Abstract: The present invention provides small-molecule inhibitors of BMP signaling and compositions and methods for inhibiting BMP signaling. These compounds and compositions may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds and compositions may also be used to treat subjects with Sjögren's syndrome, or diffuse intrinsic pontine glioma (DIPG).

Abstract: Methods, systems and apparatus for wireless communication are described. One example method of wireless communication includes receiving, by a wireless device from a network device, a first message comprising one or more parameters related to an error correction coding, and transmitting, by the wireless device to the network device, a data transmission using the error correction coding according to the one or more parameters.

Abstract: A blanking machine and a method for blanking a bar or pipe material are provided. The blanking machine includes a blanking assembly and a plurality of driving members. The blanking assembly includes a housing, a plurality of pairs of slide rails, and a plurality of striking blocks. The housing defines a plurality of radially distributed grooves. The pairs of slide rails are respectively installed in the grooves. The striking blocks are respectively slidably installed on the pairs of slide rails. The driving members are configured to respectively drive the striking blocks to reciprocate along the slide rails to strike a material to be processed.

Abstract: Embodiments of this disclosure may include a receiver with a reconfigurable processing path for different signal conditions. Such a receiver may reconfigure between a mixer-first configuration and an amplifier-first configuration. In the mixer-first configuration, an RF input signal is not passed through an LNA for amplification before processing the RF input signal for downconversion to baseband and eventual extraction of the information in the signal. In the amplifier-first configuration, an RF input signal is passed through an LNA for amplification before processing the RF input signal for downconversion to baseband and eventual extraction of the information in the signal. Reconfiguring the receiver between mixer-first and amplifier-first configurations may be performed based on detection of jammer signals and/or measurement of signal-to-noise ratio (SNR).

Abstract: A wireless communication method for use in a wireless terminal is disclosed.

Abstract: Wireless signal processing may be improved by using a configurable baseband filter (BBF) in the receive path of a transceiver. A configurable BBF may accommodate processing of different wireless signals in a single integrated circuit (IC) chip. For example, a single IC may support processing of 5G mmWave RF signals and 5G sub-7 GHz RF signals by reconfiguring the BBF with settings appropriate for the different wireless signals. The reconfiguring of the BBF may include adjusting a bandwidth of the BBF and/or adjusting a filter order of the BBF. The reconfiguring of the BBF may be performed in response to detection of jammer signals to improve rejection of the jammer signals.

Abstract: A wireless communication method for use in a wireless terminal is disclosed. The method comprises receiving, from a wireless network node, predefined control information associated with at least one first kind of search space set in a plurality of search space sets for a scheduled cell, determining at least one physical downlink control channel, PDCCH, candidate corresponding to at least one of the plurality of search space sets based on the predefined control information for the scheduled cell, and monitoring the at least one PDCCH candidate in a scheduling cell, wherein the plurality of search space sets comprises at least one second kind of search space set.

Abstract: Provided herein are methods of treating and/or managing cancer, which comprise administering to a patient Compound A, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof. Additionally, provided herein are methods of treating and/or managing cancer, which comprise administering to a patient Compound A, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof, in combination with a second agent selected from the group consisting of an anti-CD20 antibody, an HDAC inhibitor, a proteasome inhibitor, an anti-CD38 antibody, an anti-SLAMF7 antibody, a nuclear export inhibitor, a BCL-2 inhibitor, and an immune checkpoint inhibitor. Also provided herein are combination therapies for treating and/or managing cancer, which further comprise dexamethasone as a third agent.

Abstract: The present invention provides small-molecule inhibitors of BMP signaling and compositions and methods for inhibiting BMP signaling. These compounds and compositions may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds and compositions may also be used to treat subjects with Sjögren's syndrome, or diffuse intrinsic pontine glioma (DIPG).

Abstract: The present invention relates to the preparation of a novel tetradentate platinum (II) complex and an application thereof, belonging to the field of OLED organic electroluminescent materials. The complex of the present invention has the following structural formula, and is used for a phosphorescent doping material having a photon emission effect in a light-emitting layer of an OLED luminescent device. The complex of the present invention has a high fluorescence quantum efficiency, a good heat stability and a low quenching constant, and can be used for the manufacture of a green light OLED device with a high luminous efficiency and low roll-off.

Abstract: Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which can be used for treating, for example, certain diseases. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as head and neck squamous cell carcinoma (HNSCC), cancer, blood disorders, etc.). Additional embodiments provide synergistic combinations of a BCL2 inhibitor with an IRAK inhibiting compound, and methods of using same.

Abstract: The present invention relates to the preparation and application of an O?C?N?N tetradentate platinum (II) complex. The complex of the present invention has a structure as shown in Formula (I) below. Compared with a reference device, the organic light-emitting device prepared by the present invention has better performance improvement, and the novel O?C?N?N tetradentate platinum (II) complex has great application value. The tetradentate platinum (II) complex involved in the present invention is based on a carbazole framework, and has a large ?-conjugated rigid planar structure, which can greatly reduce non-radiative energy dissipation such as intramolecular rotation and vibration, and is conducive to improving the luminous efficiency and performance of the platinum (II) complex.

Abstract: Embodiments of the present disclosure provide a diffusion muffling device, a diffusion resonance muffling device, a full-frequency diffusion muffling device, a muffling system for a ventilation channel, and a muffling method using the same, which include a plurality of diffusion muffling units disposed in the ventilation extension direction of the ventilation channel, wherein the plurality of diffusion muffling units are arranged in parallel in a direction with a predetermined angle between the direction and the ventilation extension direction of the ventilation channel, and a muffling passage is formed between each two adjacent diffusion muffling units, wherein each of the diffusion muffling units includes at least one diffuser, and each diffuser includes a plurality of convex portions so that sound waves entering the muffling passage are reflected multiple times in the muffling passage by the plurality of convex portions and then sound is attenuated.

Abstract: Described is a curable composition comprising a silane modified polymer; an epoxy resin terminated with epoxy terminal group; a compatibilizer having at least one silane group and at least one epoxy terminal group or at least one nitrogen-containing groups; and optionally a hardening agent; wherein the composition further optionally comprises at least one of a nitrogen-containing unsaturated heterocyclic compound catalyst and a nitrogen-containing phenol catalyst. The curable composition exhibits high hermeticity, fast curing speed, quick adhesion build up, dry surface and strong adhesion strength. A method for applying the curable composition on the surface of a substrate is also provided.

Abstract: This document generally relates to transmitting a feedback message from a first node to a second node, where the message indicates both a detection result of receiving at least a portion of a transport block, and addition information that indicates to the second node how to set one or more parameters for a subsequent transmission. In various embodiments, the message includes a value, such as an M-bit binary value that indicates both the detection result and the additional information.

Abstract: The present application relates to methods, systems, and devices related to digital wireless communication, and more specifically, to techniques related to a control channel monitoring procedure. In one exemplary aspect, a method for wireless communication is disclosed. The method includes detecting, by a terminal, an occurrence of an event. The method also includes selecting, by the terminal, a monitoring configuration based on the occurrence of the event. The method also includes resetting or stopping, by the terminal, any of a first timer and/or a second timer based on the occurrence of the event. The method also includes monitoring, by the terminal, a control channel according to the selected monitoring configuration.

Abstract: Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which can be used for treating, for example, certain diseases. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as head and neck squamous cell carcinoma (HNSCC), cancer, blood disorders, etc.). Additional embodiments provide synergistic combinations of a BCL2 inhibitor with an IRAK inhibiting compound, and methods of using same.

Abstract: The present disclosure discloses use of combined inhibition of LncRNA SAMMSON and BRAF kinase for delaying adaptive drug-resistance of melanoma. The present disclosure reveals that the RAF/MEK/ERK kinase can rapidly up-regulate the RNA level of LncRNA SAMMSON in BRAF-mutated melanoma cells. Knocking down the SAMMSON can significantly facilitate the BRAF kinase inhibitor vemurafenib-induced apoptosis and increase the sensitivity of the cells to vemurafenib.

Abstract: The present application relates to methods, systems, and devices related to digital wireless communication, and more specifically, to techniques related to channel coding and modulation. In one exemplary aspect, a method for wireless communication is disclosed. The method includes performing multiple operations that include a first operation related to pre-channel coding and/or a second operation comprising attaching redundancy check bits in an order. The method can also include generating a transmission waveform by a first node using one or more bits for transmission to a second node over a wireless channel using information derived from the multiple operations.

Abstract: A shared storage dynamic user quota system includes a storage management device coupled to a storage system having a shared storage space. The storage management device receives a data storage request from a user device to store data in the shared storage space. If the storage management device determines that the storage of the data in the shared storage space will exceed a user storage quota for a user associated with the user device, it determines whether the user qualifies to store the data in the shared storage space and exceed the user storage quota. In response to determining that the user qualifies to store the data in the shared storage space and exceed the user storage quota, the storage management device stored the data in the shared storage space.