Abstract: Many embodiments described herein prevent an aged spirit from degrading due to the oxygen trapped in the headspace without the use of a pump. The aged spirit preservation system may have a cork with an open top, an open bottom, and a channel extending from the open top to the open bottom. The cork may be sized couple to an internal portion of a bottle. The system may even include a sealing device coupled to an outer portion of the cork between the open top and the open bottom. Additionally, the system may include a replaceable cartridge containing an adsorbent media, iron, a salt, and a color-changing indicator. Oxygen from the bottle may be allowed to enter the cartridge and react with the iron via a non-reversible reaction, thereby preventing the degradation of the spirit.

Abstract: An apparatus may control the power delivered from an AC power source to an electrical load, and may comprise a controllably conductive device. The apparatus may also comprise a controller that may be operatively coupled to a control input of the controllably conductive device. The apparatus may also include a first wireless communication circuit operable to communicate via a first protocol and to join a first wireless communication network operable to communicate via the first protocol. The first wireless communication circuit may be in communication with the controller. The controller may be operative to determine a first condition for communicating via the first protocol. The controller may also be operable to control the first wireless communication circuit to join the first wireless communication network upon the first condition being satisfied.

Abstract: Aspects of the disclosure relate to detecting and identifying malicious sites using machine learning. A computing platform may receive a uniform resource locator (URL). The computing platform may parse and/or tokenize the URL to reduce the URL into a plurality of components. The computing platform may identify human-engineered features of the URL. The computing platform may compute a vector representation of the URL to identify deep learned features of the URL. The computing platform may concatenate the human-engineered features of the URL to the deep learned features of the URL, resulting in a concatenated vector representation. By inputting the concatenated vector representation of the URL to a URL classifier, the computing platform may compute a phish classification score. In response to determining that the phish classification score exceeds a first phish classification threshold, the computing platform may cause a cybersecurity server to perform a first action.

Abstract: Compounds that inhibit HIF-2?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2?.

Abstract: Compounds that inhibit HIF-2?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2?.

Abstract: Compounds that inhibit PI3K?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by PI3K?.

Abstract: An optical transformer includes a light source and an array of photovoltaic cells optically coupled to the light source, where at least a portion of the photovoltaic cells are connected in series. An optical connector such as a waveguide or an optical fiber may be disposed between an output of the light source and an input of the array of photovoltaic cells. Configured to generate a high voltage output, the optical transformer may be configured to power a device such as an actuator that provides a tunable displacement as a function of voltage.

Abstract: An apparatus may control the power delivered from an AC power source to an electrical load, and may comprise a controllably conductive device. The apparatus may also comprise a controller that may be operatively coupled to a control input of the controllably conductive device. The apparatus may also include a first wireless communication circuit operable to communicate via a first protocol and to join a first wireless communication network operable to communicate via the first protocol. The first wireless communication circuit may be in communication with the controller. The controller may be operative to determine a first condition for communicating via the first protocol. The controller may also be operable to control the first wireless communication circuit to join the first wireless communication network upon the first condition being satisfied.

Abstract: Devices, systems and methods for controlling the temperature of all or part of the body of a human or animal subject.

Abstract: A temperature management system for ease and timing of priming, setup and/or operation by a user. The temperature management system is configured to control a temperature of a patient's body using a heat exchange device. The temperature management system includes a console that is coupled to a heat exchange device, such as a catheter or surface pad. The console includes a hardware interface for receiving or coupling to a fluid loop configured to supply the heat exchange device with heating or cooling working fluid (e.g., saline). The interface provides instructions, indicators, and/or hardware elements to assist a user in configuring and priming the fluid loop for operation.

Abstract: A temperature management system is configured to control a temperature of a patient's body using a heat exchange device. The temperature management system is configured to deliver temperature management treatment or therapy to a patient. A user interface of the system is configured to display operational data and patient data on the user interface in a configuration that allows a user to determine or review one or more periods of the performed temperature management treatment.

Abstract: A peristaltic pump has an arcuate raceway with a partially concave inner surface extending through an arc of at least one hundred eighty degrees (180°). The arc defines a midpoint, and a rotor faces the inner surface of the raceway and is both rotatable relative to the raceway and translationally movable relative to the raceway between a pump position, wherein the rotor is spaced from the midpoint a first distance, and a tube load position, wherein the rotor is spaced from the midpoint a second distance greater than the first distance. A rotor motor is coupled to the rotor to rotate the rotor and rollers arranged on the rotor to contact tubing disposed between the rotor and the raceway when the rotor is in the pump position. A loading motor moves the rotor toward and away from the raceway.

Abstract: In one aspect, a wall panel is provided that includes a cross laminated timber panel, a first extrusion, and a second extrusion. The cross laminated timber panel includes a top side, a bottom side, a first side, and a second side. The panel also includes a notch in the bottom side and a T-flange on the top side. A wall system is provided comprising a plurality of wall panels. A method of installing the wall panel system is also provided.

Abstract: A device for dispensing a material having: a first surface with an orifice; a second surface opposite the first surface; a first endface comprising an annular opening; a second endface opposite the first endface; a cavity defined by the above. An actuator is anchored to the second surface and has at least a portion of a pressing pad extending through the orifice in the first surface. An inner side of the second surface comprises a contoured portion within the cavity, the contoured portion having a first end positioned toward the second endface and a second end positioned toward the first endface, wherein the contoured portion has a maximum height at or near the first end, and a minimum height at a position between the first end and the second end.

Abstract: Compounds that inhibit HIF-2?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2?.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange and/or surface heat exchange.

Abstract: Devices and methods for cooling all or part of the body of a human or animal subject by inserting a heat exchange catheter into the subject's body and infusing into or through the catheter a heat exchange medium that contains liquid phase matter and frozen solid phase matter, wherein at least some of the solid phase matter melts while in the catheter.

Abstract: A peristaltic pump has an arcuate raceway wife a partially concave inner surface extending through an arc of at least one hundred eighty degrees (180°). The are defines a midpoint, and a rotor faces the inner surface of the raceway and is both rotatable relative to the raceway and transitionally movable relative to the raceway between a pump position, wherein the rotor is spaced from the midpoint a first distance, and a tube load position, wherein the rotor is spaced from the midpoint a second distance greater than the first distance. A rotor motor is coupled to the rotor to rotate the rotor and rollers arranged on the rotor to contact tubing disposed between the rotor and the raceway when the rotor is in the pump position. A loading motor moves the rotor toward and away from the raceway.

Abstract: A peristaltic pump has an arcuate raceway with a partially concave inner surface extending through an arc of at least one hundred eighty degrees (180°). The arc defines a midpoint, and a rotor faces the inner surface of the raceway and is both rotatable relative to the raceway and translationally movable relative to the raceway between a pump position, wherein the rotor is spaced from the midpoint a first distance, and a tube load position, wherein the rotor is spaced from the midpoint a second distance greater than the first distance. A motor is coupled to the rotor to rotate the rotor plural are rollers arranged on the rotor to contact tubing disposed between the rotor and the raceway when the rotor is in the pump position. The motor is prevented from stopping at a predetermined angular position to facilitate loading and unloading tubing.

Abstract: Methods for treating a subject for a parasympathetic bias mediated condition are provided. Aspects of the methods include modulating at least a portion of the subject's autonomic nervous system to increase the sympathetic/parasympathetic activity ratio in a manner effective to treat the subject for the parasympathetic bias mediated condition. In some instances, the subject is known to have parasympathetic bias. Also provided are devices that find use in practicing various embodiments of the methods.