Abstract: A universal alternating current (AC) inverter system with galvanic isolation takes an unregulated direct current (DC) input and provides a high-quality AC output that may be used in conjunction with both linear and non-linear loads. The universal AC inverter system includes a DC-DC converter for converting an unregulated DC input to a regulated DC output, and a DC-AC inverter for converting the regulated DC output to a high-quality AC output. The DC-DC converter includes a DC link isolation high frequency transformer that provides galvanic isolation between the unregulated DC input and the AC output. To avoid saturation of the transformer, the controller for the DC-DC converter employs a DC offset correction loop that prevents accumulation of DC content on the primary side of the transformer. The universal AC inverter system includes a 4-phase inverter topology that converts the regulated DC voltage provided by the DC-DC converter to an AC output.

Abstract: A novel serine protein kinase, SRPK1, having a molecular weight of about 92 kD and phosphorylating the SR family of splicing factors in a cell-cycle regulated manner is described. Polynucleotide and polypeptide sequences for SRPK1 are provided as well as methods for modulating splicing and alternative splicing of precursor mRNAs.