Abstract: This disclosure relates to bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and to methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such bivalent compounds.

Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue retraction device includes a first engagement member having a first end and a second end, a second engagement member having a first end and a second end, a first elastic member attached to the second end of the first engagement member, and a first alignment member having a first end, a second end and a lumen extending therethrough. Further, the tissue retraction device has a first length, the first alignment member has a second length, the first elastic member extends within the lumen of the first alignment member and the second length of the first alignment member is less than or equal to the first length of the tissue retraction device.

Abstract: Disclosed is a sediment core-drilling process for a submarine wire-line coring drill rig, including 1) lowering the drill rig; 2) drilling in a pressure-suction mode; 3) drilling in a rotation-pressure-suction mode; 4) cutting sediment cores; 5) recovering a core inner tube; 6) cleaning bottom of hole; 7) punching before adding a drill pipe; 8) lowering another core inner tube; 9) adding the drill pipe; 10) punching after adding the drill pipe; 11) repeating the steps 2)-10) until a given hole depth is reached; 12) recovering the drill pipe and a wire-line coring outer tube drilling tool; 13) recovering the submarine wire-line coring drill rig. The core-drilling process provided herein is suited to working conditions without mud lubrication and mud protection for hole wall. This invention has advantages of low disturbance and high efficiency in coring and is suitable for remote operation.

Abstract: Embodiments of the present disclosure relate to a method and apparatus for processing a video. The method can include: acquiring a to-be-processed video, and dividing the video into at least one video segment according to a scene; for a video segment of the at least one video segment, extracting a feature of the video segment; inputting the feature and a target video quality into a pre-trained encoding parameter prediction model, to obtain an encoding parameter of the video segment, the encoding parameter prediction model being used to represent a corresponding relationship between the feature of the video segment and the encoding parameter under the target video quality; and performing an encoding process on the video according to the encoding parameter corresponding to the video segment of the at least one video segment, to generate an encoded video.

Abstract: A method and device for secondary input of text are disclosed. The method may include: detecting a touch action, if the touch action meets a triggering requirement for a candidate split mode, activating the candidate split mode, and in the candidate split mode, selecting and splitting one of candidate results into an acceptable part and a pending part, wherein the acceptable part is presented in a target text field and a new candidate is acquired based on the character string corresponding to the pending part. With the present disclosure, users are allowed to modify a candidate result at any time as desired by retaining an accepted part of the candidate result during the input process, so as to simplify the input process. This entails a more prompt and more efficient input feedback mechanism which simplifies the user's manipulation and improves the user's experience.

Abstract: This invention relates to a method for inputting text by consecutive slide, comprising: detecting whether a consecutive slide input mode is triggered in response to an input of a user; detecting and recording a sliding trajectory of a user on a touch-screen and inputting a corresponding word; and predicting a possible word based on a context and another input of the user and updating the layout of a keyboard according to at least one of the results of the prediction. The invention also relates to a system that implements the method, as well as a corresponding device. The method, system and device increase input efficiency and achieve smart prediction and smart arrangement of candidate words in an area of the keyboard.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices that lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstructions for dissection tools. In particular, the present disclosure relates to devices that transition from a constrained to an unconstrained bowed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: A process for drilling natural gas hydrates. A drilling rig is placed in seawater. A suction-press core drilling mode is adopted in a soft sediment formation, a suction-rotary core drilling mode is adopted in a medium-hard sediment formation, or a pumping direction circle-rotary core drilling mode is adopted in a hard sediment formation. A core is extracted. An inner tube for wireline pressure coring is recovered. A holding seal cap is tightened, and the inner tube is stored in a pipe storage rack. Punching is carried out. An inner tube for wireline pressure coring which is hollow is captured to disengage the holding seal cap. The inner tube is lowered. A drill rod is added. The punching is carried out again. The above steps are repeated until the core drilling reaches a given drilling depth. The drill rod, the drill and the corer are recovered.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices that lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstructions for dissection tools. In particular, the present disclosure relates to devices that transition from a constrained to an unconstrained bowed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: Embodiments of the present disclosure relate to a method and apparatus for processing a video. The method can include: acquiring a to-be-processed video, and dividing the video into at least one video segment according to a scene; for a video segment of the at least one video segment, extracting a feature of the video segment; inputting the feature and a target video quality into a pre-trained encoding parameter prediction model, to obtain an encoding parameter of the video segment, the encoding parameter prediction model being used to represent a corresponding relationship between the feature of the video segment and the encoding parameter under the target video quality; and performing an encoding process on the video according to the encoding parameter corresponding to the video segment of the at least one video segment, to generate an encoded video.

Abstract: A melting pot includes a pot body and a float salvaging apparatus. The pot body is provided with a melting chamber having an open upper end. The float salvaging apparatus includes a hanging bracket, a bearing plate, a rotating plate and a drive assembly configured to drive pivoting of the rotating plate. The hanging bracket is disposed above the melting chamber. The rotating plate is pivotably disposed on the bearing plate, and the bearing plate and the rotating plate are provided on the hanging bracket between an initial position and a first salvaging position in a manner of moving up and down. The drive assembly is connected to the rotating plate.

Abstract: Disclosed is a sediment core-drilling process for a submarine wire-line coring drill rig, including 1) lowering the drill rig; 2) drilling in a pressure-suction mode; 3) drilling in a rotation-pressure-suction mode; 4) cutting sediment cores; 5) recovering a core inner tube; 6) cleaning bottom of hole; 7) punching before adding a drill pipe; 8) lowering another core inner tube; 9) adding the drill pipe; 10) punching after adding the drill pipe; 11) repeating the steps 2)-10) until a given hole depth is reached; 12) recovering the drill pipe and a wire-line coring outer tube drilling tool; 13) recovering the submarine wire-line coring drill rig. The core-drilling process provided herein is suited to working conditions without mud lubrication and mud protection for hole wall. This invention has advantages of low disturbance and high efficiency in coring and is suitable for remote operation.

Abstract: Disclosed is a process for drilling natural gas hydrates with a submersible core drilling rig using pressure wireline, including: 1) placing the drilling rig in seawater; 2) adopting a suction-press core drilling mode in a soft sediment formation, a suction-rotary core drilling mode in a medium-hard sediment formation, or a pumping direct circle-rotary core drilling mode in a hard sediment formation; 3) extracting a core; 4) recovering an inner tube for wireline pressure coring; 5) tightening a holding seal cap and storing the inner tube in a pipe storage rack; 6) punching; 7) capturing an inner tube for wireline pressure coring which is hollow and disengaging the holding seal cap; 8) lowering the inner tube; 9) adding a drill rod; 10) punching; 11) repeating steps (2˜10) till the core drilling reaches a given drilling depth; 12) recovering the drill rod and the drill; 13) recovering the corer.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: A method and device for secondary input of text are disclosed. The method may include: detecting a touch action, if the touch action meets a triggering requirement for a candidate split mode, activating the candidate split mode, and in the candidate split mode, selecting and splitting one of candidate results into an acceptable part and a pending part, wherein the acceptable part is presented in a target text field and a new candidate is acquired based on the character string corresponding to the pending part. With the present disclosure, users are allowed to modify a candidate result at any time as desired by retaining an accepted part of the candidate result during the input process, so as to simplify the input process. This entails a more prompt and more efficient input feedback mechanism which simplifies the user's manipulation and improves the user's experience.

Abstract: This disclosure relates to a method, device and user equipment for pushing service information. The method comprises: monitoring a status of a call; determining whether to trigger a push of the service information based on the status of the call; acquiring at least one piece of the service information and a corresponding pushing manner based on the status of the call; and pushing at least one piece of the service information to a current call status interface. The present disclosure enables accurate pushing of service information to a user by taking into account the progress of the call.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices that lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstructions for dissection tools. In particular, the present disclosure relates to devices that transition from a constrained to an unconstrained bowed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: A method and system for text input by a continuous sliding operation is provided.