Abstract: An online system receives information describing items for sale posted by non-merchant users of the online system and retrieves a first set of attributes associated with each non-merchant user. The online system also receives information describing a first set of user interactions by potential purchasing users with each item and then retrieves a machine-learning model trained to infer a second set of attributes associated with a non-merchant user of the online system, in which the model is trained based on the first set of attributes and the information describing the first set of user interactions. The online system then retrieves information describing a second set of user interactions by potential purchasing users with an item for sale posted by the non-merchant user and uses the model to infer the second set of attributes associated with the non-merchant user based on the information describing the second set of user interactions.

Abstract: An enhanced digital light processing-based mask projection stereolithography method and apparatus are disclosed, where the apparatus comprises: a control platform capable of slicing a model of a to-be-prototyped object into layers, converting the layer into a bitmap, and further dividing the layer into a main body area and boundary filling areas; a digital light processing unit that is controlled by the control platform and capable of emitting a first light beam used for the corresponding main body area of the layer of the to-be-prototyped object; and a laser marking unit that is controlled by the control platform and capable of emitting a second light beam used for the corresponding boundary filling areas of the layer of the to-be-prototyped object. The present invention can not only implement high-speed prototyping but also avoid an edge distortion, thereby improving precision of object prototyping.

Abstract: A method of detecting flow instability includes insonating an area of interest with ultrasound wave pulses, acquiring radio frequency (RF) data from echo pulses of the ultrasound wave pulses, processing the RF data, and deriving a Doppler band-width from the processed RF data by AR modeling. Also described herein is a device for detecting flow instability. The device includes an emitter configured to insonate ultrasound wave pulses on an area of interest, a receiver configured to acquiring radio frequency (RF) data from echo pulses of the ultrasound wave pulses, and a processor configured to process the RF data, and derive a Doppler band-width from the processed RF data by AR modeling.

Abstract: A servo driver includes: a driver, a pulse conversion module and a pulse interface. The pulse conversion module is connected between the pulse interface and the driver, and the pulse conversion module converts the type of a pulse control signal received by the pulse interface from an upper computer or a PLC and then outputs same to the driver. The type of the pulse control signal includes at least one of a clockwise and counter-clockwise pulse control type, a pulse plus direction control type and an AB-phase input control type. In an embodiment, the pulse conversion module is used to convert the type of the pulse control signal from the upper computer or the PLC, so that the driver can be compatible with an upper computer or a PLC having a different control signal type.

Abstract: A bone implant adapted to be implanted in a bone structure having a bone tissue, a cartilage tissue, and being formed with a hole is provided. The bone implant includes a scaffold disposed in the hole for connecting with the bone tissue, a connecting layer disposed on the scaffold, and a porous surface layer. The connecting layer includes a bottom portion connected to the scaffold and an extension portion extending from the bottom portion and formed with a plurality of receiving chambers. The porous surface layer is connected to the extension portion and includes a plurality of filler portions respectively filling the receiving chambers, and a tissue-connecting portion configured for connecting with the cartilage tissue.

Abstract: There is provided a method of identifying risk of cancer in a human subject, the method comprising: determining in a biological sample of the subject, whether a copy number amplification of at least one continuous genomic region specific to human chromosome 1q21 is present, wherein the presence of a copy number amplification of the region specific to human chromosome 1q21 represents an elevated risk of cancer in the subject and the at least one continuous genomic region is selected from the group consisting of: a human TUFT1 gene or a gene from the human S100 family. It is also provided a method of treating cancer in a subject determined to have a copy number amplification of a region specific to human chromosome 1q21, the method comprising administering a therapeutic agent capable of suppressing IRAK1, IRAK4 or a S100 family member, such as Pacritinib. There are also provided a method of treating cancer, related polynucleotides, kits, therapeutic agents and use of the therapeutic agents.

Abstract: A flame-retardant and abrasion-resistant composite is provided, and includes a nano-porous material and a polymer. The nano-porous material includes a plurality of powder having a particle size of less than 20 micrometers. A specific surface area of the powder is 50 to 3,000 m2/g. An amount of the powder is 50 parts per million to 30 wt %. The nano-porous material is dispersedly bound to the polymer and a limiting oxygen index of the composite is greater than or equal to 24%.

Abstract: Various aspects and embodiments disclosed herein relate generally to the modelling, treatment, reduction of resistance to the treatment, prevention, and/or diagnosis of diseases characterized by the formation of cancers. Embodiments include methods of treating cancer, comprising the steps of: providing a patient diagnosed with cancer with a therapeutic regime that includes at least one therapeutically effective dose of at least one agent that reduces the activity of at least one DNA damage/repair pathway. Other embodiments include methods of treating cancer, comprising the steps of: treating a patient diagnosed with cancer with a combination of therapeutic agents that includes at least one therapeutically effective anti-cancer agent and at least one compound that reduces the activity of at least one DNA damage/repair pathway.

Abstract: This document relates to methods and materials involved in modulating deubiquitinases (e.g., USP10 polypeptides) and/or ubiquitinated polypeptides (e.g., tumor suppressor polypeptides or mutant versions of tumor suppressor polypeptides). For example, methods and materials for increasing deubiquitinase (e.g., a USP10 polypeptide) expression or activity, methods and materials for decreasing deubiquitinase (e.g., a USP10 polypeptide) expression or activity, methods and materials for stabilizing tumor suppressor polypeptides (e.g., wild-type p53 polypeptides), methods and materials for de-stabilizing mutant versions of tumor suppressor polypeptides (e.g., mutant p53 polypeptides), and methods and materials for reducing cancer cell proliferation, increasing cancer cell apoptosis, and/or treating cancer (e.g., cancers having reduced levels of wild-type p53 polypeptides or cancers having increased levels of mutant p53 polypeptides) are provided.

Abstract: A spacer for a membrane module, the spacer comprising: a plurality of first filaments defining a plurality of fluid flow channels, in use the plurality of fluid flow channels being adjacent a membrane of the membrane module; and a plurality of second filaments provided on the plurality of first filaments and extending into the fluid flow channels, the second filaments moveable relative to the first filaments in response to an external stimulus during flow of fluid in the fluid flow channels.

Abstract: A spacer for a membrane module, the spacer comprising: a plurality of first filaments defining a plurality of fluid flow channels, in use the plurality of fluid flow channels being adjacent a membrane of the membrane module; and a plurality of second filaments provided on the plurality of first filaments and extending into the fluid flow channels, the second filaments moveable relative to the first filaments in response to an external stimulus during flow of fluid in the fluid flow channels.

Abstract: This document relates to methods and materials involved in modulating deubiquitinases (e.g., USP10 polypeptides) and/or ubiquitinated polypeptides (e.g., tumor suppressor polypeptides or mutant versions of tumor suppressor polypeptides). For example, methods and materials for increasing deubiquitinase (e.g., a USP10 polypeptide) expression or activity, methods and materials for decreasing deubiquitinase (e.g., a USP10 polypeptide) expression or activity, methods and materials for stabilizing tumor suppressor polypeptides (e.g., wild-type p53 polypeptides), methods and materials for de-stabilizing mutant versions of tumor suppressor polypeptides (e.g., mutant p53 polypeptides), and methods and materials for reducing cancer cell proliferation, increasing cancer cell apoptosis, and/or treating cancer (e.g., cancers having reduced levels of wild-type p53 polypeptides or cancers having increased levels of mutant p53 polypeptides) are provided.

Abstract: The present disclosure relates to an extreme ultraviolet (EUV) radiation source having a collector mirror oriented to reduce contamination of fuel droplet debris. In some embodiments, the EUV radiation source has a fuel droplet generator that provides a plurality of fuel droplets to an EUV source vessel. A primary laser is configured to generate a primary laser beam directed towards the plurality of fuel droplets. The primary laser beam has a sufficient energy to ignite a plasma from the plurality of fuel droplets, which emits extreme ultraviolet radiation. A collector mirror, configured to focus the extreme ultraviolet radiation to an exit aperture of the EUV source vessel, which is oriented so that a normal vector extending outward from a vertex of the collector mirror intersects a direction of a gravitation force by an angle that is less than 90°.

Abstract: An enhanced digital light processing-based mask projection stereolithography method and apparatus are disclosed, where the apparatus comprises: a control platform capable of slicing a model of a to-be-prototyped object into layers, converting the layer into a bitmap, and further dividing the layer into a main body area and boundary filling areas; a digital light processing unit that is controlled by the control platform and capable of emitting a first light beam used for the corresponding main body area of the layer of the to-be-prototyped object; and a laser marking unit that is controlled by the control platform and capable of emitting a second light beam used for the corresponding boundary filling areas of the layer of the to-be-prototyped object. The present invention can not only implement high-speed prototyping but also avoid an edge distortion, thereby improving precision of object prototyping.

Abstract: Embodiments of a semiconductor processing apparatus are provided. The semiconductor processing apparatus includes a housing and a support base disposed in the housing. The semiconductor processing apparatus also includes a carrying arm movably disposed on the support base and a nozzle device disposed on the carrying arm. The semiconductor processing apparatus further includes a wafer plate disposed on the support base. When a cleaning process is performed, the carrying arm is moved toward the wafer plate, and the nozzle device emits a first gas toward the support base and the wafer plate.

Abstract: The present invention provides a pattern verifying method. First, a target pattern is decomposed into a first pattern and a second pattern. A first OPC process is performed for the first pattern to form a first revised pattern, and a second OPC process is performed for the second pattern to form a second revised pattern. An inspection process is performed, wherein the inspection process comprises an after mask inspection (AMI) process, which comprises considering the target pattern, the first pattern and the second pattern.

Abstract: The present disclosure relates to an extreme ultraviolet (EUV) radiation source having a collector mirror oriented to reduce contamination of fuel droplet debris. In some embodiments, the EUV radiation source has a fuel droplet generator that provides a plurality of fuel droplets to an EUV source vessel. A primary laser is configured to generate a primary laser beam directed towards the plurality of fuel droplets. The primary laser beam has a sufficient energy to ignite a plasma from the plurality of fuel droplets, which emits extreme ultraviolet radiation. A collector mirror, configured to focus the extreme ultraviolet radiation to an exit aperture of the EUV source vessel, which is oriented so that a normal vector extending outward from a vertex of the collector mirror intersects a direction of a gravitation force by an angle that is less than 90°.

Abstract: A reversible handle device includes a housing, a handle portion rotatably disposed on the housing and rotatable relative to a long axis, a reversible member and a stopping member. The reversible member is connected to the handle portion and rotatable relative to the handle portion. The reversible member has a first slot and a second slot for switching the handle portion to be in a first orientation status or in a second orientation status. The stopping member is disposed on a side of the reversible member in a manner of being movable in a direction parallel to the long axis. The stopping member is biased toward the reversible member in the direction parallel to the long axis, such that the stopping member protrudes into the first slot or the second slot. Accordingly, the handle portion is in the first orientation status or in the second orientation status.

Abstract: Systems and methods are disclosed for determining the location where an image was captured. In general, a device such as a smartphone may capture one or more images from a location, such as images of buildings, street signs and the like, and a central system may compare the submitted images to images in an image library to identify matches. The location of the match may then be provided back to the smartphone.

Abstract: The present application provides, among other things, compounds and methods for metathesis reactions. In some embodiments, a provided compound has the structure of formula I, II or III. In some embodiments, R1 of formula I, II or III comprises an electron-withdrawing group. In some embodiments, the present invention provides methods for preparing provided compounds.