Abstract: The present invention relates to the technical field of clustered regularly interspaced short palindromic repeats (CRISPR). In particular, the present invention relates to a Type I-A CRISPR-Cas effector protein and system, a fusion protein comprising the protein, and nucleic acid molecules encoding same. The present invention also relates to a complex and composition for nucleic acid editing (e.g., gene or genome editing, large fragment deletion, single base editing, genomic structural variation), which comprises the protein or fusion protein of the present invention, or nucleic acid molecules encoding same. The present invention further relates to a method for nucleic acid editing (e.g., gene or genome editing, large fragment deletion, single base editing, genomic structural variation), which uses the protein or fusion protein comprised in the present invention.

Abstract: A children's dining chair includes a base, handles, and a backrest. A left side, a right side, and a rear side of the base are provided with blocking walls. A first storage slot is defined in the blocking walls. The handles are detachably arranged on the left side and the right side of the base. The backrest is detachably arranged on the rear side of the base. When the handles and backrest are disassembled from the base, the handles and the backrest are capable of being stored in the first storage slot.

Abstract: This application relates to the field of power tool technologies, and specifically discloses a power tool and a control method thereof. The tool includes at least two output heads. An output head detection assembly can detect a position of an output head at a working position and generate a detection signal. The detection signal is associated with a working mode of the output head. A function switching unit generates, in response to external triggering, a mode switching signal used for indicating to switch the working mode of the output head at the working position. A controller is connected to the output head detection assembly and the function switching unit, switches the working mode of the output head at the working position in response to the mode switching signal, and associates the detection signal with a working mode after switching.

Abstract: A lockset includes symmetrically arranged front and rear handle assemblies, where the rear handle assembly includes a rear fixing base and a rear handle body. The rear fixing base is mounted on a door leaf. A connecting rod is configured to connect the front and rear assemblies. With a head facing rearward, a first fastening screw is provided outside the rear handle body to lock and connect the rear fixing base to the connecting rod. The rear handle body is provided with a through hole corresponding to the fastening screw. A movable cover body is configured to cover or expose the through hole for convenient operation. The rear handle body includes a supporting shaft and a housing. The housing and the cover body together form a gripping portion. The through hole is provided in the housing. An avoidance groove is provided on an outer side of the supporting shaft.

Abstract: This application discloses a battery tray and a battery formation and capacity-grading device. The battery tray includes a fixed frame; and a fixed component located in the fixed frame, the fixed component including a first limiting assembly and a second limiting assembly, the first limiting assembly including at least two first limiting members which extend along a first direction respectively and are spaced apart along a second direction which intersects the first direction, the second limiting assembly being connected to the first limiting assembly and including at least two second limiting members which are disposed along the first direction and are connected with the first limiting members to form a limiting space for accommodating a battery cell, and the second limiting members being movably disposed along the first limiting members in the first direction.

Abstract: The present invention relates to the field of nucleic acid editing, in particular to the field of clustered regularly interspaced short palindromic repeat (CRISPR) technology. Specifically, the present invention relates to Cas effector proteins, fusion proteins comprising such proteins, and nucleic acid molecules encoding them. The present invention also relates to complexes and compositions for nucleic acid editing (e.g., gene or genome editing), which comprise the proteins or fusion proteins of the present invention, or nucleic acid molecules encoding them. The present invention also relates to a method for nucleic acid editing (e.g., gene or genome editing), which uses the proteins or fusion proteins comprising the present invention.

Abstract: The application discloses a switching power supply with constant current output and a method for controlling constant current of a switching power supply, wherein the switching power supply comprises a detection circuit and a logic control chip, and the detection circuit is configured to output a feedback voltage. The feedback voltage is a sum voltage of a first voltage and a second voltage, and the second voltage represents output current of the switching power supply. The logic control chip is configured to receive the feedback voltage and compare the feedback voltage with a reference voltage. When the output current changes, the logic control chip changes turn on time of the switching power supply based on comparison result to control the output current constant.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods for reading text within digital images utilizing multimodal language models. In particular, in some embodiments, the disclosed systems generate, utilizing a first visual encoder, a first set of visual features of a digital image comprising text. In addition, in some embodiments, the disclosed systems generate, utilizing a second visual encoder, a second set of visual features of the digital image. Moreover, in some embodiments, the disclosed systems determine, utilizing a visual-text encoder, a text string corresponding to the text of the digital image. Furthermore, in some embodiments, the disclosed systems generate, for a query directed to the text of the digital image, a response from the first set of visual features, the second set of visual features, and the text string utilizing a large language model.

Abstract: The present invention provides a bath stand, which includes a base plate and a connecting base. The base plate includes a base plate main body and a base plate extension part; a base plate connection structure for connecting the base plate extension part to the base plate main body is arranged between the base plate extension part and the base plate main body. The connecting base is located above the base plate. A supporting assembly is arranged between the connecting base and the base plate to space the base plate apart from the connecting base vertically. A lower end of the supporting assembly is connected to the base plate; and an upper end of the supporting assembly is connected to the connecting base.

Abstract: A door lock with both manual and electric unlocking functions includes a lock body and a transmission rod. The lock body is provided with a latch for locking a door leaf. The transmission rod is in a transmission connection with the latch. When the transmission rod is manually or electrically driven to rotate forward or backward, the transmission rod is configured to drive the latch of the lock body to retract or extend, thereby achieving opening or closing of the door leaf. The door lock further includes a first housing, a rotating disc, and a rotating member. A misalignment device is arranged between the rotating disc and the rotating member. The misalignment device includes an idling area and a block, a controller, and a drive motor. The door lock further includes a positioning member fixedly arranged on the first housing.

Abstract: The present invention discloses an image enhancement system and an implementation method therefor. The system comprises a media signal processing apparatus, an image enhancement apparatus, a microscope body, and a binocular tube. The image enhancement apparatus comprises a housing, and a display device and a superposition lens group that are disposed in the housing, the display device is connected to the media signal processing apparatus, the superposition lens group is disposed on a main optical path of the microscope body, the binocular tube is disposed on the microscope body, the display device is configured to receive information data sent by the media signal processing apparatus and convert the received information data into an optical image, the optical image sent by the display device is superposed to the main optical path of the microscope body through the superposition lens group to form a superposed image, and the superposed image can be observed through the binocular tube.

Abstract: An electronic lock configured with internal and external modules includes a first module and a second module installed on inner and outer sides of a door leaf, respectively. The first module includes a first housing and a first circuit board accommodated in the first housing, and the second module includes a second housing and a second circuit board accommodated in the second housing. The first module further includes a first conductive contact arranged on the first circuit board and a first conductive post electrically signal-connected to the first conductive contact, and the second module further includes a second conductive contact arranged on the second circuit board and a second conductive post electrically signal-connected to the second conductive contact; and one of the first conductive post and the second conductive post is formed with an insertion cavity, and the other conductive post can be inserted into the insertion cavity.

Abstract: An optical structure and a display apparatus are provided. The optical structure includes a lens structure, a beam splitting film, a phase retardation film and a reflective polarizing film. The plurality of metal layers includes a mixed metal layer, a material of the mixed metal layer includes at least two metals, and the at least two metals include a first metal and a second metal. The non-metal layer that is in direct contact with the mixed metal layer and located on a side of the mixed metal layer close to the lens structure is a layer to be deposited, and an interfacial energy between the first metal and the layer to be deposited is less than an interfacial energy between the second metal and the layer to be deposited.

Abstract: A door lock with both manual and electric unlocking functions includes a lock body and a transmission rod. The lock body is provided with a latch for locking a door leaf. The transmission rod is in a transmission connection with the latch. When the transmission rod is manually or electrically driven to rotate forward or backward, the transmission rod is configured to drive the latch of the lock body to retract or extend, thereby achieving opening or closing of the door leaf. The door lock further includes a first housing, a rotating disc, and a rotating member. A misalignment device is arranged between the rotating disc and the rotating member. The misalignment device includes an idling area and a block, a controller, and a drive motor. The door lock further includes a positioning member fixedly arranged on the first housing.

Abstract: The present invention provides a method for forming a reversible membraneless organelle in microorganisms. In the present invention, in order to form a membraneless organelle in a host cell, an artificial short peptide sequence WGR-1 is fused on the basis of an intrinsically disordered protein RGG. Fusion of one WGR-1 sequence or two WGR-1 sequences connected in series can both effectively promote phase separation of RGG, thus forming a membraneless organelle in Saccharomyces cerevisiae, wherein the membraneless organelle RGG-(WGR-1)2 has a better liquid fluidity. RGG-x-(WGR-1)2 is further constructed by introducing an enzyme cleavage site x into the RGG-(WGR-1)2 system in the present invention, and the reversible formation of the membraneless organelle is achieved after expression of a protease is induced. The method of the present invention has important value in customizing and controlling cell functions and the like.

Abstract: The present invention provides a method for forming a reversible membraneless organelle in microorganisms. In the present invention, in order to form a membraneless organelle in a host cell, an artificial short peptide sequence WGR-1 is fused on the basis of an intrinsically disordered protein RGG. Fusion of one WGR-1 sequence or two WGR-1 sequences connected in series can both effectively promote phase separation of RGG, thus forming a membraneless organelle in Saccharomyces cerevisiae, wherein the membraneless organelle RGG-(WGR-1)2 has a better liquid fluidity. RGG-x-(WGR-1)2 is further constructed by introducing an enzyme cleavage site x into the RGG-(WGR-1)2 system in the present invention, and the reversible formation of the membraneless organelle is achieved after expression of a protease is induced. The method of the present invention has important value in customizing and controlling cell functions and the like.

Abstract: A folding bathtub includes a bathtub body and a supporting body. The supporting body is provided with a support frame and support legs, the support legs are connected with the support frame, and the support frame is supported by the support legs. The support frame is detachably connected with the bathtub body, and the bathtub body is supported by the support frame, so that the support frame can be connected with the bathtub body when the bathtub body needs to be used by a user, the bathtub body is supported by the support legs and the support frame, and the bathtub body is prevented from being deformed to be convenient for the user to use.