Patents by Inventor Jian Xie

Jian Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210122755
    Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
    Type: Application
    Filed: December 14, 2020
    Publication date: April 29, 2021
    Applicant: G1 Therapeutics, Inc.
    Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
  • Patent number: 10986932
    Abstract: An adjustable bed system includes first and second frames; a back lifting assembly having a back lifting bracket pivotally connected to the first frame and a back lifting actuator pivotally connected between the back lifting bracket and the first frame for operably driving the back lifting bracket to pivotally move in an upward or downward rotating direction relative to the first frame; a leg lifting assembly having a leg lifting bracket pivotally connected to the second frame structure and a leg lifting actuator pivotally connected between the leg lifting bracket and the second frame for operably driving the leg lifting bracket to pivotally move in an upward or downward rotating direction relative to the second frame; and a foldable connection mechanism connecting the first and second frames such that the first and second frames are pivotally foldable relative to one another at the connection mechanism.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: April 27, 2021
    Assignee: NISCO CO., LTD
    Inventors: Wei Wang, Jian Xie, Yifan Mao
  • Patent number: 10960110
    Abstract: Iron-based biodegradable metals and the method of fabricating are disclosed. The iron-based biodegradable metals, which have an accelerated degradation rate and a yield strength similar to stainless steel, comprises a composite structure of multiple iron layers separated by thin alloying metallic layers. The composite structure are built layer by layer using additive manufacturing technologies. The iron-based biodegradable metals can be fabricated into a small diameter tube for laser cutting into implantable bare metal stents or drug eluting stents with biodegradable polymer coating. The iron-based biodegradable metals can be fabricated and/or machined into orthopedic implants.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: March 30, 2021
    Assignee: Jian Xie
    Inventor: Jian Xie
  • Publication number: 20210092195
    Abstract: An information push method and device are provided, relating to the technology field of data transmission. The detailed implementation solution is: acquiring a set of to-be-pushed information; determining to-be-pushed information corresponding to a push end from the set of to-be-pushed information, according to a triggering condition and historical behavior information of the push end associated with information on a target user; and pushing the to-be-pushed information corresponding to the push end, in a case that the triggering condition of the push end is triggered. In the application, a unified configuration and push of the to-be-pushed information is implemented for multiple push ends associated with the information on the target user, effectively improving gains of information push and the number of pushed information.
    Type: Application
    Filed: February 11, 2020
    Publication date: March 25, 2021
    Inventors: Zhongji Fan, Jian Xie
  • Publication number: 20210069384
    Abstract: The present invention relates to a degradable vascular stent capable of avoiding late restenosis, comprising a base region formed by a polylactic acid based polymer; at least one storage region in which an active agent is stored; and an outer layer of a drug sustained release coating covered on the base region and/or the storage region. Before the mass of the polylactic acid based polymer is decreased by 10-20%, the active agent is retained in structural units of the polylactic acid based polymer. After the mass of the polylactic acid based polymer is decreased by 10-20%, the active agent is released from the storage region. The base region provides a supporting capacity for ensuring patency of blood vessels; the drug sustained release coating is used for drug release in an early stage; and the active agent only works in late degradation of the stent to avoid late restenosis.
    Type: Application
    Filed: January 9, 2018
    Publication date: March 11, 2021
    Inventors: Zheng Wei, Bin Huang, Jian Xie, Yunhong Mu
  • Publication number: 20210052085
    Abstract: An adjustable bed includes a frame structure; a plurality of platforms disposed on the frame structure; and an adjustable assembly coupled with the frame structure and the plurality of platforms for operably adjusting one or more of the plurality of platforms in desired positions; and an aromatherapy system attached onto the one or more platforms for producing desired fragrance in a surrounding space of the adjustable bed so as to promote health and well-being of a user. Each aromatherapy device is configured to produce a fragrance when said aromatherapy device is turned on, and one or more working modes. The fragrance is identical to or different from that produced by other aromatherapy device of the one or more aromatherapy devices.
    Type: Application
    Filed: August 11, 2020
    Publication date: February 25, 2021
    Inventors: Wei Wang, Jian Xie, Yifan Mao
  • Patent number: 10912391
    Abstract: An adjustable bed includes: a head frame assembly; a foot frame assembly; a knockdown connecting bracket; a slidable assembly having a pair of slidable assembly sides slidable within a pair of lower C steel brackets in a slidable assembly upward direction or a slidable assembly downward direction; a plurality of slidable assembly angle steels; a pair of head lift arm bracket assemblies; a second head tilt angle bracket; a head tilt platform; a head lift platform; a lumbar lift bracket assembly; an upper seat platform; a support platform; a lower seat platform; a head lift motor, secured to the head frame assembly for driving the pair of head lift arm bracket assemblies in a head lift forward direction or a head lift backward direction; and a head support tube, having an upper end pivotally connected to a L bracket and a lower end connected to the head lift platform.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: February 9, 2021
    Assignee: NISCO CO., LTD
    Inventors: Wei Wang, Jian Xie, Yifan Mao
  • Publication number: 20210014347
    Abstract: This application provides a mobile terminal which includes two housings that are rotatably connected, and a flexible screen component fastened to the two housings, wherein the flexible screen component is fastened to two groups of position-limiting components, one group of sliding slots is disposed on each housing, the two groups of position-limiting components are respectively located in two groups of sliding slots in a one-to-one correspondence, and the two groups of position-limiting components are configured to limit a relative vertical distance between the flexible screen component and the housings.
    Type: Application
    Filed: February 6, 2020
    Publication date: January 14, 2021
    Inventors: Chunjun Ma, Yu Liu, Jian Xie, Zheng Li, Zhangmin Bao, Chunyuan Fang
  • Patent number: 10886540
    Abstract: Functionalized graphene comprising graphene, a metal dispersed throughout the graphene, wherein the metal comprises Pt, Rh, Pd, Ag, Au, Ni, Os, Ir, alloys thereof, oxides thereof, or mixtures thereof, and a first functional group covalently bonded to the graphene, wherein the first functional group comprises sulfonate, SO3?, Carboxylate, COO?, a tertiary amine, NR3+, where R is H, alkyl, aryl, or combinations thereof, polybenzimidazole (PBI), poly(ethylene oxide) (PEO), polyphenylene oxide (PPO), polyaniline, or mixtures thereof are disclosed. Methods of manufacture are also disclosed.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: January 5, 2021
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Jian Xie, Zhe-Fei Li, Le Xin
  • Publication number: 20200397147
    Abstract: An adjustable bed includes a bed frame supporting a plurality of platforms having at least a head platform and a back platform, a back lifting assembly, a foot lifting assembly, a base frame pivotally and detachably connected to the bed frame, a bed frame tilting actuator pivotally connected to the bed frame and the base frame for operably adjusting the bed frame from the horizontal position to the sloping position relative to the base frame, or vice versa. The adjustable bed also includes a head platform tilting actuator pivotally connected to the head platform and the back platform for operably adjusting the head platform in a tilting position or a flat position relative to the back platform.
    Type: Application
    Filed: June 8, 2020
    Publication date: December 24, 2020
    Inventors: Zhong Ren, Wei Wang, Jian Xie, Yifan Mao
  • Publication number: 20200397782
    Abstract: Forms of 6-(3-chloro-4-cyclopropoxyphenyl)pyrimidine-4-carboxylic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I and salts or co-crystals thereof.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 24, 2020
    Inventors: Leticia M. Toledo-Sherman, Celia Dominguez, Vinod Khetarpal, Travis Lee Houston, Stephan D. Parent, Jian-xie Chen, Charlie Montgomery, Geetha Banda
  • Patent number: 10872108
    Abstract: Embodiments of the disclosure disclose a method and apparatus for updating a multimedia playlist. An embodiment of the method comprises: sending a current multimedia content playlist to a playing terminal; analyzing, in response to receiving a voice updating request from a user to update currently played multimedia content in the current multimedia content playlist, the voice updating request to obtain an updating instruction corresponding to the currently played multimedia content; searching in a preset multimedia content database based on the updating instruction to generate an optimized multimedia playlist; and sending the optimized multimedia playlist to the playing terminal. With the embodiment, a matching degree between the obtained optimized multimedia playlist and the user's updating instruction is higher, the search operation is simpler, and then the search consumes less hardware resources.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: December 22, 2020
    Assignee: Baidu Online Network Technology (Beijing) Co., Ltd.
    Inventors: Guang Lu, Shiquan Ye, Xiajun Luo, Qiang Ju, Jian Xie
  • Patent number: 10865210
    Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: December 15, 2020
    Assignee: G1 Therapeutics, Inc.
    Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
  • Publication number: 20200359806
    Abstract: An adjustable bed system includes a first frame structure; a second frame structure disposed on and moveably coupled to the first frame structure; a back lifting assembly; a leg lifting assembly; and a plurality of fans coupled with platforms for operably providing air circulation in bed surrounding. The back lifting assembly comprises a back lifting bracket pivotally connected to the second frame structure, and a back lifting actuator pivotally connected between the back lifting bracket and the first frame structure for operably driving the back lifting bracket to pivotally move in an upward or downward rotating direction. The leg lifting assembly comprises a leg lifting bracket pivotally coupled to the first frame structure, and a leg lifting actuator pivotally connected between the leg lifting bracket and the second frame structure for operably driving the leg lifting bracket to pivotally move in an upward or downward rotating direction.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 19, 2020
    Inventors: Wei Wang, Jian Xie, Jian Sun
  • Publication number: 20200221882
    Abstract: An adjustable bed system includes a frame structure, a back lifting assembly and a leg lifting assembly pivotally connected to the frame structure, platforms having a plurality of openings, disposed on the frame structure and operably coupled with the back and leg lifting assemblies, a mattress having a plurality of through holes and disposed on the platforms so that the plurality of through holes is aligned with the plurality of openings, respectively, and a plurality of fans installed in the plurality of openings of the platforms such that each fan is in communication with a respective through hole of the mattress for operably moving air via said through hole into the mattress body and outputting the air from the top surface of the mattress. Positions of upper and lower portions of the mattress are adjustable based on operations of the back and assemblies.
    Type: Application
    Filed: January 2, 2020
    Publication date: July 16, 2020
    Inventors: Wei Wang, Jian Sun, Jian Xie, Qiaoyan Yang, Matthew Howard Sweeting
  • Publication number: 20200214460
    Abstract: An adjustable bed includes: a head frame and a foot frame; a head lifting assembly including a head lifting bracket pivotally connected to the head frame, and a head lifting actuator pivotally connected between the head lifting bracket and the head frame for operably driving the head lifting bracket to pivotally move in an upward rotating direction or a downward rotating direction; a foot lifting assembly including a foot lifting bracket pivotally connected to the foot frame, and a foot lifting actuator pivotally connected between the foot lifting bracket and the foot frame for operably driving the foot lifting bracket to pivotally move in an upward rotating direction or a downward rotating direction; and a folding mechanism connecting the head frame and the foot frame such that the head frame and the foot frame are pivotably foldable to one another at the folding mechanism.
    Type: Application
    Filed: December 30, 2019
    Publication date: July 9, 2020
    Inventors: Wei Wang, Jian Xie, Yifan Mao, Hailong Sun, Jinquan Ren
  • Publication number: 20200214461
    Abstract: An adjustable bed includes: a head frame assembly; a foot frame assembly; a knockdown connecting bracket; a slidable assembly having a pair of slidable assembly sides slidable within a pair of lower C steel brackets in a slidable assembly upward direction or a slidable assembly downward direction; a plurality of slidable assembly angle steels; a pair of head lift arm bracket assemblies; a second head tilt angle bracket; a head tilt platform; a head lift platform; a lumbar lift bracket assembly; an upper seat platform; a support platform; a lower seat platform; a head lift motor, secured to the head frame assembly for driving the pair of head lift arm bracket assemblies in a head lift forward direction or a head lift backward direction; and a head support tube, having an upper end pivotally connected to a L bracket and a lower end connected to the head lift platform.
    Type: Application
    Filed: July 9, 2019
    Publication date: July 9, 2020
    Inventors: Wei Wang, Jian Xie, Yifan Mao
  • Publication number: 20200214462
    Abstract: An adjustable bed system includes first and second frames; a back lifting assembly having a back lifting bracket pivotally connected to the first frame and a back lifting actuator pivotally connected between the back lifting bracket and the first frame for operably driving the back lifting bracket to pivotally move in an upward or downward rotating direction relative to the first frame; a leg lifting assembly having a leg lifting bracket pivotally connected to the second frame structure and a leg lifting actuator pivotally connected between the leg lifting bracket and the second frame for operably driving the leg lifting bracket to pivotally move in an upward or downward rotating direction relative to the second frame; and a foldable connection mechanism connecting the first and second frames such that the first and second frames are pivotally foldable relative to one another at the connection mechanism.
    Type: Application
    Filed: January 21, 2020
    Publication date: July 9, 2020
    Inventors: Wei Wang, Jian Xie, Yifan Mao
  • Publication number: 20200214463
    Abstract: An adjustable bed system includes first and second frames; a back lifting assembly having a back lifting bracket pivotally connected to the first frame and a back lifting actuator pivotally connected between the back lifting bracket and the first frame for operably driving the back lifting bracket to pivotally move in an upward or downward rotating direction relative to the first frame; a leg lifting assembly having a leg lifting bracket pivotally connected to the second frame structure and a leg lifting actuator pivotally connected between the leg lifting bracket and the second frame for operably driving the leg lifting bracket to pivotally move in an upward or downward rotating direction relative to the second frame; and a foldable connection mechanism connecting the first and second frames such that the first and second frames are pivotally foldable relative to one another at the connection mechanism.
    Type: Application
    Filed: January 21, 2020
    Publication date: July 9, 2020
    Inventors: Jian Xie, Yifan Mao, Jinquan Ren, Hailong Sun
  • Patent number: 10643610
    Abstract: Embodiments of this disclosure disclose a voice interaction based method and apparatus for generating a multimedia playlist. An embodiment of the method comprises: acquiring first voice request information for playing multimedia resources; identifying a key tag for indicating a characteristic attribute of the multimedia resources in the first voice request information; finding the multimedia resources having the key tag in a multimedia resource library; and generating a multimedia playlist based on the found multimedia resources. The embodiment realizes automatic generation of multimedia playlists and improves the efficiency of voice service.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: May 5, 2020
    Assignee: BAIDU ONLINE NETWORK TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Guang Lu, Shui Liu, Xiajun Luo, Shiquan Ye, Xiangjie Yin, Qiang Ju, Jian Xie