Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The steerable delivery system can contain a steerable rail configured for multi-plane bending to direct a distal end of the delivery system.

Abstract: A transtibial prosthetic socket frame may include a distal base assembly having a base plate, a carriage configured to support a socket suspension arrangement, and a distal prosthetic component connector. The distal base assembly supports a set of struts that includes two anterior struts and a single posterior strut. The set of struts and distal base assembly collectively define a prosthetic socket cavity having a central longitudinal axis and a residual limb hosting volume. The distal prosthetic component connector has a connecting adapter that is rotatable with respect to the prosthetic socket, and moveable with respect to the base plate between being aligned with the prosthetic socket's central longitudinal axis and a position offset therefrom.

Abstract: A photodetector has a photoactive layer of semiconducting inorganic nanoparticles positioned between a hole transport electron blocking layer of a first metal oxide and an electron transport hole blocking layer of a second metal oxide. The nanoparticles are responsive to electromagnetic radiation in at least the infrared region of the spectrum. The first metal oxide can be NiO, and the second metal oxide can be ZnO or TiO2. The metal oxide layers render the photodetector stable in air, even in the absence of an encapsulating coating around the photodetector. The photodetector has a P-I-N structure.

Abstract: A prosthetic socket for a residual limb of the lower extremity or upper extremity of an individual person is provided. The residual limb has particular dimensions and anatomical contours; the prosthetic socket has dimensions and contours that fit the dimensions and contours of the residual limb. The prosthetic socket may also fit in a manner that is biomechanically appropriate for the individual. The prosthetic socket may be an assembly from groups of components that include (a) struts arranged longitudinally with respect to the residual limb, (b) proximal brim members arranged proximally to the struts and connected thereto; and (c) distal socket members disposed at the distal base of the prosthetic socket. The socket components within these groups may be modular in that they can vary with respect to dimensions and/or contours, and yet have common connecting features that permit assembly of the components together to form the prosthetic socket.

Abstract: A system and method are described for profiling a distribution of forces transferred from the body weight and the residual limb of a wearer of a prosthetic socket through the socket. The system may include a prosthetic socket, a sensor network comprising multiple sensors coupled with the prosthetic socket in a pattern defining multiple internal regions within the prosthetic socket, and a processor coupled with the sensor network and configured to receive sensed data from the sensor network, divide the sensed data into groups corresponding to the multiple internal regions within the prosthetic socket, and process the sensed data to provide force distribution profile data corresponding to the force distribution profile.

Abstract: A prosthetic socket for a residual limb of the lower extremity or upper extremity of an individual person is provided. The residual limb has particular dimensions and anatomical contours; the prosthetic socket has dimensions and contours that fit the dimensions and contours of the residual limb. The prosthetic socket may also fit in a manner that is biomechanically appropriate for the individual. The prosthetic socket may be an assembly from groups of components that include (a) struts arranged longitudinally with respect to the residual limb, (b) proximal brim members arranged proximally to the struts and connected thereto; and (c) distal socket members disposed at the distal base of the prosthetic socket. The socket components within these groups may be modular in that they can vary with respect to dimensions and/or contours, and yet have common connecting features that permit assembly of the components together to form the prosthetic socket.

Abstract: A method and system converts OTC positions into contracts clearable at a futures clearing house. Each OTC position has a maturity date. The method comprises: a) defining a plurality of tenors. The plurality of tenors is fewer in number than the OTC maturity dates of the OTC positions. The method also comprises: b) defining a contract, which is clearable at the clearing house, corresponding to each tenor defined in step a); c) mapping each OTC position, as it is executed, into one or more of the contracts, based on the maturity date of the OTC position; and d) between business days, re-mapping each contract mapped at step c) to account for the move of calendar day. The invention finds particular application as a method and system to convert OTC Foreign Exchange (FX) positions into futures contracts clearable at a futures clearing house. The OTC FX positions may include OTC FX spot positions and OTC FX forwards positions.

Abstract: In some aspects, a consumable for plasma arc torch that generates a predetermined plenum pressure from a substantially constant preset gas supply pressure from a plasma arc torch power supply, where the substantially constant preset gas supply being used to support plasma generation for a selection of multiple consumable components that each generate a different plasma plenum pressure for carrying out different processes, can include a proximal portion shaped to connect to the plasma arc torch and define a plasma gas inlet region; a distal portion shaped to define a gas outlet; and a pressure-matching stage comprising a pressure wall defining at least one flow path between the gas inlet region and the gas outlet configured to establish sufficient fixed pressure drop of a flow of gas flowing through the pressure-matching stage to reduce a pressure of the flow of gas to the predetermined plenum pressure.

Abstract: An intra-frame positioning sling may be disposed internally within a prosthetic socket frame. The sling may include one or more proximal suspension portions adapted to suspend from a proximal aspect of the frame and a tensioning system. The sling may include a first longitudinal side with one or more proximal suspension portions and an opposite longitudinal side that includes the residual limb interfacing or force application portion of the sling. When the tensioning system is tensioned, the sling is pulled toward the first longitudinal side of the prosthetic socket frame. A set of two positioning slings may be rigged in a transfemoral prosthetic socket frame; one sling applies force on a medial side of a hosted residual limb, and the other sling applies force on the lateral side.

Abstract: A transtibial prosthetic socket frame may include a distal base assembly having a base plate, a carriage configured to support a socket suspension arrangement, and a distal prosthetic component connector. The distal base assembly supports a set of struts that includes two anterior struts and a single posterior strut. The set of struts and distal base assembly collectively define a prosthetic socket cavity having a central longitudinal axis and a residual limb hosting volume. The distal prosthetic component connector has a connecting adapter that is rotatable with respect to the prosthetic socket, and moveable with respect to the base plate between being aligned with the prosthetic socket's central longitudinal axis and a position offset therefrom.

Abstract: The invention relates to a prosthetic socket for a residual limb of the lower extremity or upper extremity of an individual person. The residual limb has particular dimensions and anatomical contours; the prosthetic socket has dimensions and contours that fit the dimensions and contours of the residual limb. The prosthetic socket may also fit in a manner that is biomechanically particularly appropriate for the individual. The prosthetic socket is an assembly of components from groups of components that include (a) struts arranged longitudinally with respect to the residual limb, (b) proximal brim members arranged proximally to the struts and connected thereto; and (c) distal socket members disposed at the distal base of the prosthetic socket. The socket components within these groups may be modular in that they can vary with respect to dimensions and/or contours, and yet have common connecting features that permit assembly of the components together to form the prosthetic socket.

Abstract: Embodiments of a modular prosthetic socket for a residual limb of a lower extremity of a patient are provided. Modular components include a base, multiple strut connectors, and multiple longitudinal struts. The base is selected from a collection of bases. The multiple strut connectors are selected from a collection of strut connectors, each strut connector being adjustably connectable to the base along the periphery of the base. The multiple longitudinal struts are selected from a collection of struts, each strut including a thermoplastic-fiber composite material, each strut being connectable to the base along the base periphery via one of the strut connectors. At least one of the component collections includes at least one of multiple sizes or multiple shapes of bases, struts or strut connectors, respectively. The prosthetic socket circumscribes a proximally-open internal space configured to conform to the residual limb of the patient.

Abstract: A system of multiple scoliosis treatment braces is custom fitted for a torso of a patient and organized in a sequential series, with each of the braces varying from a previous brace in the series by at least one shape characteristic. The sequential series of braces includes an initial treatment brace with an initial configuration that conforms to an initial shape of the torso, a final treatment brace with a final configuration that approximates a desired shape of the torso, and at least one intermediate treatment brace with an intermediate configuration that approximates a torso shape between the initial configuration and the final configuration. The initial configuration, the intermediate configuration and the final configuration may be determined, at least in part, by a single digital profile of the torso of the patient.

Abstract: An alignable coupling assembly embodiment for coupling distal and proximal prosthetic components includes a pair of parallel circular plates rotatably disposed in the circular receptacle of a support plate. The circular plates are configured such that they can be unpressed or a pressed. The unpressed condition allows rotation of the paired plates and the pressed condition prevents such rotation by way of a first friction lock. The paired circular plates further have a rectangular slot into which a longitudinal connector is slidably disposed, and which is subject to a second friction lock that prevents sliding when the connector is pulled distally. Rotational movement of the plates and sliding movement of the connector in the slot cooperate to allow its positioning at any point within an anterior-posterior/lateral medial grid centered on the longitudinal axis of the proximal prosthetic component. A distal pull on the longitudinal connector engages both first and second friction locks.

Abstract: An osseointegrated abutment support socket for a residual limb in which an osseointegrated abutment has been implanted is described. The osseointegrated abutment support socket may include a distal socket base assembly, multiple longitudinal struts and a percutaneous site protector. The distal socket base assembly may include a base plate, a collar extending proximally from the base plate and forming a receptacle for receiving a distal end of the osseointegrated abutment, and a strut support ring disposed around the collar. The struts are connected at their distal ends to the strut support ring and extend proximally upward. The percutaneous site protector contacts a distal surface of the residual limb near a percutaneous site where the distal end of the osseointegrated abutment exits the residual limb.

Abstract: The invention relates to a prosthetic socket for a residual limb of the lower extremity or upper extremity of an individual person. The residual limb has particular dimensions and anatomical contours; the prosthetic socket has dimensions and contours that fit the dimensions and contours of the residual limb. The prosthetic socket may also fit in a manner that is biomechanically particularly appropriate for the individual. The prosthetic socket is an assembly of components from groups of components that include (a) struts arranged longitudinally with respect to the residual limb, (b) proximal brim members arranged proximally to the struts and connected thereto; and (c) distal socket members disposed at the distal base of the prosthetic socket. The socket components within these groups may be modular in that they can vary with respect to dimensions and/or contours, and yet have common connecting features that permit assembly of the components together to form the prosthetic socket.

Abstract: A liner garment for a prosthetic socket configured to accommodate a residual limb of a patient may include a main body, a gel cup and at least one support material layer. The main body may include an elastic, fluid permeable material layer extending around a full circumference of the liner garment and having a closed distal end and an open proximal end for accepting the residual limb of the patient. The gel cup is fluid impermeable and is positioned on the inner surface of the main body at its distal end. The support material layer is located on a portion of the outer surface of the main body and is made of a material that is less elastic than the fluid permeable material layer of the main body.

Abstract: An alignable coupling assembly embodiment for coupling distal and proximal prosthetic components includes a pair of parallel circular plates rotatably disposed in the circular receptacle of a support plate. The circular plates are configured such that they can be unpressed or a pressed. The unpressed condition allows rotation of the paired plates and the pressed condition prevents such rotation by way of a first friction lock. The paired circular plates further have a rectangular slot into which a longitudinal connector is slidably disposed, and which is subject to a second friction lock that prevents sliding when the connector is pulled distally. Rotational movement of the plates and sliding movement of the connector in the slot cooperate to allow its positioning at any point within an anterior-posterior/lateral medial grid centered on the longitudinal axis of the proximal prosthetic component. A distal pull on the longitudinal connector engages both first and second friction locks.

Abstract: The invention relates to a prosthetic socket for a residual limb of the lower extremity or upper extremity of an individual person. The residual limb has particular dimensions and anatomical contours; the prosthetic socket has dimensions and contours that fit the dimensions and contours of the residual limb. The prosthetic socket may also fit in a manner that is biomechanically particularly appropriate for the individual. The prosthetic socket is an assembly of components from groups of components that include (a) struts arranged longitudinally with respect to the residual limb, (b) proximal brim members arranged proximally to the struts and connected thereto; and (c) distal socket members disposed at the distal base of the prosthetic socket. The socket components within these groups may be modular in that they can vary with respect to dimensions and/or contours, and yet have common connecting features that permit assembly of the components together to form the prosthetic socket.