Abstract: The present invention provides a novel compound having a protein kinase inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof. The compound according to the present invention, stereoisomers thereof or pharmaceutically acceptable salts thereof are effective in preventing or treating protein kinase-related diseases such as cancers, autoimmune diseases, neurological diseases, metabolic diseases, infections or the like by showing a protein kinase inhibitory activity.

Abstract: The present invention relates to a cosmetic composition for reducing wrinkles, improving moisturization, and improving skin barriers, the cosmetic composition comprising, as active ingredients, exosomes derived from Beluga caviar which are the eggs of the beluga sturgeon. The Beluga caviar exosomes provided by the present invention have excellent MMP-1 mRNA expression-inhibiting activity, COL1AL mRNA expression-increasing activity, FBN1 mRNA expression-increasing activity, HAS3 mRNA expression-increasing activity, and INV mRNA expression-increasing activity, and thus can be utilized as a cosmetic composition for reducing wrinkles, improving moisturization, and improving skin barriers.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: A bioreactor for suspension cells is provided. The bioreactor for suspension cells may comprise: a frame unit; a driving unit mounted on the frame unit, and a cell culture unit including a housing having an inner space filled with a medium containing suspension cells, and a plurality of supports disposed in multiple stages in the inner space to be spaced at intervals from each other, the cell culture unit having one end axially coupled to the driving unit.

Abstract: An embodiment vehicle truss member includes a member body having a pipe shape having an open end and an end patch coupled to the open end of the member body to close the open end of the member body, the end patch including a coupling part configured to be selectively coupled to an external element.

Abstract: A method of generating an image according to the present invention includes receiving a specific content selected from a user terminal among a plurality of contents provided from a content providing service, specifying a source image based on the selected specific content, generating a resulting image using the source image and a drawing style of the specific content, and providing the resulting image to the user terminal.

Abstract: Provided is a composition capable of promoting osteogenic differentiation of stem cells, comprising, as active ingredients, a bone and cartilage progenitor cell culture solution and a multilayer graphene film, which promotes the differentiation of stem cells into specific cells, and thus is expected to be variously applicable in the in vivo/in vitro stem cell application fields.

Abstract: A method of providing information on medical personnel may be provided. The method according to an embodiment may include: receiving surgical information including information on a medical treatment department performing a surgery, information on an operating surgeon, surgical category information, and surgical code information; determining a score for each item that constitutes the surgical information on medical personnel on the basis of information on on-duty records of the medical personnel; determining a medical personnel score corresponding to the surgical information on the basis of a weighted value corresponding to the score for the each item; and providing information on the medical personnel that includes the medical personnel score.

Abstract: The present invention relates to an alkyl acrylate compound-vinyl cyanide compound-aromatic vinyl compound graft copolymer including a seed prepared by polymerizing one or more compounds selected from the group consisting of an alkyl acrylate compound, an aromatic vinyl compound, and a vinyl cyanide compound and a multifunctional crosslinking agent; a core formed to surround the seed and prepared by polymerizing an alkyl acrylate compound and a multifunctional crosslinking agent; and a graft shell formed to surround the core and prepared by polymerizing an aromatic vinyl compound and a vinyl cyanide compound, wherein the multifunctional crosslinking agent has a weight average molecular weight of 600 to 1,400 g/mol, a method of preparing the alkyl acrylate compound-vinyl cyanide compound-aromatic vinyl compound graft copolymer, and a thermoplastic resin composition including the alkyl acrylate compound-vinyl cyanide compound-aromatic vinyl compound graft copolymer.

Abstract: Disclosed is a method for operating and participating in a voice chat room subordinate to a message chat room is disclosed. The method for operating a voice chat room subordinate to a message chat room includes: managing, by a server, messages transmitted and received through the message chat room in which a first user and a second user participate; receiving, by the server, a request for creation of the voice chat room subordinate to the message chat room from the first user; creating, by the server, the voice chat room in response to the received request for creation of the voice chat room; providing, by the server, information that the voice chat room is being operated to the second user through the message chat room; providing, by the server, information that the voice chat room is being operated to the second user through a message chat room list.

Abstract: A method of controlling a portable device including first and second touch screens is provided. The method includes displaying first information related to a first application on the first touch screen and displaying second information related to the first application on the second touch screen; receiving a first user input moving to the first touch screen on the second touch screen; and replacing the first information and the second information with a third information and a fourth information related to the first application on the first and second touch screens, in response to receiving the first user input, wherein each of the third information and the fourth information is displayed while being slidden from the second touch screen to the first touch screen and the third information is displayed over a boundary between the first and second screens during the sliding of the third and fourth information.

Abstract: Provided are an optical member and an optical display device comprising same, the optical member comprising a support layer and an optically functional layer laminated on one surface of the support layer, wherein: the optically functional layer includes a groove having inclined surfaces; at least one convex portion extending from the flat portion of the optically functional layer is formed at each of the inclined surfaces; the convex portion is a curved surface with a radius of curvature of 1 mm or greater, and each of the inclined surfaces satisfies expression 1.

Abstract: The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: wherein X, Z, R1 and R2 are as defined in the specification. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Abstract: A multilayer electronic component includes a body including a dielectric layer including Ba and Ti and an internal electrode disposed alternately with the dielectric layer; and an external electrode disposed on the body, wherein the dielectric layer further includes Li and F, and wherein a content of Li included in the dielectric layer is 0.02 mole or more and 0.36 mole or less based on 100 moles of Ba included in the dielectric layer.

Abstract: Disclosed are a polycyclic compound with a specific fused ring structure and an organic light emitting device including a light emitting layer that employs the polycyclic compound. The use of the polycyclic compound ensures significantly long lifetime and improved luminous efficiency of the device.

Abstract: A micro probe array device and method of manufacturing are disclosed. In the micro probe array device, a plurality of working electrodes are arranged in an array form, so that an individual electric signal can be applied to an object for each working electrode. In the micro probe array device, the height of the working electrode may be different, the working electrode and the counter electrode may constitute a double electrode, or the substrate may be made of a flexible material.

Abstract: A system on chip includes a processor and an input and output circuit including a plurality of input and output elements connected to the processor, wherein the plurality of input and output elements includes: a first input and output element spaced apart from the processor by a first distance; and a second input and output element spaced apart from the processor by a second distance, greater than the first distance, and connected to the processor by a first electrical path extending through a first region of the first input and output element, and wherein the first input and output element is connected to the processor by at least one first terminal provided in a second region that is separate from the first region.

Abstract: An image decoding is performed by steps including: determining whether or not to perform filtering on a boundary of a current block; determining a filtering strength on the boundary of the current block, and a number of samples used in filtering; and performing filtering on the boundary of the current block on the basis of the filtering strength and the number of samples used in filtering, where the number of samples used in filtering is determined on the basis of a size of the current block.

Abstract: Provided are a method and server for providing a content list. The method and server for providing a content list includes: providing source content to a chat room, receiving a request for providing a content list related to the source content from a first terminal of a first member; providing at least one of a first content list including at least one keyword-related content selected from among the entire contents stored in the server based on a keyword of the source content and a second content list including at least one group-related content belonging to the same group as a group of the source content among the entire contents, receiving information on selection content selected by the first member among the contents included in the at least one content list, from the first terminal, and providing the selection content to the chat room.

Abstract: The present invention relates to a pouch-type battery cell, a device for bending a pouch wing in the battery cell, and a method for bending a pouch wing in the battery cell, and specifically, relates to a pouch-type battery cell capable of improving insulation resistance performance of the battery cell by bending a pouch wing while heat-treating a sealing part of the pouch wing in the battery cell, thereby preventing and removing cracks in the sealing part, a device for bending a pouch wing in the battery cell, and a method for bending a pouch wing in the battery cell.