual mode impedance and a total mode impedance from multi-mode impedance data and obtaining an interference amount of adjacent modes, and an equivalent model modeled thereby for which an interference effect by a multi-mode is taken into consideration is used for the design of an impedance matching circuit to minimize actual model fabrication and effectively derive detailed design elements and the like, thereby allowing an integrated circuit design with peripheral electronic units for interfacing the sonar system.

Abstract: The present invention relates to a detoxifying composition containing a new green extract, which is a medicinal herb, as an active ingredient. Thus, toxicities in the human body can be efficiently removed without side effects by activating an enzyme necessary for detoxification.

Abstract: Disclosed herein are a radiographic imaging apparatus and a method of controlling the radiographic imaging apparatus. The radiographic imaging apparatus may include an imager configured to image a subject to obtain image data; a real-time processor configured to communicate with the imager and configured to obtain a real-time processing authority and perform real-time image processing on the image data; and a non-real-time processor configured to communicate with the imager and configured to perform non-real-time image processing on the image data, and in response to a failure occurring in the real-time processor, obtain the real-time processing authority and perform the real-time image processing on the image data.

Abstract: Disclosed are monomeric avidin-like proteins with a strong and stable biotin-binding ability, protein conjugates containing two or more of the monomeric avidin-like proteins and having a multivalent binding ability to biotin, nucleic acid molecules for encoding the monomeric avidin-like proteins, and methods for producing the monomeric avidin-like proteins, so the monomeric avidin-like proteins, due to the monomeric structure, are free from a problem of the disruption of receptor functions, caused by oligomerization occurring in existing tetrameric streptavidin or tetrameric but monovalent streptavidin variants.

Abstract: Provided are a substrate processing apparatus and a substrate processing method using the same and, more particularly, a substrate processing apparatus capable of controlling deposition of a reactive-metal-containing precursor in an exhaust line, and a substrate processing method using the same.

Abstract: Provided is an accommodating device for accommodating a different type of material and opening an accommodating part via a main body. The accommodating part, which is sealed, is disposed around a container spout part and coupled to the container spout part in a discharge direction of a material contained in the container and includes a storage space having a separate storage function. While the main body is disposed around the container spout part coupled to the accommodating part and is coupled to the container spout part, the storage space disposed in the accommodating part is opened to perform a dropping and mixing process in a storage space disposed in the container.

Abstract: The present invention relates to a detoxifying composition containing a new green extract, which is a medicinal herb, as an active ingredient. Thus, toxicities in the human body can be efficiently removed without side effects by activating an enzyme necessary for detoxification.

Abstract: A rear wheel steering system may include: a vehicle speed detection unit configured to detect a vehicle speed; a steering angle detection unit configured to detect a steering angle based on an operation of a steering wheel; a pinion angle detection unit configured to detect a pinion angle based on an operation of the steering wheel; a rear wheel driving unit configured to steer rear wheels; and a control unit configured to receive the vehicle speed, the steering angle, and the pinion angle from the vehicle speed detection unit, the steering angle detection unit, and the pinion angle detection unit, calculate a target rear wheel steering angle for steering the rear wheels, calculate a final rear wheel steering angle at which a steering point of the rear wheels is adjusted using a steering angle speed, the vehicle speed, and the pinion speed, and operate the rear wheel driving unit.