Patents by Inventor Jeremy I. Levin

Jeremy I. Levin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5298517
    Abstract: This disclosure describes novel imidazole compounds having the formula: ##STR1## wherein R.sup.1 and R.sup.6 are described in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: October 7, 1993
    Date of Patent: March 29, 1994
    Assignee: American Cyanamid Company
    Inventor: Jeremy I. Levin
  • Patent number: 5294611
    Abstract: The invention provides novel 2,3,6 substituted quinazolinones having the formula: ##STR1## wherein R.sup.6, R and X are as described in the specification, which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: March 15, 1994
    Assignee: American Cyanamid Company
    Inventors: Aranapakam M. Venkatesan, Jeremy I. Levin
  • Patent number: 5294617
    Abstract: This disclosure describes novel 2, 3, 6 substituted quinazolinones having the formula ##STR1## wherein R.sup.6, X and R are defined in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: March 15, 1994
    Assignee: American Cyanamid Company
    Inventors: Aranapakam M. Venkatesan, Jeremy I, Levin
  • Patent number: 5292734
    Abstract: This disclosure describes novel 2, 3, 6 substituted quinazolinones having the formula: ##STR1## wherein X, R, and R.sup.6 are described in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: March 8, 1994
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan
  • Patent number: 5292742
    Abstract: The invention provides novel 2,3,6-substituted quinazolinones having the formula ##STR1## wherein X, R, R.sup.6 are described in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: March 8, 1994
    Assignee: American Cyanamid Company
    Inventors: Aranapakam M. Venkatesan, Jeremy I. Levin
  • Patent number: 5290780
    Abstract: Novel quinazolinone compounds of the formula: ##STR1## wherein R.sup.5, R.sup.6, R.sup.7, R.sup.8, R and X are defined in the specification, which have angiotensin II (AII) antagonizing activity, intermediates useful in the preparation of the compounds, methods of producing and using the compounds to alleviate angiotensin induced hypertension and treat congestive heart failure in mammals.
    Type: Grant
    Filed: January 14, 1992
    Date of Patent: March 1, 1994
    Assignee: American Cyanamid Co.
    Inventors: Aranapakam Venkatesan, Jeremy I. Levin
  • Patent number: 5286729
    Abstract: The invention provides novel 2,3,6 substituted quinazolinones having the formula ##STR1## wherein R, R.sup.5, R.sup.6, R.sup.7, R.sup.8 and X are described in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: February 15, 1994
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan
  • Patent number: 5284852
    Abstract: This disclosure describes novel 2,3,6-substituted quinazolinones having the formula: ##STR1## wherein R.sup.6, X and R are as described in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: February 8, 1994
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan
  • Patent number: 5284853
    Abstract: The invention provides novel 2, 3, 6 substituted quinazolinones of the formula ##STR1## wherein, R, R.sup.6 and X are defined in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: February 8, 1994
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan
  • Patent number: 5281604
    Abstract: The invention provides novel 2,3,6 substituted quinazolinones of the formula ##STR1## wherein X, R and R.sup.6 are defined in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: January 25, 1994
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan
  • Patent number: 5281603
    Abstract: The invention provides novel 2,3,6-substituted quinazolinones having the formula ##STR1## wherein R.sup.6 is ##STR2## and X, R, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.8 are described in the specification which have activity as angiotensin II (AII) antagonists.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: January 25, 1994
    Assignee: American Cyanamid Company
    Inventors: Aranapakam M. Venkatesan, Jeremy I. Levin
  • Patent number: 5104869
    Abstract: Renin inhibiting compounds containing a single .alpha.-amino acid of the formula: ##STR1## and analogs thereof which inhibit the substrate-cleaving acting or renin, pharmaceutical compositions containing these compounds, processes for producing the compounds and methods of treating hypertension which employ the novel renin inhibitors.
    Type: Grant
    Filed: October 25, 1990
    Date of Patent: April 14, 1992
    Assignee: American Cyanamid Company
    Inventors: Jay D. Albright, Charles Frederick, Jeremy I. Levin, Fuk-Wah Sum, Marvin F. Reich
  • Patent number: 5084457
    Abstract: This invention is compounds of the formula: ##STR1## and a method of treating cognitive and related neuronal behavioral problems in mammals using the compounds.
    Type: Grant
    Filed: July 23, 1990
    Date of Patent: January 28, 1992
    Assignee: American Cyanamid Company
    Inventors: William J. Fanshawe, Joseph W. Epstein, Jeremy I. Levin
  • Patent number: 5013737
    Abstract: Novel 2,4,8-trisubstituted-3H,6H-1,4,5a,8a-tetraazaacenaphthylene-3,5 (4H)-diones and 2,4,8-trisubstituted-4,5-dihydro-5-thioxo-3H, 6H-1,4,5a,8a-tetra-azaacenaphthylen-3-ones are disclosed which are useful antihypertensive and anxiolytic agents.
    Type: Grant
    Filed: February 21, 1990
    Date of Patent: May 7, 1991
    Assignee: American Cyanamid Company
    Inventors: Shin S. Tseng, Joseph W. Epstein, Jeremy I. Levin
  • Patent number: 4916137
    Abstract: This disclosure described novel 5-(substituted-amino)-8-(substituted-phenyl)-3H,6H, -1,-4,5a,8a-tetraazaacenaphthylen-3-ones useful for the treatment of cognitive and related neural behavioral disorders in mammals.
    Type: Grant
    Filed: November 30, 1988
    Date of Patent: April 10, 1990
    Assignee: American Cyanamid Company
    Inventors: Joseph W. Epstein, Jeremy I. Levin, Shin S. Tseng
  • Patent number: 4904658
    Abstract: Substituted-6H,8H-pyrimido[1,2,3-cd]purine-8,10(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones which are useful as cognition enhancing agents, anxiolytic agents and/or antihypertensive agents in the treatment of cognitive and relative neutral behavioral problems, anxiety and hypertension in mammals.
    Type: Grant
    Filed: April 15, 1988
    Date of Patent: February 27, 1990
    Assignee: American Cyanamid Company
    Inventors: Shin S. Tseng, Joseph W. Epstein, Jeremy I. Levin