Abstract: A secondary particle precursor, a positive electrode active material and a lithium secondary battery prepared from the same, and a method of preparing the same are disclosed herein. In some embodiments, a secondary particle precursor comprises one or more particles having a core and a shell surrounding the core, wherein a particle size (D50) of the secondary particle precursor is 6±2 ?m, a particle size (D50) of the core is 1 to 5 ?m, and the core has higher porosity than the shell. A positive electrode active material prepared using the secondary particle precursor has an increased press density and reduced cracking.

Abstract: A minimally invasive kit for diagnosing a skin condition comprises: a device capable of quantifying the expression level of an RNA gene from a specimen extracted from the skin of a subject; and a microneedle patch including a plurality of microneedles having a solid structure and made of a bioidegradable polymer hyaluronic acid. When the microneedle patch is applied to the skin of the subject and is detached after applied for a predetermined time, a specimen from the skin of the subject, which has been attached to the microneedle surfaces of the microneedle patch or an extract therefrom, is quantitatively analyzed by the device, and the device quantifies an expression level of each skin condition-related RNA biomarker gene to be diagnosed from the specimen from the skin of the subject, which has been attached to the microneedle surfaces of the microneedle patch or the extract therefrom.

Abstract: A multilayer electronic component includes a body including first and second surfaces opposing each other in a first direction, third and fourth surfaces connected to the first and second surfaces and opposing each other in a second direction, and fifth and sixth surfaces connected to the first to fourth surfaces and opposing each other in a third direction and including a dielectric layer and internal electrodes alternately disposed with the dielectric layer interposed therebetween in the first direction, and external electrodes disposed on the third and fourth surfaces, wherein the external electrodes include an electrode layer disposed on the body and a conductive resin layer disposed on the electrode layer, and the conductive resin layer includes a conductive metal, an epoxy resin, and an acrylic resin.

Abstract: A display apparatus includes a display; a communicator configured to communicate with a plurality of external apparatuses, which respectively provide a plurality of contents; and a processor. The processor is configured to: based on receiving information relating to contents among the plurality of contents from external apparatuses, respectively, through the communicator, identify the external apparatuses that transmitted the information, among the plurality of external apparatuses, control the display to display a UI including the contents respectively received from the identified external apparatuses, and control the display to display, on the UI, reproduction states of the contents to be visually distinguishable according to states of inputs of users of the received contents, the inputs being received through the identified external apparatuses, respectively.

Abstract: The present invention relates to human skin-derived fibroblasts having a tendon regeneration effect and a pharmaceutical composition for regenerating and treating a tendon, and the allogeneic skin-derived fibroblasts may have similar cell morphology to tenocytes, have a high expression level of vimentin, which is a fibroblast marker, express a large amount of extracellular matrix proteins, TGF-?, and increase collagen synthesis by acting on an ERK signaling mechanism, thereby effectively regenerating an injured tendon.

Abstract: A multilayer electronic component includes a body including first and second surfaces opposing each other in the first direction, and third and fourth surfaces connected to the first and second surfaces and opposing each other in a second direction, a first external electrode including a first base electrode layer including glass and Ni and disposed on the third surface, a first intermediate electrode layer including an alloy containing Sn and Ni and disposed on the first base electrode layer, and a first conductive resin layer including a resin and a metal and disposed on the first intermediate electrode layer and extending to the first and second surfaces, a second external electrode including a second base electrode layer disposed on the fourth surface, a second intermediate electrode layer disposed on the second base electrode layer, and a second conductive resin layer disposed on the second intermediate electrode layer.

Abstract: A display device includes a bank disposed on a substrate, the bank surrounding at least a portion of each of a first emission area and a second emission area in a plan view; first alignment electrodes, at least a number of the first alignment electrodes being disposed in the first emission area; second alignment electrodes, at least a number of the second alignment electrodes being disposed in the second emission area; and a light emitting element disposed in each of the first emission area and the second emission area. An electrode most adjacent to the second emission area among the first alignment electrodes and an electrode most adjacent to the first emission area among the second alignment electrodes are spaced apart from each other with a dividing line disposed therebetween, and the dividing line overlaps the bank in a plan view.

Abstract: A display device includes a substrate including a display area and a non-display area surrounding the display area, a plurality of sub-pixels including a first sub-pixel and a second sub-pixel, an upper bank layer surrounding the sub-pixels and the display area, a plurality of color control members including a first wavelength conversion layer in the first sub-pixel and a second wavelength conversion layer in the second sub-pixel, a plurality of color filter layers including a first color filter layer on the first wavelength conversion layer, and a second color filter layer on the second wavelength conversion layer, and a third color filter layer, a dam member surrounding the display area in the non-display area, and a valley between the dam member and the upper bank layer and surrounding the display area. The third color filter layer is on the first color filter layer in the non-display area.

Abstract: The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-CD19 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind CD19, as well as methods of making and using these anti-CD19 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: The present invention relates to a pyrrolobenzodiazepine dimer prodrug and a ligand-linker conjugate compound thereof, a composition containing these, and therapeutic use thereof particularly as an anticancer drug. The stability of the compounds themselves and the stability thereof in plasma are excellent and the compounds are advantageous in terms of manifestation of toxicity, and thus the compounds are industrially useful in that it is possible to target proliferative diseases such as cancer, to perform a specific treatment, to maximize the drug efficacy, and to minimize the occurrence of side effects.

Abstract: The present disclosure relates to a binder for coating a secondary battery separator including a (meth)acrylic copolymer containing a first structural unit derived from (meth)acrylonitrile; a second structural unit derived from (meth)acrylic acid or (meth)acrylate; and a third structural unit derived from (acet)amides, and a separator for a secondary battery and a secondary battery including the same.

Abstract: A display device includes a first substrate including a display area and a non-display area, an inorganic layer disposed on the first substrate in the non-display area, color filter pattern layers disposed on the inorganic layer and spaced apart from each other, a second substrate facing the first substrate, a light blocking member disposed on a surface of the second substrate and not overlapping the color filter pattern layers in the non-display area, and a seal member disposed between the first substrate and the second substrate and contacting the color filter pattern layers and the inorganic layer.

Abstract: Provided are a sacrificial positive electrode material with a reduced gas generation amount and a method of preparing the same. The sacrificial positive electrode material includes a lithium cobalt zinc oxide represented by Chemical Formula 1 (LixCo(1-y)ZnyO4) and the sacrificial positive electrode material has a powder electrical conductivity of 1×10?4 S/cm to 1×10?2 S/cm. The sacrificial positive electrode material can reduce the generation of gas, particularly, oxygen (O2) gas, during charging and discharging of a battery after activation and achieve a high charge/discharge capacity by including a lithium cobalt metal oxide represented by Chemical Formula 1 (LixCo(1-y)ZnyO4), which is doped with a specific fraction of zinc, and by having a powder electrical conductivity adjusted within a specific range, and thus the stability and lifespan of a battery including the same are effectively enhanced.

Abstract: Provided is a novel method for preparing a long-acting drug conjugate and a long-acting drug conjugate prepared using the method.

Abstract: A cathode active material for a lithium secondary battery according to an embodiment of the present invention includes a lithium metal oxide particle that contains tungsten and has a secondary shape in which a plurality of primary particles are aggregated. The lithium metal oxide particle includes a sulfur-containing portion formed between the primary particles in an inner region of the lithium metal oxide particle.

Abstract: A composition suitable for diagnosing a musculoskeletal disease and a composition suitable for preventing or treating a musculoskeletal disease are disclosed. The composition contains zinc finger protein with KRAB and SCAN domains 8 (Zkscan8) protein, which can be effectively used as an excellent biomarker for obtaining accurate information about the occurrence and progression stages of a musculoskeletal disease, specifically a tendon disease or a ligament disease. The compositions containing Zkscan8 can be effectively used for preventing or treating a musculoskeletal disease through Zkscan8 overexpression.

Abstract: Disclosed are novel compounds of Chemical Formula 1, optical isomers of the compounds, and pharmaceutically acceptable salts of the compounds or the optical isomers. The compounds, isomers, and salts exhibit excellent activity as GLP-1 receptor agonists. In particular, they, as GLP-1 receptor agonists, exhibit excellent glucose tolerance, thus having a great potential to be used as therapeutic agents for metabolic diseases. Moreover, they exhibit excellent pharmacological safety for cardiovascular systems.

Abstract: The present disclosure relates to a pharmaceutical composition for preventing or treating inflammatory bowel disease, comprising an intestinal organoid and a TNF? inhibitor. The combination use of the intestinal organoid and TNF? inhibitor according to the present disclosure can alleviate symptoms of inflammatory bowel disease such as weight loss, diarrhea, and bloody stool, and can inhibit fibrosis of the intestinal mucosa due to inflammation. In particular, when the intestinal organoid and the anti-inflammatory TNF? inhibitor are used in combination, the therapeutic effect is significantly superior to that of multiple administrations of the TNF? inhibitor, and thus it can be usefully used as an agent for preventing or treating inflammatory bowel disease.

Abstract: A display device prevents cracks from spreading to an active area. The display device includes a substrate including an active area and a non-active area having a bending area, a thin-film transistor disposed in the active area, a light-emitting element disposed in the active area and connected to the thin-film transistor, an encapsulation layer disposed on the light-emitting element, a touch sensor disposed on the encapsulation layer, a touch pad disposed in the non-active area, a first routing line connecting the touch sensor to the touch pad via a second routing line in the bending area, and a crack prevention layer disposed on the second routing line in the bending area. Thus, the crack prevention layer is capable of preventing the occurrence of cracks in the bending area BA, thus preventing cracks from spreading to the active area AA.

Abstract: The present disclosure relates to a facility guide robot that provides necessary information to a user who uses the facility while moving inside the facility. Specifically, the present disclosure relates to a facility guide robot and a facility guide method using the same, wherein the facility guide robot may actively provide the guide information to the facility users before the facility user requests to use the facility guide robot. That is, the convenience of the facility user may be improved by allowing the facility guide robot to provide the guide information necessary to the facility user before the facility user, who needs the guide, checks or calls the facility guide robot to receive the guide information.