Abstract: There is provided a method of culturing cells, the method comprising: obtaining a substrate assembly, the substrate assembly comprising: (i) a plurality of fibres, wherein each fibre has an internal channel running along its length; (ii) a first support at a first end of the plurality of fibres; (iii) a second support at a second end of the plurality of fibres; wherein at least one of the first support and the second support allows fluid communication across the support into the internal channels while preventing fluid communication across the support to the external surfaces of the plurality of fibres; introducing a first type of cells into the internal channels of the plurality of fibres; introducing a second type of cells onto the external surfaces of the plurality of fibres; and culturing cells on the substrate assembly in a bioreactor. Also provided is a substrate assembly for culturing cells.

Abstract: Provided are a new vertical cavity surface emitting laser structure and a manufacturing method thereof. The structure includes a substrate layer, a lower N-type DBR, an active region, an upper N-type DBR and a mixed dielectric DBR sequentially arranged from bottom to top, where a second-class tunnel junction is arranged on one side of the active region close to the upper N-type DBR, where the second-class tunnel junction is embedded in a bottom of the upper N-type DBR and surrounded by the upper N-type DBR, and the substrate layer, the lower N-type DBR, the active region, the upper N-type DBR, the mixed dielectric DBR and the second-class tunnel junction are all coaxial elliptical cylinders; negative electrodes are arranged on the lower N-type DBR, and positive electrodes are arranged on the upper N-type DBRs substrate layer.

Abstract: Provided herein are cytokine muteins and cytokine prodrugs and methods of making and using thereof.

Abstract: Automated systems and methods are provided for processing speech, comprising obtaining a trained machine learning model that has been trained using a cumulative historical data structure corresponding to at least one digitally-encoded speech representation for a plurality of telecommunications interactions conducted by a plurality of agent-side participants, which includes a first data corresponding to a score variable and a second data corresponding to a plurality of driver variables; applying the trained machine learning model: to a subset of data in the cumulative historical data structure that corresponds to a first agent-side participant of the plurality of agent-side participants, to generate a performance classification score and/or a performance direction classification score, to identify an intervention-target agent-side participant from among the plurality of agent-side participants, and to the cumulative historical data structure to identify an intervention training plan; and conducting at least on

Abstract: The disclosed embodiments relate to a content-recommendation method and apparatus, an electronic device, and a system. The method comprises: searching, by a recommendation system according to a determined tag, a content database for content matching the tag; and recommending, by the recommendation system, the matching content to a user corresponding to the tag. Content in the content database is determined according to first-type content acquired by an internal-operation system by means of matching and second-type content acquired by an external-operation system by means of matching.

Abstract: A power detector device includes a voltage generator circuit, a reference circuit, a level hold circuit and a comparator circuit. The voltage generator circuit generates a bias voltage and a detection voltage according to a power supply voltage. The reference circuit generates a first reference voltage according to the power supply voltage. The level hold circuit selectively transmits the first reference voltage to a node according to the bias voltage, outputs a second reference voltage via the node, and holds a level of the second reference voltage after stopping transmitting the first reference voltage to the node. The comparator circuit compares the second reference voltage with the detection voltage to generate a power detection signal.

Abstract: The present invention is related to a water-based binder composition and its application in water-based printing ink. The binder composition comprises a waterborne poly(meth)acrylate emulsion and a polyurethane. Such composition provides excellent alcohol tolerance, bond strength and resolubility.

Abstract: The disclosed technology generally relates to quartz crystal devices and more particularly to quartz crystal devices configured to vibrate in torsional mode. The quartz crystal device includes a fork-shaped quartz crystal comprising a pair of elongate tines laterally extending from a base region in a horizontal lengthwise direction of the fork-shaped quartz crystal. Each of the tines comprises a line structure vertically protruding out of a central portion of each of top and bottom surfaces thereof and elongated in the horizontal lengthwise direction. The line structures comprise sidewalls, and at least some of the sidewalls and adjoining ones of the top and bottom surfaces of the tines are adjoined by faceted corners. The quartz crystal device also includes first and second electrodes formed on each of the tines, where the first and second electrodes are formed on opposing ones of the sidewalls of each of the line structures.

Abstract: Disclosed are an operation control method of a headset, an operation control device of a headset, a ring headset, and a computer-readable storage medium. The method is applied to applied to a ring headset, and includes: in response to detecting that a user is wearing the ring headset, determining a wearing position where the user wears the ring headset; in response to determining that the wearing position is a user's finger, controlling the ring headset to operate a first working mode; or in response to determining that the wearing position is a user's ear, controlling the ring headset to operate a second working mode.

Abstract: A voltage detection method includes: outputting a corresponding one of voltages to be an input voltage according to a clock signal, a first detection signal, a reset signal and multiple first bits; generating the reset signal according to the clock signal and multiple currents, wherein the voltages and the currents are generated based on a power supply voltage; comparing the input voltage with a reference voltage to generate a second detection signal, and generating the first detection signal according to the second detection signal and an enable signal; and adjusting the first bits by a digital circuit according to the second detection signal during a trimming phase to determine the first bits, and outputting the first bits by the digital circuit and resetting the digital circuit according to the first detection signal during a voltage detection phase.

Abstract: The present invention is directed to compositions having chair-side handling properties comprising polymers for dental, soft tissue and combination products applications.

Abstract: A method for forming a high electron mobility transistor includes the steps of providing a substrate, forming a first epitaxial layer on the substrate, forming a plurality of first recesses in an upper portion of the first epitaxial layer, forming a second epitaxial layer on the first epitaxial layer and partially filling the first recesses to seal a plurality of first air slits in the first recesses, forming a third epitaxial layer on the second epitaxial layer, and forming a gate on the third epitaxial layer.

Abstract: A high electron mobility transistor includes a substrate having a continuous planar front surface, a first epitaxial layer directly and continuous disposed on the continuous planar front surface of the substrate, a plurality of first recesses arranged in an upper portion of the first epitaxial layer, a second epitaxial layer directly disposed on the first epitaxial layer and partially filling the first recesses and surrounding a plurality of first air slits in the first recesses, a third epitaxial layer disposed on the second epitaxial layer, and a gate disposed on the third epitaxial layer.

Abstract: The disclosed technology generally relates to quartz crystal devices and more particularly to quartz crystal devices configured to vibrate in torsional mode. In one aspect, a quartz crystal device configured for temperature sensing comprises a fork-shaped quartz crystal comprising a pair of elongate tines laterally extending from a base region in a horizontal lengthwise direction of the fork-shaped quartz crystal, wherein each of the tines has formed on one or both of opposing sides thereof a pair of vertically recessed groove structures laterally elongated in the horizontal lengthwise direction, wherein the pair of groove structures are separated in a horizontal widthwise direction by a line structure.

Abstract: The present disclosure provides a semiconductor device, the semiconductor device including a substrate, a nucleation layer, a buffer layer, an active layer and a gate electrode. The nucleation layer is disposed on the substrate, and the buffer layer is disposed on the nucleation layer, wherein the buffer layer includes a first superlattice layer having at least two heteromaterials alternately arranged in a horizontal direction, and a second superlattice layer having at least two heteromaterials vertically stacked along a vertical direction. The at least two heteromaterials stack at least once within the second superlattice layer. The active layer is disposed on the buffer layer, and the gate electrode is disposed on the active layer.

Abstract: The present disclosure provides a semiconductor device and a fabricating method thereof, the semiconductor device including a substrate, a nucleation layer, a buffer layer, an active layer and a gate electrode. The nucleation layer is disposed on the substrate, and the buffer layer is disposed on the nucleation layer, wherein the buffer layer includes a first superlattice layer having at least two heteromaterials alternately arranged in a horizontal direction, and a second superlattice layer having at least two heteromaterials vertically stacked along a vertical direction. The at least two heteromaterials stack at least once within the second superlattice layer. The active layer is disposed on the buffer layer, and the gate electrode is disposed on the active layer.

Abstract: The present disclosure relates to fusion molecules and chimeric molecules which comprise two components: an Ang-2 antagonist peptide linked to a VEGF-binding moiety. Further disclosed are methods of using said chimeric molecules to treat a patient cancer, proliferative retinopathy, neovascular glaucoma, macular edema, wet age-related macular degeneration (wAMD), macular edema following retinal vein occlusion (RVO), diabetic macular edema (DME), or diabetic retinopathy (DR).

Abstract: The disclosed technology generally relates to quartz crystal devices and more particularly to quartz crystal devices configured to vibrate in torsional mode. In one aspect, a quartz crystal device configured for temperature sensing comprises a fork-shaped quartz crystal comprising a pair of elongate tines laterally extending from a base region in a horizontal lengthwise direction of the fork-shaped quartz crystal. Each of the tines has formed on one or both of opposing sides thereof a vertically protruding line structure laterally elongated in the horizontal lengthwise direction. The quartz crystal device further comprises a first electrode and a second electrode formed on the one or both of the opposing sides of each of the tines and configured such that, when an electrical bias is applied between the first and second electrodes, the fork-shaped quartz crystal vibrates in a torsional mode in which each of the tines twists about a respective axis extending in the horizontal lengthwise direction.

Abstract: Disclosed are an electronic device including a shell, a rotating frame, a guide limit mechanism, a sensor and a controller. The rotating frame is rotatably provided outside a part of the shell and configured to rotate to at least two gears relative to the shell. In response to that the rotating frame rotates to any one of the gears, the rotating frame is snap-fitted with the shell for positioning through a gear limit mechanism; and in response to that the rotating frame is rotated out of the gears by an external force, the rotating frame is released from the shell. The guide limit mechanism is configured to limit a rotation range of the rotating frame. The sensor is configured to sense a current rotation gear of the rotating frame and connected to the controller which is configured to control and perform a corresponding function according to the current rotation gear.