Patents by Inventor Jian Fan

Jian Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200339572
    Abstract: The present disclosure discloses a compound as represented by formula (I) or a pharmaceutically acceptable salt, a solvate or an isomer thereof, a pharmaceutical composition and a pharmaceutical preparation comprising the same, and the application thereof in the field of medicine. As a selective inhibitor of cyclin-dependent kinase 4/6 (CDK4/6), the compound of the present disclosure may be used for treating or preventing a disease at least partially modulated by CDK4/6, such as breast cancer and colon cancer.
    Type: Application
    Filed: April 13, 2020
    Publication date: October 29, 2020
    Applicant: Wuxi Shuangliang Biotechnology Co., Ltd.
    Inventors: Jiaquan Wu, Feng Fan, Shuai Zhang, Zhenghua Lu, Chengchen Wang, Jian Dong, Jie Zhang, Teng Wang, Xiaoyi Ji, Minqi Gao
  • Publication number: 20200342991
    Abstract: Presented are concepts for detecting recurrence of a medical condition in a subject previously treated for the medical condition. One such concept comprises, using natural language processing, extracting information from a data set comprising information relating to the subject prior to and/or during the subject's previous treatment for the medical condition. The extracted information is reformulated into structured data based on a standardized model. A data retrieval request comprising a structured query adhering to a template is obtained and, based on the structured query of the data retrieval request, data is retrieved from the structured data.
    Type: Application
    Filed: January 16, 2019
    Publication date: October 29, 2020
    Inventors: Yiyi Hu, Yan Li, Zuofeng Li, Huichuan Sun, Mao Hua Yang, Jian Zhou, Jia Fan
  • Publication number: 20200338874
    Abstract: A method of preparing an elastomer membrane with high water pressure resistance includes the following steps: preparing a dry material by subjecting first thermoplastic polyurethane (TPU) powder/particles to a drying treatment; preparing a first mixture by mixing the dry material thoroughly with one or a mixture of at least two of diethylenetriamine, diethylaminopropylamine, and diaminodiphenylmethane; preparing a second mixture by mixing an initiator thoroughly with the first mixture; preparing a first membrane layer from the second mixture; and preparing a second membrane layer and a third membrane layer through the above steps such that the second membrane layer and the third membrane layer are sequentially formed on the first membrane layer.
    Type: Application
    Filed: June 19, 2019
    Publication date: October 29, 2020
    Inventors: Shu-Hui HUANG, Sheng-Jen LIN, Yao-Hung KUO, Jian-Fan CHEN, Hung-Kung CHIEN, Yu-chuan LIN, Yun-chin KUO
  • Patent number: 10816535
    Abstract: The present invention relates to the field of material determination or analysis, and provides a method of assessing drying depth of cementitious materials including the following steps: preparing a plurality of cementitious material specimens; drying the cementitious material specimens; conducting electrochemical impedance spectrum measurement on each cementitious material specimen; accordingly determining a model for analyzing the drying depth of the cementitious material specimen. The method of assessing drying depth of the cementitious material provided by the present invention takes the influence of the resistivity changes on the model into consideration, and the drying depth of the cementitious material is reflected and reckoned with regularly changes of the electrochemical parameters, not only increasing the accuracy but also saving much testing labor, time and cost.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: October 27, 2020
    Assignee: SHENZHEN UNIVERSITY
    Inventors: Hongfang Sun, Feng Xing, Zhili Ren, Dawang Li, Jian Liu, Bing Fan
  • Publication number: 20200332079
    Abstract: A method of preparing a thermoplastic polyurethane membrane with high adhesion and high elasticity includes the following steps: (a) preparing a modifying solution, wherein the modifying solution is one or a mixture of at least two of diethylenetriamine, diethylaminopropylamine, and diaminodiphenylmethane; (b) preparing a semi-finished product by applying the modifying solution on at least one surface of a thermoplastic polyurethane membrane; and (c) subjecting the semi-finished product to a temperature of 50° C.˜180° C. in order for the semi-finished product to undergo a reaction and thus form the thermoplastic polyurethane membrane with high adhesion and high elasticity.
    Type: Application
    Filed: June 16, 2019
    Publication date: October 22, 2020
    Inventors: Shu-Hui HUANG, Sheng-Jen LIN, Yao-Hung KUO, Jian-Fan CHEN, Hung-Kung CHIEN, Yu-chuan LIN, Yun-chin KUO
  • Publication number: 20200302573
    Abstract: Disclosed are a display method, a display device, a virtual reality display device, a virtual reality device, and a storage medium. The display method includes: segmenting one frame of image into at least one image region; determining grayscale information of the image region; determining a resolution compression ratio of the image region according to the grayscale information of the image region, wherein a grayscale level of the image region is negatively correlated with the resolution compression ratio; and displaying an image in the image region according to the resolution compression ratio of each image region.
    Type: Application
    Filed: November 12, 2019
    Publication date: September 24, 2020
    Inventors: Bingxin Liu, Ziqiang Guo, Jian Sun, Feng Zi, Binhua Sun, Lin Lin, Yakun Wang, Jiyang Shao, Yadong Ding, Qingwen Fan
  • Patent number: 10776936
    Abstract: A method comprising: providing a first 3D point cloud and a second 3D point cloud about an object obtained using different sensing techniques; removing a scale difference between the 3D point clouds based on a mean distance of points in corresponding subsets of the first and second 3D point clouds; arranging the 3D point clouds in a two-level structure, wherein a first level is a macro structure describing boundaries of the object and a second level is a micro structure consisting of supervoxels of the 3D point cloud; constructing a first graph from the first 3D point cloud and a second graph from the second 3D point cloud such that the supervoxels represent nodes of the graphs and adjacencies of the supervoxels represents edges of the graphs; matching the first and second graph for obtaining a transformation matrix; and registering the 3D point clouds together by applying the transformation matrix.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: September 15, 2020
    Assignee: Nokia Technologies Oy
    Inventors: Lixin Fan, Xiaoshui Huang, Qiang Wu, Jian Zhang
  • Patent number: 10757211
    Abstract: A terminal receiving a push message is provided. The terminal sets service control condition which specifies application identifier (app ID) corresponding to service that the terminal is allowed to receive, wherein the service control condition is contained in push message control policy. And the terminal then receives a push message, matching the push message control policy, sent by a server.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: August 25, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Shunan Fan, Guoqiao Chen, Lei Wang, Ting Dong, Huiping Zhang, Jian Yang
  • Publication number: 20200235966
    Abstract: Apparatuses and methods related to digital mobile radio (DMR) with enhanced transceiver are disclosed herein. The transceiver detects waveforms of signals received by a digital mobile station radio (MS). By detecting whether the waveforms of the signals, the transceiver allows a digital baseband processor of the MS to remain in a sleep state while the signals are being detected by the DMR, thereby reducing an amount of power used while the signals are being detected.
    Type: Application
    Filed: February 6, 2019
    Publication date: July 23, 2020
    Applicant: Analog Devices International Unlimited Company
    Inventors: Jian WANG, Yong WANG, Haijiao FAN, Reza Alavi, Abdelaziz CHIHOUB, Esha JOHN, Saeed AGHTAR
  • Publication number: 20200211486
    Abstract: An array substrate, a display panel, a display device, and driving methods thereof are provided. The array substrate includes a plurality of subpixels arranged in an array, a plurality of data lines, and a plurality of switches. The plurality of subpixels include subpixels of a first color, subpixels of a second color, subpixels of a third color, and subpixels of a fourth color, in odd rows of subpixels, the subpixels of the first color, the subpixels of the second color, the subpixels of the third color, and the subpixels of the fourth color are sequentially arranged; in even rows of subpixels, the subpixels of the third color, the subpixels of the fourth color, the subpixels of the first color, and the subpixels of the second color are sequentially arranged; and each column of subpixels corresponds to and is connected with a data line.
    Type: Application
    Filed: August 22, 2019
    Publication date: July 2, 2020
    Inventors: Zhen WANG, Wenwen QIN, Mingchao MA, Wenchao HAN, Jian SUN, Yun QIAO, Jun FAN
  • Patent number: 10688670
    Abstract: A palm-type mechanical gripper with variable-position and rotatable fingers and a dual-drive crank-slider parallel mechanism is provided with a crank-slider mechanism on the left side, which is an active driving structure and is driven by two stepping motors to respectively generate angular displacement of cranks and to change lengths of connecting rods, and a crank-slider mechanism on the right side, which is a driven mechanism and is driven at a constant speed by a pair of gears. The mechanical gripper is provided with three plate spring fingers, wherein two fingers are respectively installed on the connecting rods on left and right sides, and under the cooperative effect of the two stepping motors, the eccentricities of the cranks, the positions and angles of the two fingers respectively on the two connecting rods and the position of the other fixed finger can be changed through manual adjustment.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: June 23, 2020
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Jun Zhang, Chenyang Fan, Jian Shen
  • Patent number: 10684241
    Abstract: A method for detecting clogging of a subsurface flow constructed wetland, including the steps of firstly emptying water in the subsurface flow constructed wetland, and then measuring the apparent resistivity of the subsurface flow constructed wetland bed after the water is emptied, wherein the water holding capacity of clogging sediments in the clogged region after emptying is strong, the apparent resistivity of this region is further measured to be lower than an unclogged region and the clogged region can thus be positioned and analyzed, the apparent resistivity of the region clogged more seriously is lower and the degree of clogging can thus be quantitatively analyzed.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: June 16, 2020
    Assignee: SHANDONG UNIVERSITY
    Inventors: Jian Zhang, Huaqing Liu, Zhen Hu, Chenglu Zhang, Jinlin Fan
  • Publication number: 20200157212
    Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to ROBO2, as well as uses, and methods thereof.
    Type: Application
    Filed: June 8, 2018
    Publication date: May 21, 2020
    Inventors: Stephen Berasi, Janet Elizabeth Buhlmann, Eric M. Bennett, Nathan Higginson-Scott, Huilan Gao, Zong Sean Juo, Stefano V. Gulla, Christine Huard, Sreekumar R. Kodangattil, Jian Li, Weining Lu, Xueping Fan, David J. Salant
  • Publication number: 20200157223
    Abstract: Provided is a bispecific recombinant protein, comprising a high affinity tumor-targeting arm and a low affinity fusion protein blocking the interaction of CD47 with SIRP?. The antibody corresponding to the high affinity tumor-targeting arm does not bind to CD47, and its binding affinity to the target antigen on the tumor cell is at least 6 times as great as the binding affinity of monomer fusion protein homodimer corresponding to the low affinity fusion protein blocking the interaction of CD47 with SIRP?, to a CD47 on the tumor cell, wherein the low affinity fusion protein blocking the interaction of CD47 with SIRP? comprises a SIRP? extracellular truncation. Also provided are nucleic acid molecules encoding recombinant proteins and the use of the recombinant proteins and nucleic acid molecules in the manufacture of a medicament for treating tumors.
    Type: Application
    Filed: May 8, 2018
    Publication date: May 21, 2020
    Applicant: SHANGHAI JMT-BIO TECHNOLOGY CO., LTD
    Inventors: Liping SONG, Xiaotian CUI, Jian WANG, Haixiang WU, Jiana JIA, Yi FAN, Ganliang ZHANG, Tao LI, Hong XU, Yisha SHE, Kai LONG
  • Publication number: 20200156944
    Abstract: The present invention is generally directed to improved processes for the preparation of various phosphorus oxides and phosphoric acid. Phosphorus oxides prepared in accordance with the present invention include phosphorus (III) oxides (e.g., tetraphosphorus hexaoxide (P4O6)). Phosphorus (III) oxides such as P4O6 are useful products and are also useful as precursors in preparation of other products, including phosphorous acid (H3PO3) and other phosphorus-containing chemicals. Certain aspects of this invention are also directed to using various byproducts formed during P4O6 production as precursors for the formation of phosphoric acid (H3PO4) and P2O5. In particular, the present invention is directed to improved processes for the preparation of phosphorus (III) oxides (e.g., P4O6) suitable for use in the preparation of phospho-herbicides such N-(phosphonomethyl)glycine (glyphosate) and precursors thereof (e.g., N-(phosphonomethyl)iminodiacetic acid (PMIDA)).
    Type: Application
    Filed: November 19, 2019
    Publication date: May 21, 2020
    Applicant: Monsanto Technology LLC
    Inventors: Eduardo Aurelio Casanova, Peng Fan, Justin Robert Struble, Jian Xu
  • Publication number: 20200130282
    Abstract: Examples disclosed herein relate to synchronize a thermal image and a 3D print process. In one implementation, a processor synchronizes a thermal image with a step in a 3D printing process based on an occluded region detected in the thermal image. The processor may output thermal information associated with the 3D print process step.
    Type: Application
    Filed: April 3, 2018
    Publication date: April 30, 2020
    Inventors: Jian Fan, Andrew E Fitzhugh, Jerry Jin-Tzong Liu
  • Publication number: 20200125830
    Abstract: A method of recognizing an object includes comparing a three-dimensional point cloud of the object to a three-dimensional candidate from a dataset to determine a first confidence score, and comparing color metrics of a two-dimensional image of the object to a two-dimensional candidate from the dataset to determine a second confidence score. The point cloud includes a color appearance calibrated from a white balance image, and the color appearance of the object is compared with the three-dimensional candidate. The first or second confidence score is selected to determine which of the three-dimensional candidate or the two-dimensional candidate corresponds with the object.
    Type: Application
    Filed: April 27, 2017
    Publication date: April 23, 2020
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Yang Lei, Jian Fan, Jerry Liu
  • Publication number: 20200125776
    Abstract: Disclosed are a collision check data processing method and apparatus, an electronic device, and a storage medium. The method comprises: acquiring generated collision check data, and acquiring an ID number of a collision part according to the collision check data; then acquiring ID numbers corresponding to selected designated parts from a preset database; and determining a target part under collision according to the ID numbers corresponding to the designated parts and the ID number of the collision part. According to the disclosure, a target part under collision can be determined among large amounts of collision check data according to an ID number corresponding to a designated part and an ID number of a collision part. That is, according to the disclosure, a single item among the collision check data can be checked according to a user requirement, thereby improving the check efficiency effectively.
    Type: Application
    Filed: June 22, 2018
    Publication date: April 23, 2020
    Inventors: Dongming WANG, Lin FAN, Kuigang GUO, Xiaoxia YAN, Jian XIONG, Jiazhi LI
  • Patent number: 10619108
    Abstract: The present disclosure relates to a method for a simulated moving bed to adsorb and separate polycyclic aromatic hydrocarbons. Zeolite, metal oxide and metal-modified materials are employed as adsorbent. Firstly, diesel oil flows through pre-treatment adsorbent to remove the trace amount of impurities. Secondly, the purified diesel oil flows through the simulated moving bed so that the PAHs can be separated from diesel oil. In this process, the valves are switched periodically, leading to the relative movement of adsorption beds. At the same time, desorbent is pumped into the equipment to wash out PAHs, achieving the continuous adsorption-regeneration operation. Thirdly, simple distillation is employed to separate desorbent from clean diesel oil and PAHs, respectively. Finally, the fractions of clean diesel oil and PAHs can be obtained, respectively. The separated desorbent can be recycled. The PAHs removal rate can reach to 90%.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: April 14, 2020
    Assignees: CNOOC TIANJIN CHEMICAL RESEARCH & DESIGN INSTITUTE CO. LTD., CHINA NATIONAL OFFSHORE OIL CORP., CNOOC ENERGY TECHNOLOGY & SERVICES LIMITED
    Inventors: Haibin Yu, Jiazhong Zang, Bin Li, Jingxin Fan, Chang Shu, Zhiyu Sui, Xunzhi Zhao, Yueqiu Pan, Yan Liu, Hong Cheng, Jian Li
  • Patent number: 10617690
    Abstract: The present invention discloses a series of JAK inhibitors, and particularly discloses a compound of formula (I) or a pharmaceutically acceptable salt thereof and the use thereof in preparation of drugs for treating diseases related to JAK.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: April 14, 2020
    Assignee: WUXI FORTUNE PHARMACEUTICAL CO., LTD
    Inventors: Hao Wu, Weiwei Mao, Lili Fan, Charles Z. Ding, Shuhui Chen, Fei Wang, Guoping Hu, Jian Li