Abstract: An antibody may be capable of specifically binding CD137 or an antigen binding fragment thereof, wherein the light chain variable region and the heavy chain variable region have one or more mutations. The antibody or antigen binding fragment thereof may be used in preparing a drug. The antibody or an antigen binding fragment thereof may specifically bind CD137, and may include a light chain variable region VL and a heavy chain variable region VH, wherein compared to a sequence as shown in SEQ ID NO: 103, the VL comprises one or more VL amino acid mutations, and the VL amino acid mutation occurs at one or more positions: V3, A10, K44, D71, and/or V77.

Abstract: The present application relates to methods, systems, and devices related to digital wireless communication, and more specifically, to techniques related to a control channel monitoring procedure. In one exemplary aspect, a method for wireless communication is disclosed. The method includes detecting, by a terminal, an occurrence of an event. The method also includes selecting, by the terminal, a monitoring configuration based on the occurrence of the event. The method also includes resetting or stopping, by the terminal, any of a first timer and/or a second timer based on the occurrence of the event. The method also includes monitoring, by the terminal, a control channel according to the selected monitoring configuration.

Abstract: Glasses containing silicon dioxide (SiO2) and/or boron oxide (B2O3) as glass formers and having a refractive index nd of greater than or equal to 1.80, as measured at 587.56 nm, a density of less than or equal to 5.5 g/cm3, as measured at 25° C., and a high transmittance to, particularly to blue light, are provided. Optionally, the glasses may be characterized by a high transmittance in the visible and near-ultraviolet (near-UV) range of the electromagnetic spectrum and/or good glass forming ability.

Abstract: This application provides a model training method and apparatus. The method includes: A first processing node obtains at least one first model; the first processing node processes the at least one first model to generate a first common model; and the first processing node determines a second processing node, where the second processing node is a processing node for a next round of model processing, and the first common model is obtained by the second processing node before the next round of model processing. In technical solutions provided in this application, before the next round of model processing, a processing node for the next round of model processing may be determined based on an actual requirement, to adapt to a change of an application scenario.

Abstract: Methods and apparatus for controlling plasma in a process chamber leverage an RF termination filter which provides an RF path to ground. In some embodiments, an apparatus may include a DC filter configured to be electrically connected between a DC power supply and electrodes embedded in an electrostatic chuck where the DC filter is configured to block DC current from the DC power supply from flowing through the DC filter and an RF termination filter configured to be electrically connected between the DC filter and an RF ground of the process chamber where the RF termination filter is configured to adjust an impedance of the electrodes relative to the RF ground.

Abstract: The present disclosure provides a display apparatus and a driving method thereof. The display apparatus includes a display panel including a plurality of pixel islands arranged at intervals in a row direction and a column direction, each pixel island being provided with a plurality of sub-pixels arranged at intervals in the row direction; and a light splitting component, disposed on a display side of the display panel and including a plurality of light splitting structures extending in the column direction and continuously arranged in the row direction. In the row direction, every at least two adjacent light splitting structures are one light splitting repeating unit. Each light splitting repeating unit covers one column of the pixel islands correspondingly. In one of the pixel islands, relative positions of all sub-pixels to the corresponding light splitting structures are complementary.

Abstract: Systems and techniques are described for large field of view imaging. A device's first image sensor captures a first image based on first light from a scene redirected by a light redirection element (e.g., a first prism and/or first reflective surface), and the device's second image sensor captures a second image based on second light from the scene redirected by the light redirection element (e.g., a second prism and/or second reflective surface). The device can modify the first image and/or second image using perspective distortion correction and/or to align one or more properties of two respective depictions of a shared portion of a scene in the two images. The one or more properties can include brightness, contrast, positioning, sharpness, tint, hue, and/or saturation. The device can generate a combined image with a large field of view and smooth transitions by combining the first image and the second image.

Abstract: Disclosed are a dynamic error measurement apparatus, system, and method for an electricity meter. The measurement apparatus includes a test signal generation unit configured to generate a voltage test signal and two-circuit current test signals, output the voltage test signal to a measurement unit, and output the two-circuit current test signals to the measurement unit and a current summation unit; the measurement unit configured to determine two-circuit electric energy values based on the voltage test signal and the two-circuit current test signals, and output the two-circuit electric energy values to a calculation control unit; the current summation unit configured to determine a combined current signal based on the two-circuit current test signals; and the calculation control unit configured to determine a total electric energy value based on the two-circuit electric energy values. The system includes a standard meter and a measurement apparatus.

Abstract: An anti-force brake testing platform for an electric vehicle based on model predictive control (MPC) includes a first testing unit; a second testing unit; a third testing unit; a fourth testing unit; a wheelbase adjustment device; and a control cabinet system. The first and second testing units are structurally identical and have the same height, and are provided at the same horizontal foundation plane, with each including a first driving device, a first roller group, a first lifting device, a steering device, a frame, and a first control and test device. The third and fourth testing units are structurally identical, with each including a second driving device, a second roller group, a second lifting device, an anti-slip stopping mechanism, a first fixed base frame, a locking mechanism, and a second control and test device. The wheelbase adjustment device includes a second fixed base frame and a movable stand.

Abstract: Provided are a fused bicyclic heteroaryl amide compound as a protein aggregation inhibitor, as well as the use of such compound in the treatment or prevention of neurodegenerative diseases characterized by protein aggregation, such as Alzheimer's disease, Parkinson's disease, frontotemporal dementia, dementia with Lewy bodies, Parkinson's disease dementia, multiple system atrophy, amyotrophic lateral sclerosis, Huntington's disease, and cancer.

Abstract: A display device and a driving method therefor are disclosed. The display device comprises: a display panel, the display panel including a plurality of pixel islands arranged in an array in a row direction and a column direction, and each pixel island including n sub-pixels arranged at intervals in the row direction, where n is an integer greater than 1; and a light splitting assembly located on the display side of the display panel, the light splitting assembly including a plurality of light splitting repeating units which extend in the column direction and are successively arranged in the row direction, each light splitting repeating unit including M light splitting structures which extend in the column direction and are successively arranged in the row direction, each light splitting repeating unit correspondingly covering K columns of pixel islands, M and K being not equal.

Abstract: Disclosed are an advanced persistent threat (APT) detection method and system based on a continuous-time dynamic heterogeneous graph network (CDHGN). The method includes: selecting network interaction event data, extracting entities from the network interaction event data as source nodes and target nodes, extracting an interaction event occurring between a source node and a target node as an edge, and determining a type and an attribute of a node, a type and an attribute of the edge, and a moment at which an interaction event occurs, to obtain a continuous-time dynamic heterogeneous graph; converting each type of edge in the continuous-time dynamic heterogeneous graph into a vector by a CDHGN encoder, to obtain an embedding representation by a CDHGN decoder to obtain a detection result of whether each type of edge is an abnormal edge, to intercept an APT attack.

Abstract: A knotter, including: a driving structure; a punching and shearing clip, a clip mouth of the punching and shearing clip having a first position in an open state, and a second position in a punching state when driven by the driving structure; and scissor having a first position in an open state when driven by the driving structure, and a second position in a shearing state when driven by the driving structure. The second position of the scissor is synchronized with the second position of the punching and shearing clip. The disclosure effectively solves the problem that the shearing knife of the knotter in the related art is unstable when cutting the suture line.

Abstract: Provided herein is an organic solvent to solve silicone polymer, to coat the silicone polymer on at least a portion of the surface of an article such as needles, syringes, stoppers and medicine bottles.

Abstract: The present disclosure provides a screen detection method, an apparatus and a device, a computer program and a readable medium, and belongs to the technical field of screens. The method includes: receiving a cylindrical lens detection instruction for a target screen, wherein the cylindrical lens detection instruction at least includes target viewpoints; acquiring browsing images shot from the target screen under the target viewpoints in response to the detection instruction, wherein the target screen is a screen of which the light emission side is provided with cylindrical lenses; using the browsing images as viewpoint images under the condition that the browsing images include target contents; and outputting detection parameters of the cylindrical lenses on the target screen based on image parameters of the viewpoint images.

Abstract: The invention relates to a method of treatment comprising administering a long-acting mutant human fibroblast growth factor to a subject in need thereof. The said long-acting mutant human fibroblast growth factor is mPBG-CH2-N?H-mFGF21, wherein mFGF21 consists of SEQ ID NO:1, and the said new use consists of a method of treating non-alcoholic steatohepatitis.

Abstract: A terminal body comprises a first terminal plate having a first mating part and a first welding part connected to the first mating part, and a second terminal plate. The second terminal plate has a second mating part, and a second welding part connected to the second mating part. The first mating part and the second mating part are spaced relative to each other in a height direction of the terminal body to allow for the insertion of a mating terminal. The first welding part is stacked and welded on the second welding part. The first terminal plate and the second terminal plate are two independent components formed separately.

Abstract: The present invention relates to a compound as shown in formula (I). The present invention also provides a composition and preparation containing the compound, and a method for using and preparing the compound.

Abstract: An automatic scanning system for tunnel walls constructed by open-type TBM, to realize the automatic, accurate, rapid and omnidirectional scanning of tunnel wall. The system comprises a three-dimensional laser scanner, a walking unit, a circumferential track, several connecting rods and a remote-control unit; wherein the three-dimensional laser scanner is fixed on the walking unit. The walking unit is provided on the circumferential track and configured to walk on the circumferential track at a set speed and a set number of walking cycles according to a control instruction. The circumferential track is fixed on the main beam of open-type TBM through the connecting rods and located between the roof bolter and cylinder of gripper shoe. The remote-control unit is configured to issue the control instruction and control the three-dimensional laser scanner to scan the tunnel wall and transmit the scanning data using set scanning parameters.