Abstract: The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.

Abstract: A position locking device is disclosed for a draw-out circuit breaker. In at least one embodiment, the position locking device includes a screw rod, a catching plate, a positioning plate, a locking plate, and a push rod. The screw rod has key ways. The catching plate has a catching plate hole and a protrusion that can be inserted into the key ways. Positioning notches for limiting OFF, TEST, and ON positions of the circuit breaker are formed on the top surface of the positioning plate, and corresponding protruding platforms are disposed on the bottom surface. One end of the locking plate bears against the bottom surface of the positioning plate, and the other end is locked to or unlocked from an outward protruding platform of the catching plate. One end of the push rod passes through the catching plate hole, and has an inclined surface. When the push rod is pushed, the inclined surface makes the catching plate leave the key ways.

Abstract: An improved robotic hand in which the palm section enables it to be capable of a wide range of movement with the ability to have good precision and control. The palm section consists of a plurality of parts which are able to move or flex relative to each other. Preferably, it is constructed as five bar spherical linkage having two degrees of freedom.

Abstract: The invention relates to compositions and methods for interfering with the DNA repair of double strand breaks (DSBs). The invention discloses double-stranded nucleic acid molecules that act as baits and hijack the holocomplex of enzymes responsible for DNA DSB sensing, signaling and/or repair pathways, in particular the non-homologous end joining (NHEJ) pathway of DSB repair. The invention discloses the use of these molecules as a standalone anticancer drug in an efficient amount to be introduced in the tumor cell nuclei in order to trigger their death.

Abstract: A driving device of an electric motor for generating power is characterized by that: said driving device comprises: multiples support bars arranged at interval, a drive shaft penetrating the support bars, at least four weight wheels penetrated and secured by the drive shaft, a first driving wheel pivotally mated with the drive shaft and driven by the electric motor, and at least a second driving wheel pivotally mated with the drive shaft and used to energize the generator; four weight wheels are arranged at both sides of every support bar in pairs, so that the driving device forms a two driving portions, and the support bar is fitted with a drive bearing penetrated by the drive shaft.

Abstract: A system for optimizing display colors of a digital light processing projector includes a color analyzer, and a central processing module. The color analyzer is configured for detecting a first image produced by the projector to obtain actual brightness proportions of red, green, and blue light components associated with the first image, and obtaining a color coordinate of the first image at the actual brightness proportions. The central processing module is configured for adjusting the actual brightness proportions to pre-set brightness proportions to form a second image. The color analyzer detects the second image to obtain a color coordinate thereof. The central processing module adjusts the color coordinate of the second image to a pre-set standard color coordinate, and changes the first gamma curve of the projector to a second gamma curve according to the adjusted color coordinate of the second image.

Abstract: A toy figure is disclosed herein, the toy figure having a main body portion; a pair of appendages movably secured to the main body portion for movement from a first position to a second position and back to the first position; and a removably body portion removably secured to the main body portion, wherein the pair of appendages grasp the removably body portion when they are moved to the second position and the removably body portion is removably secured to the main body portion, wherein the removably body portion is subsequently removed from the main body portion by the pair of appendages as they are moved back towards the first position from the second position.

Abstract: The present invention provides a radio-opaque composition comprising a cleavable, preferably enzymatically-cleavable, derivative of a physiologically tolerable organoiodine compound and a non-acrylic polymer wherein said derivative is incorporated in said non-acrylic polymer.

Abstract: A position locking device is disclosed for a draw-out circuit breaker. In at least one embodiment, the position locking device includes a screw rod, a catching plate, a positioning plate, a locking plate, and a push rod. The screw rod has key ways. The catching plate has a catching plate hole and a protrusion that can be inserted into the key ways. Positioning notches for limiting OFF, TEST, and ON positions of the circuit breaker are farmed on the top surface of the positioning plate, and corresponding protruding platforms are disposed on the bottom surface. One end of the locking plate bears against the bottom surface of the positioning plate, and the other end is locked to or unlocked from an outward protruding platform of the catching plate. One end of the push rod passes through the catching plate hole, and has an inclined surface. When the push rod is pushed, the inclined surface makes the catching plate leave the key ways.

Abstract: The invention relates to compositions and methods for interfering with the DNA repair of double strand breaks (DSBs). The invention discloses novel double-stranded nucleic acid molecules. that act as baits and hijack the holocomplex of enzymes responsible of DNA DSB sensing, signaling and/or repair pathways, in particular the non homologous end joining (NHEJ) pathway of DSB repair. The invention discloses the use of these molecules as adjuvant compositions to be used in association with a DNA breaking treatment, particularly radiotherapy or chemotherapy, in combination with a pharmaceutically acceptable carrier, in an efficient amount to be introduced in the tumor cell nuclei in order to neutralize transiently their DNA repair capacity and trigger their death.

Abstract: A crank handle apparatus for a draw-out circuit breaker is disclosed. In at least one embodiment, the crank handle apparatus includes a crank, a locating piece, a button, a locking plate provided with a projecting part, and a retractable connecting link. A taken-in locking slot and a draw-out locking slot are provided in both ends of the crank. The locating piece includes a drawing gear which is wedged into the taken-in locking slot and the drawn-out locking slot respectively, and a locating slope which is connected with a locating spring apparatus. A button slope is provided in the button. A first resetting spring apparatus is provided in the button slope. A slope part of the button slope and a slope part of the locating slope are opposite and are in contact with each other. The projecting part is suppressed against or departed from the locating piece when the locking plate is moved.

Abstract: An input method for a communication device includes the steps of displaying a result box and a dial ring comprising a plurality of buttons on a touch screen of the communication device; receiving a touch and slide operation on a button; recognizing the touch and slide operation and rotating the dial ring according to the slide operation; and displaying information represented by the touched button in the result box when the touched button rotates to a predetermined position. People who are used to rotary dial phone can use the input method without difficulty.

Abstract: The invention relates to double-stranded nucleic acid fragments comprising a chemically modified backbone and at least 4-1000 bp, preferably 8-500 bp, and most preferably 16-200 bp. The disclosed molecules (DRIL molecules) may interfere with DNA damage signaling and repair pathways, in particular the non homologous NHEJ pathway of double-stranded break repair. The invention discloses the application of the DRIL molecules as adjuvant compositions to be used in association with a DNA breaking treatment, particularly radiotherapy or chemotherapy, in combination with a pharmaceutically acceptable carrier, in an efficient amount to be introduced in the tumoral cell nuclei in order to trigger DNA repair induced lethality (DRIL in short) of tumoral cells/tissues.

Abstract: An exemplary gamma correction method for use in a display device is disclosed. The display device includes a lamp, and a memory. The lamp is configured to generate light which is modulated into a visual image. The memory is configured for storing a plurality of gamma correction settings. The gamma correction method comprising: measuring service time of the lamp; receiving input displayable signals; and correcting the input displayable signals using a corresponding gamma correction setting, based on the measured service time of the lamp.

Abstract: The invention relates to compositions and methods for interfering with the DNA repair of double strand breaks (DSBs). The invention discloses novel double-stranded nucleic acid molecules. that act as baits and hijack the holocomplex of enzymes responsible of DNA DSB sensing, signaling and/or repair pathways, in particular the non homologous end joining (NHEJ) pathway of DSB repair. The invention discloses the use of these molecules as adjuvant compositions to be used in association with a DNA breaking treatment, particularly radiotherapy or chemotherapy, in combination with a pharmaceutically acceptable carrier, in an efficient amount to be introduced in the tumor cell nuclei in order to neutralize transiently their DNA repair capacity and trigger their death.

Abstract: A system for optimizing display colors of a digital light processing projector includes a color analyzer, and a central processing module. The color analyzer is configured for detecting a first image produced by the projector to obtain actual brightness proportions of red, green, and blue light components associated with the first image, and obtaining a color coordinate of the first image at the actual brightness proportions. The central processing module is configured for adjusting the actual brightness proportions to pre-set brightness proportions to form a second image. The color analyzer detects the second image to obtain a color coordinate thereof. The central processing module adjusts the color coordinate of the second image to a pre-set standard color coordinate, and changes the first gamma curve of the projector to a second gamma curve according to the adjusted color coordinate of the second image.

Abstract: A burn-in test system for a plurality of projection devices includes a plurality of light sensing modules, a data collecting module, a data receiving module, and a data processing module. Each of the light sensing modules is configured for receiving light from the respective projection device and converting the light into an electrical signal. The data collecting module is configured for converting the electrical signals from the light sensing modules into a plurality of digital signals and transmitting the digital signals. The data receiving module is configured for receiving the digital signals from the data collecting module. The data processing module is configured for processing the digital signals provided from the data receiving module to obtain age information of the projection devices.

Abstract: The invention relates to compositions and methods for interfering with the DNA repair of double strand breaks (DSBs). The invention discloses novel double-stranded nucleic acid molecules that act as baits and hijack the holocomplex of enzymes responsible of DNA DSB sensing, signaling and/or repair pathways, in particular the non homologous end joining (NHEJ) pathway of DSB repair. The invention discloses the use of these molecules as adjuvant compositions to be used in association with a DNA breaking treatment, particularly radiotherapy or chemotherapy, in combination with a pharmaceutically acceptable carrier, in an efficient amount to be introduced in the tumor cell nuclei in order to neutralize transiently their DNA repair capacity and trigger their death.

Abstract: The invention relate to the use of a compound of formula A-B—C Wherein A is a DNA sequence-specific ligand capable of simultaneously and specifically recognizing a sequence common to genes of pathological interest; B is a linker arm, said linker arm being bound to the 3? end of A; C is a topoisomerase I posion; for the preparation of a drug for the treatment of a disease brought about by the expression of a gene and said gene is inhibited by the stabilized topoisomerase I-mediated DNA cleavage. Application, particularly, for the treatment of infective microorganism or virus, dismetabolic disease and autoimmune disease.

Abstract: An I/O shield used in an electronic apparatus is provided. The electronic apparatus comprises a casing having an opening. The I/O shield comprises a body and at least a flexible lateral plate. The body has an edge with many protrusions arranged thereon. The flexible lateral plate has a first lateral edge and a second lateral edge parallel to the first lateral edge. The first lateral edge is disposed on the edge. The flexible lateral plate tilts towards the protrusions, and a surface of the flexible lateral plate faces the protrusions. When a rim of the opening is situated between the protrusions and the flexible lateral plate, the flexible lateral plate forms a bend structure between the first lateral edge and the second lateral edge, so that part of the surface near the second lateral edge presses the rim and clamps the rim of the opening together with the protrusions.