Abstract: Provided are an extracellular vesicle collecting apparatus using an electrode and a porous membrane and a method for using the same. The extracellular vesicle collecting apparatus includes i) an upper frame in which a pair of through holes is disposed so that a buffer solution flows therethrough, ii) a buffer tube which is inserted in the through holes and in which the buffer solution flows, iii) a positive electrode disposed on the upper frame, iv) a porous membrane located below the upper frame, v) a spacer which is located below the porous membrane and has a hollow space disposed therein, vi) a plurality of guide tubes through which a blood flows in the hollow space, vii) a lower frame which is coupled to the upper frame to be opposite to the upper frame and receives the porous membrane and the spacer therein, and viii) a negative electrode provided below the lower frame. Extracellular vesicles contained in the blood are collected by the porous membrane.

Abstract: Provided are a biocompatible pressure sensor which can be implanted into a body to wirelessly measure an internal pressure of the body outside the body, and a method of manufacturing the biocompatible pressure sensor. The biocompatible pressure sensor includes a coil inductor, a capacitor electrically connected with the coil inductor to constitute an LC resonant circuit together with the coil inductor, a flexible membrane disposed while being spaced apart from the coil inductor with an internal space interposed therebetween and surrounded by a housing, and a pressure displacement member fixed to one surface of the flexible membrane facing the coil inductor. The flexible membrane is transformed by external pressure to change a distance between the coil inductor and the pressure displacement member.

Abstract: A method for manufacturing a nerve electrode that is inserted into a living body and that is configured to attach to nerves is provided. The nerve electrode includes: i) a flexible substrate; ii) a plurality of electrodes that are separately positioned on the flexible substrate; and iii) an insulating layer that is positioned at a separation space of the plurality of electrodes and that insulates the plurality of electrodes. The plurality of electrodes include i) at least one linear electrode, and ii) a planar electrode that is separated from the linear electrode. An anti-inflammatory drug transfer layer is positioned on the planar electrode.

Abstract: A nerve electrode that is inserted into a living body and that is configured to attach to nerves is provided. The nerve electrode that is inserted into a living body and that is configured to attach to nerves includes: i) a flexible substrate; ii) a plurality of electrodes that are separately positioned on the flexible substrate; and iii) an insulating layer that is positioned at a separation space of the plurality of electrodes and that insulates the plurality of electrodes. The plurality of electrodes include i) at least one linear electrode, and ii) a planar electrode that is separated from the linear electrode. An anti-inflammatory drug transfer layer is positioned on the planar electrode.

Abstract: The present invention relates to an apparatus and a method for fabricating a microcapsule, more particularly to an apparatus and a method for fabricating a microcapsule, which enable to encapsulate uniform cell number in a microcapsule through cell distribution, improve cell viability in the microcapsule through fluid exchange, and ensure uniform microcapsule size. The apparatus for fabricating a microcapsule according to the present invention uses a plurality of microchannels which are spatially connected with one another and are designed such that fluid flows through them in a particular direction, and comprises a cell supply unit which supplies a fluid mixture of cells and a cell dropletizing material; and a droplet forming unit in which a dropletization inducing fluid supplied from one of the plurality of microchannels joins with the fluid mixture of the cells and the cell dropletizing material to form a droplet.

Abstract: A nerve electrode that is inserted into a living body and that is configured to attach to nerves is provided. The nerve electrode that is inserted into a living body and that is configured to attach to nerves includes: i) a flexible substrate; ii) a plurality of electrodes that are separately positioned on the flexible substrate; and iii) an insulating layer that is positioned at a separation space of the plurality of electrodes and that insulates the plurality of electrodes. The plurality of electrodes include i) at least one linear electrode, and ii) a planar electrode that is separated from the linear electrode. An anti-inflammatory drug transfer layer is positioned on the planar electrode.

Abstract: Disclosed are a system and a method for artificial nerve networking capable of restoring a damaged nerve and allowing selective detection, analysis, transmission and stimulation of a signal from the damaged nerve. The artificial nerve networking system according to an embodiment of the present disclosure includes: a first nerve conduit connected at one end of a damaged nerve; a second nerve conduit connected at the other end of the damaged nerve; and an artificial nerve networking unit electrically connected to the first nerve conduit and the second nerve conduit and recovering the function of the damaged nerve by transmitting and receiving a signal to and from the damaged nerve.

Abstract: Provided are an apparatus for detecting tumor cells including a tumor cell detection chip and a method for detecting tumor cells. The apparatus and method for detecting tumor cells according to the present disclosure enable convenient detection of tumor cells in short time and thus allow for treatment prior to metastasis of the tumor cells as well as easy diagnosis and clinical management of cancer patients. In addition, the detected tumor cells may be cultured as they are for use in genetic analysis.

Abstract: Provided are a DNA sequence analysis method of high precision providing improved optical limits by detecting wavelengths of lights emitted from labels in the state where a DNA is electrically tethered and completely stretch, and a nanodevice chip for automating the method. Also provided are a DNA sequence analysis method capable of removing binding errors through complementarily binding between a plurality of peptide nucleic acids (PNAs) labeled with labels emitting lights of different wavelengths and a target DNA to be sequenced, and resolving the limit in optical spatial resolution.

Abstract: Disclosed are a system and a method for artificial nerve networking capable of restoring a damaged nerve and allowing selective detection, analysis, transmission and stimulation of a signal from the damaged nerve. The artificial nerve networking system according to an embodiment of the present disclosure includes: a first nerve conduit connected at one end of a damaged nerve; a second nerve conduit connected at the other end of the damaged nerve; and an artificial nerve networking unit electrically connected to the first nerve conduit and the second nerve conduit and recovering the function of the damaged nerve by transmitting and receiving a signal to and from the damaged nerve.

Abstract: Disclosed is an apparatus and method for injecting liquid-drops of particle mixture liquid including a mixture of biological particles, affecting magnetic field, and having only positive particles, which are combined with magnetic responsive material, separated by magnetic force, and having negative particles, which are not combined with magnetic responsive material, precipitated by gravity.

Abstract: The present invention relates to an apparatus and a method for fabricating a microcapsule, more particularly to an apparatus and a method for fabricating a microcapsule, which enable to encapsulate uniform cell number in a microcapsule through cell distribution, improve cell viability in the microcapsule through fluid exchange, and ensure uniform microcapsule size. The apparatus for fabricating a microcapsule according to the present invention uses a plurality of microchannels which are spatially connected with one another and are designed such that fluid flows through them in a particular direction, and comprises a cell supply unit which supplies a fluid mixture of cells and a cell dropletizing material; and a droplet forming unit in which a dropletization inducing fluid supplied from one of the plurality of microchannels joins with the fluid mixture of the cells and the cell dropletizing material to form a droplet.

Abstract: Disclosed is an apparatus and method for injecting liquid-drops of particle mixture liquid including a mixture of biological particles, affecting magnetic field, and having only positive particles, which are combined with magnetic responsive material, separated by magnetic force, and having negative particles, which are not combined with magnetic responsive material, precipitated by gravity.

Abstract: A microchannel chip and a dilution method using the same capable of continuously diluting the diverse concentrations of solution by one time fluid injection using the microfluid technology are provided. The microchannels are formed in a plastic chip using the microfluid technology, and a width, a sectional area, or a length of the microchannel is regulated so that the flow rate of a diluted solution (e.g., buffer solution) and a sample (e.g., chemicals or medicament) is controlled. The diluted solution and the specimen are mixed in the mixing channel according to the flow rate, thereby diluting the sample. Such a diluted solution is mixed again with a diluted solution, carrying out the dilution. With the repeated dilution processes, continuously diluted solution is obtained.

Abstract: Disclosed relates to a method and an apparatus for measuring fluorescence polarization FP in a lab-on-a-chip and, more concretely, to a method and an apparatus that measure quantitatively interactions between biomolecules and fluorescently labeled biomaterials and enzyme activities using the measurement of fluorescence polarization FP. The method and the apparatus of the invention provide rapid assays with minute amounts of samples using an automated device compared to conventional methods. Accordingly, the method and the apparatus of the invention can be usefully applied to the measurement of interactions between biomolecules and to the protease assays using a protein substrate.

Abstract: A method for communication between inside and outside of a transmission medium using the transmission medium as a communication line, includes the steps of: receiving an electric signal having information related to a transmission medium from a plurality of sensors inside the transmission medium; conducting the electric signal to the transmission medium; and sensing the electric signal flowing to the outside of the transmission medium. Because a modulating unit is not necessary, a power consumption is minimized. In addition, since an electric signal is directly conducted to a medium, it is not necessary to use an antenna, and thus, degradation of a reception rate according to a directional property of the antenna can be prevented. Moreover, since the electric signal is directly generated in the medium and the medium is directly used as an electric conductor, the overall size of a transmitter is reduced.

Abstract: In a cantilever sensor and a fabrication thereof, by forming piezoelectric films on the same surface, it is possible to sense various information by an electric measuring method.

Abstract: A linear actuator capable of inducing a linear motion as well as a rotational motion using only two rotors is provided. The linear actuator includes: first and second rotors connected to respective driving force sources; a linear motion unit formed on the first rotor to be linearly movable; and a driving power transmission unit which is fixed to the second rotor and engages the linear motion unit. A linear motion on a rotor can be easily induced using a relative angular velocity difference between two rotors without an additional driving power source for the linear motion.

Abstract: In a cantilever sensor and a fabrication thereof, by forming piezoelectric films on the same surface, it is possible to sense various information by an electric measuring method.

Abstract: A method for communication between inside and outside of a transmission medium using the transmission medium as a communication line, includes the steps of: receiving an electric signal having information related to a transmission medium from a plurality of sensors inside the transmission medium; conducting the electric signal to the transmission medium; and sensing the electric signal flowing to the outside of the transmission medium. Because a modulating unit is not necessary, a power consumption is minimized. In addition, since an electric signal is directly conducted to a medium, it is not necessary to use an antenna, and thus, degradation of a reception rate according to a directional property of the antenna can be prevented. Moreover, since the electric signal is directly generated in the medium and the medium is directly used as an electric conductor, the overall size of a transmitter is reduced.