Abstract: The gas treatment apparatus includes: a column, an upper sealing head connected to an upper end of the column, and a lower sealing head connected to a lower end of the column, wherein: a fluid inlet pipe is arranged at a position of the column close to the upper scaling head, a fluid outlet end of the fluid inlet pipe extending into the column, and the fluid outlet end being connected to an absorption fluid spray nozzle used for spraying absorption fluid downwards; a gas inlet pipe is arranged at a position of the column close to the lower scaling head, and a gas outlet end of the gas inlet pipe extends into the column; the gas outlet end of the gas inlet pipe has connected thereto a microbubble-generating inner part; a back-mixing inner part is arranged in the column above the microbubble-generating inner part.

Abstract: Apparatuses, devices, and systems for controlling power supply to a load are described. A system can include a power stage and a power management integrated circuit (PMIC). The PMIC can include a controller configured to determine a load is operating under a low power mode. The controller can, in response to the load operating under the low power mode, operate the PMIC to supply power to the load. The controller can determine the load is operating under a high power mode. The controller can, in response to the load operating under the high power mode, operate at least one of the PMIC and the power stage to supply power to the load.

Abstract: Systems and methods for balancing a pair of battery cells are described. A controller can determine a voltage difference based on a first voltage of a first battery cell and a second voltage of a second battery cell. The controller can determine a current difference between current of an inductor and a current limit of the inductor, where the inductor can be connected to a node between the first and second battery cells. The controller can identify at least one switching elements among a plurality of switching elements based on the voltage difference and the current difference. The controller can activate the identified switching elements to perform battery cell balancing between the first battery cell and the second battery cell.

Abstract: Apparatuses, devices, and systems for controlling power supply to a load are described. A system can include a power stage and a power management integrated circuit (PMIC). The PMIC can include a controller configured to determine a load is operating under a low power mode. The controller can, in response to the load operating under the low power mode, operate the PMIC to supply power to the load. The controller can determine the load is operating under a high power mode. The controller can, in response to the load operating under the high power mode, operate at least one of the PMIC and the power stage to supply power to the load.

Abstract: The invention discloses a class of gold (I) Gefitinib derivatives, their preparation methods, and applications. The methods for preparing the gold (I) Gefitinib derivatives comprise the following steps: 1) Dissolve compound I and potassium hydroxide in methanol, and add a gold ligand II to obtain a mixture; 2) Stir the mixture for reaction, and then filter under reduced pressure to obtain a crude product; 3) Purify the crude product to obtain the gold (I) Gefitinib derivatives. One of the gold (I) Gefitinib derivatives has an EGFR/TrxR dual-target anti-lung cancer effect, retaining the stem nucleus structure of Gefitinib, 4-aniline-quinazoline, to ensure its original EGFR targeting inhibition activity, and introducing alkynyl groups with different carbon chain lengths to connect different gold ligands so that it can target both EGFR and TrxR simultaneously, enhancing its anti-lung cancer activity and overcoming the resistance of lung cancer to Gefitinib.

Abstract: The present disclosure relates to a method and apparatus for obtaining a clue in a virtual scene, a storage medium, and a program product. The method includes displaying a first virtual scene including multiple virtual characters and multiple virtual objects, where the multiple virtual characters include a first virtual character corresponding to a first user and a second virtual character corresponding to a second user, and controlling the first virtual character to interact with a first virtual object in response to a control instruction from the first user for the first virtual character to obtain a first search clue to be added to a clue pool.

Abstract: A dielectric material with heat transfer properties includes a first fluid and a second fluid different from the first fluid and miscible with the first fluid. The first fluid and the second fluid are mixed with each other so as to form a mixture and are kept at a temperature and a pressure so that the mixture is maintained in a supercritical phase. The mixture has at least one parameter that is preferably different from a corresponding parameter in both a supercritical phase of the first fluid and a supercritical phase of the second fluid. In a method of insulating electrical contacts and removing heat therefrom, the mixture is disposed about the electrical contacts and is maintained at a temperature and at a pressure that causes the mixture to be in a supercritical phase so that the mixture has favorable dielectric and heat transfer properties.

Abstract: Activity-inducible fusion proteins including a transcription factor and a heat-shock protein 90 (hsp90) binding domain are described. The activity of the transcription factor is regulated utilizing a drug molecule that binds the hsp90 binding domain. In the absence of the drug molecule, the transcription factor is in an inactive state but can be activated in the presence of the drug molecule. The activity-inducible transcription factors can be used to alter the activation state of immune cells, and optionally can be co-expressed with a chimeric antigen receptor (CAR).

Abstract: A dielectric material with heat transfer properties includes a first fluid and a second fluid different from the first fluid and miscible with the first fluid. The first fluid and the second fluid are mixed with each other so as to form a mixture and are kept at a temperature and a pressure so that the mixture is maintained in a supercritical phase. The mixture has at least one parameter that is preferably different from a corresponding parameter in both a supercritical phase of the first fluid and a supercritical phase of the second fluid. In a method of insulating electrical contacts and removing heat therefrom, the mixture is disposed about the electrical contacts and is maintained at a temperature and at a pressure that causes the mixture to be in a supercritical phase so that the mixture has favorable dielectric and heat transfer properties.

Abstract: A transaxle of a rail vehicle includes: a power assembly; an axle body; a running wheel; a guiding frame; a horizontal wheel; and a connecting rod component, including a first transverse pull rod and a second transverse pull rod, where when the rail vehicle turns left, the horizontal wheel cooperates with a rail beam to drive the guiding frame to swing and drive the first transverse pull rod to move together, and the second transverse pull rod is driven by the first transverse pull rod to drive the running wheel to swing to the left, and when the rail vehicle turns right, the horizontal wheel cooperates with the rail beam to drive the guiding frame to swing and drive the first transverse pull rod to move together, and the second transverse pull rod is driven by the first transverse pull rod to drive the running wheel to swing to the right.

Abstract: Aspects of the invention described herein relate to methods of making and using inducible promoters for transgene expression. The inducible promoters are derived from the NFAT-RE inducible system and are used to improve or enhance T cell survival and proliferation.

Abstract: Disclosed herein is a polynucleotide comprising a human codon-optimized sequence encoding a polypeptide comprising EGFR806CAR. The codon-optimized sequence may be incorporated into a construct comprising an optimal-functioning promoter, spacer, intracellular signaling domain, transmembrane domain, selection marker, at least one self-cleaving peptides, and EFGRt, in order to optimize expression. This sequence may then be expressed in cells, such as T cells, for the treatment or inhibition of a cancer, such as glioblastoma, liquid tumors, or solid tumors.

Abstract: Aspects of the invention described herein relate to methods of making and using inducible promoters for transgene expression. The inducible promoters are derived from the NFAT-RE inducible system and are used to improve or enhance T cell survival and proliferation.

Abstract: Some embodiments of the methods and compositions provided herein relate to systems comprising a promoter operably linked to a nucleic acid encoding a receptor, and an inducible promoter operably linked to a nucleic acid encoding a payload. In some embodiments, transcription from the inducible promoter is induced by activation of the receptor. In some embodiments, transcription from the inducible promoter is further modulated by inhibiting a signal between the activated receptor and the inducible promoter.

Abstract: A dead axle of a rail vehicle, a rail vehicle, and a rail transportation system are provided. The dead axle of a rail vehicle includes: an axle body; a running wheel; a guiding frame; a horizontal wheel; and a connecting rod component, including a first transverse pull rod and a second transverse pull rod, where when the rail vehicle turns left, the horizontal wheel cooperates with a rail beam to drive the guiding frame to swing and drive the first transverse pull rod to move together, and the second transverse pull rod is driven by the first transverse pull rod to drive the running wheel to swing to the left, and when the rail vehicle turns right, the horizontal wheel cooperates with the rail beam to drive the guiding frame to swing and drive the first transverse pull rod to move together, and the second transverse pull rod is driven by the first transverse pull rod to drive the running wheel to swing to the right.

Abstract: An information processing method is provided for a terminal device. The method includes obtaining an image including an AR target; recognizing the AR target, and generating a virtual scene including N virtual objects (N being an integer greater than or equal to 2); disassembling the virtual scene to obtain the N virtual objects; and generating object information that separately corresponds to the N virtual objects, which include a target virtual object to be interacted with by a user. The method also includes keeping the object information of virtual objects other than the target virtual object in the N virtual objects unchanged and updating the object information of the target virtual object in response to receiving an operation instruction inputted by the user for the target virtual object, such that the target virtual object is interacted independently rather than the virtual scene as whole by the user.

Abstract: Provided herein is a system for inducible expression of a chimeric antigen receptor in cells, such as mammalian cells.

Abstract: The present embodiments are directed to methods and apparatuses for operating a battery charger in computing systems having certain system load requirements, battery configurations and external device power supply support. According to some aspects, the present embodiments provide methods and apparatuses for providing a reverse boost mode of operation when the battery charger is providing system power from a battery, such as when an adapter is not connected. The reverse boost mode of operation according to embodiments provides a regulated output voltage, thereby allowing a load such as a CPU to operate at maximum performance, even when the battery has discharged below a threshold discharge level.

Abstract: Provided herein is a system for inducible expression of a chimeric antigen receptor in cells, such as mammalian cells.

Abstract: A microfluidic movement control method utilizing light, a device, and a microtubule actuator (2). The microtubule actuator (2) is prepared by utilizing a light-induced deformed smart polymer material. The smart polymer material forms, by an exciting beam, asymmetrical deformation, and is induced to produce a capillary action to drive a microfluid movement. The embodiment can drive microfluids having various polarities and compositions, and can drive creep of the microfluid, and can even drive the microfluid to generate a 3D movement trail. The embodiment has found a wide range of potential applications in controllable microfluidic transport, micro-reaction systems, micro-mechanic systems, IC laboratories, and others.