Abstract: A process for sensor placement and analysis using a virtual environment includes receiving into a computer processor a model of an area, a position in the model that represents a placement of a virtual sensor, and an orientation of the virtual sensor. A shadow map of the area is generated as a function of the position and orientation of the virtual sensor. The shadow map is used to determine one or more portions of the area that can be sensed by the virtual sensor. The area of the model that is covered as a function of the position and orientation of the virtual sensor is determined, and information relating to the area of the model that is covered as a function of the position and orientation of the virtual sensor is transmitted to an output device.

Abstract: A process for sensor placement and analysis using a virtual environment includes receiving into a computer processor a model of an area, a position in the model that represents a placement of a virtual sensor, and an orientation of the virtual sensor. A shadow map of the area is generated as a function of the position and orientation of the virtual sensor. The shadow map is used to determine one or more portions of the area that can be sensed by the virtual sensor. The area of the model that is covered as a function of the position and orientation of the virtual sensor is determined, and information relating to the area of the model that is covered as a function of the position and orientation of the virtual sensor is transmitted to an output device.

Abstract: Three dimensional (3D) operational user interface generation systems and methods are described herein. For example, one or more embodiments include calculating a number of locations for a virtual camera, placing the virtual camera at each of the number of locations, generating a 3D image at each of the number of locations, implementing object information for each pixel of the 3D image, and generating a 3D user interface utilizing the 3D image at each of the number of locations.

Abstract: A major risk factor for ischemic heart disease is advanced age. In adult bone marrow and other tissues, the number and function of stem cells decline with aging. Telomerase reverse transcriptase (TERT) is a nuclear protein that decreases senescence. Myocardin (MYOCD) is a transcription factor for myogenesis. Thus a method is provided for the simultaneous delivery of the telomerase reverse transcriptase (TERT) and myocardin MYOCD genes that resuscitates mesenchymal stromal cells (MSCs) from aged adipose and bone marrow tissues by increasing their capacity for survival, proliferation, and differentiation. TERT+/MYOCD+ MSCs restores a capacity for repairing ischemic tissues via improved blood flow and revascularization.

Abstract: A system for guidance and navigation in a building. For example, the system may determine a route for egress or rescue of one or more people from a building with a hazardous condition. The system may process the route into waypoints and segments developed within a set of constraint rules. Semantic information about the building may be associated with the waypoints and/or segments. The waypoints and segments may be processed into navigation commands. The navigation commands may be formed in natural language from sentence templates. The system may additionally have 3D beacon audio to assist in guidance and navigation of the one or more people in the building.

Abstract: A process includes mapping a data format in an object in a source schema to a data format in an object in a destination schema. The process includes defining an attribute mapping, defining a relation between the data format in the object in the source and the data format in the object in the destination, mapping the data format in the object in the source to the data format in the object in the destination, and converting the data format in the object in the source to another data format within the source. When the object in the source has no analog in destination, a foreign object is introduced into the destination, and when the object in the destination refers to one or more dependent objects, one or more instances of referred objects are generated according to a predefined policy in the mapping.

Abstract: A method for realizing an automatic protection switching of a transmission device is provided, and the method includes that: according to a received automatic protection switching trigger condition and information of each line sub-card, which are transmitted by a cross sub-card via a Time Division Multiplexing Fabric to Framer Interface (TFI5) frame, a control sub-card determines to execute protection switching, and sends a protection switching command to the cross sub-card; and the cross sub-card completes the protection switching action. A system for realizing an automatic protection switching of a transmission device is also provided. According to the technical solution of the present invention, the automatic protection switching of the transmission device in an Optical Transport Network (OTN) is achieved conveniently.

Abstract: A process for sensor placement and analysis using a virtual environment includes receiving into a computer processor a model of an area, a position in the model that represents a placement of a virtual sensor, and an orientation of the virtual sensor. A shadow map of the area is generated as a function of the position and orientation of the virtual sensor. The shadow map is used to determine one or more portions of the area that can be sensed by the virtual sensor. The area of the model that is covered as a function of the position and orientation of the virtual sensor is determined, and information relating to the area of the model that is covered as a function of the position and orientation of the virtual sensor is transmitted to an output device.

Abstract: A process includes mapping a data format in an object in a source schema to a data format in an object in a destination schema. The mapping includes a set of options as a function of analogs in the source and destination schema. The process also includes defining an attribute mapping, defining a relation between the data format in the object in the source schema and the data format in the object in the destination schema, mapping the data format in the object in the source schema to the data format in the object in the destination schema, and converting the data format in the object in the source schema to another data format within the source schema. When the object in the source schema has no analog in destination schema, a foreign object is introduced into the destination schema, and when the object in the destination schema refers to one or more dependent objects, one or more instances of referred objects are generated according to a predefined policy in the mapping.

Abstract: A system for guidance and navigation in a building. For example, the system may determine a route for egress or rescue of one or more people from a building with a hazardous condition. The system may process the route into waypoints and segments developed within a set of constraint rules. Semantic information about the building may be associated with the waypoints and/or segments. The waypoints and segments may be processed into navigation commands. The navigation commands may be formed in natural language from sentence templates. The system may additionally have 3D beacon audio to assist in guidance and navigation of the one or more people in the building.

Abstract: Compositions and methods for regulating in vitro cell growth are disclosed, and for providing undifferentiated stem cells or embryonic cells that are suitable for transplantation into damaged tissues or organs, or for use in tissue repair. A representative method includes causing the overexpression or underexpression of GalT binding protein (GtBP), also referred to as GalT associated protein (GTAP), in a cell such that ubiquitination of at least one cellular protein associated with cell adhesion and/or cell-to-cell interaction is correspondingly increased or decreased, causing inhibition of cell growth when GTAP is overexpressed and causing enhanced cell growth when GTAP is underexpressed by the cell. As a result, growth of the cell is altered or regulated.

Abstract: Methods and compositions are disclosed for inhibiting, deterring or preventing apoptosis of cardiac myocytes, transplanted stem cells, vascular stem cells, and vascular smooth muscle cells by means of expressing or synthesizing clusterin. Also disclosed are methods and compositions for producing recombinant clusterin, or its biologically active peptides, and for induction of clusterin-associated lipoproteins or enzymes for deterring or preventing inflammatory injury and apoptosis induced by oxLDL, oxysterols, cytokines, and Fas Ligand. Also disclosed is an induction method and composition for enhancing expression of ALDH and ALDH-associated enzymes or co-factors to prevent cytotoxicity or detoxification. Therapeutic methods providing new expression or overexpression of clusterin in vascular or cardiac tissue are expected to inhibit the formation of atherosclerotic lesions, stabilize existing atherosclerotic plaques, and repair failing or damaged cardiac tissue.

Abstract: Methods and compositions are disclosed for inhibiting, deterring or preventing apoptosis of cardiac myocytes, transplanted stem cells, vascular stem cells, and vascular smooth muscle cells by means of expressing or synthesizing clusterin. Also disclosed are methods and compositions for producing recombinant clusterin, or its biologically active peptides, and for induction of clusterin-associated lipoproteins or enzymes for deterring or preventing inflammatory injury and apoptosis induced by oxLDL, oxysterols, cytokines, and Fas Ligand. Also disclosed is an induction method and composition for enhancing expression of ALDH and ALDH-associated enzymes or co-factors to prevent cytotoxicity or detoxification. Therapeutic methods providing new expression or overexpression of clusterin in vascular or cardiac tissue are expected to inhibit the formation of atherosclerotic lesions, stabilize existing atherosclerotic plaques, and repair failing or damaged cardiac tissue.

Abstract: Compositions and methods for regulating in vitro cell growth are disclosed, and for providing undifferentiated stem cells or embryonic cells that are suitable for transplantation into damaged tissues or organs, or for use in tissue repair. A representative method includes causing the overexpression or underexpression of GalT binding protein (GtBP), also referred to as GalT associated protein (GTAP), in a cell such that ubiquitination of at least one cellular protein associated with cell adhesion and/or cell-to-cell interaction is correspondingly increased or decreased, causing inhibition of cell growth when GTAP is overexpressed and causing enhanced cell growth when GTAP is underexpressed by the cell. As a result, growth of the cell is altered or regulated.

Abstract: An in vitro method of producing stem cells with potential to develop into cardiovascular myocytes is disclosed which comprises culturing myogenic stem cells obtained from the stromal or mesenchymal compartment of adult adipose tissue in a medium that favors myogenic development of the cells. These myogenic stem cells highly express telomerase and myocardin. A composition comprising fat-derived myogenic stem cells and/or differentiated cardiovascular myocytes and a method for treating a mammalian subject suffering from a cardiovascular disorder are also disclosed.

Abstract: A method of enhancing survival and differentiation of stem cells, and cells of myogenic lineage derived from said stem cells, when the cells are exposed to an inflammatory or apoptotic stimulus comprises culturing stem cells in vitro in a medium containing a statin, to produce statin-pretreated cells with enhanced resistance to inflammatory or apoptotic stimuli. Additionally, the statin-pretreated cells may be caused or allowed to differentiate into statin-pretreated cells of myogenic lineage (e.g., cells having a vascular or cardiac myocyte phenotype). The resulting inflammation- and apoptosis resistant cells may then be used for cell therapy, as in treating an ischemic or infarcted vessel or heart.

Abstract: Methods and compositions are disclosed for inhibiting, deterring or preventing apoptosis of cardiac myocytes, transplanted stem cells, vascular stem cells, and vascular smooth muscle cells by means of expressing or synthesizing clusterin. Also disclosed are methods and compositions for producing recombinant clusterin, or its biologically active peptides, and for induction of clusterin-associated lipoproteins or enzymes for deterring or preventing inflammatory injury and apoptosis induced by oxLDL, oxysterols, cytokines, and Fas Ligand. Also disclosed is an induction method and composition for enhancing expression of ALDH and ALDH-associated enzymes or co-factors to prevent cytotoxicity or detoxification. Therapeutic methods providing new expression or overexpression of clusterin in vascular or cardiac tissue are expected to inhibit the formation of atherosclerotic lesions, stabilize existing atherosclerotic plaques, and repair failing or damaged cardiac tissue.