Abstract: An implant for left atrial appendage closure includes an expandable framework having a proximal end coupled to a collar, a shaft disposed within the collar and axially moveable relative to the collar, and a lock coupled to the shaft. The expandable framework is configured to expand from a collapsed delivery configuration to an expanded deployed configuration. The lock includes an engagement member configured to move between a constrained configuration and a radially expanded configuration, where the engagement member is biased in the radially expanded configuration.

Abstract: A medical system may include a left atrial appendage closure device including an expandable framework configured to shift between a collapsed delivery configuration and an expanded deployed configuration. The expandable framework has an outer diameter in the expanded deployed configuration. The medical system also includes a cinching member configured to shift between a compressed delivery configuration and an expanded configuration. The cinching member is ring shaped with an inner diameter in the expanded configuration that is larger than the outer diameter of the left atrial appendage closure device, and the cinching member has a plurality of tissue engagement elements defined on an outer surface thereof.

Abstract: The current disclosure describes techniques for managing vertical alignment or overlay in semiconductor manufacturing using machine learning. Alignments of interconnection features in a fan-out WLP process are evaluated and managed through the disclosed techniques. Big data and neural networks system are used to correlate the overlay error source factors with overlay metrology categories. The overlay error source factors include tool related overlay source factors, wafer or die related overlay source factors and processing context related overlay error source factors.

Abstract: A pacing system configured to sense cardiac activity and to deliver pacing therapy to a patient's heart. The pacing system may comprise a first electrode configured to be positioned in a first chamber of the heart and configured to deliver a first pacing therapy to the first chamber of the heart and a second electrode configured to be positioned in the left atrial appendage and configured to deliver a second pacing therapy to the left atrial appendage. The processing module of the pacing system may be configured to time a delivery of the first pacing therapy based on a first timing fiducial and a delivery of the second pacing therapy based on a determined pacing delay between the first pacing therapy and the second pacing therapy. The determined pacing delay may be configured to maximize a flow of blood into and/or out of the left atrial appendage.

Abstract: A medical device for causing blood flow within a left atrial appendage (LAA) includes a flow energy capture element adapted to capture energy caused by movement within the heart. A transmission element is operably coupled to the flow energy capture element, the transmission element adapted to utilize the captured energy to cause blood flow within the LAA.

Abstract: A left atrial appendage (LAA) ligation device is adapted for ligating the LAA via a trans-septal approach, the LAA including an ostium. The LAA ligation device includes a spiral ligation element extending from an end point disposed at a periphery of the spiral ligation element to a center point of the spiral ligation element, the spiral ligation element having a diameter defined by the periphery and a length defined between the periphery and the center point. A delivery device is adapted to releasably secure the spiral ligation element and to enable rotation of the spiral ligation device.

Abstract: An anthropomorphic test device includes a pelvis member. The pelvis member has a foam core and includes an abdomen region defining a first cavity and a pair of thigh regions extending from the abdomen region. The pelvis member also includes a buttock region positioned below the abdomen region and rearward of the pair of thigh regions. The buttock region defines a buttock cavity separate from the first cavity with the buttock region also defining at least one vent port. The buttock cavity compresses from an open condition to a collapsed condition when the anthropomorphic test device is placed onto a surface for approximating a force applied by a body weight of a human.

Abstract: The present invention relates to a brake controller for a towed vehicle braking system, including a housing or a loom, including an input connector for electrical connection to a towing vehicle and an output connector for electrical connection to a towed vehicle.

Abstract: A spine adjustment joint for use in a spine assembly of an anthropomorphic device with the device used to achieve a human-like response in crash test simulations. The joint includes a lower bracket which is coupled to a lower spine assembly and an upper bracket which is coupled to an upper spine assembly. The spine adjustment joint also includes a joint member at least partially formed of an elastomeric material that is coupled to each of the upper and lower bracket with the joint member providing flexibility between the upper and lower spine assembly. The spine assembly also includes at least one fastener passing through one of the upper and lower brackets and mounted to the joint member to secure the upper spine assembly in the desired angular position relative to the lower spine assembly.

Abstract: A left atrial appendage closure (LAAC) device includes an expandable member that defines a profile of the LAAC device and is moveable between a minimal diameter and a maximum diameter, the expandable member adapted to move to a deployment diameter that is intermediate the minimal diameter and the maximum diameter and that is limited by dimensions of a left atrial appendage (LAA) in which the LAAC device is deployed. A fabric extends over at least a portion of the expandable member and is adapted to accommodate changes in the expandable member between the minimal diameter and the increased diameter.

Abstract: Blood stagnation within a left atrial appendage (LAA) may be reduced by creating movement within the LAA. A variety of different actuatable devices, including magnetically actuated devices, may be implanted within the LAA. The actuatable device may be caused to become actuated, thereby causing the motion within the LAA. In some cases, causing the actuatable device to become actuated may include application of a magnetic field. In some cases, causing the actuatable device to become actuated may include subjecting the actuatable device to blood flow within the LAA.

Abstract: Blood stagnation within a left atrial appendage (LAA) may be reduced by creating movement within the LAA. A variety of different actuatable devices, including magnetically actuated devices, may be implanted within the LAA. The actuatable device may be caused to become actuated, thereby causing the motion within the LAA. In some cases, causing the actuatable device to become actuated may include application of a magnetic field. In some cases, causing the actuatable device to become actuated may include subjecting the actuatable device to blood flow within the LAA.

Abstract: The present invention relates to a brake controller for a towed vehicle braking system, including a housing or a loom, including an input connector for electrical connection to a towing vehicle and an output connector for electrical connection to a towed vehicle.

Abstract: Implanting a left atrial appendage closure (LAAC) device within a patient's left atrial appendage (LAA) may include advancing an assembly to a position proximate the patient's LAA. The assembly includes an LAAC device releasably secured to an LAAC delivery catheter, and one or more ultrasound transducers disposed relative to the LAAC delivery catheter. Once the LAAC device is deployed, the ultrasound transducers may be rotated relative to the LAAC device to look for leaks between the LAAC device and the LAA. In some cases, the LAAC device may be repositioned relative to the LAA when excessive leaks are found via ultrasound.

Abstract: An implantable medical device such as, but not limited to an LAAC (left atrial appendage closure) device includes an expandable frame that is moveable between a collapsed configuration for delivery and an expanded configuration for deployment, the expandable frame having a variable diameter in the expanded configuration. The expandable frame includes a central member, and a grouping of arcuate articulating members joined at one end to the first central member, each of the first grouping of arcuate articulating members extending outwardly from the first central member. A covering is disposed relative to the first grouping of arcuate articulating members.

Abstract: An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of articulating members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame. In some cases, the LAAC device may be adjustable to better fit a non-circular ostium.

Abstract: An implantable medical device includes an expandable frame that is expandable between a collapsed configuration for delivery and an expanded configuration for deployment, the expandable frame including a periphery defined by the expandable frame. A covering spans at least part of the expandable frame. An expandable element is secured relative to the periphery, the expandable element is adapted to seal against an irregular body opening such as an irregular-shaped ostium of a patient's LAA (left atrial appendage).

Abstract: An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of articulating members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame.

Abstract: A medical device system may include an occlusive implant including a central hub and a plurality of elongate members configured to shift between extended and radially expanded configurations. The central hub includes a plurality of conduits extending from a proximal end to a radially outward facing surface. The plurality of elongate members is configured to extend through the conduits in the radially expanded configuration. An implant remodeling tool may include an elongate sheath having at least one lumen, a plunger guide, and a plurality of plunger shafts extending from the at least one lumen through the plunger guide. The plunger guide is configured to direct the plunger shafts radially outward as the plunger shafts are advanced distally. The plunger shafts are configured to engage a medical implant and urge at least a portion of the implant radially outward.

Abstract: An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of frame members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame.