Abstract: Disclosed are various embodiments for synchronizing application state information across devices. More specifically, embodiments of the disclosure are related to resolving conflicts between application state information. A synchronization rule, an event name and/or event value are embedded within application state information obtained from devices associated with a user, from which conflicts can be resolved by an application synchronization service.

Abstract: A method comprises selecting a set of governance, risk management and compliance rules, designing a layout for a mobile application, customizing data sources and permissions for the mobile application based on the set of governance, risk management and compliance rules, and building the mobile application. The selecting, designing, customizing and building are performed by at least one processing device. The governance rules comprise a set of policies which define a structure by which a given entity is directed and managed. The risk management rules comprise a set of business processes and tolerances defining an unacceptable potential for loss for the set of business processes. The compliance rules comprise a set of procedures for conforming to the governance and risk management rules.

Abstract: A method is described for controlling a plurality of parallel-connected power converters 20a, 20b, each of which operates in accordance with a pulse width modulation (PWM) strategy defined by an independent voltage carrier signal and an independently controllable modulating sinusoidal voltage signal which are used to generate a PWM command signal for each PWM strategy. The voltage carrier signals of the PWM strategies have the same switching period and desynchronisation of the PWM command signals causes an unwanted circulating current to flow between the power converters 20a, 20b. The method thus comprises providing the independently controllable modulating sinusoidal voltage signal of the PWM strategy of at least one of the plurality of power converters 20a, 20b with a dc voltage offset to modify the PWM command signal of the at least one power converter and thereby increase the synchronisation of the PWM command signals so that the magnitude of any unwanted circulating current is reduced.

Abstract: Provided herein are polypeptides having ketol-aid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways.

Abstract: One embodiment includes an integrated circuit including an input circuit, a first diode including a first anode and a first cathode, with the first cathode coupled to a first voltage, the first anode coupled to the input circuit at a node via a first mechanical switch, a second diode including a second anode and a second cathode, with the second cathode coupled to the node via a second mechanical switch, the second anode coupled to a ground and a resistor coupled to the input circuit between the integrated circuit and the node, wherein in a first mode of operating, the first mechanical switch and the second mechanical switch are conducting, and in a second mode of operating, the first and second mechanical switches are nonconducting.

Abstract: An electrochemical fuel cell having an anode, an ion transfer membrane and a cathode has liquid water delivered to the fluid flow channels within the cathode so as to maintain a relative humidity of 100% throughout the fluid flow channels. A calibration method and apparatus is described for determining an optimum quantity or range of quantities of liquid water to be delivered to the cathode fluid flow channels under varying operating conditions. An operating method and apparatus is described that ensures an optimum quantity of liquid water is delivered to the cathode fluid flow channels under varying operating conditions.

Abstract: A fuel cell assembly provides for the delivery of fluid into a channel of a fluid flow field plate in alternating flow directions through the channel for delivery of the fluid to a membrane-electrode assembly. The fuel cell includes a fluid flow field plate having a channel for delivery of fluid to a membrane-electrode assembly, the channel having a first inlet/outlet port communicating therewith and a second inlet/outlet port communicating therewith; and a fluid delivery system connected to the fluid flow field plate adapted for bi-directional delivery of fluid into the channel of the fluid flow field plate.

Abstract: The present invention relates to methods for promoting dispersal of, or preventing formation of microbial biofilms, comprising: exposing a biofilm to an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent; treating a surface or medium susceptible to biofilm formation with an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent; incorporating an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent in a surface or medium susceptible to biofilm formation; or inducing the accumulation of one or more reactive oxygen or nitrogen species within microorganisms within said biofilm or capable of forming a biofilm. The invention also relates to methods for maintaining or enhancing or maintaining and enhancing the functioning of a biofilm, comprising exposing a biofilm to at least one nitric oxide scavenger, at least one antioxidant or at least one nitric oxide scavenger and at least one antioxidant.

Abstract: Methods, computer systems, and computer program products for antibody engineering. A variant set for an antibody of interest is constructed by identifying, using a plurality of rules, a plurality of positions in the antibody of interest and, for each respective position in the plurality of positions, substitutions for the respective position. The plurality of positions and the substitutions for each respective position in the plurality of position collectively define an antibody sequence space. A variant set comprising a plurality of variants of the antibody is selected. A property of all or a portion of the variants in the variant set is measured. A sequence-activity relationship is modeled between (i) one or more substitutions at one or more positions of the antibody of interest represented by the variant set and (ii) the property measured for all or the portion of the variants in the variant set.

Abstract: A rim seal assembly includes an annular seal element circumscribing an engine centerline or axis and mounted on an annular platform including a radially inwardly extending annular platform flange disposed between and connected to forward and aft flanges at distal ends of forward and aft annular elements respectively. Annular forward and aft outer rim cavities radially disposed between the forward and aft annular elements and the platform are axially separated by the platform flange. Cooling slots extend radially across axially facing forward and aft surfaces of the forward and aft flanges. The platform flange and the forward and aft flanges are bolted together. The annular seal element may include seal teeth in sealing relationship with an annular seal land such as in a labyrinth seal. The rim seal assembly may be incorporated in a low pressure turbine use a compressor as a source of cooling air.

Abstract: An electrochemical fuel cell having an anode, an ion transfer membrane and a cathode has liquid water delivered to the fluid flow channels within the cathode so as to maintain a relative humidity of 100% throughout the fluid flow channels. A calibration method and apparatus is described for determining an optimum quantity or range of quantities of liquid water to be delivered to the cathode fluid flow channels under varying operating conditions. An operating method and apparatus is described that ensures an optimum quantity of liquid water is delivered to the cathode fluid flow channels under varying operating conditions.

Abstract: An electrochemical fuel cell having an anode, an ion transfer membrane and a cathode has liquid water delivered to the fluid flow channels within the cathode so as to maintain a relative humidity of 100% throughout the fluid flow channels. A calibration method and apparatus is described for determining an optimum quantity or range of quantities of liquid water to be delivered to the cathode fluid flow channels under varying operating conditions. An operating method and apparatus is described that ensures an optimum quantity of liquid water is delivered to the cathode fluid flow channels under varying operating conditions.

Abstract: A method is described for controlling a plurality of power converters 1, 2 connected in parallel between an ac arrangement 12 and a common dc link 16, each of the power converters 1, 2 operating in accordance with a pulse width modulation (PWM) strategy and having an independently variable dc link reference voltage. The method comprises modifying an output voltage droop characteristic of at least one of the plurality of parallel-connected power converters 1, 2 by varying the dc link reference voltage of the at least one power converter 1, 2 based on the output current of the at least one power converter 1, 2 and the average of the output currents of the plurality of power converters 1, 2.

Abstract: One embodiment includes an integrated circuit including an input circuit, a first diode including a first anode and a first cathode, with the first cathode coupled to a first voltage, the first anode coupled to the input circuit at a node via a first mechanical switch, a second diode including a second anode and a second cathode, with the second cathode coupled to the node via a second mechanical switch, the second anode coupled to a ground and a resistor coupled to the input circuit between the integrated circuit and the node, wherein in a first mode of operating, the first mechanical switch and the second mechanical switch are conducting, and in a second mode of operating, the first and second mechanical switches are nonconducting.

Abstract: A method is described for controlling a plurality of parallel-connected power converters 20a, 20b, each of which operates in accordance with a pulse width modulation (PWM) strategy defined by an independent voltage carrier signal and an independently controllable modulating sinusoidal voltage signal which are used to generate a PWM command signal for each PWM strategy. The voltage carrier signals of the PWM strategies have the same switching period and desynchronisation of the PWM command signals causes an unwanted circulating current to flow between the power converters 20a, 20b. The method thus comprises providing the independently controllable modulating sinusoidal voltage signal of the PWM strategy of at least one of the plurality of power converters 20a, 20b with a dc voltage offset to modify the PWM command signal of the at least one power converter and thereby increase the synchronisation of the PWM command signals so that the magnitude of any unwanted circulating current is reduced.

Abstract: A rim seal assembly includes an annular seal element circumscribing an engine centerline or axis and mounted on an annular platform including a radially inwardly extending annular platform flange disposed between and connected to forward and aft flanges at distal ends of forward and aft annular elements respectively. Annular forward and aft outer rim cavities radially disposed between the forward and aft annular elements and the platform are axially separated by the platform flange. Cooling slots extend radially across axially facing forward and aft surfaces of the forward and aft flanges. The platform flange and the forward and aft flanges are bolted together. The annular seal element may include seal teeth in sealing relationship with an annular seal land such as in a labyrinth seal. The rim seal assembly may be incorporated in a low pressure turbine use a compressor as a source of cooling air.

Abstract: Methods, computer systems, and computer program products for biopolymer engineering. A variant set for a biopolymer of interest is constructed by identifying, using a plurality of rules, a plurality of positions in the biopolymer of interest and, for each respective position in the plurality of positions, substitutions for the respective position. The plurality of positions and the substitutions for each respective position in the plurality of positions collectively define a biopolymer sequence space. A variant set comprising a plurality of variants of the biopolymer of interest is selected. A property of all or a portion of the variants in the variant set is measured. A sequence-activity relationship is modeled between (i) one or more substitutions at one or more positions of the biopolymer of interest represented by the variant set and (ii) the property measured for all or the portion of the variants in the variant set.

Abstract: Methods, computer systems, and computer program products for antibody engineering. A variant set for an antibody of interest is constructed by identifying, using a plurality of rules, a plurality of positions in the antibody of interest and, for each respective position in the plurality of positions, substitutions for the respective position. The plurality of positions and the substitutions for each respective position in the plurality of position collectively define an antibody sequence space. A variant set comprising a plurality of variants of the antibody is selected. A property of all or a portion of the variants in the variant set is measured. A sequence-activity relationship is modeled between (i) one or more substitutions at one or more positions of the antibody of interest represented by the variant set and (ii) the property measured for all or the portion of the variants in the variant set.

Abstract: One embodiment includes an integrated circuit including an input circuit, a first diode including a first anode and a first cathode, with the first cathode coupled to a first voltage, the first anode coupled to the input circuit at a node via a first mechanical switch, a second diode including a second anode and a second cathode, with the second cathode coupled to the node via a second mechanical switch, the second anode coupled to a ground and a resistor coupled to the input circuit between the integrated circuit and the node, wherein in a first mode of operating, the first mechanical switch and the second mechanical switch are conducting, and in a second mode of operating, the first and second mechanical switches are nonconducting.

Abstract: A process for making a compound of formula (I), which is useful as an intermediate to compounds which activate glucokinase, is described, (wherein P1, R1 and R2 are as defined in the description).